|
JPS59170313A
(ja)
|
1983-03-14 |
1984-09-26 |
Kurimoto Iron Works Ltd |
スクリ−ンゲ−ト
|
|
JPS6085739U
(ja)
|
1983-11-18 |
1985-06-13 |
クラリオン株式会社 |
テ−プレコ−ダにおけるピンチロ−ラ装置
|
|
JPS6243003U
(enExample)
|
1985-09-05 |
1987-03-14 |
|
|
|
JPH0314566A
(ja)
|
1989-06-09 |
1991-01-23 |
Sankyo Co Ltd |
ベンズイミダゾール誘導体
|
|
US5244912A
(en)
|
1991-03-28 |
1993-09-14 |
Eli Lilly And Company |
6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
|
|
FR2710915B1
(fr)
|
1993-10-04 |
1995-11-24 |
Synthelabo |
Dérivés de pipéridine, leur préparation et leur utilisation en thérapeutique.
|
|
GB9410469D0
(en)
|
1994-05-25 |
1994-07-13 |
Erba Farmitalia |
Imidazolylalkyl derivatives of imidazo (5,1-c) (1,4) benzoxazin-1-one and process for their preparation
|
|
FR2731708B1
(fr)
|
1995-03-13 |
1997-04-30 |
Synthelabo |
Derives de piperidine, leur procede de preparation et leur application en therapeutique
|
|
FR2747678B1
(fr)
|
1996-04-22 |
1998-05-22 |
Synthelabo |
Composes derives d'imidazobenzoxazine, leurs procedes de preparation et leurs utilisations en therapeutique
|
|
US6287693B1
(en)
|
1998-02-25 |
2001-09-11 |
John Claude Savoir |
Stable shaped particles of crystalline organic compounds
|
|
DE60115872T2
(de)
|
2000-04-21 |
2006-07-13 |
Pharmacia & Upjohn Co. Llc, Kalamazoo |
Cabergolin zur behandlung von fibromyalgie und chronic-fatigue-syndrom
|
|
EP1294358B1
(en)
|
2000-06-28 |
2004-08-18 |
Smithkline Beecham Plc |
Wet milling process
|
|
FR2816619B1
(fr)
|
2000-11-15 |
2003-01-31 |
Sanofi Synthelabo |
Derives de benzimidazole, leur preparation et leur application en therapeutique
|
|
CN1446218A
(zh)
|
2000-08-08 |
2003-10-01 |
圣诺菲-合成实验室公司 |
苯并咪唑衍生物,它们的制备方法以及它们的治疗应用
|
|
US6919334B2
(en)
|
2002-09-12 |
2005-07-19 |
Wyeth |
Antidepressant azaheterocyclymethyl derivatives of 4,5-dihydroimidazo[1,4,5-de][1,4]benzoxazine
|
|
MXPA05005425A
(es)
|
2002-11-22 |
2005-11-23 |
Japan Tobacco Inc |
Heterociclos que contienen nitrogeno, biciclicos, fusionados.
