KR101278732B1 - Ｉａｐ의 피롤리딘 억제제 - Google Patents

Ｉａｐ의 피롤리딘 억제제 Download PDF

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Publication number
KR101278732B1
KR101278732B1 KR1020077013861A KR20077013861A KR101278732B1 KR 101278732 B1 KR101278732 B1 KR 101278732B1 KR 1020077013861 A KR1020077013861 A KR 1020077013861A KR 20077013861 A KR20077013861 A KR 20077013861A KR 101278732 B1 KR101278732 B1 KR 101278732B1
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South Korea
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mmol
alkyl
mixture
methyl
minutes
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Expired - Lifetime
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Korean (ko)
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KR20070089174A (ko
Inventor
프레데릭 코헨
비키 시아오-웨이 쯔이
쿠옹 리
존 에이. 플리게어
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제넨테크, 인크.
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Application filed by 제넨테크, 인크. filed Critical 제넨테크, 인크.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
KR1020077013861A 2004-12-20 2005-12-19 Ｉａｐ의 피롤리딘 억제제 Expired - Lifetime KR101278732B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63820204P 2004-12-20 2004-12-20
US60/638,202 2004-12-20
PCT/US2005/046161 WO2006069063A1 (en) 2004-12-20 2005-12-19 Pyrrolidine inhibitors of iap

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020127028837A Division KR20120127754A (ko) 2004-12-20 2005-12-19 Ｉａｐ의 피롤리딘 억제제

Publications (2)

Publication Number Publication Date
KR20070089174A KR20070089174A (ko) 2007-08-30
KR101278732B1 true KR101278732B1 (ko) 2013-07-09

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ID=36129810

Family Applications (2)

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KR1020077013861A Expired - Lifetime KR101278732B1 (ko) 2004-12-20 2005-12-19 Ｉａｐ의 피롤리딘 억제제
KR1020127028837A Ceased KR20120127754A (ko) 2004-12-20 2005-12-19 Ｉａｐ의 피롤리딘 억제제

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020127028837A Ceased KR20120127754A (ko) 2004-12-20 2005-12-19 Ｉａｐ의 피롤리딘 억제제

Country Status (18)

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US (4) US20060167066A1 (https=)
EP (1) EP1836201B2 (https=)
JP (2) JP5007235B2 (https=)
KR (2) KR101278732B1 (https=)
CN (1) CN101146803A (https=)
AT (1) ATE477254T1 (https=)
AU (1) AU2005319305B2 (https=)
CA (1) CA2588921C (https=)
DE (1) DE602005022936D1 (https=)
DK (1) DK1836201T4 (https=)
EA (1) EA019420B1 (https=)
ES (1) ES2349110T5 (https=)
IL (1) IL183514A (https=)
MX (1) MX2007007195A (https=)
NO (1) NO339157B1 (https=)
NZ (1) NZ589670A (https=)
WO (1) WO2006069063A1 (https=)
ZA (1) ZA200704910B (https=)

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