KR101146095B1 - 1-(β-D-글루코피라노실)-4-메틸-3-〔5-(4-플루오로페닐)-2-티에닐메틸〕벤젠 반수화물의 결정형 - Google Patents

1-(β-D-글루코피라노실)-4-메틸-3-〔5-(4-플루오로페닐)-2-티에닐메틸〕벤젠 반수화물의 결정형 Download PDF

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KR101146095B1
KR101146095B1 KR1020097013946A KR20097013946A KR101146095B1 KR 101146095 B1 KR101146095 B1 KR 101146095B1 KR 1020097013946 A KR1020097013946 A KR 1020097013946A KR 20097013946 A KR20097013946 A KR 20097013946A KR 101146095 B1 KR101146095 B1 KR 101146095B1
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fluorophenyl
thienylmethyl
methyl
glucopyranosyl
benzene
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KR20090086282A (ko
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스미히로 노무라
에이지 가와니시
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미쓰비시 타나베 파마 코퍼레이션
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    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04Carbocyclic radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
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    • A61P25/00Drugs for disorders of the nervous system
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    • A61P25/00Drugs for disorders of the nervous system
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    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
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    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
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    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
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  • Dermatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020097013946A 2006-12-04 2007-12-03 1-(β-D-글루코피라노실)-4-메틸-3-〔5-(4-플루오로페닐)-2-티에닐메틸〕벤젠 반수화물의 결정형 KR101146095B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US86842606P 2006-12-04 2006-12-04
JPJP-P-2006-327019 2006-12-04
US60/868,426 2006-12-04
JP2006327019 2006-12-04
PCT/JP2007/073729 WO2008069327A1 (en) 2006-12-04 2007-12-03 CRYSTALLINE FORM OF 1- (β-D-GLUCOPYRANOSYL) -4 -METHYL- 3- [5- (4 -FLUOROPHENYL) -2-THIENYLMETHYL] BENZENE HEMIHYDRATE

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KR20090086282A KR20090086282A (ko) 2009-08-11
KR101146095B1 true KR101146095B1 (ko) 2012-05-16

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US (2) US7943582B2 (ja)
EP (1) EP2102224B2 (ja)
JP (1) JP5159788B2 (ja)
KR (1) KR101146095B1 (ja)
CN (3) CN102675380A (ja)
AR (3) AR064099A1 (ja)
AU (1) AU2007329895C1 (ja)
BR (1) BRPI0718882B8 (ja)
CA (1) CA2671357C (ja)
CL (1) CL2007003487A1 (ja)
CO (1) CO6210719A2 (ja)
CR (1) CR10861A (ja)
DK (1) DK2102224T4 (ja)
EA (1) EA017103B1 (ja)
EC (1) ECSP099489A (ja)
ES (1) ES2456640T5 (ja)
GT (1) GT200900151A (ja)
IL (1) IL199032A (ja)
ME (1) ME01829B (ja)
MX (1) MX2009005857A (ja)
MY (1) MY153702A (ja)
NO (1) NO344354B1 (ja)
NZ (1) NZ577545A (ja)
PA (1) PA8759401A1 (ja)
PE (3) PE20110841A1 (ja)
PL (1) PL2102224T5 (ja)
PT (1) PT2102224E (ja)
RS (1) RS53274B2 (ja)
SI (1) SI2102224T2 (ja)
SV (1) SV2009003285A (ja)
TW (1) TWI403325B (ja)
UY (1) UY30730A1 (ja)
WO (1) WO2008069327A1 (ja)
ZA (1) ZA200903941B (ja)

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