|
|
EP1462103A1
(en)
|
2003-03-25 |
2004-09-29 |
Faust Pharmaceuticals |
NO donors, combination products and uses as modulators of neurotransmitter release
|
|
WO2005080334A1
(ja)
|
2004-02-23 |
2005-09-01 |
Dainippon Sumitomo Pharma Co., Ltd. |
新規へテロ環化合物
|
|
JP4790703B2
(ja)
|
2004-04-07 |
2011-10-12 |
武田薬品工業株式会社 |
環式化合物
|
|
US7713954B2
(en)
|
2004-09-30 |
2010-05-11 |
Roche Palo Alto Llc |
Compositions and methods for treating cognitive disorders
|
|
DE102005011058A1
(de)
|
2005-03-10 |
2006-09-14 |
Merck Patent Gmbh |
Substituierte Tetrahydro-pyrrolo-chinolinderivate
|
|
WO2006124874A2
(en)
|
2005-05-12 |
2006-11-23 |
Kalypsys, Inc. |
Inhibitors of b-raf kinase
|
|
WO2006129623A1
(ja)
|
2005-05-30 |
2006-12-07 |
Mitsubishi Tanabe Pharma Corporation |
チエノトリアゾロジアゼピン化合物及びその医薬としての用途
|
|
US20080318999A1
(en)
|
2005-08-05 |
2008-12-25 |
Methvin Isaac |
Tricyclic Benzimidazoles and Their Use as Metabotropic Glutamate Receptor Modulators
|
|
EP2147310A4
(en)
|
2007-04-27 |
2010-09-08 |
Univ Rochester |
COMPOSITIONS AND METHODS OF INHIBITING G-PROTEIN SIGNALING
|
|
US8633186B2
(en)
|
2007-06-08 |
2014-01-21 |
Senomyx Inc. |
Modulation of chemosensory receptors and ligands associated therewith
|
|
US7928111B2
(en)
|
2007-06-08 |
2011-04-19 |
Senomyx, Inc. |
Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
|
|
US9603848B2
(en)
|
2007-06-08 |
2017-03-28 |
Senomyx, Inc. |
Modulation of chemosensory receptors and ligands associated therewith
|
|
WO2009020559A2
(en)
|
2007-08-03 |
2009-02-12 |
The J. David Gladstone Institutes |
Agents that inhibit p-tefb interactions and methods of use thereof
|
|
CN101910182B
(zh)
|
2007-12-28 |
2013-07-17 |
田边三菱制药株式会社 |
抗癌剂
|
|
DE102008052618A1
(de)
|
2008-10-21 |
2010-04-22 |
Henkel Ag & Co. Kgaa |
Tricyclische Aldehyde und C,H-acide Verbindungen
|
|
WO2010111626A2
(en)
|
2009-03-27 |
2010-09-30 |
Takeda Pharmaceutical Company Limited |
Poly (adp-ribose) polymerase (parp) inhibitors
|
|
TW201103941A
(en)
|
2009-06-10 |
2011-02-01 |
Janssen Pharmaceutica Nv |
Benzimidazole derivatives useful as TRPM8 channel modulators
|
|
TW201105681A
(en)
|
2009-06-10 |
2011-02-16 |
Janssen Pharmaceutica Nv |
Benzimidazole derivatives useful as TRPM8 channel modulators
|
|
WO2011024987A1
(ja)
|
2009-08-31 |
2011-03-03 |
塩野義製薬株式会社 |
芳香族縮合へテロ環誘導体およびそれらを含有する医薬組成物
|
|
GB0919431D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB0919423D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB0919426D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB0919432D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Use
|
|
ES2652304T3
(es)
|
2009-11-05 |
2018-02-01 |
Glaxosmithkline Llc |
Compuesto de benzodiacepina novedoso
|
|
EP3050885B1
(en)
|
2009-11-05 |
2017-10-18 |
GlaxoSmithKline LLC |
Benzodiazepine bromodomain inhibitor
|
|
WO2011054851A1
(en)
|
2009-11-05 |
2011-05-12 |
Glaxosmithkline Llc |
Novel process
|
|
GB0919434D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
WO2011133722A2
(en)
|
2010-04-23 |
2011-10-27 |
Kineta, Inc. |
Anti-viral compounds
|
|
CN103119160B
(zh)
|
2010-05-14 |
2016-06-01 |
达那-法伯癌症研究所 |
用于调节代谢的组合物和方法
|
|
WO2011143657A1
(en)
|
2010-05-14 |
2011-11-17 |
Dana-Farber Cancer Institute, Inc. |
Male contraceptive compositions and methods of use
|
|
HUE031073T2
(en)
|
2010-05-14 |
2017-06-28 |
Dana Farber Cancer Inst Inc |
Thieno triazolo-diazepine compounds for the treatment of neoplasia
|
|
CA2799403C
(en)
|
2010-05-14 |
2020-01-21 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating leukemia
|
|
WO2011161031A1
(en)
|
2010-06-22 |
2011-12-29 |
Glaxosmithkline Llc |
Benzotriazolodiazepine compounds inhibitors of bromodomains
|
|
AR084070A1
(es)
|
2010-12-02 |
2013-04-17 |
Constellation Pharmaceuticals Inc |
Inhibidores del bromodominio y usos de los mismos
|
|
WO2012075456A1
(en)
|
2010-12-02 |
2012-06-07 |
Constellation Pharmaceuticals |
Bromodomain inhibitors and uses thereof
|
|
US8653089B2
(en)
|
2011-02-09 |
2014-02-18 |
F. Hoffmann-La Roche Ag |
Heterocyclic compounds and methods of use
|
|
AU2012220620A1
(en)
|
2011-02-23 |
2013-10-03 |
Icahn School Of Medicine At Mount Sinai |
Inhibitors of bromodomains as modulators of gene expression
|
|
RU2013143747A
(ru)
|
2011-03-21 |
2015-04-27 |
Ф. Хоффманн-Ля Рош Аг |
Соединения бензоксазепина, селективные в отношении pi3k p110 дельта и способы их применения
|
|
GB201106743D0
(en)
|
2011-04-21 |
2011-06-01 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB201106750D0
(en)
|
2011-04-21 |
2011-06-01 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB201106799D0
(en)
|
2011-04-21 |
2011-06-01 |
Glaxosmithkline Llc |
Novel compounds
|
|
EP2705039B1
(en)
|
2011-05-04 |
2017-07-26 |
Constellation Pharmaceuticals, Inc. |
Bromodomain inhibitors and uses thereof
|
|
GB201107325D0
(en)
|
2011-05-04 |
2011-06-15 |
Glaxosmithkline Llc |
Novel compounds
|
|
EP2721031B1
(en)
|
2011-06-17 |
2016-01-20 |
Constellation Pharmaceuticals, Inc. |
Bromodomain inhibitors and uses thereof
|
|
EP2723338A2
(en)
|
2011-06-24 |
2014-04-30 |
The Trustees of Stevens Institute of Technology |
Selective inhibitors of histone deacetylase isoform 6 and methods thereof
|
|
JP2013010719A
(ja)
|
2011-06-30 |
2013-01-17 |
Dainippon Sumitomo Pharma Co Ltd |
ベンズイミダゾロンおよびオキシインドール誘導体ならびにそれらの医薬用途
|
|
JP2014524409A
(ja)
|
2011-07-29 |
2014-09-22 |
ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア |
Ｈｉｖの治療のための組成物および方法
|
|
GB201114103D0
(en)
|
2011-08-17 |
2011-09-28 |
Glaxosmithkline Llc |
Novel compounds
|
|
WO2013027168A1
(en)
|
2011-08-22 |
2013-02-28 |
Pfizer Inc. |
Novel heterocyclic compounds as bromodomain inhibitors
|
|
WO2013033270A2
(en)
|
2011-08-29 |
2013-03-07 |
Coferon, Inc. |
Bromodomain ligands capable of dimerizing in an aqueous solution, and methods of using same
|
|
WO2013033269A1
(en)
|
2011-08-29 |
2013-03-07 |
Coferon, Inc. |
Bioorthogonal monomers capable of dimerizing and targeting bromodomains and methods of using same
|
|
AU2012303954B2
(en)
|
2011-08-31 |
2017-06-22 |
Otsuka Pharmaceutical Co., Ltd. |
Quinolone compound
|
|
DE102011082013A1
(de)
|
2011-09-01 |
2013-03-07 |
Bayer Pharma AG |
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
|
|
ES2632443T3
(es)
|
2011-09-22 |
2017-09-13 |
Viiv Healthcare Uk Limited |
Compuestos de pirrolopiridinona y procedimientos de tratamiento del VIH
|
|
WO2013044511A1
(zh)
|
2011-09-30 |
2013-04-04 |
沈阳蓝桑医药生物技术研发有限公司 |
含有瑞利格内酯的药物组合物及其应用
|
|
WO2013060636A1
(en)
|
2011-10-25 |
2013-05-02 |
Sanofi |
6-(4-hydroxy-phenyl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
JP5992049B2
(ja)
|
2011-11-01 |
2016-09-14 |
レスバーロジックス コーポレイション |
置換されたキナゾリノンのための経口速放性製剤
|
|
WO2013097052A1
(en)
|
2011-12-30 |
2013-07-04 |
Abbott Laboratories |
Bromodomain inhibitors
|
|
US20150133434A1
(en)
|
2012-03-28 |
2015-05-14 |
The J. David Gladstone Institutes |
Compositions and Methods for Reactivating Latent Immunodeficiency Virus
|
|
US20130281399A1
(en)
|
2012-04-19 |
2013-10-24 |
Rvx Therapeutics Inc. |
Treatment of diseases by epigenetic regulation
|
|
US20130281396A1
(en)
|
2012-04-19 |
2013-10-24 |
Rvx Therapeutics Inc. |
Treatment of diseases by epigenetic regulation
|
|
US20130281398A1
(en)
|
2012-04-19 |
2013-10-24 |
Rvx Therapeutics Inc. |
Treatment of diseases by epigenetic regulation
|
|
US20130281397A1
(en)
|
2012-04-19 |
2013-10-24 |
Rvx Therapeutics Inc. |
Treatment of diseases by epigenetic regulation
|
|
HK1206744A1
(en)
|
2012-04-20 |
2016-01-15 |
Abbvie Inc. |
Isoindolone derivatives
|
|
TWI602820B
(zh)
|
2012-06-06 |
2017-10-21 |
星宿藥物公司 |
溴域抑制劑及其用途
|
|
EP2864336B1
(en)
|
2012-06-06 |
2016-11-23 |
Constellation Pharmaceuticals, Inc. |
Benzo[b]isoxazoloazepine bromodomain inhibitors and uses thereof
|
|
MX2014015156A
(es)
|
2012-06-12 |
2015-08-06 |
Abbvie Inc |
Derivados de piridinona y piridazinona.
|
|
EP2863923B1
(en)
|
2012-06-25 |
2019-05-08 |
Oncoethix GmbH |
Thienotriazolodiazepine compounds for the treatment of lymphomas
|
|
US9610332B2
(en)
|
2012-07-18 |
2017-04-04 |
Massachusetts Institute Of Technology |
Compositions and methods for modulating BRD4 bioactivity
|
|
PE20150729A1
(es)
|
2012-08-16 |
2015-06-14 |
Bayer Pharma AG |
2,3-benzodiazepines
|
|
ES2653990T3
(es)
|
2012-08-16 |
2018-02-09 |
Glaxosmithkline Llc |
Benzodiazepinas para tratamiento del cáncer de pulmón de células pequeñas
|
|
WO2014048945A1
(de)
|
2012-09-28 |
2014-04-03 |
Bayer Pharma Aktiengesellschaft |
Bet-proteininhibitorische 5-aryl-triazolo-azepine
|
|
MX2015003771A
(es)
|
2012-09-28 |
2016-03-04 |
Oncoethix Gmbh |
Formulacion farmaceutica que contiene compuestos de tienotriazolodiazepina.
|
|
SI2917181T1
(sl)
|
2012-11-09 |
2020-01-31 |
Mmv Medicines For Malaria Venture |
Heteroarilni derivati in uporabe le-teh
|
|
US9422290B2
(en)
|
2012-11-13 |
2016-08-23 |
Boehringer Ingelheim International Gmbh |
Triazolopyridazine
|
|
EP2920183B1
(en)
|
2012-11-14 |
2017-03-08 |
Glaxosmithkline LLC |
Thieno[3,2-c]pyridin-4(5h)-ones as bet inhibitors
|
|
WO2014080290A2
(en)
|
2012-11-21 |
2014-05-30 |
Rvx Therapeutics Inc. |
Cyclic amines as bromodomain inhibitors
|
|
WO2014080291A2
(en)
|
2012-11-21 |
2014-05-30 |
Rvx Therapeutics Inc. |
Biaryl derivatives as bromodomain inhibitors
|
|
WO2014095775A1
(de)
|
2012-12-20 |
2014-06-26 |
Bayer Pharma Aktiengesellschaft |
Bet-proteininhibitorische dihydrochinoxalinone
|
|
JP2016504990A
(ja)
|
2012-12-20 |
2016-02-18 |
バイエル ファーマ アクチエンゲゼルシャフト |
Ｂｅｔタンパク質抑制性ジヒドロピリドピラジノン
|
|
AU2013365926B9
(en)
|
2012-12-21 |
2019-01-17 |
Zenith Epigenetics Ltd. |
Novel heterocyclic compounds as bromodomain inhibitors
|
|
WO2014128655A1
(en)
|
2013-02-25 |
2014-08-28 |
Aurigene Discovery Technologies Limited |
Substituted imidazo[4,5-c]quinoline derivatives as bromodomain inhibitors
|
|
US9492460B2
(en)
|
2013-02-27 |
2016-11-15 |
Bristol-Myers Squibb Company |
Carbazole compounds useful as bromodomain inhibitors
|
|
CN105189488B
(zh)
|
2013-02-27 |
2018-07-24 |
百时美施贵宝公司 |
用作溴区结构域抑制剂的咔唑化合物
|
|
CA2904048A1
(en)
|
2013-03-11 |
2014-10-09 |
Abbvie Inc. |
Bromodomain inhibitors
|
|
BR112015022674A2
(pt)
|
2013-03-11 |
2017-07-18 |
Abbvie Inc |
inibidores de bromodomínio
|
|
CN105377851B
(zh)
|
2013-03-11 |
2018-07-20 |
密执安州立大学董事会 |
Bet布罗莫结构域抑制剂和使用这些抑制剂的治疗方法
|
|
US9493411B2
(en)
|
2013-03-12 |
2016-11-15 |
Abbvie Inc. |
Pyrrole-3-carboxamide bromodomain inhibitors
|
|
JP6419735B2
(ja)
|
2013-03-12 |
2018-11-07 |
アッヴィ・インコーポレイテッド |
四環系ブロモドメイン阻害剤
|
|
KR20150126696A
(ko)
|
2013-03-12 |
2015-11-12 |
애브비 인코포레이티드 |
디하이드로-피롤로피리디논 브로모도메인 억제제
|
|
WO2014140077A1
(en)
|
2013-03-14 |
2014-09-18 |
Glaxosmithkline Intellectual Property (No.2) Limited |
Furopyridines as bromodomain inhibitors
|
|
WO2014159392A1
(en)
|
2013-03-14 |
2014-10-02 |
Dana-Farber Cancer Institute, Inc. |
