|
JPS59170313A
(ja)
|
1983-03-14 |
1984-09-26 |
Kurimoto Iron Works Ltd |
スクリ−ンゲ−ト
|
|
JPS6085739U
(ja)
|
1983-11-18 |
1985-06-13 |
クラリオン株式会社 |
テ−プレコ−ダにおけるピンチロ−ラ装置
|
|
JPS6243003U
(enExample)
|
1985-09-05 |
1987-03-14 |
|
|
|
JPH0314566A
(ja)
|
1989-06-09 |
1991-01-23 |
Sankyo Co Ltd |
ベンズイミダゾール誘導体
|
|
US5244912A
(en)
|
1991-03-28 |
1993-09-14 |
Eli Lilly And Company |
6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
|
|
FR2710915B1
(fr)
|
1993-10-04 |
1995-11-24 |
Synthelabo |
Dérivés de pipéridine, leur préparation et leur utilisation en thérapeutique.
|
|
GB9410469D0
(en)
|
1994-05-25 |
1994-07-13 |
Erba Farmitalia |
Imidazolylalkyl derivatives of imidazo (5,1-c) (1,4) benzoxazin-1-one and process for their preparation
|
|
FR2731708B1
(fr)
|
1995-03-13 |
1997-04-30 |
Synthelabo |
Derives de piperidine, leur procede de preparation et leur application en therapeutique
|
|
FR2747678B1
(fr)
|
1996-04-22 |
1998-05-22 |
Synthelabo |
Composes derives d'imidazobenzoxazine, leurs procedes de preparation et leurs utilisations en therapeutique
|
|
US6287693B1
(en)
|
1998-02-25 |
2001-09-11 |
John Claude Savoir |
Stable shaped particles of crystalline organic compounds
|
|
NZ531172A
(en)
|
2000-04-21 |
2005-07-29 |
Upjohn Co |
Heterocyclic amine-type compounds for treating fibromyalgia and chronic fatigue syndrome
|
|
DE60105023T2
(de)
|
2000-06-28 |
2005-08-18 |
Smithkline Beecham P.L.C., Brentford |
Nassvermahlungsverfahren
|
|
AR030121A1
(es)
|
2000-08-08 |
2003-08-13 |
Sanofi Aventis |
Derivados de benzimidazol, su preparacion y su aplicacion en terapeutica
|
|
FR2816619B1
(fr)
|
2000-11-15 |
2003-01-31 |
Sanofi Synthelabo |
Derives de benzimidazole, leur preparation et leur application en therapeutique
|
|
US6919334B2
(en)
|
2002-09-12 |
2005-07-19 |
Wyeth |
Antidepressant azaheterocyclymethyl derivatives of 4,5-dihydroimidazo[1,4,5-de][1,4]benzoxazine
|
|
AU2003293006A1
(en)
|
2002-11-22 |
2004-06-18 |
Japan Tobacco Inc. |
Fused bicyclic nitrogen-containing heterocycles
|
|
EP1462103A1
(en)
|
2003-03-25 |
2004-09-29 |
Faust Pharmaceuticals |
NO donors, combination products and uses as modulators of neurotransmitter release
|
|
JPWO2005080334A1
(ja)
|
2004-02-23 |
2007-08-02 |
大日本住友製薬株式会社 |
新規ヘテロ環化合物
|
|
US7897607B2
(en)
|
2004-04-07 |
2011-03-01 |
Takeda Pharmaceutical Company Limited |
Cyclic compounds
|
|
US7713954B2
(en)
|
2004-09-30 |
2010-05-11 |
Roche Palo Alto Llc |
Compositions and methods for treating cognitive disorders
|
|
DE102005011058A1
(de)
|
2005-03-10 |
2006-09-14 |
Merck Patent Gmbh |
Substituierte Tetrahydro-pyrrolo-chinolinderivate
|
|
WO2006124874A2
(en)
|
2005-05-12 |
2006-11-23 |
Kalypsys, Inc. |
Inhibitors of b-raf kinase
|
|
EP1887008B1
(en)
|
2005-05-30 |
2021-04-21 |
Mitsubishi Tanabe Pharma Corporation |
Thienotriazolodiazepine compound and a medicinal use thereof
|
|
RU2008101923A
(ru)
|
2005-08-05 |
2009-09-10 |
Астразенека Аб (Se) |
Трициклические бензимидазолы и их применение в качестве модуляторов метаботропного глутаматного рецептора
|
|
WO2009020677A2
(en)
|
2007-04-27 |
2009-02-12 |
University Of Rochester |
Compositions and methods for inhibiting g protein signaling
|
|
US8633186B2
(en)
|
2007-06-08 |
2014-01-21 |
Senomyx Inc. |
