ATA474580A - METHOD FOR PRODUCING NEW 2-AMINO-3 -BENZOYL-PHENYL ACETAMIDE DERIVATIVES - Google Patents

METHOD FOR PRODUCING NEW 2-AMINO-3 -BENZOYL-PHENYL ACETAMIDE DERIVATIVES

Info

Publication number
ATA474580A
ATA474580A AT0474580A AT474580A ATA474580A AT A474580 A ATA474580 A AT A474580A AT 0474580 A AT0474580 A AT 0474580A AT 474580 A AT474580 A AT 474580A AT A474580 A ATA474580 A AT A474580A
Authority
AT
Austria
Prior art keywords
benzoyl
amino
producing new
phenyl acetamide
acetamide derivatives
Prior art date
Application number
AT0474580A
Other languages
German (de)
Other versions
AT374170B (en
Inventor
J R Shanklin
D A Shamblee
D A Walsh
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Priority to AT538481A priority Critical patent/AT379740B/en
Publication of ATA474580A publication Critical patent/ATA474580A/en
Application granted granted Critical
Publication of AT374170B publication Critical patent/AT374170B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
AT0474580A 1979-09-26 1980-09-23 METHOD FOR PRODUCING NEW 2-AMINO-3 -BENZOYL-PHENYL ACETAMIDE DERIVATIVES AT374170B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT538481A AT379740B (en) 1979-09-26 1981-12-16 METHOD FOR REDUCING INFLAMMATION AND PAIN OR FOR INHIBITING THE THROMBOZYTE AGGREGATION IN A LIVING ANIMAL BODY

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7886079A 1979-09-26 1979-09-26

Publications (2)

Publication Number Publication Date
ATA474580A true ATA474580A (en) 1983-08-15
AT374170B AT374170B (en) 1984-03-26

Family

ID=22146633

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0474580A AT374170B (en) 1979-09-26 1980-09-23 METHOD FOR PRODUCING NEW 2-AMINO-3 -BENZOYL-PHENYL ACETAMIDE DERIVATIVES

Country Status (36)

Country Link
JP (1) JPS5657751A (en)
KR (1) KR840000763B1 (en)
AT (1) AT374170B (en)
AU (1) AU532359B2 (en)
BE (1) BE885393A (en)
BR (1) BR8006042A (en)
CA (1) CA1128512A (en)
CH (1) CH646138A5 (en)
CS (1) CS227012B2 (en)
DE (1) DE3035688A1 (en)
DK (1) DK154136C (en)
EG (1) EG15020A (en)
ES (2) ES8200329A1 (en)
FI (1) FI72967C (en)
FR (1) FR2465710A1 (en)
GB (1) GB2059963B (en)
GR (1) GR70049B (en)
HK (1) HK59383A (en)
HU (1) HU183215B (en)
IE (1) IE50268B1 (en)
IL (1) IL60999A (en)
IN (3) IN151313B (en)
IT (1) IT1133823B (en)
KE (1) KE3307A (en)
LU (1) LU82797A1 (en)
MX (1) MX7159E (en)
NL (1) NL8005346A (en)
NO (1) NO152128C (en)
NZ (1) NZ195061A (en)
PH (1) PH22628A (en)
PL (1) PL128998B1 (en)
PT (1) PT71839B (en)
SE (1) SE448626B (en)
SG (1) SG42983G (en)
YU (3) YU41734B (en)
ZA (1) ZA805476B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
US6066671A (en) * 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AR030345A1 (en) * 2000-08-14 2003-08-20 Alcon Inc METHOD OF TREATMENT OF DISORDERS RELATED TO ANGIOGENESIS
IL160523A0 (en) 2001-09-03 2004-07-25 Newron Pharm Spa PHARMACEUTICAL COMPOSITION COMPRISING GABAPENTIN OR AN ANALOGUE THEREOF AND AN alpha-AMINOAMIDE AND ITS ANALGESIC USE
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
CZ2009367A3 (en) * 2009-06-08 2010-06-16 Farmak, A.S. Process for preparing 2-amino-3-benzoylphenylacetamide (nepafenac) with minimum of by-products
CN112794809B (en) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 Preparation method of high-purity nepafenac intermediate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (en) * 1967-07-31 1971-03-24
CH577461A5 (en) * 1975-08-13 1976-07-15 Robins Co Inc A H
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EG15020A (en) 1985-03-31
FR2465710B1 (en) 1984-10-12
KE3307A (en) 1983-08-19
JPS5657751A (en) 1981-05-20
FI803002A (en) 1981-03-27
IL60999A0 (en) 1980-11-30
LU82797A1 (en) 1982-05-10
GB2059963A (en) 1981-04-29
AU6211680A (en) 1981-04-02
PL128998B1 (en) 1984-03-31
AU532359B2 (en) 1983-09-29
BR8006042A (en) 1981-04-07
NZ195061A (en) 1984-04-27
YU73183A (en) 1983-12-31
SG42983G (en) 1985-01-11
PT71839A (en) 1980-10-01
FI72967C (en) 1987-08-10
KR840000763B1 (en) 1984-06-08
DE3035688A1 (en) 1981-04-16
CH646138A5 (en) 1984-11-15
IN156255B (en) 1985-06-08
ES495329A0 (en) 1981-10-16
GR70049B (en) 1982-07-26
IT8024948A0 (en) 1980-09-26
FR2465710A1 (en) 1981-03-27
NO152128C (en) 1985-08-07
HU183215B (en) 1984-04-28
ZA805476B (en) 1981-11-25
MX7159E (en) 1987-12-02
DK154136B (en) 1988-10-17
IL60999A (en) 1984-05-31
IN151313B (en) 1983-03-26
FI72967B (en) 1987-04-30
AT374170B (en) 1984-03-26
DK154136C (en) 1989-03-06
ES8200329A1 (en) 1981-10-16
CS227012B2 (en) 1984-04-16
JPH0141616B2 (en) 1989-09-06
YU43305B (en) 1989-06-30
NL8005346A (en) 1981-03-30
SE448626B (en) 1987-03-09
DE3035688C2 (en) 1990-05-17
KR830004210A (en) 1983-07-06
DK405780A (en) 1981-03-27
NO152128B (en) 1985-04-29
PT71839B (en) 1981-06-25
YU73083A (en) 1983-12-31
SE8006668L (en) 1981-03-27
IN156254B (en) 1985-06-08
YU41734B (en) 1987-12-31
ES503019A0 (en) 1982-05-01
HK59383A (en) 1983-12-02
IT1133823B (en) 1986-07-24
CA1128512A (en) 1982-07-27
GB2059963B (en) 1983-04-20
YU245080A (en) 1983-09-30
ES8204715A1 (en) 1982-05-01
IE801946L (en) 1981-03-26
PL226919A1 (en) 1982-02-01
IE50268B1 (en) 1986-03-19
YU43306B (en) 1989-06-30
PH22628A (en) 1988-10-28
NO802834L (en) 1981-03-27
BE885393A (en) 1981-01-16

