NL8005346A - 2-amino-3-benzoyl-fenylaceetamiden en cyclische homologen. - Google Patents

2-amino-3-benzoyl-fenylaceetamiden en cyclische homologen. Download PDF

Info

Publication number
NL8005346A
NL8005346A NL8005346A NL8005346A NL8005346A NL 8005346 A NL8005346 A NL 8005346A NL 8005346 A NL8005346 A NL 8005346A NL 8005346 A NL8005346 A NL 8005346A NL 8005346 A NL8005346 A NL 8005346A
Authority
NL
Netherlands
Prior art keywords
amino
compound
benzoyl
phenylacetamide
administered
Prior art date
Application number
NL8005346A
Other languages
English (en)
Dutch (nl)
Inventor
J R Shanklin
D A Shamblee
D A Walsh
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of NL8005346A publication Critical patent/NL8005346A/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL8005346A 1979-09-26 1980-09-25 2-amino-3-benzoyl-fenylaceetamiden en cyclische homologen. NL8005346A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7886079A 1979-09-26 1979-09-26
US7886079 1979-09-26

Publications (1)

Publication Number Publication Date
NL8005346A true NL8005346A (nl) 1981-03-30

Family

ID=22146633

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8005346A NL8005346A (nl) 1979-09-26 1980-09-25 2-amino-3-benzoyl-fenylaceetamiden en cyclische homologen.

Country Status (36)

Country Link
JP (1) JPS5657751A (ja)
KR (1) KR840000763B1 (ja)
AT (1) AT374170B (ja)
AU (1) AU532359B2 (ja)
BE (1) BE885393A (ja)
BR (1) BR8006042A (ja)
CA (1) CA1128512A (ja)
CH (1) CH646138A5 (ja)
CS (1) CS227012B2 (ja)
DE (1) DE3035688A1 (ja)
DK (1) DK154136C (ja)
EG (1) EG15020A (ja)
ES (2) ES495329A0 (ja)
FI (1) FI72967C (ja)
FR (1) FR2465710A1 (ja)
GB (1) GB2059963B (ja)
GR (1) GR70049B (ja)
HK (1) HK59383A (ja)
HU (1) HU183215B (ja)
IE (1) IE50268B1 (ja)
IL (1) IL60999A (ja)
IN (3) IN151313B (ja)
IT (1) IT1133823B (ja)
KE (1) KE3307A (ja)
LU (1) LU82797A1 (ja)
MX (1) MX7159E (ja)
NL (1) NL8005346A (ja)
NO (1) NO152128C (ja)
NZ (1) NZ195061A (ja)
PH (1) PH22628A (ja)
PL (1) PL128998B1 (ja)
PT (1) PT71839B (ja)
SE (1) SE448626B (ja)
SG (1) SG42983G (ja)
YU (3) YU41734B (ja)
ZA (1) ZA805476B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
US6066671A (en) * 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
PT1423168E (pt) 2001-09-03 2006-05-31 Newron Pharm Spa Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
CZ2009367A3 (cs) * 2009-06-08 2010-06-16 Farmak, A.S. Postup prípravy 2-amino-3-benzoylfenylacetamidu (nepafenacu) s minimem vedlejších produktu
CN112794809B (zh) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 一种高纯度奈帕芬胺中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (ja) * 1967-07-31 1971-03-24
SE400966B (sv) * 1975-08-13 1978-04-17 Robins Co Inc A H Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
GR70049B (ja) 1982-07-26
KE3307A (en) 1983-08-19
DK154136B (da) 1988-10-17
ES8200329A1 (es) 1981-10-16
HU183215B (en) 1984-04-28
DK405780A (da) 1981-03-27
FR2465710B1 (ja) 1984-10-12
IL60999A (en) 1984-05-31
YU43306B (en) 1989-06-30
IE801946L (en) 1981-03-26
YU73183A (en) 1983-12-31
JPS5657751A (en) 1981-05-20
NZ195061A (en) 1984-04-27
JPH0141616B2 (ja) 1989-09-06
LU82797A1 (fr) 1982-05-10
BR8006042A (pt) 1981-04-07
ES8204715A1 (es) 1982-05-01
FI72967B (fi) 1987-04-30
IN151313B (ja) 1983-03-26
KR840000763B1 (ko) 1984-06-08
CH646138A5 (fr) 1984-11-15
NO152128B (no) 1985-04-29
FI72967C (fi) 1987-08-10
IL60999A0 (en) 1980-11-30
AU6211680A (en) 1981-04-02
YU41734B (en) 1987-12-31
ES503019A0 (es) 1982-05-01
HK59383A (en) 1983-12-02
AU532359B2 (en) 1983-09-29
NO152128C (no) 1985-08-07
PL128998B1 (en) 1984-03-31
GB2059963A (en) 1981-04-29
YU245080A (en) 1983-09-30
IT1133823B (it) 1986-07-24
FR2465710A1 (fr) 1981-03-27
EG15020A (en) 1985-03-31
YU73083A (en) 1983-12-31
IE50268B1 (en) 1986-03-19
DE3035688A1 (de) 1981-04-16
DK154136C (da) 1989-03-06
GB2059963B (en) 1983-04-20
SE8006668L (sv) 1981-03-27
YU43305B (en) 1989-06-30
MX7159E (es) 1987-12-02
ES495329A0 (es) 1981-10-16
FI803002A (fi) 1981-03-27
SG42983G (en) 1985-01-11
IN156254B (ja) 1985-06-08
IT8024948A0 (it) 1980-09-26
AT374170B (de) 1984-03-26
KR830004210A (ko) 1983-07-06
NO802834L (no) 1981-03-27
BE885393A (fr) 1981-01-16
PH22628A (en) 1988-10-28
PL226919A1 (ja) 1982-02-01
IN156255B (ja) 1985-06-08
PT71839B (en) 1981-06-25
PT71839A (en) 1980-10-01
DE3035688C2 (ja) 1990-05-17
CS227012B2 (en) 1984-04-16
ATA474580A (de) 1983-08-15
CA1128512A (en) 1982-07-27
SE448626B (sv) 1987-03-09
ZA805476B (en) 1981-11-25

Similar Documents

Publication Publication Date Title
RU2208010C2 (ru) Фармацевтическая композиция (варианты), производные 3,5-дифенил-1,2,4-триазолов, в нее входящие
US4313949A (en) Method of producing an inhibitory effect on blood platelet aggregation
JPH02117664A (ja) 4‐ピリドン‐3‐カルボン酸およびその誘導体
PL154186B1 (en) Method for manufacturing arylic derivatives of the hydroxamic acid
NL8005346A (nl) 2-amino-3-benzoyl-fenylaceetamiden en cyclische homologen.
US4375479A (en) Indanyl derivatives and use
JPS6157306B2 (ja)
HU199440B (en) Process for producing morpholine derivatives and pharmaceutical compositions comprising the compounds
JPH0222059B2 (ja)
KR100979077B1 (ko) 벤즈아제핀 화합물의 고체 염 및 이를 포함하는 약제학적 조성물
JPH0153266B2 (ja)
JPH01106839A (ja) アルカジエン誘導体類、それらの製造、およびそれらを含有している薬学的組成物
EP0475214B1 (en) Caffeic acid derivatives and pharmaceutical compositions containing the same
US4521619A (en) Therapeutically useful sulphur-containing benzylidene derivatives
JP2584336B2 (ja) カルボン酸アミド誘導体
JPH01104064A (ja) 塩基性に置換されたベンゾフランカルボン酸アミド、この化合物の製法及びこれを含有する医薬
HUT75341A (en) New salts of 2-[(2,6-dichloro-phenyl)-amino]-phenyl-acetoxy-acetic acid with organic bases, pharmaceutical compns. contg. them and process for preparing the said compds.
FR2465733A1 (fr) Nouveaux derives imidazolylethoxymethyliques de 1,3-dioxoloquinoleines utiles notamment comme medicaments antibacteriens et antifongiques, leur procede de preparation et compositions therapeutiques et formes pharmaceutiques les contenant
WO2022022373A1 (zh) 苯并吡喃衍生物及其在制备治疗类风湿性关节炎的药物中的应用
CS221527B2 (en) Method of preparation of n-/1-methyl-2-pyrrolidinylmethyl/2,3-dimethoxy-5-methylsulphamoylbenzamide
US3821415A (en) Heterocyclic compounds in pharmaceutical compositions and methods
EP0260924A1 (en) Antiinflammatory derivatives of 3-aryl-2,1-benzisoxazole
JPH01149776A (ja) トリアゾリルアルカノール
JP3038032B2 (ja) 血小板凝集抑制薬
JPS6310785A (ja) 新規1,2−ジチオ−ル−3−チオン誘導体、その製造方法およびそれを有効成分とする免疫調節剤

Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed