JPH0575731B2 - - Google Patents
Info
- Publication number
- JPH0575731B2 JPH0575731B2 JP63244691A JP24469188A JPH0575731B2 JP H0575731 B2 JPH0575731 B2 JP H0575731B2 JP 63244691 A JP63244691 A JP 63244691A JP 24469188 A JP24469188 A JP 24469188A JP H0575731 B2 JPH0575731 B2 JP H0575731B2
- Authority
- JP
- Japan
- Prior art keywords
- tumor
- acid
- pyridine
- cell wall
- microorganism
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/5555—Muramyl dipeptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
- A61K2039/55594—Adjuvants of undefined constitution from bacteria
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/102,909 US4877611A (en) | 1986-04-15 | 1987-09-30 | Vaccine containing tumor antigens and adjuvants |
| US102909 | 1987-09-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01163130A JPH01163130A (ja) | 1989-06-27 |
| JPH0575731B2 true JPH0575731B2 (enExample) | 1993-10-21 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63244691A Granted JPH01163130A (ja) | 1987-09-30 | 1988-09-30 | 腫瘍抗原およびアジュバントを含有するワクチン |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4877611A (enExample) |
| JP (1) | JPH01163130A (enExample) |
| BE (1) | BE1001634A4 (enExample) |
| CA (1) | CA1333152C (enExample) |
| CH (1) | CH678492A5 (enExample) |
| DE (1) | DE3833319A1 (enExample) |
| FR (1) | FR2620941B1 (enExample) |
| GB (1) | GB2210557B (enExample) |
| IT (1) | IT1226861B (enExample) |
| NL (1) | NL8802393A (enExample) |
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| FR2160326B1 (enExample) * | 1971-11-19 | 1975-02-07 | Anvar | |
| US4338334A (en) * | 1977-12-29 | 1982-07-06 | Merck & Co., Inc. | 1-[4-(4-Sulfanilyl)phenyl] urea and derivatives in compositions and methods of treating rheumatoid arthritis and immune complex diseases |
| US4307229A (en) * | 1979-11-07 | 1981-12-22 | Avraham Liav | 6,6'-Diesters of trehalose and process for the synthesis thereof |
| US4436728A (en) * | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
| US4436727A (en) * | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
| US4505903A (en) * | 1982-06-30 | 1985-03-19 | Ribi Immunochem Research, Inc. | Pyridine soluble extract of a microorganism |
| US4606918A (en) * | 1983-08-22 | 1986-08-19 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
| US4663306A (en) * | 1983-09-23 | 1987-05-05 | Ribi Immunochem Research, Inc. | Pyridine-soluble extract-refined detoxified endotoxin composition and use |
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1987
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- 1988-09-29 NL NL8802393A patent/NL8802393A/nl active Search and Examination
- 1988-09-30 BE BE8801122A patent/BE1001634A4/fr not_active IP Right Cessation
- 1988-09-30 CH CH3632/88A patent/CH678492A5/de not_active IP Right Cessation
- 1988-09-30 JP JP63244691A patent/JPH01163130A/ja active Granted
- 1988-09-30 IT IT8822145A patent/IT1226861B/it active
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- 1988-09-30 DE DE3833319A patent/DE3833319A1/de active Granted
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| US4877611A (en) | 1989-10-31 |
| JPH01163130A (ja) | 1989-06-27 |
| GB2210557B (en) | 1991-11-13 |
| DE3833319C2 (enExample) | 1992-06-11 |
| GB8822749D0 (en) | 1988-11-02 |
| DE3833319A1 (de) | 1989-04-13 |
| CH678492A5 (enExample) | 1991-09-30 |
| FR2620941A1 (fr) | 1989-03-31 |
| IT1226861B (it) | 1991-02-19 |
| IT8822145A0 (it) | 1988-09-30 |
| FR2620941B1 (fr) | 1990-08-10 |
| NL8802393A (nl) | 1989-04-17 |
| CA1333152C (en) | 1994-11-22 |
| BE1001634A4 (fr) | 1990-01-02 |
| GB2210557A (en) | 1989-06-14 |
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