Bromodomain binding reagents and uses thereof
|
|
BR112015022417A2
(pt)
|
2013-03-14 |
2017-07-18 |
Convergene Llc |
métodos e composições para inibição de proteínas contendo bromodomínio
|
|
ES2704048T3
(es)
|
2013-03-14 |
2019-03-14 |
Glaxosmithkline Ip No 2 Ltd |
Derivados de 1-acil-4-amino-1,2,3,4-tetrahidroquinolina-2,3-disustituida y su uso como inhibidores de bromodominio
|
|
RU2680100C9
(ru)
|
2013-03-15 |
2019-04-18 |
Плексксикон Инк. |
Гетероциклические соединения и их применения
|
|
US20160039842A1
(en)
|
2013-03-15 |
2016-02-11 |
Epigenetix, Inc. |
Oxazolo[5,4-c]quinolin-2-one compounds as bromodomain inhibitors
|
|
TWI719464B
(zh)
|
2013-03-15 |
2021-02-21 |
美商英塞特控股公司 |
作為bet蛋白抑制劑之三環雜環
|
|
US9199988B2
(en)
|
2013-03-27 |
2015-12-01 |
Boehringer Ingelheim International Gmbh |
Dihydroquinazolinone analogues
|
|
JP6370368B2
(ja)
|
2013-03-27 |
2018-08-08 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｂｒｄ４阻害剤としてのインドリノン類似体
|
|
TWI530499B
(zh)
|
2013-03-28 |
2016-04-21 |
吉李德科學股份有限公司 |
作為溴結構域（ｂｒｏｍｏｄｏｍａｉｎ）抑制劑之苯並咪唑酮衍生物類
|
|
US10435364B2
(en)
|
2013-04-17 |
2019-10-08 |
Albert Ludwigs Universität Freiburg |
Compounds for use as bromodomain inhibitors
|
|
WO2014173241A1
(en)
|
2013-04-26 |
2014-10-30 |
Beigene, Ltd. |
Substituted5-(3,5-dimethylisoxazol-4-yl)indoline-2-ones
|
|
TWI527811B
(zh)
|
2013-05-09 |
2016-04-01 |
吉李德科學股份有限公司 |
作爲溴結構域抑制劑的苯並咪唑衍生物
|
|
MX2015016344A
(es)
|
2013-05-27 |
2016-03-01 |
Novartis Ag |
Derivados de imidazo-pirrolidinona y su uso en el tratamiento de enfermedades.
|
|
US8975417B2
(en)
|
2013-05-27 |
2015-03-10 |
Novartis Ag |
Pyrazolopyrrolidine derivatives and their use in the treatment of disease
|
|
KR20160012195A
(ko)
|
2013-05-28 |
2016-02-02 |
노파르티스 아게 |
Bet 억제제로서의 피라졸로-피롤리딘-4-온 유도체 및 질환의 치료에서의 그의 용도
|
|
BR112015029353A2
(pt)
|
2013-05-28 |
2017-07-25 |
Novartis Ag |
derivados de pirazolo-pirrolidin-4-ona e seu uso no tratamento de doenças
|
|
ITMI20130991A1
(it)
|
2013-06-17 |
2014-12-18 |
Industrie De Nora Spa |
Sistema per la misurazione di correnti presenti sugli elettrodi in celle elettrolitiche interconnesse.
