LT2271658T - Antioksidantai uždegimo moduliatoriai:oleanolio rūgšties c-17 patvirtinti dariniai - Google Patents

Antioksidantai uždegimo moduliatoriai:oleanolio rūgšties c-17 patvirtinti dariniai

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Publication number
LT2271658T
LT2271658T LTEP09732769.6T LT09732769T LT2271658T LT 2271658 T LT2271658 T LT 2271658T LT 09732769 T LT09732769 T LT 09732769T LT 2271658 T LT2271658 T LT 2271658T
Authority
LT
Lithuania
Prior art keywords
acid derivatives
oleanolic acid
antioxidant inflammation
inflammation modulators
homologated oleanolic
Prior art date
Application number
LTEP09732769.6T
Other languages
English (en)
Lithuanian (lt)
Inventor
Xin Jiang
Melean Visnick
Jack Greiner
Xiaofeng Liu
Stephen S. Szucs
Original Assignee
Reata Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reata Pharmaceuticals, Inc. filed Critical Reata Pharmaceuticals, Inc.
Publication of LT2271658T publication Critical patent/LT2271658T/lt

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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/47—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of rings being part of condensed ring systems
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    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
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  • Animal Behavior & Ethology (AREA)
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LTEP09732769.6T 2008-04-18 2009-04-20 Antioksidantai uždegimo moduliatoriai:oleanolio rūgšties c-17 patvirtinti dariniai LT2271658T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4636608P 2008-04-18 2008-04-18
US11129408P 2008-11-04 2008-11-04
PCT/US2009/041176 WO2009129548A1 (en) 2008-04-18 2009-04-20 Antioxidant inflammation modulators: c-17 homologated oleanolic acid derivatives

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LT2271658T true LT2271658T (lt) 2017-02-27

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US6326507B1 (en) 1998-06-19 2001-12-04 Trustees Of Dartmouth College Therapeutic compounds and methods of use
NZ556673A (en) 2005-02-03 2010-03-26 Gen Hospital Corp Method for treating gefitinib and/or erlotinib resistant cancer with an EGFR inhibitor
EP3488866A1 (en) 2005-11-04 2019-05-29 Wyeth LLC Antineoplastic combinations with mtor inhibitor, herceptin, and/or hki-272
US8022216B2 (en) 2007-10-17 2011-09-20 Wyeth Llc Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
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EA020156B1 (ru) 2014-09-30
BRPI0911422B1 (pt) 2021-02-02
EP2271658A1 (en) 2011-01-12
BRPI0911422A2 (pt) 2017-12-05
PT2271658T (pt) 2017-02-13
CN104250280A (zh) 2014-12-31
JP2011518192A (ja) 2011-06-23
US8394967B2 (en) 2013-03-12
MX2010011439A (es) 2011-01-25
ES2613964T3 (es) 2017-05-29
CA2721666A1 (en) 2009-10-22
AU2009237581B2 (en) 2014-07-10
IL208759A0 (en) 2010-12-30
US20110245206A1 (en) 2011-10-06

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