JPH0757751B2 - トランス−６−〔２−（３−または４−カルボキサミド置換ピロ−ル−１−イル）アルキル〕−４−ヒドロキシピラン−２−オン - Google Patents

トランス−６−〔２−（３−または４−カルボキサミド置換ピロ−ル−１−イル）アルキル〕−４−ヒドロキシピラン−２−オン

Info

Publication number
JPH0757751B2
JPH0757751B2 JP62131931A JP13193187A JPH0757751B2 JP H0757751 B2 JPH0757751 B2 JP H0757751B2 JP 62131931 A JP62131931 A JP 62131931A JP 13193187 A JP13193187 A JP 13193187A JP H0757751 B2 JPH0757751 B2 JP H0757751B2
Authority
JP
Japan
Prior art keywords
carbon atoms
alkyl
phenyl
trifluoromethyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP62131931A
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English (en)
Japanese (ja)
Other versions
JPS62289577A (ja
Inventor
ブルース・デイー・ロス
Original Assignee
ワ−ナ−−ランバ−ト・コンパニ−
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25352470&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH0757751(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ワ−ナ−−ランバ−ト・コンパニ− filed Critical ワ−ナ−−ランバ−ト・コンパニ−
Publication of JPS62289577A publication Critical patent/JPS62289577A/ja
Publication of JPH0757751B2 publication Critical patent/JPH0757751B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
JP62131931A 1986-05-30 1987-05-29 トランス−６−〔２−（３−または４−カルボキサミド置換ピロ−ル−１−イル）アルキル〕−４−ヒドロキシピラン−２−オン Expired - Lifetime JPH0757751B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/868,867 US4681893A (en) 1986-05-30 1986-05-30 Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
US868867 1992-04-16

Publications (2)

Publication Number Publication Date
JPS62289577A JPS62289577A (ja) 1987-12-16
JPH0757751B2 true JPH0757751B2 (ja) 1995-06-21

Family

ID=25352470

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62131931A Expired - Lifetime JPH0757751B2 (ja) 1986-05-30 1987-05-29 トランス−６−〔２−（３−または４−カルボキサミド置換ピロ−ル−１−イル）アルキル〕−４−ヒドロキシピラン−２−オン

Country Status (23)

Country Link
US (1) US4681893A (da)
EP (1) EP0247633B1 (da)
JP (1) JPH0757751B2 (da)
KR (1) KR940001006B1 (da)
AT (1) ATE60602T1 (da)
AU (1) AU601981B2 (da)
CA (1) CA1268768A (da)
DE (2) DE3767770D1 (da)
DK (1) DK171588B1 (da)
ES (1) ES2019899T4 (da)
FI (1) FI88617C (da)
GR (1) GR3001415T3 (da)
HK (1) HK119493A (da)
IE (1) IE60014B1 (da)
LU (1) LU90147I2 (da)
MX (1) MX9203095A (da)
NL (1) NL970034I2 (da)
NO (2) NO168645C (da)
NZ (1) NZ220409A (da)
PH (2) PH24661A (da)
PT (1) PT84975B (da)
SA (1) SA99200199A (da)
ZA (1) ZA873438B (da)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008102563A1 (ja) 2007-02-23 2008-08-28 Next21 K.K. 血管攣縮の治療剤又は予防剤
JP2012520280A (ja) * 2009-03-10 2012-09-06 レデックス・ファーマ・リミテッド アトルバスタチンラクトールの薬物としての使用

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* Cited by examiner, † Cited by third party
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