Modulation of chemosensory receptors and ligands associated therewith
|
|
US9603848B2
(en)
|
2007-06-08 |
2017-03-28 |
Senomyx, Inc. |
Modulation of chemosensory receptors and ligands associated therewith
|
|
US7928111B2
(en)
|
2007-06-08 |
2011-04-19 |
Senomyx, Inc. |
Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
|
|
WO2009020559A2
(en)
|
2007-08-03 |
2009-02-12 |
The J. David Gladstone Institutes |
Agents that inhibit p-tefb interactions and methods of use thereof
|
|
EP2239264A4
(en)
|
2007-12-28 |
2012-01-11 |
Mitsubishi Tanabe Pharma Corp |
ANTITUMORAL MEDIUM
|
|
DE102008052618A1
(de)
|
2008-10-21 |
2010-04-22 |
Henkel Ag & Co. Kgaa |
Tricyclische Aldehyde und C,H-acide Verbindungen
|
|
EP2415767B1
(en)
|
2009-03-27 |
2014-09-03 |
Takeda Pharmaceutical Company Limited |
Poly (ADP-ribose) Polymerase (PARP) Inhibitors
|
|
TW201105681A
(en)
|
2009-06-10 |
2011-02-16 |
Janssen Pharmaceutica Nv |
Benzimidazole derivatives useful as TRPM8 channel modulators
|
|
TW201103941A
(en)
|
2009-06-10 |
2011-02-01 |
Janssen Pharmaceutica Nv |
Benzimidazole derivatives useful as TRPM8 channel modulators
|
|
WO2011024987A1
(ja)
|
2009-08-31 |
2011-03-03 |
塩野義製薬株式会社 |
芳香族縮合へテロ環誘導体およびそれらを含有する医薬組成物
|
|
GB0919431D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB0919434D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
KR20120097508A
(ko)
|
2009-11-05 |
2012-09-04 |
글락소스미스클라인 엘엘씨 |
벤조디아제핀 브로모도메인 억제제
|
|
GB0919432D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Use
|
|
MY160456A
(en)
|
2009-11-05 |
2017-03-15 |
Glaxosmithkline Llc |
Benzodiazepine bromodomain inhibitor
|
|
GB0919426D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB0919423D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
WO2011054851A1
(en)
|
2009-11-05 |
2011-05-12 |
Glaxosmithkline Llc |
Novel process
|
|
MX2012012353A
(es)
|
2010-04-23 |
2013-02-07 |
Kineta Inc |
Compuestos anti-virales.
|
|
CA2799381A1
(en)
|
2010-05-14 |
2011-11-17 |
Dana-Farber Cancer Institute, Inc. |
Male contraceptive compositions and methods of use
|
|
MX373121B
(es)
|
2010-05-14 |
2020-04-30 |
Dana Farber Cancer Inst Inc |
Composiciones y metodos para el tratamiento de leucemia.
|
|
JP5913292B2
(ja)
|
2010-05-14 |
2016-04-27 |
ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド |
代謝を調節する組成物および方法
|
|
US8981083B2
(en)
|
2010-05-14 |
2015-03-17 |
Dana Farber Cancer Institute, Inc. |
Compositions and methods for treating neoplasia, inflammatory disease and other disorders
|
|
US9085582B2
(en)
|
2010-06-22 |
2015-07-21 |
Glaxosmithkline Llc |
Benzotriazolodiazepine compounds inhibitors of bromodomains
|
|
US9249161B2
(en)
|
2010-12-02 |
2016-02-02 |
Constellation Pharmaceuticals, Inc. |
Bromodomain inhibitors and uses thereof
|
|
AR084070A1
(es)
|
2010-12-02 |
2013-04-17 |
Constellation Pharmaceuticals Inc |
Inhibidores del bromodominio y usos de los mismos
|
|
JP5766820B2
(ja)
|
2011-02-09 |
2015-08-19 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Pi3キナーゼ阻害剤としての複素環化合物
|
|
EP2677865A4
(en)
|
2011-02-23 |
2015-04-22 |
Icahn School Med Mount Sinai |
BROMODOMAIN INHIBITORS AS MODULATORS OF GENE EXPRESSION
|
|
MX340013B
(es)
|
2011-03-21 |
2016-06-22 |
Hoffmann La Roche |
Compuestos de benzoxazepina selectivos para fosfatidilinositol 3-cinasa (pi3k) p110 delta y metodos de uso.
