AT371816B - Verfahren zur herstellung von neuen isocyanurs[urederivaten - Google Patents

Verfahren zur herstellung von neuen isocyanurs[urederivaten

Info

Publication number
AT371816B
AT371816B AT0655279A AT655279A AT371816B AT 371816 B AT371816 B AT 371816B AT 0655279 A AT0655279 A AT 0655279A AT 655279 A AT655279 A AT 655279A AT 371816 B AT371816 B AT 371816B
Authority
AT
Austria
Prior art keywords
urederivatives
isocyanurs
producing new
producing
new
Prior art date
Application number
AT0655279A
Other languages
English (en)
Other versions
ATA655279A (de
Original Assignee
Henkel Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel Kgaa filed Critical Henkel Kgaa
Priority to AT0655279A priority Critical patent/AT371816B/de
Priority to NL8005187A priority patent/NL8005187A/nl
Priority to DK395380A priority patent/DK395380A/da
Priority to SE8006716A priority patent/SE8006716L/xx
Priority to FI803108A priority patent/FI803108A/fi
Priority to DE19803037094 priority patent/DE3037094A1/de
Priority to SU802990883A priority patent/SU976849A3/ru
Priority to LU82824A priority patent/LU82824A1/de
Priority to GB8032108A priority patent/GB2060633B/en
Priority to CA000361580A priority patent/CA1159064A/en
Priority to DD80224376A priority patent/DD153370A5/de
Priority to ZA00806161A priority patent/ZA806161B/xx
Priority to IL61207A priority patent/IL61207A0/xx
Priority to FR8021417A priority patent/FR2484418B1/fr
Priority to IE2081/80A priority patent/IE51098B1/en
Priority to PL23179180A priority patent/PL231791A1/xx
Priority to HU802442A priority patent/HU182210B/hu
Priority to BE0/202350A priority patent/BE885555A/fr
Priority to PL1980227131A priority patent/PL125862B1/pl
Priority to IT25159/80A priority patent/IT1151093B/it
Priority to CH7487/80A priority patent/CH648554A5/de
Priority to NO802977A priority patent/NO802977L/no
Priority to US06/194,908 priority patent/US4393060A/en
Priority to ES495697A priority patent/ES495697A0/es
Priority to AU63063/80A priority patent/AU551079B2/en
Priority to MX809081U priority patent/MX7169E/es
Priority to JP14183580A priority patent/JPS5661374A/ja
Priority to NZ195195A priority patent/NZ195195A/en
Publication of ATA655279A publication Critical patent/ATA655279A/de
Application granted granted Critical
Publication of AT371816B publication Critical patent/AT371816B/de
Priority to CA000435840A priority patent/CA1179266A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/30—Only oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/30—Only oxygen atoms
    • C07D251/32—Cyanuric acid; Isocyanuric acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/30—Only oxygen atoms
    • C07D251/34—Cyanuric or isocyanuric esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AT0655279A 1979-10-08 1979-10-08 Verfahren zur herstellung von neuen isocyanurs[urederivaten AT371816B (de)

Priority Applications (29)

Application Number Priority Date Filing Date Title
AT0655279A AT371816B (de) 1979-10-08 1979-10-08 Verfahren zur herstellung von neuen isocyanurs[urederivaten
NL8005187A NL8005187A (nl) 1979-10-08 1980-09-17 Cytostatisch werkende farmaceutische preparaten, nieuwe isocyanuurzuurderivaten en werkwijzen ter bereiding ervan.
DK395380A DK395380A (da) 1979-10-08 1980-09-18 Isocyanursyreforbindelser med cytostatisk virkning og fremgangsmaade til fremstilling heraf
SE8006716A SE8006716L (sv) 1979-10-08 1980-09-25 Cytostatiskt verksamma beredningar, nya isocyanursyraderivat och forfarande for deras framstellning
FI803108A FI803108A (fi) 1979-10-08 1980-09-30 Nya cytostatiskt verkande isocyanursyrafoereningar och foerfarande foer deras framstaellning
DE19803037094 DE3037094A1 (de) 1979-10-08 1980-10-01 Cytostatisch wirkende pharmazeutische zubereitungen, neue isocyanursaeurederivate und verfahren zu ihrer herstellung
SU802990883A SU976849A3 (ru) 1979-10-08 1980-10-03 Способ получени производных изоциануровой кислоты
GB8032108A GB2060633B (en) 1979-10-08 1980-10-06 Isocyanuric acid derivatives preparation and pharmaceutical use thereof
CA000361580A CA1159064A (en) 1979-10-08 1980-10-06 Isocyanuric acid derivatives, method of preparation, therapeutic compositions with a cytostatic action and therapeutic method
DD80224376A DD153370A5 (de) 1979-10-08 1980-10-06 Verfahren zur herstellung neuer isocyanursaeureverbindungen
ZA00806161A ZA806161B (en) 1979-10-08 1980-10-06 Cytostatically active pharmaceutical preparation, new isocyanuric acid detivatives, and methods for their production
IL61207A IL61207A0 (en) 1979-10-08 1980-10-06 Cytostatically active pharmaceutical compositions comprising isocyanuric acid derivatives, certain such novel derivatives and their preparation
LU82824A LU82824A1 (de) 1979-10-08 1980-10-06 Cytostatisch wirkende pharmazeutische zubereitungen,neue isocyanursaeurederivate und verfahren zu ihrer herstellung
US06/194,908 US4393060A (en) 1979-10-08 1980-10-07 Isocyanuric acid derivatives, method of preparation, therapeutic compositions with a cytostatic action and therapeutic method
FR8021417A FR2484418B1 (fr) 1979-10-08 1980-10-07 Nouveaux derives d'acide isocyanurique, utiles notamment comme agents cytostatiques, et leur procede de preparation
HU802442A HU182210B (en) 1979-10-08 1980-10-07 Process for preparing new n up 1-substituted n up 3, n up 5-bis/2,3-epoxy-propyl/-isocyanuric acid compounds with cytostatic activity
BE0/202350A BE885555A (fr) 1979-10-08 1980-10-07 Preparations pharmaceutiques a activite cytostatique, nouveaux derives de l'acide isocyanurique et procedes pour leur preparation
PL1980227131A PL125862B1 (en) 1979-10-08 1980-10-07 Process for preparing novel n-substituted derivatives of diglycidylisocyanuric acid
IT25159/80A IT1151093B (it) 1979-10-08 1980-10-07 Preparato medicinale ad azione citostatica,nonche' derivati dell'acido iso anurico e procedimento per la loro preparazione
CH7487/80A CH648554A5 (de) 1979-10-08 1980-10-07 Glycidylisocyanursaeureverbindungen.
NO802977A NO802977L (no) 1979-10-08 1980-10-07 Nye isocyanursyreforbindelser med sytostatisk virkning og fremgangsmaater til deres fremstilling
IE2081/80A IE51098B1 (en) 1979-10-08 1980-10-07 Isocyanuric acid derivatives,preparation and pharmaceutical compositions thereof
ES495697A ES495697A0 (es) 1979-10-08 1980-10-07 Procedimiento para la obtencion de compuestos de acido di- glicidil-isocianurico n-sustituidos
PL23179180A PL231791A1 (de) 1979-10-08 1980-10-07
AU63063/80A AU551079B2 (en) 1979-10-08 1980-10-08 Glycidyliso cyanuric acid derivatives
MX809081U MX7169E (es) 1979-10-08 1980-10-08 Procedimiento para preparar compuestos n-substituidos del acido diglicidil-isocianurico
JP14183580A JPS5661374A (en) 1979-10-08 1980-10-08 Cytostatic drug* novel cyanuric acid derivative and manufacture thereof
NZ195195A NZ195195A (en) 1979-10-08 1980-10-08 1-hydrocarbyl-3,5-diglycidyl-hexahydro-s-triazine-2,4,6-triones
CA000435840A CA1179266A (en) 1979-10-08 1983-08-31 Isocyanuric acid derivatives, method of preparation, therapeutic compositions with a cytostatic action and therapeutic method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0655279A AT371816B (de) 1979-10-08 1979-10-08 Verfahren zur herstellung von neuen isocyanurs[urederivaten