|
|
CA2915419A1
(en)
|
2013-06-17 |
2014-12-24 |
Bayer Pharma Aktiengesellschaft |
Substituted phenyl-2,3-benzodiazepines
|
|
ES2661437T3
(es)
|
2013-06-21 |
2018-04-02 |
Zenith Epigenetics Corp. |
Nuevos compuestos bicíclicos sustituidos como inhibidores de bromodominio
|
|
SI3010503T1
(sl)
|
2013-06-21 |
2020-07-31 |
Zenith Epigenetics Ltd. |
Novi biciklični inhibitorji bromodomene
|
|
AR096758A1
(es)
*
|
2013-06-28 |
2016-02-03 |
Abbvie Inc |
Inhibidores cristalinos de bromodominios
|
|
SG11201510678TA
(en)
|
2013-06-28 |
2016-01-28 |
Abbvie Inc |
Bromodomain inhibitors
|
|
JP2016523964A
(ja)
|
2013-07-08 |
2016-08-12 |
インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ |
Ｂｅｔタンパク質阻害剤としての三環式複素環
|
|
PL3022191T3
(pl)
|
2013-07-16 |
2017-08-31 |
Basf Se |
Chwastobójcze azyny
|
|
KR20160034379A
(ko)
|
2013-07-25 |
2016-03-29 |
다나-파버 캔서 인스티튜트 인크. |
전사 인자의 억제제 및 그의 용도
|
|
KR101672096B1
(ko)
|
2013-09-30 |
2016-11-02 |
주식회사 엘지화학 |
헤테로환 화합물 및 이를 포함하는 유기 발광 소자
|
|
PE20161065A1
(es)
|
2013-10-18 |
2016-11-19 |
Celgene Quanticel Res Inc |
Inhibidores de bromodominio
|
|
US20150148372A1
(en)
|
2013-11-26 |
2015-05-28 |
Incyte Corporation |
Bicyclic heterocycles as bet protein inhibitors
|
|
WO2015081203A1
(en)
|
2013-11-26 |
2015-06-04 |
Incyte Corporation |
Bicyclic heterocycles as bet protein inhibitors
|
|
WO2015081189A1
(en)
|
2013-11-26 |
2015-06-04 |
Incyte Corporation |
Bicyclic heterocycles as bet protein inhibitors
|
|
JP2016539970A
(ja)
|
2013-12-09 |
2016-12-22 |
アッヴィ・インコーポレイテッド |
ブロモドメイン阻害薬として有用なジヒドロピリジノンおよびジヒドロピリダジノン誘導体
|
|
US9309246B2
(en)
|
2013-12-19 |
2016-04-12 |
Incyte Corporation |
Tricyclic heterocycles as BET protein inhibitors
|
|
WO2015095445A1
(en)
|
2013-12-20 |
2015-06-25 |
Merck Sharp & Dohme Corp. |
Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
|
|
BR112016015311B1
(pt)
|
2014-01-09 |
2023-01-24 |
Orion Corporation |
Compostos derivados heterocíclicos bicíclicos, composição farmacêutica que compreende os mesmos e uso dos ditos compostos para tratar uma doença associada com bromodomínio
|
|
WO2015131005A1
(en)
|
2014-02-28 |
2015-09-03 |
The Regents Of The University Of Michigan |
9h-pyrimido[4,5-b]indoles and related analogs as bet bromodomain inhibitors
|
|
AU2015250900B9
(en)
|
2014-04-23 |
2019-03-21 |
Basf Se |
Diaminotriazine compounds as herbicides
|
|
KR20240134245A
(ko)
|
2014-04-23 |
2024-09-06 |
인사이트 홀딩스 코포레이션 |
BET 단백질의 저해제로서의 1H-피롤로[2,3-c]피리딘-7(6H)-온 및 피라졸로[3,4-c]피리딘-7(6H)-온
|
|
PL3134386T3
(pl)
|
2014-04-23 |
2020-11-16 |
Takeda Pharmaceutical Company Limited |
Pochodne izoindolin-1-onu jako dodatnia aktywność allosterycznego modulatora cholinergicznego receptora muskarynowego m1 do leczenia choroby alzheimera
|
|
KR20160145833A
(ko)
|
2014-05-02 |
2016-12-20 |
온코에틱스 게엠베하 |
티에노트리아졸로디아제핀 화합물을 사용한 급성 골수성 백혈병 및/또는 급성 림프아구성 백혈병의 치료 방법
|
|
WO2015168555A1
(en)
|
2014-05-02 |
