AT374170B - Verfahren zur herstellung von neuen 2-amino-3 -benzoyl-phenylacetamid-derivaten - Google Patents

Verfahren zur herstellung von neuen 2-amino-3 -benzoyl-phenylacetamid-derivaten

Info

Publication number
AT374170B
AT374170B AT0474580A AT474580A AT374170B AT 374170 B AT374170 B AT 374170B AT 0474580 A AT0474580 A AT 0474580A AT 474580 A AT474580 A AT 474580A AT 374170 B AT374170 B AT 374170B
Authority
AT
Austria
Prior art keywords
benzoyl
amino
producing new
phenyl acetamide
acetamide derivatives
Prior art date
Application number
AT0474580A
Other languages
German (de)
English (en)
Other versions
ATA474580A (de
Inventor
J R Shanklin
D A Shamblee
D A Walsh
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Priority to AT538481A priority Critical patent/AT379740B/de
Publication of ATA474580A publication Critical patent/ATA474580A/de
Application granted granted Critical
Publication of AT374170B publication Critical patent/AT374170B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT0474580A 1979-09-26 1980-09-23 Verfahren zur herstellung von neuen 2-amino-3 -benzoyl-phenylacetamid-derivaten AT374170B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT538481A AT379740B (de) 1979-09-26 1981-12-16 Verfahren zur linderung von entzuendungen und schmerzen bzw. zur inhibierung der thrombozyten-aggregation in einem lebenden tierkoerper

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7886079A 1979-09-26 1979-09-26

Publications (2)

Publication Number Publication Date
ATA474580A ATA474580A (de) 1983-08-15
AT374170B true AT374170B (de) 1984-03-26

Family

ID=22146633

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0474580A AT374170B (de) 1979-09-26 1980-09-23 Verfahren zur herstellung von neuen 2-amino-3 -benzoyl-phenylacetamid-derivaten

Country Status (36)

Country Link
JP (1) JPS5657751A (ja)
KR (1) KR840000763B1 (ja)
AT (1) AT374170B (ja)
AU (1) AU532359B2 (ja)
BE (1) BE885393A (ja)
BR (1) BR8006042A (ja)
CA (1) CA1128512A (ja)
CH (1) CH646138A5 (ja)
CS (1) CS227012B2 (ja)
DE (1) DE3035688A1 (ja)
DK (1) DK154136C (ja)
EG (1) EG15020A (ja)
ES (2) ES495329A0 (ja)
FI (1) FI72967C (ja)
FR (1) FR2465710A1 (ja)
GB (1) GB2059963B (ja)
GR (1) GR70049B (ja)
HK (1) HK59383A (ja)
HU (1) HU183215B (ja)
IE (1) IE50268B1 (ja)
IL (1) IL60999A (ja)
IN (3) IN151313B (ja)
IT (1) IT1133823B (ja)
KE (1) KE3307A (ja)
LU (1) LU82797A1 (ja)
MX (1) MX7159E (ja)
NL (1) NL8005346A (ja)
NO (1) NO152128C (ja)
NZ (1) NZ195061A (ja)
PH (1) PH22628A (ja)
PL (1) PL128998B1 (ja)
PT (1) PT71839B (ja)
SE (1) SE448626B (ja)
SG (1) SG42983G (ja)
YU (3) YU41734B (ja)
ZA (1) ZA805476B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
US6066671A (en) * 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
PT1423168E (pt) 2001-09-03 2006-05-31 Newron Pharm Spa Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
CZ2009367A3 (cs) * 2009-06-08 2010-06-16 Farmak, A.S. Postup prípravy 2-amino-3-benzoylfenylacetamidu (nepafenacu) s minimem vedlejších produktu
CN112794809B (zh) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 一种高纯度奈帕芬胺中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (ja) * 1967-07-31 1971-03-24
SE400966B (sv) * 1975-08-13 1978-04-17 Robins Co Inc A H Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
GR70049B (ja) 1982-07-26
KE3307A (en) 1983-08-19
DK154136B (da) 1988-10-17
ES8200329A1 (es) 1981-10-16
HU183215B (en) 1984-04-28
DK405780A (da) 1981-03-27
FR2465710B1 (ja) 1984-10-12
IL60999A (en) 1984-05-31
YU43306B (en) 1989-06-30
IE801946L (en) 1981-03-26
YU73183A (en) 1983-12-31
JPS5657751A (en) 1981-05-20
NZ195061A (en) 1984-04-27
JPH0141616B2 (ja) 1989-09-06
LU82797A1 (fr) 1982-05-10
BR8006042A (pt) 1981-04-07
ES8204715A1 (es) 1982-05-01
FI72967B (fi) 1987-04-30
IN151313B (ja) 1983-03-26
NL8005346A (nl) 1981-03-30
KR840000763B1 (ko) 1984-06-08
CH646138A5 (fr) 1984-11-15
NO152128B (no) 1985-04-29
FI72967C (fi) 1987-08-10
IL60999A0 (en) 1980-11-30
AU6211680A (en) 1981-04-02
YU41734B (en) 1987-12-31
ES503019A0 (es) 1982-05-01
HK59383A (en) 1983-12-02
AU532359B2 (en) 1983-09-29
NO152128C (no) 1985-08-07
PL128998B1 (en) 1984-03-31
GB2059963A (en) 1981-04-29
YU245080A (en) 1983-09-30
IT1133823B (it) 1986-07-24
FR2465710A1 (fr) 1981-03-27
EG15020A (en) 1985-03-31
YU73083A (en) 1983-12-31
IE50268B1 (en) 1986-03-19
DE3035688A1 (de) 1981-04-16
DK154136C (da) 1989-03-06
GB2059963B (en) 1983-04-20
SE8006668L (sv) 1981-03-27
YU43305B (en) 1989-06-30
MX7159E (es) 1987-12-02
ES495329A0 (es) 1981-10-16
FI803002A (fi) 1981-03-27
SG42983G (en) 1985-01-11
IN156254B (ja) 1985-06-08
IT8024948A0 (it) 1980-09-26
KR830004210A (ko) 1983-07-06
NO802834L (no) 1981-03-27
BE885393A (fr) 1981-01-16
PH22628A (en) 1988-10-28
PL226919A1 (ja) 1982-02-01
IN156255B (ja) 1985-06-08
PT71839B (en) 1981-06-25
PT71839A (en) 1980-10-01
DE3035688C2 (ja) 1990-05-17
CS227012B2 (en) 1984-04-16
ATA474580A (de) 1983-08-15
CA1128512A (en) 1982-07-27
SE448626B (sv) 1987-03-09
ZA805476B (en) 1981-11-25

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee