JP7075399B2 - Ｒｅｔキナーゼ阻害剤としての置換ピラゾロ［１，５－ａ］ピリジン化合物 - Google Patents
Ｒｅｔキナーゼ阻害剤としての置換ピラゾロ［１，５－ａ］ピリジン化合物 Download PDFInfo
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- JP7075399B2 JP7075399B2 JP2019519331A JP2019519331A JP7075399B2 JP 7075399 B2 JP7075399 B2 JP 7075399B2 JP 2019519331 A JP2019519331 A JP 2019519331A JP 2019519331 A JP2019519331 A JP 2019519331A JP 7075399 B2 JP7075399 B2 JP 7075399B2
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| US201762447849P | 2017-01-18 | 2017-01-18 | |
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| US201762491180P | 2017-04-27 | 2017-04-27 | |
| US62/491,180 | 2017-04-27 | ||
| US201762531690P | 2017-07-12 | 2017-07-12 | |
| US62/531,690 | 2017-07-12 | ||
| US201762566030P | 2017-09-29 | 2017-09-29 | |
| US62/566,030 | 2017-09-29 | ||
| PCT/US2017/055993 WO2018071454A1 (en) | 2016-10-10 | 2017-10-10 | Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors |
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| JP2019533670A JP2019533670A (ja) | 2019-11-21 |
| JP2019533670A5 JP2019533670A5 (enExample) | 2020-11-12 |
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| PL3322706T3 (pl) | 2015-07-16 | 2021-07-19 | Array Biopharma, Inc. | Podstawione związki pirazolo[1,5-a]pirydynowe jako inhibitory kinazy ret |
| RS65069B1 (sr) | 2015-11-02 | 2024-02-29 | Blueprint Medicines Corp | Inhibitori ret-a |
| JOP20190077A1 (ar) | 2016-10-10 | 2019-04-09 | Array Biopharma Inc | مركبات بيرازولو [1، 5-a]بيريدين بها استبدال كمثبطات كيناز ret |
| TWI704148B (zh) * | 2016-10-10 | 2020-09-11 | 美商亞雷生物製藥股份有限公司 | 作為ｒｅｔ激酶抑制劑之經取代吡唑并[1,5-a]吡啶化合物 |
| JP6990702B2 (ja) * | 2016-11-18 | 2022-01-13 | インテグレーティブ リサーチ ラボラトリーズ スウェーデン アーベー | 皮質カテコールアミン作動性神経伝達のモジュレーターとして有用な新規アゼチジン誘導体 |
| US11168090B2 (en) | 2017-01-18 | 2021-11-09 | Array Biopharma Inc. | Substituted pyrazolo[1,5-a]pyrazines as RET kinase inhibitors |
| TWI791053B (zh) * | 2017-10-10 | 2023-02-01 | 美商亞雷生物製藥股份有限公司 | 6-(2-羥基-2-甲基丙氧基)-4-(6-(6-((6-甲氧基吡啶-3-基)甲基)-3,6-二氮雜雙環[3.1.1]庚-3-基)吡啶-3-基)吡唑并[1,5-a]吡啶-3-甲腈之結晶形式及其醫藥組合物 |
| CA3087578C (en) | 2018-01-18 | 2023-08-08 | Array Biopharma Inc. | Substituted pyrazolo[3,4-d]pyrimidine compounds as ret kinase inhibitors |
| EP3740486A1 (en) | 2018-01-18 | 2020-11-25 | Array Biopharma, Inc. | Substituted pyrazolyl[4,3-c]pyridinecompounds as ret kinase inhibitors |
| EP3740491A1 (en) | 2018-01-18 | 2020-11-25 | Array Biopharma, Inc. | Substituted pyrrolo[2,3-d]pyrimidines compounds as ret kinase inhibitors |
| FI3773589T3 (fi) | 2018-04-03 | 2024-02-01 | Blueprint Medicines Corp | Ret-estäjä käytettäväksi ret-muunnoksen sisältävän syövän hoidossa |
| WO2020055672A1 (en) | 2018-09-10 | 2020-03-19 | Array Biopharma Inc. | Fused heterocyclic compounds as ret kinase inhibitors |
| EP3856743A4 (en) * | 2018-09-27 | 2022-06-15 | Fochon Pharmaceuticals, Ltd. | SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE AND [1,2,4]TRIAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS |
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