2015-11-05 |
Oncoethix Sa |
Method of treating resistant non-hodgkin lymphoma, medulloblastoma, and/or alk+non-small cell lung cancer using thienotriazolodiazepine compounds
|
|
BR112016026046A8
(pt)
|
2014-05-08 |
2021-07-20 |
Oncoethix Gmbh |
uso de compostos de tienotriazolodiazepina
|
|
WO2015169953A1
(en)
|
2014-05-08 |
2015-11-12 |
Oncoethix Gmbh |
Method of treating glioma using thienotriazolodiazepine compounds
|
|
EP3148543B1
(en)
|
2014-05-30 |
2020-04-08 |
Icahn School of Medicine at Mount Sinai |
Small molecule transcription modulators of bromodomains
|
|
US9969747B2
(en)
|
2014-06-20 |
2018-05-15 |
Constellation Pharmaceuticals, Inc. |
Crystalline forms of 2-((4S)-6-(4-chlorophenyl)-1-methyl-4H-benzo[C]isoxazolo[4,5-e]azepin-4-yl)acetamide
|
|
US9861077B2
(en)
|
2014-07-11 |
2018-01-09 |
Jaan Aked-Hurditch |
Leash accessory
|
|
US9527864B2
(en)
|
2014-09-15 |
2016-12-27 |
Incyte Corporation |
Tricyclic heterocycles as BET protein inhibitors
|
|
HUE050706T2
(hu)
|
2014-10-24 |
2020-12-28 |
Bristol Myers Squibb Co |
Indol karboxamid vegyületek, amelyek hasznosak kináz inhibitorokként
|
|
MA40943A
(fr)
*
|
2014-11-10 |
2017-09-19 |
Constellation Pharmaceuticals Inc |
Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines
|
|
CA2974153A1
(en)
|
2015-02-03 |
2016-08-11 |
Trillium Therapeutics Inc. |
Fluorinated imidazo[4,5-c]quinoline derivatives as inhibitors of bromodomain containing proteins
|
|
WO2016186453A1
(en)
|
2015-05-20 |
2016-11-24 |
Kainos Medicine, Inc. |
Quinoline derivatives as bromodomain inhibitors
|
|
CA2987384A1
(en)
|
2015-05-29 |
2016-12-08 |
Shionogi & Co., Ltd. |
Nitrogen-containing tricyclic derivative having hiv replication inhibitory activity
|
|
CN105039258B
(zh)
|
2015-07-03 |
2018-04-17 |
北京大学 |
将非神经元细胞重编程为神经元样细胞的方法和组合物
|
|
US20170121347A1
(en)
|
2015-10-29 |
2017-05-04 |
Incyte Corporation |
Amorphous solid form of a bet protein inhibitor
|
|
CN105254635A
(zh)
|
2015-10-30 |
2016-01-20 |
中国药科大学 |
一类咪唑并吡嗪类化合物及其药物组合物和用途
|
|
US20170127985A1
(en)
|
2015-11-11 |
2017-05-11 |
Medtronic Minimed, Inc. |
Sensor set
|
|
CA3007168A1
(en)
|
2015-12-14 |
2017-06-22 |
Zenith Epigenetics Ltd. |
1h-imidazo[4,5-b]pyridinyl and 2-oxo-2,3-dihydro-1h-imidazo[4,5-b]pyridinyl heterocyclic bet bromodomain inhibitors
|
|
WO2017127930A1
(en)
|
2016-01-28 |
2017-08-03 |
Neomed Institute |
Substituted [1,2,4]triazolo[4,3-a]pyridines, their preparation and their use as pharmaceuticals
|
|
EP3412669A4
(en)
|
2016-02-05 |
2019-09-04 |
Chia Tai Tianqing Pharmaceutical Group Co.,Ltd |
TRICYCLIC COMPOUND FOR PROTEIN INHIBITOR CONTAINING BROMODOMAINE AND PREPARATION, PHARMACEUTICAL COMPOSITION AND USE THEREOF
|
|
EP4234554A3
(en)
|
2016-06-20 |
2023-12-27 |
Incyte Corporation |
Crystalline solid forms of a bet inhibitor
|
|
CN108069958A
(zh)
|
2016-11-10 |
2018-05-25 |
凯惠科技发展(上海)有限公司 |
一种含氮杂环类化合物、其制备方法、药物组合物及应用
|