Publications (2)

Publication Number Publication Date
ATA655279A ATA655279A (de) 1982-12-15
AT371816B true AT371816B (de) 1983-08-10

Family

ID=3587457

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0655279A AT371816B (de) 1979-10-08 1979-10-08 Verfahren zur herstellung von neuen isocyanurs[urederivaten

Country Status (27)

Country Link
US (1) US4393060A (de)
JP (1) JPS5661374A (de)
AT (1) AT371816B (de)
AU (1) AU551079B2 (de)
BE (1) BE885555A (de)
CA (1) CA1159064A (de)
CH (1) CH648554A5 (de)
DD (1) DD153370A5 (de)
DE (1) DE3037094A1 (de)
DK (1) DK395380A (de)
ES (1) ES495697A0 (de)
FI (1) FI803108A (de)
FR (1) FR2484418B1 (de)
GB (1) GB2060633B (de)
HU (1) HU182210B (de)
IE (1) IE51098B1 (de)
IL (1) IL61207A0 (de)
IT (1) IT1151093B (de)
LU (1) LU82824A1 (de)
MX (1) MX7169E (de)
NL (1) NL8005187A (de)
NO (1) NO802977L (de)
NZ (1) NZ195195A (de)
PL (2) PL231791A1 (de)
SE (1) SE8006716L (de)
SU (1) SU976849A3 (de)
ZA (1) ZA806161B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT372382B (de) * 1980-08-14 1983-09-26 Henkel Kgaa Verfahren zur herstellung von neuen oxiranylisocyanursaeureverbindungen
DE3330640A1 (de) * 1983-08-25 1985-03-14 Henkel KGaA, 4000 Düsseldorf Verfahren zur addition von saeuren an glycidylverbindungen
JPS62187463A (ja) * 1986-02-13 1987-08-15 Nissan Chem Ind Ltd トリグリシジルイソシアヌレ−トの固化方法
FR2608153B1 (fr) * 1986-12-11 1989-06-02 Charbonnages Ste Chimique Di-bishydroxypropyle de l'acide cyanurique, ses derives trisubstitues et leur procede de fabrication
FR2608154B1 (fr) * 1986-12-11 1989-06-02 Charbonnages Ste Chimique Dichlorhydrine de l'acide cyanurique, ses derives trisubstitues et leur procede de preparation
JP2952707B2 (ja) * 1990-10-29 1999-09-27 共同薬品株式会社 イソシアヌル酸誘導体、その製造法および用途
US5324720A (en) * 1992-03-20 1994-06-28 Merck & Co., Inc. Methods of achieving antitumor activity using 16-membered-macrolide-type compounds
KR20020025091A (ko) * 1999-06-30 2002-04-03 무네유키 가코우 벤즈 이미다졸 화합물 및 그것을 함유하는 의약
JP2012025688A (ja) * 2010-07-22 2012-02-09 National Institute Of Advanced Industrial Science & Technology エポキシ化合物の製造方法
JP6555930B2 (ja) * 2015-05-21 2019-08-07 株式会社カネカ イソシアヌレート化合物の製造方法
JP6513012B2 (ja) * 2015-09-11 2019-05-15 四国化成工業株式会社 ジグリシジルイソシアヌレート化合物、樹脂組成物およびその利用
US10450475B2 (en) * 2015-11-17 2019-10-22 Ennis Paint, Inc. Traffic marking compositions containing polyfunctional amines
CN108203502B (zh) * 2018-01-13 2020-04-21 宏峰行化工(深圳)有限公司 一种水溶性交联剂及其在水性树脂中的应用
WO2022172823A1 (ja) * 2021-02-15 2022-08-18 株式会社Adeka 電解めっき液用添加剤、電解めっき液、電解めっき方法及び金属層の製造方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD51773A (de) *
US3132142A (en) * 1961-04-24 1964-05-05 Spencer Chem Co Isocyanurate compounds
US3910908A (en) * 1965-05-17 1975-10-07 Celanese Coatings Co Triglycidyl isocyanurate preparation
CH532158A (de) * 1969-12-10 1972-12-31 Ciba Geigy Ag Verwendung N-heterocyclischer Perfluoralkylmonocarbonsäureester zum Veredeln von textilem Fasermaterial
US3920689A (en) * 1969-12-10 1975-11-18 Ciba Geigy Ag N-heterocyclic perfluoroalkylmonocarboxylic acid esters, processes for their manufacture and their use
US3793321A (en) * 1970-07-02 1974-02-19 Ciba Geigy Ag Process for the manufacture of triglycidylisocyanurate
US3779949A (en) * 1971-11-01 1973-12-18 Ciba Geigy Ag New adducts, containing epoxide groups, from polyepoxide compounds and binuclear n-heterocyclic compounds
CH581628A5 (de) * 1973-02-02 1976-11-15 Ciba Geigy Ag
JPS5328917B2 (de) * 1974-07-22 1978-08-17
JPS5114515A (ja) * 1974-07-25 1976-02-05 Kubota Ltd Nainenkikan
JPS53144955A (en) * 1977-05-23 1978-12-16 Mitsubishi Rayon Co Ltd Reinforced polyethylene terephthalate composition and its production
NL174157C (nl) * 1977-07-05 Teijin Ltd Hardbare polyester en gevormde al dan niet geharde producten vervaardigd onder toepassing van deze hardbare polyester.
US4292151A (en) * 1978-03-01 1981-09-29 Teijin Limited Process for preparing a cured copolyetherester elastomeric composition
DE2907349C2 (de) * 1979-02-24 1982-09-16 Henkel KGaA, 4000 Düsseldorf Arzneimittel mit cytostatischer Wirksamkeit
AT372382B (de) * 1980-08-14 1983-09-26 Henkel Kgaa Verfahren zur herstellung von neuen oxiranylisocyanursaeureverbindungen

