YU43305B - Process for obtaining 2-amino-3-benzoyl-phenylacetamides - Google Patents

Process for obtaining 2-amino-3-benzoyl-phenylacetamides

Info

Publication number
YU43305B
YU43305B YU730/83A YU73083A YU43305B YU 43305 B YU43305 B YU 43305B YU 730/83 A YU730/83 A YU 730/83A YU 73083 A YU73083 A YU 73083A YU 43305 B YU43305 B YU 43305B
Authority
YU
Yugoslavia
Prior art keywords
phenylacetamides
benzoyl
amino
obtaining
Prior art date
Application number
YU730/83A
Other versions
YU73083A (en
Inventor
Jr J R Shanklin
D A Shamblee
D A Walsh
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of YU73083A publication Critical patent/YU73083A/en
Publication of YU43305B publication Critical patent/YU43305B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
YU730/83A 1979-09-26 1983-03-28 Process for obtaining 2-amino-3-benzoyl-phenylacetamides YU43305B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7886079A 1979-09-26 1979-09-26

Publications (2)

Publication Number Publication Date
YU73083A YU73083A (en) 1983-12-31
YU43305B true YU43305B (en) 1989-06-30

Family

ID=22146633

Family Applications (3)

Application Number Title Priority Date Filing Date
YU2450/80A YU41734B (en) 1979-09-26 1980-09-25 Process for preparing 1-amino-3-benzone-pnenylacetamides
YU730/83A YU43305B (en) 1979-09-26 1983-03-28 Process for obtaining 2-amino-3-benzoyl-phenylacetamides
YU731/83A YU43306B (en) 1979-09-26 1983-03-28 Process for obtaining 2-amino-3-benzoyl-phenylacetamides

Family Applications Before (1)

Application Number Title Priority Date Filing Date
YU2450/80A YU41734B (en) 1979-09-26 1980-09-25 Process for preparing 1-amino-3-benzone-pnenylacetamides

Family Applications After (1)

Application Number Title Priority Date Filing Date
YU731/83A YU43306B (en) 1979-09-26 1983-03-28 Process for obtaining 2-amino-3-benzoyl-phenylacetamides

Country Status (36)

Country Link
JP (1) JPS5657751A (en)
KR (1) KR840000763B1 (en)
AT (1) AT374170B (en)
AU (1) AU532359B2 (en)
BE (1) BE885393A (en)
BR (1) BR8006042A (en)
CA (1) CA1128512A (en)
CH (1) CH646138A5 (en)
CS (1) CS227012B2 (en)
DE (1) DE3035688A1 (en)
DK (1) DK154136C (en)
EG (1) EG15020A (en)
ES (2) ES8200329A1 (en)
FI (1) FI72967C (en)
FR (1) FR2465710A1 (en)
GB (1) GB2059963B (en)
GR (1) GR70049B (en)
HK (1) HK59383A (en)
HU (1) HU183215B (en)
IE (1) IE50268B1 (en)
IL (1) IL60999A (en)
IN (3) IN151313B (en)
IT (1) IT1133823B (en)
KE (1) KE3307A (en)
LU (1) LU82797A1 (en)
MX (1) MX7159E (en)
NL (1) NL8005346A (en)
NO (1) NO152128C (en)
NZ (1) NZ195061A (en)
PH (1) PH22628A (en)
PL (1) PL128998B1 (en)
PT (1) PT71839B (en)
SE (1) SE448626B (en)
SG (1) SG42983G (en)
YU (3) YU41734B (en)
ZA (1) ZA805476B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
US6066671A (en) 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AR030345A1 (en) * 2000-08-14 2003-08-20 Alcon Inc METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS
MXPA04002009A (en) 2001-09-03 2004-07-08 Newron Pharm Spa Pharmaceutical composition comprising gabapentin or an analogue thereof and an $g(a)-aminoamide and its analgesic use.
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
CZ301776B6 (en) * 2009-06-08 2010-06-16 Farmak, A.S. Process for preparing 2-amino-3-benzoylphenylacetamide (nepafenac) with minimum by-products
CN112794809B (en) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 Preparation method of high-purity nepafenac intermediate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (en) * 1967-07-31 1971-03-24
CH577461A5 (en) * 1975-08-13 1976-07-15 Robins Co Inc A H
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ES495329A0 (en) 1981-10-16
CS227012B2 (en) 1984-04-16
YU245080A (en) 1983-09-30
FI803002A (en) 1981-03-27
IN156255B (en) 1985-06-08
IE50268B1 (en) 1986-03-19
YU43306B (en) 1989-06-30
KE3307A (en) 1983-08-19
IE801946L (en) 1981-03-26
IN156254B (en) 1985-06-08
PL226919A1 (en) 1982-02-01
NO152128B (en) 1985-04-29
KR840000763B1 (en) 1984-06-08
IT1133823B (en) 1986-07-24
BE885393A (en) 1981-01-16
IL60999A0 (en) 1980-11-30
YU73183A (en) 1983-12-31
MX7159E (en) 1987-12-02
NL8005346A (en) 1981-03-30
SG42983G (en) 1985-01-11
JPS5657751A (en) 1981-05-20
AU6211680A (en) 1981-04-02
DK405780A (en) 1981-03-27
PL128998B1 (en) 1984-03-31
NZ195061A (en) 1984-04-27
HU183215B (en) 1984-04-28
AU532359B2 (en) 1983-09-29
BR8006042A (en) 1981-04-07
JPH0141616B2 (en) 1989-09-06
NO152128C (en) 1985-08-07
FR2465710B1 (en) 1984-10-12
CH646138A5 (en) 1984-11-15
DE3035688C2 (en) 1990-05-17
LU82797A1 (en) 1982-05-10
PT71839A (en) 1980-10-01
FI72967B (en) 1987-04-30
NO802834L (en) 1981-03-27
IL60999A (en) 1984-05-31
IT8024948A0 (en) 1980-09-26
DE3035688A1 (en) 1981-04-16
GR70049B (en) 1982-07-26
ES8200329A1 (en) 1981-10-16
PT71839B (en) 1981-06-25
ZA805476B (en) 1981-11-25
ES503019A0 (en) 1982-05-01
HK59383A (en) 1983-12-02
SE448626B (en) 1987-03-09
ATA474580A (en) 1983-08-15
AT374170B (en) 1984-03-26
PH22628A (en) 1988-10-28
DK154136C (en) 1989-03-06
KR830004210A (en) 1983-07-06
FI72967C (en) 1987-08-10
ES8204715A1 (en) 1982-05-01
CA1128512A (en) 1982-07-27
DK154136B (en) 1988-10-17
GB2059963A (en) 1981-04-29
YU41734B (en) 1987-12-31
IN151313B (en) 1983-03-26
FR2465710A1 (en) 1981-03-27
EG15020A (en) 1985-03-31
GB2059963B (en) 1983-04-20
YU73083A (en) 1983-12-31
SE8006668L (en) 1981-03-27

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