KR20230118887A - 유전자 조작 세포 및 이의 용도 - Google Patents
유전자 조작 세포 및 이의 용도 Download PDFInfo
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- KR20230118887A KR20230118887A KR1020237022356A KR20237022356A KR20230118887A KR 20230118887 A KR20230118887 A KR 20230118887A KR 1020237022356 A KR1020237022356 A KR 1020237022356A KR 20237022356 A KR20237022356 A KR 20237022356A KR 20230118887 A KR20230118887 A KR 20230118887A
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A61K39/001111—Immunoglobulin superfamily
- A61K39/001112—CD19 or B4
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- A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
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- A61K40/35—Cytokines
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C07K2319/50—Fusion polypeptide containing protease site
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- Engineering & Computer Science (AREA)
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- Immunology (AREA)
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- Molecular Biology (AREA)
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- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
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- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063120980P | 2020-12-03 | 2020-12-03 | |
| US202063120948P | 2020-12-03 | 2020-12-03 | |
| US202063120799P | 2020-12-03 | 2020-12-03 | |
| US63/120,980 | 2020-12-03 | ||
| US63/120,799 | 2020-12-03 | ||
| US63/120,948 | 2020-12-03 | ||
| PCT/US2021/072646 WO2022120334A1 (en) | 2020-12-03 | 2021-12-01 | Genetically engineered cells and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20230118887A true KR20230118887A (ko) | 2023-08-14 |
Family
ID=79927264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020237022356A Pending KR20230118887A (ko) | 2020-12-03 | 2021-12-01 | 유전자 조작 세포 및 이의 용도 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US12269888B2 (https=) |
| EP (1) | EP4255922A1 (https=) |
| JP (1) | JP2023553419A (https=) |
| KR (1) | KR20230118887A (https=) |
| AU (1) | AU2021392032A1 (https=) |
| CA (1) | CA3201621A1 (https=) |
| IL (1) | IL303269A (https=) |
| MX (1) | MX2023006395A (https=) |
| TW (1) | TW202237827A (https=) |
| WO (1) | WO2022120334A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3210702A1 (en) * | 2021-04-07 | 2022-10-13 | Century Therapeutics, Inc. | Gene transfer vectors and methods of engineering cells |
| IL314801A (en) | 2022-02-22 | 2024-10-01 | Juno Therapeutics Inc | Proteinase 3 (PR3) Chimeric Autoantigen Receptor T Cells and Related Methods and Uses |
| JP2025522360A (ja) | 2022-06-08 | 2025-07-15 | センチュリー セラピューティクス,インコーポレイテッド | Cd16変異体およびnkg2dを発現する遺伝子操作した細胞ならびにその使用 |
| CA3257650A1 (en) * | 2022-06-08 | 2023-12-14 | Century Therapeutics, Inc. | Immunoeffector cells derived from genetically modified, multipotential stem cells with membrane IL-12 and their uses |
| KR20250143301A (ko) | 2022-11-10 | 2025-10-01 | 센츄리 쎄라퓨틱스 인코포레이티드 | 항-넥틴4 키메라 항원 수용체를 갖는 유전자 조작 세포 및 이의 용도 |
| TW202523837A (zh) * | 2023-10-30 | 2025-06-16 | 日商武田藥品工業股份有限公司 | 用於製造細胞毒性t細胞之方法 |
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