BRPI0718882B8 - forma cristalina de hemi-hidrato de 1-(beta-dglicopiranosil)-4-metil-3-[5-(4-fluorfenil)-2- tienilmetil]benzeno, processo para preparação e composição compreendendo a mesma - Google Patents

forma cristalina de hemi-hidrato de 1-(beta-dglicopiranosil)-4-metil-3-[5-(4-fluorfenil)-2- tienilmetil]benzeno, processo para preparação e composição compreendendo a mesma

Info

Publication number
BRPI0718882B8
BRPI0718882B8 BRPI0718882A BRPI0718882A BRPI0718882B8 BR PI0718882 B8 BRPI0718882 B8 BR PI0718882B8 BR PI0718882 A BRPI0718882 A BR PI0718882A BR PI0718882 A BRPI0718882 A BR PI0718882A BR PI0718882 B8 BRPI0718882 B8 BR PI0718882B8
Authority
BR
Brazil
Prior art keywords
glycopyranosyl
thienylmethyl
fluorophenyl
methyl
beta
Prior art date
Application number
BRPI0718882A
Other languages
English (en)
Inventor
Kawanishi Eiji
Nomura Sumihiro
Original Assignee
Mitsubishi Tanabe Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38973167&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0718882(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mitsubishi Tanabe Pharma Corp filed Critical Mitsubishi Tanabe Pharma Corp
Publication of BRPI0718882A2 publication Critical patent/BRPI0718882A2/pt
Publication of BRPI0718882B1 publication Critical patent/BRPI0718882B1/pt
Publication of BRPI0718882B8 publication Critical patent/BRPI0718882B8/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

forma cristalina de hemi-hidrato de 1-(beta-d- glicopiranosil) -4-metil-3- [5- (4-fluorfenil) -2- tienilmetil] benzeno 5 uma nova forma cristal de hemi-hidrato de 1-(p-d- glicopiranosil)-4-metil-3-[5-(4-fluorfenil)-2-tienilmetil] benzeno, e que possui características favoráveis, é caracterizada por seu padrão de difração de energia de raios x e/ou por seu espectro infravermelho.
BRPI0718882A 2006-12-04 2007-12-03 forma cristalina de hemi-hidrato de 1-(beta-dglicopiranosil)-4-metil-3-[5-(4-fluorfenil)-2- tienilmetil]benzeno, processo para preparação e composição compreendendo a mesma BRPI0718882B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US86842606P 2006-12-04 2006-12-04
US60/868426 2006-12-04
JP2006-327019 2006-12-04
JP2006327019 2006-12-04
PCT/JP2007/073729 WO2008069327A1 (en) 2006-12-04 2007-12-03 CRYSTALLINE FORM OF 1- (β-D-GLUCOPYRANOSYL) -4 -METHYL- 3- [5- (4 -FLUOROPHENYL) -2-THIENYLMETHYL] BENZENE HEMIHYDRATE

Publications (3)

Publication Number Publication Date
BRPI0718882A2 BRPI0718882A2 (pt) 2014-09-16
BRPI0718882B1 BRPI0718882B1 (pt) 2021-03-23
BRPI0718882B8 true BRPI0718882B8 (pt) 2021-05-25

Family

ID=38973167

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0718882A BRPI0718882B8 (pt) 2006-12-04 2007-12-03 forma cristalina de hemi-hidrato de 1-(beta-dglicopiranosil)-4-metil-3-[5-(4-fluorfenil)-2- tienilmetil]benzeno, processo para preparação e composição compreendendo a mesma

Country Status (34)

Country Link
US (2) US7943582B2 (pt)
EP (1) EP2102224B2 (pt)
JP (1) JP5159788B2 (pt)
KR (1) KR101146095B1 (pt)
CN (3) CN102675380A (pt)
AR (3) AR064099A1 (pt)
AU (1) AU2007329895C1 (pt)
BR (1) BRPI0718882B8 (pt)
CA (1) CA2671357C (pt)
CL (1) CL2007003487A1 (pt)
CO (1) CO6210719A2 (pt)
CR (1) CR10861A (pt)
DK (1) DK2102224T4 (pt)
EA (1) EA017103B1 (pt)
EC (1) ECSP099489A (pt)
ES (1) ES2456640T5 (pt)
GT (1) GT200900151A (pt)
IL (1) IL199032A (pt)
ME (1) ME01829B (pt)
MX (1) MX2009005857A (pt)
MY (1) MY153702A (pt)
NO (1) NO344354B1 (pt)
NZ (1) NZ577545A (pt)
PA (1) PA8759401A1 (pt)
PE (3) PE20081201A1 (pt)
PL (1) PL2102224T5 (pt)
PT (1) PT2102224E (pt)
RS (1) RS53274B2 (pt)
SI (1) SI2102224T2 (pt)
SV (1) SV2009003285A (pt)
TW (1) TWI403325B (pt)
UY (1) UY30730A1 (pt)
WO (1) WO2008069327A1 (pt)
ZA (1) ZA200903941B (pt)

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