BRPI0911457A2 - moduladores inflamatórios antioxidantes; ácido oleanólico derivados com amina e outras modificações em c-17 - Google Patents
moduladores inflamatórios antioxidantes; ácido oleanólico derivados com amina e outras modificações em c-17Info
- Publication number
- BRPI0911457A2 BRPI0911457A2 BRPI0911457A BRPI0911457A BRPI0911457A2 BR PI0911457 A2 BRPI0911457 A2 BR PI0911457A2 BR PI0911457 A BRPI0911457 A BR PI0911457A BR PI0911457 A BRPI0911457 A BR PI0911457A BR PI0911457 A2 BRPI0911457 A2 BR PI0911457A2
- Authority
- BR
- Brazil
- Prior art keywords
- amine
- derived
- modifications
- oleanolic acid
- inflammatory modulators
- Prior art date
Links
- MIJYXULNPSFWEK-GTOFXWBISA-N 3beta-hydroxyolean-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MIJYXULNPSFWEK-GTOFXWBISA-N 0.000 title 1
- JKLISIRFYWXLQG-UHFFFAOYSA-N Epioleonolsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4CCC3C21C JKLISIRFYWXLQG-UHFFFAOYSA-N 0.000 title 1
- YBRJHZPWOMJYKQ-UHFFFAOYSA-N Oleanolic acid Natural products CC1(C)CC2C3=CCC4C5(C)CCC(O)C(C)(C)C5CCC4(C)C3(C)CCC2(C1)C(=O)O YBRJHZPWOMJYKQ-UHFFFAOYSA-N 0.000 title 1
- MIJYXULNPSFWEK-UHFFFAOYSA-N Oleanolinsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4=CCC3C21C MIJYXULNPSFWEK-UHFFFAOYSA-N 0.000 title 1
- 150000001412 amines Chemical class 0.000 title 1
- 239000003963 antioxidant agent Substances 0.000 title 1
- 230000003078 antioxidant effect Effects 0.000 title 1
- 230000002757 inflammatory effect Effects 0.000 title 1
- 238000012986 modification Methods 0.000 title 1
- 230000004048 modification Effects 0.000 title 1
- 229940100243 oleanolic acid Drugs 0.000 title 1
- HZLWUYJLOIAQFC-UHFFFAOYSA-N prosapogenin PS-A Natural products C12CC(C)(C)CCC2(C(O)=O)CCC(C2(CCC3C4(C)C)C)(C)C1=CCC2C3(C)CCC4OC1OCC(O)C(O)C1O HZLWUYJLOIAQFC-UHFFFAOYSA-N 0.000 title 1
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- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4634208P | 2008-04-18 | 2008-04-18 | |
US61/046,342 | 2008-04-18 | ||
US11116908P | 2008-11-04 | 2008-11-04 | |
US61/111,169 | 2008-11-04 | ||
PCT/US2009/041172 WO2009129546A1 (en) | 2008-04-18 | 2009-04-20 | Antioxidant inflammation modulators: oleanolic acid derivatives with amino and other modifications at c-17 |
Publications (2)
Publication Number | Publication Date |
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BRPI0911457A2 true BRPI0911457A2 (pt) | 2015-10-06 |
BRPI0911457B1 BRPI0911457B1 (pt) | 2021-09-21 |
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Application Number | Title | Priority Date | Filing Date |
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BRPI0911457-2A BRPI0911457B1 (pt) | 2008-04-18 | 2009-04-20 | Compostos moduladores inflamatórios antioxidantes, composição farmacêutica, bem como seu uso |
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BR (1) | BRPI0911457B1 (pt) |
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BRPI0911457B1 (pt) | 2021-09-21 |
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