|
|
GB201106799D0
(en)
|
2011-04-21 |
2011-06-01 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB201106743D0
(en)
|
2011-04-21 |
2011-06-01 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB201106750D0
(en)
|
2011-04-21 |
2011-06-01 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB201107325D0
(en)
|
2011-05-04 |
2011-06-15 |
Glaxosmithkline Llc |
Novel compounds
|
|
WO2012151512A2
(en)
|
2011-05-04 |
2012-11-08 |
Constellation Pharmaceuticals, Inc. |
Bromodomain inhibitors and uses thereof
|
|
US9328117B2
(en)
|
2011-06-17 |
2016-05-03 |
Constellation Pharmaceuticals, Inc. |
Bromodomain inhibitors and uses thereof
|
|
US20150197497A1
(en)
|
2011-06-24 |
2015-07-16 |
Dana-Farber Cancer Institute, Inc. |
Selective inhibitors of histone deacetylase isoform 6 and methods thereof
|
|
JP2013010719A
(ja)
|
2011-06-30 |
2013-01-17 |
Dainippon Sumitomo Pharma Co Ltd |
ベンズイミダゾロンおよびオキシインドール誘導体ならびにそれらの医薬用途
|
|
AU2012290261A1
(en)
|
2011-07-29 |
2014-02-20 |
The Children's Hospital Of Philadelphia |
Compositions and methods for the treatment of HIV
|
|
GB201114103D0
(en)
|
2011-08-17 |
2011-09-28 |
Glaxosmithkline Llc |
Novel compounds
|
|
WO2013027168A1
(en)
|
2011-08-22 |
2013-02-28 |
Pfizer Inc. |
Novel heterocyclic compounds as bromodomain inhibitors
|
|
WO2013033270A2
(en)
|
2011-08-29 |
2013-03-07 |
Coferon, Inc. |
Bromodomain ligands capable of dimerizing in an aqueous solution, and methods of using same
|
|
WO2013033269A1
(en)
|
2011-08-29 |
2013-03-07 |
Coferon, Inc. |
Bioorthogonal monomers capable of dimerizing and targeting bromodomains and methods of using same
|
|
KR101560073B1
(ko)
|
2011-08-31 |
2015-10-13 |
오쓰까 세이야꾸 가부시키가이샤 |
퀴놀론 화합물
|
|
DE102011082013A1
(de)
|
2011-09-01 |
2013-03-07 |
Bayer Pharma AG |
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
|
|
ES2632443T3
(es)
|
2011-09-22 |
2017-09-13 |
Viiv Healthcare Uk Limited |
Compuestos de pirrolopiridinona y procedimientos de tratamiento del VIH
|
|
WO2013044511A1
(zh)
|
2011-09-30 |
2013-04-04 |
沈阳蓝桑医药生物技术研发有限公司 |
含有瑞利格内酯的药物组合物及其应用
|
|
EP2771340B1
(en)
|
2011-10-25 |
2016-04-13 |
Sanofi |
6-(4-hydroxy-phenyl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
LT2773354T
(lt)
|
2011-11-01 |
2019-08-12 |
Resverlogix Corp. |
Geriamosios greitai atsipalaiduojančios pakeistų chinozolinų vaisto formos
|
|
WO2013097052A1
(en)
|
2011-12-30 |
2013-07-04 |
Abbott Laboratories |
Bromodomain inhibitors
|
|
EP2830629A4
(en)
|
2012-03-28 |
2016-01-20 |
Icahn School Of Medicine Mount Sinai |
COMPOSITIONS AND METHOD FOR THE REACTIVATION OF LATENT IMMUNE FIZIENZVIRUS
|
|
US20130281396A1
(en)
|
2012-04-19 |
2013-10-24 |
Rvx Therapeutics Inc. |
Treatment of diseases by epigenetic regulation
|
|
US20130281399A1
(en)
|
2012-04-19 |
2013-10-24 |
Rvx Therapeutics Inc. |
Treatment of diseases by epigenetic regulation
|
|
US20130281397A1
(en)
|
2012-04-19 |
2013-10-24 |
Rvx Therapeutics Inc. |
Treatment of diseases by epigenetic regulation
|
|
US20130281398A1
(en)
|
2012-04-19 |
2013-10-24 |
Rvx Therapeutics Inc. |
Treatment of diseases by epigenetic regulation
|
|
CA2870931A1
(en)
|
2012-04-20 |
2013-10-24 |
Abbvie Inc. |
Isoindolone derivatives
|
|
US9624244B2
(en)
|
2012-06-06 |
2017-04-18 |
Constellation Pharmaceuticals, Inc. |
Benzo [B] isoxazoloazepine bromodomain inhibitors and uses thereof
|
|
TWI602820B
(zh)
|
2012-06-06 |
2017-10-21 |
星宿藥物公司 |
溴域抑制劑及其用途
|
|
AU2012382373A1
(en)
|
2012-06-12 |
2014-12-11 |
Abbvie Inc. |
Pyridinone and pyridazinone derivatives
|
|
MX2014015986A
(es)
|
2012-06-25 |
2016-02-11 |
Oncoethix Gmbh |
Metodo para tratar linfoma utilizando compuestos de tienotriazolodiazepina.
