JPS5657751A - 22aminoo33benzoylphenylacet amide and cyclic homologue compound - Google Patents

22aminoo33benzoylphenylacet amide and cyclic homologue compound

Info

Publication number
JPS5657751A
JPS5657751A JP13415280A JP13415280A JPS5657751A JP S5657751 A JPS5657751 A JP S5657751A JP 13415280 A JP13415280 A JP 13415280A JP 13415280 A JP13415280 A JP 13415280A JP S5657751 A JPS5657751 A JP S5657751A
Authority
JP
Japan
Prior art keywords
amide
cyclic
compound
homologue compound
cyclic homologue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13415280A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0141616B2 (da
Inventor
Robaato Shiyankurin J Jieemusu
Aren Shiyanburii Dowaito
Aran Uorushiyu Deebitsudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AH Robins Co Inc
Original Assignee
AH Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AH Robins Co Inc filed Critical AH Robins Co Inc
Publication of JPS5657751A publication Critical patent/JPS5657751A/ja
Publication of JPH0141616B2 publication Critical patent/JPH0141616B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
JP13415280A 1979-09-26 1980-09-26 22aminoo33benzoylphenylacet amide and cyclic homologue compound Granted JPS5657751A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7886079A 1979-09-26 1979-09-26

Publications (2)

Publication Number Publication Date
JPS5657751A true JPS5657751A (en) 1981-05-20
JPH0141616B2 JPH0141616B2 (da) 1989-09-06

Family

ID=22146633

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13415280A Granted JPS5657751A (en) 1979-09-26 1980-09-26 22aminoo33benzoylphenylacet amide and cyclic homologue compound

Country Status (36)

Country Link
JP (1) JPS5657751A (da)
KR (1) KR840000763B1 (da)
AT (1) AT374170B (da)
AU (1) AU532359B2 (da)
BE (1) BE885393A (da)
BR (1) BR8006042A (da)
CA (1) CA1128512A (da)
CH (1) CH646138A5 (da)
CS (1) CS227012B2 (da)
DE (1) DE3035688A1 (da)
DK (1) DK154136C (da)
EG (1) EG15020A (da)
ES (2) ES8200329A1 (da)
FI (1) FI72967C (da)
FR (1) FR2465710A1 (da)
GB (1) GB2059963B (da)
GR (1) GR70049B (da)
HK (1) HK59383A (da)
HU (1) HU183215B (da)
IE (1) IE50268B1 (da)
IL (1) IL60999A (da)
IN (3) IN151313B (da)
IT (1) IT1133823B (da)
KE (1) KE3307A (da)
LU (1) LU82797A1 (da)
MX (1) MX7159E (da)
NL (1) NL8005346A (da)
NO (1) NO152128C (da)
NZ (1) NZ195061A (da)
PH (1) PH22628A (da)
PL (1) PL128998B1 (da)
PT (1) PT71839B (da)
SE (1) SE448626B (da)
SG (1) SG42983G (da)
YU (3) YU41734B (da)
ZA (1) ZA805476B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
US6066671A (en) 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
EP1423168B1 (en) 2001-09-03 2006-02-08 Newron Pharmaceuticals S.p.A. Pharmaceutical composition comprising gabapentin or an analogue thereof and an alpha-aminoamide and its analgesic use
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
CZ301776B6 (cs) * 2009-06-08 2010-06-16 Farmak, A.S. Postup prípravy 2-amino-3-benzoylfenylacetamidu (nepafenacu) s minimem vedlejších produktu
CN112794809B (zh) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 一种高纯度奈帕芬胺中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (da) * 1967-07-31 1971-03-24
SE400966B (sv) * 1975-08-13 1978-04-17 Robins Co Inc A H Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ES495329A0 (es) 1981-10-16
HU183215B (en) 1984-04-28
CA1128512A (en) 1982-07-27
KR840000763B1 (ko) 1984-06-08
LU82797A1 (fr) 1982-05-10
BR8006042A (pt) 1981-04-07
ES8200329A1 (es) 1981-10-16
IT1133823B (it) 1986-07-24
PT71839B (en) 1981-06-25
ES503019A0 (es) 1982-05-01
HK59383A (en) 1983-12-02
FR2465710B1 (da) 1984-10-12
IE801946L (en) 1981-03-26
CH646138A5 (fr) 1984-11-15
KE3307A (en) 1983-08-19
NL8005346A (nl) 1981-03-30
ES8204715A1 (es) 1982-05-01
AU532359B2 (en) 1983-09-29
NZ195061A (en) 1984-04-27
AT374170B (de) 1984-03-26
YU41734B (en) 1987-12-31
NO802834L (no) 1981-03-27
ATA474580A (de) 1983-08-15
DE3035688C2 (da) 1990-05-17
YU245080A (en) 1983-09-30
IE50268B1 (en) 1986-03-19
FI72967C (fi) 1987-08-10
PH22628A (en) 1988-10-28
GB2059963A (en) 1981-04-29
SE448626B (sv) 1987-03-09
DE3035688A1 (de) 1981-04-16
CS227012B2 (en) 1984-04-16
IL60999A0 (en) 1980-11-30
IT8024948A0 (it) 1980-09-26
KR830004210A (ko) 1983-07-06
YU43306B (en) 1989-06-30
SE8006668L (sv) 1981-03-27
YU73183A (en) 1983-12-31
FI803002A (fi) 1981-03-27
JPH0141616B2 (da) 1989-09-06
IN156254B (da) 1985-06-08
YU73083A (en) 1983-12-31
AU6211680A (en) 1981-04-02
EG15020A (en) 1985-03-31
SG42983G (en) 1985-01-11
DK154136B (da) 1988-10-17
PL128998B1 (en) 1984-03-31
NO152128B (no) 1985-04-29
IN151313B (da) 1983-03-26
FR2465710A1 (fr) 1981-03-27
ZA805476B (en) 1981-11-25
DK405780A (da) 1981-03-27
DK154136C (da) 1989-03-06
YU43305B (en) 1989-06-30
GR70049B (da) 1982-07-26
PT71839A (en) 1980-10-01
FI72967B (fi) 1987-04-30
IL60999A (en) 1984-05-31
BE885393A (fr) 1981-01-16
NO152128C (no) 1985-08-07
GB2059963B (en) 1983-04-20
MX7159E (es) 1987-12-02
PL226919A1 (da) 1982-02-01
IN156255B (da) 1985-06-08

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