SG11202012015YA - Compositions and methods for the modulation of adaptive immunity - Google Patents
Compositions and methods for the modulation of adaptive immunityInfo
- Publication number
- SG11202012015YA SG11202012015YA SG11202012015YA SG11202012015YA SG11202012015YA SG 11202012015Y A SG11202012015Y A SG 11202012015YA SG 11202012015Y A SG11202012015Y A SG 11202012015YA SG 11202012015Y A SG11202012015Y A SG 11202012015YA SG 11202012015Y A SG11202012015Y A SG 11202012015YA
- Authority
- SG
- Singapore
- Prior art keywords
- modulation
- compositions
- methods
- adaptive immunity
- immunity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862682276P | 2018-06-08 | 2018-06-08 | |
PCT/US2019/036050 WO2019236998A1 (en) | 2018-06-08 | 2019-06-07 | Compositions and methods for the modulation of adaptive immunity |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202012015YA true SG11202012015YA (en) | 2021-01-28 |
Family
ID=68769461
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202012015YA SG11202012015YA (en) | 2018-06-08 | 2019-06-07 | Compositions and methods for the modulation of adaptive immunity |
Country Status (9)
Country | Link |
---|---|
US (1) | US20190382759A1 (en) |
EP (1) | EP3801641A4 (en) |
JP (1) | JP2021526860A (en) |
KR (1) | KR20210060429A (en) |
CN (1) | CN113286619A (en) |
AU (1) | AU2019281006A1 (en) |
CA (1) | CA3102783A1 (en) |
SG (1) | SG11202012015YA (en) |
WO (1) | WO2019236998A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3765094A4 (en) | 2018-03-15 | 2021-12-22 | KSQ Therapeutics, Inc. | Gene-regulating compositions and methods for improved immunotherapy |
WO2019236982A1 (en) | 2018-06-08 | 2019-12-12 | Locana, Inc. | Rna-targeting fusion protein compositions and methods for use |
MX2021008487A (en) * | 2019-01-14 | 2021-11-12 | Univ Rochester | Targeted nuclear rna cleavage and polyadenylation with crispr-cas. |
US11661459B2 (en) | 2020-12-03 | 2023-05-30 | Century Therapeutics, Inc. | Artificial cell death polypeptide for chimeric antigen receptor and uses thereof |
WO2023150131A1 (en) * | 2022-02-01 | 2023-08-10 | The Regents Of The University Of California | Method of regulating alternative polyadenylation in rna |
CN114848808B (en) * | 2022-03-24 | 2023-04-25 | 四川大学 | Immunopotentiator based on cationic lipopolypeptide and cytokine, and preparation method and application thereof |
CN116949011A (en) * | 2022-04-26 | 2023-10-27 | 中国科学院动物研究所 | Isolated Cas13 protein, gene editing system based on same and use thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2019500899A (en) * | 2015-11-23 | 2019-01-17 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Cellular RNA tracking and manipulation through nuclear delivery of CRISPR / Cas9 |
US20180362975A1 (en) * | 2015-12-04 | 2018-12-20 | Novartis Ag | Compositions and methods for immunooncology |
US20210285010A1 (en) * | 2016-10-31 | 2021-09-16 | University Of Florida Research Foundation, Inc. | Compositions and methods for impeding transcription of expanded microsatellite repeats |
KR102185464B1 (en) * | 2017-03-15 | 2020-12-03 | 매사추세츠 인스티튜트 오브 테크놀로지 | New CAS13B Ortholog CRISPR Enzyme and System |
US10392616B2 (en) * | 2017-06-30 | 2019-08-27 | Arbor Biotechnologies, Inc. | CRISPR RNA targeting enzymes and systems and uses thereof |
-
2019
- 2019-06-07 EP EP19814000.6A patent/EP3801641A4/en active Pending
- 2019-06-07 JP JP2021518054A patent/JP2021526860A/en active Pending
- 2019-06-07 US US16/434,787 patent/US20190382759A1/en not_active Abandoned
- 2019-06-07 AU AU2019281006A patent/AU2019281006A1/en active Pending
- 2019-06-07 CA CA3102783A patent/CA3102783A1/en active Pending
- 2019-06-07 WO PCT/US2019/036050 patent/WO2019236998A1/en unknown
- 2019-06-07 SG SG11202012015YA patent/SG11202012015YA/en unknown
- 2019-06-07 KR KR1020217000507A patent/KR20210060429A/en unknown
- 2019-06-07 CN CN201980051039.7A patent/CN113286619A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
KR20210060429A (en) | 2021-05-26 |
CA3102783A1 (en) | 2019-12-12 |
EP3801641A1 (en) | 2021-04-14 |
EP3801641A4 (en) | 2022-09-28 |
CN113286619A (en) | 2021-08-20 |
JP2021526860A (en) | 2021-10-11 |
WO2019236998A1 (en) | 2019-12-12 |
AU2019281006A1 (en) | 2021-01-28 |
US20190382759A1 (en) | 2019-12-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL277079A (en) | Cartyrin compositions and methods for use | |
SG11202012015YA (en) | Compositions and methods for the modulation of adaptive immunity | |
IL280134A (en) | Anti-cd112r compositions and methods | |
EP3589646A4 (en) | Cd19 compositions and methods for immunotherapy | |
IL268970A (en) | Novel compositions and methods | |
GB202201859D0 (en) | Novel methods and compositions | |
WO2015120138A3 (en) | AGENTS THAT MODULATE RGMb-NEOGENIN-BMP SIGNALING AND METHODS OF USE THEREOF | |
IL266562A (en) | Methods and compositions for adaptive immune modulation | |
IL281015A (en) | Methods and compositions for the modification of plants | |
ZA202101362B (en) | Compositions and methods for treating the eye | |
SG11202103033WA (en) | Compositions and methods for the treatment of presbyopia | |
SG11202104448WA (en) | Compositions and methods | |
ZA202101342B (en) | Compositions and methods for treating the eye | |
EP3844500A4 (en) | Rp182 compositions and methods | |
GB201815402D0 (en) | Compositions and methods and uses relating thereto | |
GB2578519B (en) | Compositions and methods and uses relating thereto | |
IL283850A (en) | Cannabis compositions and methods | |
GB201817444D0 (en) | Methods and compositions | |
IL264977A (en) | Methods and compositions for the treatment of melanoma | |
ZA202101360B (en) | Compositions and methods for treating the eye | |
ZA202101361B (en) | Compositions and methods for treating the eye | |
GB201819987D0 (en) | Methods and compositions | |
IL273699A (en) | Sulfasalazine salt compositions and methods of using the same | |
EP3628009A4 (en) | Compositions and methods for improving cognition | |
IL281835A (en) | Anti-malaria compositions and methods |