KR101146095B1 - 1-(β-Ｄ-글루코피라노실)-4-메틸-3-〔5-(4-플루오로페닐)-2-티에닐메틸〕벤젠 반수화물의 결정형 - Google Patents

1-(β-Ｄ-글루코피라노실)-4-메틸-3-〔5-(4-플루오로페닐)-2-티에닐메틸〕벤젠 반수화물의 결정형 Download PDF

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KR101146095B1
KR101146095B1 KR1020097013946A KR20097013946A KR101146095B1 KR 101146095 B1 KR101146095 B1 KR 101146095B1 KR 1020097013946 A KR1020097013946 A KR 1020097013946A KR 20097013946 A KR20097013946 A KR 20097013946A KR 101146095 B1 KR101146095 B1 KR 101146095B1
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fluorophenyl
thienylmethyl
methyl
glucopyranosyl
benzene
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KR1020097013946A
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Korean (ko)
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KR20090086282A (ko
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스미히로 노무라
에이지 가와니시
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미쓰비시 타나베 파마 코퍼레이션
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    • C—CHEMISTRY; METALLURGY
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    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Diabetes (AREA)
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  • Obesity (AREA)
  • Hematology (AREA)
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  • Heart & Thoracic Surgery (AREA)
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  • Dermatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020097013946A 2006-12-04 2007-12-03 1-(β-Ｄ-글루코피라노실)-4-메틸-3-〔5-(4-플루오로페닐)-2-티에닐메틸〕벤젠 반수화물의 결정형 KR101146095B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US86842606P 2006-12-04 2006-12-04
JP2006327019 2006-12-04
JPJP-P-2006-327019 2006-12-04
US60/868,426 2006-12-04
PCT/JP2007/073729 WO2008069327A1 (en) 2006-12-04 2007-12-03 CRYSTALLINE FORM OF 1- (β-D-GLUCOPYRANOSYL) -4 -METHYL- 3- [5- (4 -FLUOROPHENYL) -2-THIENYLMETHYL] BENZENE HEMIHYDRATE

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KR20090086282A KR20090086282A (ko) 2009-08-11
KR101146095B1 true KR101146095B1 (ko) 2012-05-16

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KR1020097013946A KR101146095B1 (ko) 2006-12-04 2007-12-03 1-(β-Ｄ-글루코피라노실)-4-메틸-3-〔5-(4-플루오로페닐)-2-티에닐메틸〕벤젠 반수화물의 결정형

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US (2) US7943582B2 (ja)
EP (1) EP2102224B2 (ja)
JP (1) JP5159788B2 (ja)
KR (1) KR101146095B1 (ja)
CN (3) CN102675380A (ja)
AR (3) AR064099A1 (ja)
AU (1) AU2007329895C1 (ja)
BR (1) BRPI0718882B8 (ja)
CA (1) CA2671357C (ja)
CL (1) CL2007003487A1 (ja)
CO (1) CO6210719A2 (ja)
CR (1) CR10861A (ja)
DK (1) DK2102224T4 (ja)
EA (1) EA017103B1 (ja)
EC (1) ECSP099489A (ja)
ES (1) ES2456640T5 (ja)
GT (1) GT200900151A (ja)
IL (1) IL199032A (ja)
ME (1) ME01829B (ja)
MX (1) MX2009005857A (ja)
MY (1) MY153702A (ja)
NO (1) NO344354B1 (ja)
NZ (1) NZ577545A (ja)
PA (1) PA8759401A1 (ja)
PE (3) PE20130591A1 (ja)
PL (1) PL2102224T5 (ja)
PT (1) PT2102224E (ja)
RS (1) RS53274B2 (ja)
SI (1) SI2102224T2 (ja)
SV (1) SV2009003285A (ja)
TW (1) TWI403325B (ja)
UY (1) UY30730A1 (ja)
WO (1) WO2008069327A1 (ja)
ZA (1) ZA200903941B (ja)

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