SI2271658T1 - Antioksidantni modulatorji vnetja: C-17 homologirani derivati oleanolne kisline - Google Patents

Antioksidantni modulatorji vnetja: C-17 homologirani derivati oleanolne kisline

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Publication number
SI2271658T1
SI2271658T1 SI200931602A SI200931602A SI2271658T1 SI 2271658 T1 SI2271658 T1 SI 2271658T1 SI 200931602 A SI200931602 A SI 200931602A SI 200931602 A SI200931602 A SI 200931602A SI 2271658 T1 SI2271658 T1 SI 2271658T1
Authority
SI
Slovenia
Prior art keywords
acid derivatives
oleanolic acid
antioxidant inflammation
inflammation modulators
homologated oleanolic
Prior art date
Application number
SI200931602A
Other languages
English (en)
Inventor
Xin Jiang
Melean Visnick
Jack Greiner
Xiaofeng Liu
Stephen S. Szucs
Original Assignee
Reata Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reata Pharmaceuticals, Inc. filed Critical Reata Pharmaceuticals, Inc.
Publication of SI2271658T1 publication Critical patent/SI2271658T1/sl

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    • C07C255/45Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C255/47Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of rings being part of condensed ring systems
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SI200931602A 2008-04-18 2009-04-20 Antioksidantni modulatorji vnetja: C-17 homologirani derivati oleanolne kisline SI2271658T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US4636608P 2008-04-18 2008-04-18
US11129408P 2008-11-04 2008-11-04
PCT/US2009/041176 WO2009129548A1 (en) 2008-04-18 2009-04-20 Antioxidant inflammation modulators: c-17 homologated oleanolic acid derivatives
EP09732769.6A EP2271658B1 (en) 2008-04-18 2009-04-20 Antioxidant inflammation modulators: c-17 homologated oleanolic acid derivatives

Publications (1)

Publication Number Publication Date
SI2271658T1 true SI2271658T1 (sl) 2017-03-31

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SI200931602A SI2271658T1 (sl) 2008-04-18 2009-04-20 Antioksidantni modulatorji vnetja: C-17 homologirani derivati oleanolne kisline

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US (3) US7943778B2 (sl)
EP (1) EP2271658B1 (sl)
JP (2) JP5588966B2 (sl)
KR (2) KR101782020B1 (sl)
CN (2) CN102066398B (sl)
AU (2) AU2009237581C1 (sl)
BR (1) BRPI0911422B8 (sl)
CA (1) CA2721666C (sl)
CO (1) CO6311107A2 (sl)
CY (1) CY1118475T1 (sl)
DK (1) DK2271658T3 (sl)
EA (1) EA020156B1 (sl)
ES (1) ES2613964T3 (sl)
HK (2) HK1152713A1 (sl)
HR (1) HRP20170102T1 (sl)
HU (1) HUE033288T2 (sl)
IL (1) IL208759B (sl)
LT (1) LT2271658T (sl)
ME (1) ME02751B (sl)
MX (1) MX2010011439A (sl)
NZ (1) NZ588711A (sl)
PL (1) PL2271658T3 (sl)
PT (1) PT2271658T (sl)
RS (1) RS55631B1 (sl)
SI (1) SI2271658T1 (sl)
TW (1) TWI584808B (sl)
WO (1) WO2009129548A1 (sl)
ZA (1) ZA201007589B (sl)

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CN103110948A (zh) 2005-11-04 2013-05-22 惠氏公司 mTOR抑制剂、赫赛汀和/或HKI-272的抗肿瘤组合
US8022216B2 (en) 2007-10-17 2011-09-20 Wyeth Llc Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
CN108434151A (zh) 2008-01-11 2018-08-24 里亚塔医药公司 合成三萜类化合物及用以治病之方法
WO2009146218A2 (en) 2008-04-18 2009-12-03 Reata Pharmaceuticals, Inc. Compounds including an anti-inflammatory pharmacore and methods of use
MX2010011439A (es) 2008-04-18 2011-01-25 Reata Pharmaceuticals Inc Moduladores de inflamacion antioxidantes: derivados del acido oleanolico homologacion c-17.
EA022588B1 (ru) 2008-04-18 2016-01-29 Ритэ Фамэсутикл, Инк. Антиоксидантные модуляторы воспаления: производные олеанолевой кислоты с насыщением в с-кольце
TW201004627A (en) 2008-04-18 2010-02-01 Reata Pharmaceuticals Inc Antioxidant inflammation modulators: novel derivatives of oleanolic acid
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