JPS60178855A - 新規なアミノグアニジン誘導体 - Google Patents

新規なアミノグアニジン誘導体

Info

Publication number
JPS60178855A
JPS60178855A JP59260996A JP26099684A JPS60178855A JP S60178855 A JPS60178855 A JP S60178855A JP 59260996 A JP59260996 A JP 59260996A JP 26099684 A JP26099684 A JP 26099684A JP S60178855 A JPS60178855 A JP S60178855A
Authority
JP
Japan
Prior art keywords
general formula
alkyl
acid addition
pharmaceutically acceptable
represent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59260996A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0226629B2 (en, 2012
Inventor
イストバン　エルツイ
イエノ　マロスフアルビ
ジヨルギイ　ラブロツキイ
アンドラス　バツロ
マリア　クハラ
イストバン　エレケス
ラスズロ　スザトマリイ
ラスズロ　ヤスズリツ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Works PLC
Original Assignee
Biogal Gyogyszergyar Rt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar Rt filed Critical Biogal Gyogyszergyar Rt
Publication of JPS60178855A publication Critical patent/JPS60178855A/ja
Publication of JPH0226629B2 publication Critical patent/JPH0226629B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/06—Compounds containing any of the groups, e.g. semicarbazides
    • C07C281/08—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones
    • C07C281/10—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones the carbon atom being further bound to an acyclic carbon atom or to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP59260996A 1983-12-12 1984-12-12 新規なアミノグアニジン誘導体 Granted JPS60178855A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU834222A HU190639B (en) 1983-12-12 1983-12-12 Process for production of new aminoguanidin derivatives
HU2251/4222/83 1983-12-12

Publications (2)

Publication Number Publication Date
JPS60178855A true JPS60178855A (ja) 1985-09-12
JPH0226629B2 JPH0226629B2 (en, 2012) 1990-06-12

Family

ID=10967376

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59260996A Granted JPS60178855A (ja) 1983-12-12 1984-12-12 新規なアミノグアニジン誘導体

Country Status (21)

Country Link
US (1) US4731383A (en, 2012)
JP (1) JPS60178855A (en, 2012)
KR (1) KR870001105B1 (en, 2012)
AT (1) AT394192B (en, 2012)
BE (1) BE901239A (en, 2012)
BG (3) BG44374A3 (en, 2012)
CA (1) CA1237129A (en, 2012)
CH (1) CH664955A5 (en, 2012)
DD (1) DD228246A5 (en, 2012)
DE (1) DE3445339A1 (en, 2012)
DK (1) DK164155C (en, 2012)
FI (1) FI79527C (en, 2012)
FR (1) FR2556343B1 (en, 2012)
GB (1) GB2151617B (en, 2012)
HU (1) HU190639B (en, 2012)
IL (1) IL73811A (en, 2012)
NL (1) NL193539C (en, 2012)
NO (1) NO159528C (en, 2012)
PL (2) PL140594B1 (en, 2012)
SE (1) SE462847B (en, 2012)
SU (2) SU1340583A3 (en, 2012)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612332A (en) * 1984-03-19 1997-03-18 Alteon Inc. Di- and triaminoguanidines, and methods of use
US5852009A (en) * 1984-03-19 1998-12-22 The Rockefeller University Compositions, including pharmaceutical compositions, for inhibiting the advanced glycosylation of proteins, and therapeutic methods based thereon
FR2669927B1 (fr) * 1990-11-29 1994-04-08 Adir Cie Nouveaux derives de guanidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
ES2103166B1 (es) * 1992-08-26 1998-04-01 Ciba Geigy Ag Procedimiento para la obtencion de amidinohidrazonas biciclicas.
US5424449A (en) * 1994-10-28 1995-06-13 Olin Corporation Process for the preparation of 5-aminotetrazole
US5850840A (en) * 1995-11-15 1998-12-22 Alteon Inc. Methods for measurement and treatment predicated on the presence of advanced glycosylation endproducts in tobacco and its combustion byproducts
US6110968A (en) * 1995-12-26 2000-08-29 The Picower Institute For Medical Research Methods for treatment predicated on the presence of advanced glycosylation endproducts in tobacco and its combustion byproducts
US5877217A (en) * 1995-12-26 1999-03-02 Alteon Inc. N-acylaminoalkyl-hydrazinecarboximidamides
AT405180B (de) * 1997-04-01 1999-06-25 Biochemie Gmbh Neue derivate von substituierten 3-cephem-4-carbonsäurederivaten und verfahren zu deren herstellung
US6693095B2 (en) 1997-04-01 2004-02-17 Biochemie Gesellschaft M.B.H. Antibacterial substituted 7-acylamino-3-(methylhydrazono) methyl-cephalosporins and intermediates
ES2203955T3 (es) * 1997-04-01 2004-04-16 Biochemie Gesellschaft M.B.H. 7-acilamino-3-(metilhidrazono)metil-cefalosporinas sustituidas antibacterianas y productos intermedios.
FR2771409B1 (fr) * 1997-11-21 2000-01-14 Oreal Nouveaux composes azoiques, utilisation pour la teinture, compositions les contenant et procedes de teinture
US6883592B2 (en) 1998-11-04 2005-04-26 Zalman Tech Co., Ltd. Heatsink for electronic component
US7180758B2 (en) 1999-07-22 2007-02-20 Mks Instruments, Inc. Class E amplifier with inductive clamp
FR2804428B1 (fr) * 2000-01-27 2002-03-22 Oreal Nouvelles bases d'oxydation a chaine guanidine, leur procede de preparation, leur utilisation pour la teinture d'oxydation des fibres keratiniques, compositions tinctoriales et procedes de teinture
ITRM20020625A1 (it) * 2002-12-17 2004-06-18 Sigma Tau Ind Farmaceuti Derivati di guanidine variamente sostituite, loro uso come medicamenti ad attivita' antidiabetica e/o antiobesita'.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE663481A (en, 2012) * 1964-05-05
GB1274668A (en) * 1968-06-10 1972-05-17 Ici Ltd Pesticidal compositions comprising aminoguanidines
US3803324A (en) * 1968-07-09 1974-04-09 Boehringer Mannheim Gmbh Amino-guanidine derivatives useful for regulating blood pressure
DE1768867C3 (de) * 1968-07-09 1973-12-20 Boehringer Mannheim Gmbh, 6800 Mannheim Aminoguanidin-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung von Arzneimitteln
DE1939738A1 (de) * 1969-08-05 1971-02-18 Boehringer Mannheim Gmbh Aminoguanidine und Verfahren zur Herstellung derselben
NL7315350A (nl) * 1973-11-09 1975-05-13 Akzo Nv Nieuwe aminoguanidine verbindingen.