Also Published As

Publication number Publication date
IT8025159A0 (it) 1980-10-07
CH648554A5 (de) 1985-03-29
PL231791A1 (de) 1982-02-01
FI803108A (fi) 1981-04-09
AU6306380A (en) 1981-04-16
NZ195195A (en) 1984-02-03
SU976849A3 (ru) 1982-11-23
PL227131A1 (de) 1981-10-30
AU551079B2 (en) 1986-04-17
PL125862B1 (en) 1983-06-30
CA1159064A (en) 1983-12-20
IE802081L (en) 1981-04-08
DD153370A5 (de) 1982-01-06
HU182210B (en) 1983-12-28
ES8201576A1 (es) 1981-12-16
DK395380A (da) 1981-04-09
FR2484418A1 (fr) 1981-12-18
IE51098B1 (en) 1986-10-01
BE885555A (fr) 1981-04-07
LU82824A1 (de) 1981-06-04
NO802977L (no) 1981-04-09
ES495697A0 (es) 1981-12-16
GB2060633A (en) 1981-05-07
SE8006716L (sv) 1981-04-09
FR2484418B1 (fr) 1985-09-06
ZA806161B (en) 1981-09-30
JPS5661374A (en) 1981-05-26
DE3037094A1 (de) 1981-04-16
IT1151093B (it) 1986-12-17
ATA655279A (de) 1982-12-15
NL8005187A (nl) 1981-04-10
GB2060633B (en) 1984-03-21
MX7169E (es) 1987-12-14
IL61207A0 (en) 1980-12-31
US4393060A (en) 1983-07-12

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