AU2002253908A1 - A conserved xiap-interaction motif in caspase-9 and smac/diablo for mediating apoptosis - Google Patents

A conserved xiap-interaction motif in caspase-9 and smac/diablo for mediating apoptosis

Info

Publication number
AU2002253908A1
AU2002253908A1 AU2002253908A AU2002253908A AU2002253908A1 AU 2002253908 A1 AU2002253908 A1 AU 2002253908A1 AU 2002253908 A AU2002253908 A AU 2002253908A AU 2002253908 A AU2002253908 A AU 2002253908A AU 2002253908 A1 AU2002253908 A1 AU 2002253908A1
Authority
AU
Australia
Prior art keywords
diablo
xiap
smac
caspase
conserved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002253908A
Inventor
Emad S. Alnemri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thomas Jefferson University
Original Assignee
Thomas Jefferson University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas Jefferson University filed Critical Thomas Jefferson University
Publication of AU2002253908A1 publication Critical patent/AU2002253908A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • C12N9/6475—Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
AU2002253908A 2001-02-08 2002-02-06 A conserved xiap-interaction motif in caspase-9 and smac/diablo for mediating apoptosis Abandoned AU2002253908A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26796601P 2001-02-08 2001-02-08
US60/267,966 2001-02-08
PCT/US2002/003553 WO2003010184A2 (en) 2001-02-08 2002-02-06 A conserved xiap-interaction motif in caspase-9 and smac/diablo for mediating apoptosis

Publications (1)

Publication Number Publication Date
AU2002253908A1 true AU2002253908A1 (en) 2003-02-17

Family

ID=23020873

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002253908A Abandoned AU2002253908A1 (en) 2001-02-08 2002-02-06 A conserved xiap-interaction motif in caspase-9 and smac/diablo for mediating apoptosis

Country Status (2)

Country Link
AU (1) AU2002253908A1 (en)
WO (1) WO2003010184A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1723122B1 (en) 2004-03-01 2014-11-19 Board of Regents, The University of Texas System Dimeric small molecule potentiators of apoptosis
AU2005228950B2 (en) 2004-03-23 2012-02-02 Genentech, Inc. Azabicyclo-octane inhibitors of IAP
PT1778718E (en) 2004-07-02 2014-12-03 Genentech Inc Inhibitors of iap
DE602005022936D1 (en) 2004-12-20 2010-09-23 Genentech Inc PYRROLIDINES AS INHIBITORS OF IAP
JP5155184B2 (en) 2005-12-19 2013-02-27 ジェネンテック， インコーポレイテッド Inhibitors of IAP
NZ577150A (en) 2006-12-19 2012-04-27 Genentech Inc Imidazopyridine inhibitors of iap
CA2683392A1 (en) 2007-04-30 2008-11-06 Genentech, Inc. Inhibitors of iap
NZ590550A (en) 2008-08-02 2013-05-31 Genentech Inc Inhibitors of Apoptosis (IAP) for treating cancer

Also Published As

Publication number Publication date
WO2003010184A2 (en) 2003-02-06
WO2003010184A3 (en) 2003-08-14

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase