KR101527232B1 - Akt 단백질 키나제 억제제로서의 시클로펜타〔d〕피리미딘 - Google Patents
Akt 단백질 키나제 억제제로서의 시클로펜타〔d〕피리미딘 Download PDFInfo
- Publication number
- KR101527232B1 KR101527232B1 KR1020097002436A KR20097002436A KR101527232B1 KR 101527232 B1 KR101527232 B1 KR 101527232B1 KR 1020097002436 A KR1020097002436 A KR 1020097002436A KR 20097002436 A KR20097002436 A KR 20097002436A KR 101527232 B1 KR101527232 B1 KR 101527232B1
- Authority
- KR
- South Korea
- Prior art keywords
- piperazin
- methyl
- cyclopenta
- dihydro
- propan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 0 *C1c2c(N3C(*)CNCC3)ncnc2C(*)(*)C1 Chemical compound *C1c2c(N3C(*)CNCC3)ncnc2C(*)(*)C1 0.000 description 1
- FVNZUMZSHCJXOG-UHFFFAOYSA-N CC(C(Cc(cc1)ccc1Cl)C1(CC1)N)=O Chemical compound CC(C(Cc(cc1)ccc1Cl)C1(CC1)N)=O FVNZUMZSHCJXOG-UHFFFAOYSA-N 0.000 description 1
- CQSISKSBGLSTRW-UHFFFAOYSA-N CC(C(Cc(cc1F)ccc1Cl)CN)=O Chemical compound CC(C(Cc(cc1F)ccc1Cl)CN)=O CQSISKSBGLSTRW-UHFFFAOYSA-N 0.000 description 1
- TXCSKCRMRMORFI-BPNWFJGMSA-N CC(C)NCC(C(N(CC1)CCN1c1ncnc2c1[C@H](C)CC2)=O)(c(cc1)ccc1Cl)O Chemical compound CC(C)NCC(C(N(CC1)CCN1c1ncnc2c1[C@H](C)CC2)=O)(c(cc1)ccc1Cl)O TXCSKCRMRMORFI-BPNWFJGMSA-N 0.000 description 1
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81876206P | 2006-07-06 | 2006-07-06 | |
| US60/818,762 | 2006-07-06 | ||
| PCT/US2007/072876 WO2008006032A1 (en) | 2006-07-06 | 2007-07-05 | Cyclopenta [d] pyrimidines as akt protein kinase inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157007785A Division KR20150041164A (ko) | 2006-07-06 | 2007-07-05 | Akt 단백질 키나제 억제제로서의 시클로펜타〔d〕피리미딘 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20090029287A KR20090029287A (ko) | 2009-03-20 |
| KR101527232B1 true KR101527232B1 (ko) | 2015-06-09 |
Family
ID=38686844
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157007785A Withdrawn KR20150041164A (ko) | 2006-07-06 | 2007-07-05 | Akt 단백질 키나제 억제제로서의 시클로펜타〔d〕피리미딘 |
| KR1020097002436A Expired - Fee Related KR101527232B1 (ko) | 2006-07-06 | 2007-07-05 | Akt 단백질 키나제 억제제로서의 시클로펜타〔d〕피리미딘 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157007785A Withdrawn KR20150041164A (ko) | 2006-07-06 | 2007-07-05 | Akt 단백질 키나제 억제제로서의 시클로펜타〔d〕피리미딘 |
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| UA (1) | UA99597C2 (enExample) |
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