Similar Documents

Publication Publication Date Title
AT381302B (en) METHOD FOR PRODUCING NEW GLYCINAMIDE DERIVATIVES
ATA10882A (en) METHOD FOR PRODUCING NEW 6BETAHYDROXYALKYLPENICILLANSAEE DERIVATIVES
AT380259B (en) METHOD FOR PRODUCING NEW PEPTIDAMIDES
AT375078B (en) METHOD FOR PRODUCING NEW INDOLICINE DERIVATIVES
AT368509B (en) METHOD FOR PRODUCING NEW 3-VINYLCEPHALOSPORINES
AT369375B (en) METHOD FOR PRODUCING NEW 3-VINYLCEPHALOSPORINE DERIVATIVES
AT371816B (en) METHOD FOR PRODUCING NEW ISOCYANURS [UREDERIVATIVES
AT374170B (en) METHOD FOR PRODUCING NEW 2-AMINO-3 -BENZOYL-PHENYL ACETAMIDE DERIVATIVES
AT373259B (en) METHOD FOR PRODUCING NEW 1OXADETHIACEPHALOSPORINE DERIVATIVES
AT380255B (en) METHOD FOR PRODUCING NEW BENZO-AS-TRIAZINE DERIVATIVES
AT368511B (en) METHOD FOR PRODUCING NEW CEPHALOSPORINANTIBIOTICS
AT373595B (en) METHOD FOR PRODUCING NEW CHINAZOLINES
AT374798B (en) METHOD FOR PRODUCING NEW AMINOISOCHINOLINE DERIVATIVES
AT370725B (en) METHOD FOR PRODUCING NEW 16-METHOXY-16-METHYL-PROSTAGLANDIN-E1 DERIVATIVES
AT372077B (en) METHOD FOR PRODUCING NEW BENZYLIDE DERIVATIVES
AT372947B (en) METHOD FOR PRODUCING NEW TRANS-6OXODECAHYDROCHINOLINES
AT374481B (en) METHOD FOR PRODUCING NEW 3-THIOVINYLCEPHALOSPORINE DERIVATIVES
AT375648B (en) METHOD FOR PRODUCING NEW CARBOSTYRILE DERIVATIVES
AT374167B (en) METHOD FOR PRODUCING NEW NAPHTHACEN DERIVATIVES
AT374480B (en) METHOD FOR PRODUCING NEW 3-THIOVINYLCEPHALOSPORINE DERIVATIVES
AT369378B (en) METHOD FOR PRODUCING NEW 3-THIOVINYL-CEPHALOSPORINE DERIVATIVES
AT378534B (en) METHOD FOR PRODUCING NEW ERGOPEPTIN DERIVATIVES
ATA246483A (en) METHOD FOR PRODUCING NEW CARBOSTYRILE DERIVATIVES
ATA451583A (en) METHOD FOR PRODUCING NEW 1-PHENAETHYLIMIDAZOLE DERIVATIVES
ATA365181A (en) METHOD FOR PRODUCING NEW ACYLAMINOBENZOESAE DERIVATIVES

Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee