EG15020A - Process for preparing 2-amino-3-benzoyl-phenylacetamides and cyclic homologues - Google Patents

Process for preparing 2-amino-3-benzoyl-phenylacetamides and cyclic homologues

Info

Publication number
EG15020A
EG15020A EG80573A EG57380A EG15020A EG 15020 A EG15020 A EG 15020A EG 80573 A EG80573 A EG 80573A EG 57380 A EG57380 A EG 57380A EG 15020 A EG15020 A EG 15020A
Authority
EG
Egypt
Prior art keywords
phenylacetamides
benzoyl
amino
preparing
cyclic homologues
Prior art date
Application number
EG80573A
Other languages
English (en)
Inventor
R Shanklin James
A Walsh David
A Shamblee Dwight
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Application granted granted Critical
Publication of EG15020A publication Critical patent/EG15020A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EG80573A 1979-09-26 1980-09-20 Process for preparing 2-amino-3-benzoyl-phenylacetamides and cyclic homologues EG15020A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7886079A 1979-09-26 1979-09-26

Publications (1)

Publication Number Publication Date
EG15020A true EG15020A (en) 1985-03-31

Family

ID=22146633

Family Applications (1)

Application Number Title Priority Date Filing Date
EG80573A EG15020A (en) 1979-09-26 1980-09-20 Process for preparing 2-amino-3-benzoyl-phenylacetamides and cyclic homologues

Country Status (36)

Country Link
JP (1) JPS5657751A (ja)
KR (1) KR840000763B1 (ja)
AT (1) AT374170B (ja)
AU (1) AU532359B2 (ja)
BE (1) BE885393A (ja)
BR (1) BR8006042A (ja)
CA (1) CA1128512A (ja)
CH (1) CH646138A5 (ja)
CS (1) CS227012B2 (ja)
DE (1) DE3035688A1 (ja)
DK (1) DK154136C (ja)
EG (1) EG15020A (ja)
ES (2) ES495329A0 (ja)
FI (1) FI72967C (ja)
FR (1) FR2465710A1 (ja)
GB (1) GB2059963B (ja)
GR (1) GR70049B (ja)
HK (1) HK59383A (ja)
HU (1) HU183215B (ja)
IE (1) IE50268B1 (ja)
IL (1) IL60999A (ja)
IN (3) IN151313B (ja)
IT (1) IT1133823B (ja)
KE (1) KE3307A (ja)
LU (1) LU82797A1 (ja)
MX (1) MX7159E (ja)
NL (1) NL8005346A (ja)
NO (1) NO152128C (ja)
NZ (1) NZ195061A (ja)
PH (1) PH22628A (ja)
PL (1) PL128998B1 (ja)
PT (1) PT71839B (ja)
SE (1) SE448626B (ja)
SG (1) SG42983G (ja)
YU (3) YU41734B (ja)
ZA (1) ZA805476B (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
US6066671A (en) * 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
PT1423168E (pt) 2001-09-03 2006-05-31 Newron Pharm Spa Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
CZ2009367A3 (cs) * 2009-06-08 2010-06-16 Farmak, A.S. Postup prípravy 2-amino-3-benzoylfenylacetamidu (nepafenacu) s minimem vedlejších produktu
CN112794809B (zh) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 一种高纯度奈帕芬胺中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (ja) * 1967-07-31 1971-03-24
SE400966B (sv) * 1975-08-13 1978-04-17 Robins Co Inc A H Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
GR70049B (ja) 1982-07-26
KE3307A (en) 1983-08-19
DK154136B (da) 1988-10-17
ES8200329A1 (es) 1981-10-16
HU183215B (en) 1984-04-28
DK405780A (da) 1981-03-27
FR2465710B1 (ja) 1984-10-12
IL60999A (en) 1984-05-31
YU43306B (en) 1989-06-30
IE801946L (en) 1981-03-26
YU73183A (en) 1983-12-31
JPS5657751A (en) 1981-05-20
NZ195061A (en) 1984-04-27
JPH0141616B2 (ja) 1989-09-06
LU82797A1 (fr) 1982-05-10
BR8006042A (pt) 1981-04-07
ES8204715A1 (es) 1982-05-01
FI72967B (fi) 1987-04-30
IN151313B (ja) 1983-03-26
NL8005346A (nl) 1981-03-30
KR840000763B1 (ko) 1984-06-08
CH646138A5 (fr) 1984-11-15
NO152128B (no) 1985-04-29
FI72967C (fi) 1987-08-10
IL60999A0 (en) 1980-11-30
AU6211680A (en) 1981-04-02
YU41734B (en) 1987-12-31
ES503019A0 (es) 1982-05-01
HK59383A (en) 1983-12-02
AU532359B2 (en) 1983-09-29
NO152128C (no) 1985-08-07
PL128998B1 (en) 1984-03-31
GB2059963A (en) 1981-04-29
YU245080A (en) 1983-09-30
IT1133823B (it) 1986-07-24
FR2465710A1 (fr) 1981-03-27
YU73083A (en) 1983-12-31
IE50268B1 (en) 1986-03-19
DE3035688A1 (de) 1981-04-16
DK154136C (da) 1989-03-06
GB2059963B (en) 1983-04-20
SE8006668L (sv) 1981-03-27
YU43305B (en) 1989-06-30
MX7159E (es) 1987-12-02
ES495329A0 (es) 1981-10-16
FI803002A (fi) 1981-03-27
SG42983G (en) 1985-01-11
IN156254B (ja) 1985-06-08
IT8024948A0 (it) 1980-09-26
AT374170B (de) 1984-03-26
KR830004210A (ko) 1983-07-06
NO802834L (no) 1981-03-27
BE885393A (fr) 1981-01-16
PH22628A (en) 1988-10-28
PL226919A1 (ja) 1982-02-01
IN156255B (ja) 1985-06-08
PT71839B (en) 1981-06-25
PT71839A (en) 1980-10-01
DE3035688C2 (ja) 1990-05-17
CS227012B2 (en) 1984-04-16
ATA474580A (de) 1983-08-15
CA1128512A (en) 1982-07-27
SE448626B (sv) 1987-03-09
ZA805476B (en) 1981-11-25

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