IT1133823B - 2-AMINO-3-BENZOYLPHENYLACETAMIDES AND THEIR CYCLICAL APPROVALS PARTICULARLY USEFUL AS MEDICATIONS - Google Patents

2-AMINO-3-BENZOYLPHENYLACETAMIDES AND THEIR CYCLICAL APPROVALS PARTICULARLY USEFUL AS MEDICATIONS

Info

Publication number
IT1133823B
IT1133823B IT24948/80A IT2494880A IT1133823B IT 1133823 B IT1133823 B IT 1133823B IT 24948/80 A IT24948/80 A IT 24948/80A IT 2494880 A IT2494880 A IT 2494880A IT 1133823 B IT1133823 B IT 1133823B
Authority
IT
Italy
Prior art keywords
benzoylphenylacetamides
approvals
cyclical
medications
amino
Prior art date
Application number
IT24948/80A
Other languages
Italian (it)
Other versions
IT8024948A0 (en
Inventor
James Robert Shanklin
Dwight Allen Shamblee
David Allan Walsh
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of IT8024948A0 publication Critical patent/IT8024948A0/en
Application granted granted Critical
Publication of IT1133823B publication Critical patent/IT1133823B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT24948/80A 1979-09-26 1980-09-26 2-AMINO-3-BENZOYLPHENYLACETAMIDES AND THEIR CYCLICAL APPROVALS PARTICULARLY USEFUL AS MEDICATIONS IT1133823B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7886079A 1979-09-26 1979-09-26

Publications (2)

Publication Number Publication Date
IT8024948A0 IT8024948A0 (en) 1980-09-26
IT1133823B true IT1133823B (en) 1986-07-24

Family

ID=22146633

Family Applications (1)

Application Number Title Priority Date Filing Date
IT24948/80A IT1133823B (en) 1979-09-26 1980-09-26 2-AMINO-3-BENZOYLPHENYLACETAMIDES AND THEIR CYCLICAL APPROVALS PARTICULARLY USEFUL AS MEDICATIONS

Country Status (36)

Country Link
JP (1) JPS5657751A (en)
KR (1) KR840000763B1 (en)
AT (1) AT374170B (en)
AU (1) AU532359B2 (en)
BE (1) BE885393A (en)
BR (1) BR8006042A (en)
CA (1) CA1128512A (en)
CH (1) CH646138A5 (en)
CS (1) CS227012B2 (en)
DE (1) DE3035688A1 (en)
DK (1) DK154136C (en)
EG (1) EG15020A (en)
ES (2) ES495329A0 (en)
FI (1) FI72967C (en)
FR (1) FR2465710A1 (en)
GB (1) GB2059963B (en)
GR (1) GR70049B (en)
HK (1) HK59383A (en)
HU (1) HU183215B (en)
IE (1) IE50268B1 (en)
IL (1) IL60999A (en)
IN (3) IN151313B (en)
IT (1) IT1133823B (en)
KE (1) KE3307A (en)
LU (1) LU82797A1 (en)
MX (1) MX7159E (en)
NL (1) NL8005346A (en)
NO (1) NO152128C (en)
NZ (1) NZ195061A (en)
PH (1) PH22628A (en)
PL (1) PL128998B1 (en)
PT (1) PT71839B (en)
SE (1) SE448626B (en)
SG (1) SG42983G (en)
YU (3) YU41734B (en)
ZA (1) ZA805476B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
US6066671A (en) * 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AR030345A1 (en) * 2000-08-14 2003-08-20 Alcon Inc METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS
PT1423168E (en) 2001-09-03 2006-05-31 Newron Pharm Spa PHARMACEUTICAL COMPOSITION WHICH UNDERSTAND GABAPENTINE OR ITS ANALOGUE AND AN X-AMINOAMIDE AND ITS USE AS ANALGESIC
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
CZ301776B6 (en) * 2009-06-08 2010-06-16 Farmak, A.S. Process for preparing 2-amino-3-benzoylphenylacetamide (nepafenac) with minimum by-products
CN112794809B (en) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 Preparation method of high-purity nepafenac intermediate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (en) * 1967-07-31 1971-03-24
SE400966B (en) * 1975-08-13 1978-04-17 Robins Co Inc A H PROCEDURE FOR PREPARING 2-AMINO-3- (OR 5-) BENZOYL-PHENYLETIC ACIDS
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ZA805476B (en) 1981-11-25
FI72967B (en) 1987-04-30
PL128998B1 (en) 1984-03-31
KR840000763B1 (en) 1984-06-08
NL8005346A (en) 1981-03-30
NZ195061A (en) 1984-04-27
NO152128C (en) 1985-08-07
IE50268B1 (en) 1986-03-19
YU73083A (en) 1983-12-31
DK154136C (en) 1989-03-06
HK59383A (en) 1983-12-02
IT8024948A0 (en) 1980-09-26
PH22628A (en) 1988-10-28
CA1128512A (en) 1982-07-27
CH646138A5 (en) 1984-11-15
AT374170B (en) 1984-03-26
SG42983G (en) 1985-01-11
EG15020A (en) 1985-03-31
NO152128B (en) 1985-04-29
ES8204715A1 (en) 1982-05-01
LU82797A1 (en) 1982-05-10
DK405780A (en) 1981-03-27
FI72967C (en) 1987-08-10
GB2059963B (en) 1983-04-20
GR70049B (en) 1982-07-26
YU73183A (en) 1983-12-31
IL60999A (en) 1984-05-31
YU41734B (en) 1987-12-31
FR2465710B1 (en) 1984-10-12
IN151313B (en) 1983-03-26
SE8006668L (en) 1981-03-27
CS227012B2 (en) 1984-04-16
GB2059963A (en) 1981-04-29
AU532359B2 (en) 1983-09-29
ES503019A0 (en) 1982-05-01
YU245080A (en) 1983-09-30
MX7159E (en) 1987-12-02
YU43306B (en) 1989-06-30
BE885393A (en) 1981-01-16
IE801946L (en) 1981-03-26
DE3035688C2 (en) 1990-05-17
PT71839A (en) 1980-10-01
ES8200329A1 (en) 1981-10-16
SE448626B (en) 1987-03-09
NO802834L (en) 1981-03-27
ATA474580A (en) 1983-08-15
DE3035688A1 (en) 1981-04-16
HU183215B (en) 1984-04-28
FI803002A (en) 1981-03-27
AU6211680A (en) 1981-04-02
PT71839B (en) 1981-06-25
PL226919A1 (en) 1982-02-01
IN156255B (en) 1985-06-08
JPS5657751A (en) 1981-05-20
ES495329A0 (en) 1981-10-16
KE3307A (en) 1983-08-19
DK154136B (en) 1988-10-17
BR8006042A (en) 1981-04-07
KR830004210A (en) 1983-07-06
IL60999A0 (en) 1980-11-30
IN156254B (en) 1985-06-08
FR2465710A1 (en) 1981-03-27
JPH0141616B2 (en) 1989-09-06
YU43305B (en) 1989-06-30

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