Also Published As

Publication number Publication date
DK164155C (da) 1992-10-12
PL250892A1 (en) 1985-12-17
PL255440A1 (en) 1986-07-01
FI844909A0 (fi) 1984-12-12
DK164155B (da) 1992-05-18
PL140594B1 (en) 1987-05-30
PL142626B1 (en) 1987-11-30
KR870001105B1 (ko) 1987-06-08
NO159528C (no) 1989-01-11
US4731383A (en) 1988-03-15
BG60757B2 (bg) 1996-02-29
DK595484D0 (da) 1984-12-12
NO159528B (no) 1988-10-03
GB2151617B (en) 1987-06-10
SE462847B (sv) 1990-09-10
DE3445339C2 (en, 2012) 1989-12-14
IL73811A (en) 1988-12-30
FR2556343B1 (fr) 1988-03-04
NL193539C (nl) 2000-01-04
KR850004585A (ko) 1985-07-25
NL193539B (nl) 1999-09-01
BE901239A (fr) 1985-06-10
SE8406302D0 (sv) 1984-12-12
DD228246A5 (de) 1985-10-09
BG44374A3 (en) 1988-11-15
BG42355A3 (en) 1987-11-14
FI79527B (fi) 1989-09-29
HUT36089A (en) 1985-08-28
SE8406302L (sv) 1985-06-13
FI844909L (fi) 1985-06-13
JPH0226629B2 (en, 2012) 1990-06-12
FI79527C (fi) 1990-01-10
AT394192B (de) 1992-02-10
ATA392384A (de) 1991-08-15
DE3445339A1 (de) 1985-06-13
FR2556343A1 (fr) 1985-06-14
CH664955A5 (de) 1988-04-15
HU190639B (en) 1986-09-29
NO844978L (no) 1985-06-13
SU1498383A3 (ru) 1989-07-30
CA1237129A (en) 1988-05-24
SU1340583A3 (ru) 1987-09-23
IL73811A0 (en) 1985-03-31
GB2151617A (en) 1985-07-24
GB8431312D0 (en) 1985-01-23
NL8403779A (nl) 1985-07-01
DK595484A (da) 1985-06-13

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