JP5649825B2 - 安定化させたｐ５３ペプチドおよびその使用法 - Google Patents

安定化させたｐ５３ペプチドおよびその使用法 Download PDF

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JP5649825B2
JP5649825B2 JP2009548441A JP2009548441A JP5649825B2 JP 5649825 B2 JP5649825 B2 JP 5649825B2 JP 2009548441 A JP2009548441 A JP 2009548441A JP 2009548441 A JP2009548441 A JP 2009548441A JP 5649825 B2 JP5649825 B2 JP 5649825B2
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modified polypeptide
amino acid
acceptable salt
pharmaceutically acceptable
independently
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JP2010518017A5 (enExample
JP2010518017A (ja
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フェデリコ バーナル
フェデリコ バーナル
ローレン ディー． ワレンスキー
ローレン ディー． ワレンスキー
グレゴリー エル． ヴァーダイン
グレゴリー エル． ヴァーダイン
スタンレイ コースメイヤー
スタンレイ コースメイヤー
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Harvard University
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Harvard University
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2009548441A 2007-01-31 2008-01-31 安定化させたｐ５３ペプチドおよびその使用法 Active JP5649825B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88752607P 2007-01-31 2007-01-31
US60/887,526 2007-01-31
PCT/US2008/052580 WO2008095063A1 (en) 2007-01-31 2008-01-31 Stabilized p53 peptides and uses thereof

Related Child Applications (1)

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JP2014137588A Division JP2014224121A (ja) 2007-01-31 2014-07-03 安定化させたｐ５３ペプチドおよびその使用法

Publications (3)

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JP2010518017A JP2010518017A (ja) 2010-05-27
JP2010518017A5 JP2010518017A5 (enExample) 2011-03-24
JP5649825B2 true JP5649825B2 (ja) 2015-01-07

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JP2009548441A Active JP5649825B2 (ja) 2007-01-31 2008-01-31 安定化させたｐ５３ペプチドおよびその使用法
JP2014137588A Pending JP2014224121A (ja) 2007-01-31 2014-07-03 安定化させたｐ５３ペプチドおよびその使用法
JP2016145368A Active JP6775344B2 (ja) 2007-01-31 2016-07-25 安定化させたｐ５３ペプチドおよびその使用法

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JP2014137588A Pending JP2014224121A (ja) 2007-01-31 2014-07-03 安定化させたｐ５３ペプチドおよびその使用法
JP2016145368A Active JP6775344B2 (ja) 2007-01-31 2016-07-25 安定化させたｐ５３ペプチドおよびその使用法

Country Status (10)

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US (3) US8889632B2 (enExample)
EP (2) EP2118123B1 (enExample)
JP (3) JP5649825B2 (enExample)
AU (1) AU2008210434C8 (enExample)
CA (2) CA2939778C (enExample)
DK (1) DK2118123T3 (enExample)
ES (1) ES2558928T3 (enExample)
PL (1) PL2118123T3 (enExample)
PT (1) PT2118123E (enExample)
WO (1) WO2008095063A1 (enExample)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
US10794831B2 (en) 2016-08-18 2020-10-06 Horiba, Ltd. Organic compound analyzer, organic compound analysis method, and program for organic compound analyzer

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