|
|
US9610332B2
(en)
|
2012-07-18 |
2017-04-04 |
Massachusetts Institute Of Technology |
Compositions and methods for modulating BRD4 bioactivity
|
|
CN104582708A
(zh)
|
2012-08-16 |
2015-04-29 |
葛兰素史克有限责任公司 |
用于治疗小细胞肺癌的苯并二氮*类
|
|
CA2881996A1
(en)
|
2012-08-16 |
2014-02-20 |
Bayer Pharma Aktiengesellschaft |
2,3-benzodiazepines
|
|
CA2885944A1
(en)
|
2012-09-28 |
2014-05-08 |
Oncoethix Sa |
Pharmaceutical formulation containing thienotriazolodiazepine compounds
|
|
EP2900672B1
(de)
|
2012-09-28 |
2017-02-22 |
Bayer Pharma Aktiengesellschaft |
Bet-proteininhibitorische 5-aryl-triazolo-azepine
|
|
RS59690B1
(sr)
|
2012-11-09 |
2020-01-31 |
Medicines For Malaria Venture Mmv |
Derivativi heteroarila i njihova upotreba
|
|
US9422290B2
(en)
|
2012-11-13 |
2016-08-23 |
Boehringer Ingelheim International Gmbh |
Triazolopyridazine
|
|
WO2014078257A1
(en)
|
2012-11-14 |
2014-05-22 |
Glaxosmithkline Llc |
Thieno[3,2-c]pyridin-4(5h)-ones as bet inhibitors
|
|
US9073878B2
(en)
|
2012-11-21 |
2015-07-07 |
Zenith Epigenetics Corp. |
Cyclic amines as bromodomain inhibitors
|
|
WO2014080291A2
(en)
|
2012-11-21 |
2014-05-30 |
Rvx Therapeutics Inc. |
Biaryl derivatives as bromodomain inhibitors
|
|
EP2935260A1
(de)
|
2012-12-20 |
2015-10-28 |
Bayer Pharma Aktiengesellschaft |
Bet-proteininhibitorische dihydropyridopyrazinone
|
|
JP2016509576A
(ja)
|
2012-12-20 |
2016-03-31 |
バイエル ファーマ アクチエンゲゼルシャフト |
Betタンパク質阻害性ジヒドロキノキザリノン類
|
|
WO2014096965A2
(en)
|
2012-12-21 |
2014-06-26 |
Rvx Therapeutics Inc. |
Novel heterocyclic compounds as bromodomain inhibitors
|
|
WO2014128655A1
(en)
|
2013-02-25 |
2014-08-28 |
Aurigene Discovery Technologies Limited |
Substituted imidazo[4,5-c]quinoline derivatives as bromodomain inhibitors
|
|
JP6404838B2
(ja)
|
2013-02-27 |
2018-10-17 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
ブロモドメイン阻害剤として有用なカルバゾール化合物
|
|
US9492460B2
(en)
|
2013-02-27 |
2016-11-15 |
Bristol-Myers Squibb Company |
Carbazole compounds useful as bromodomain inhibitors
|
|
BR112015022861A8
(pt)
|
2013-03-11 |
2019-11-26 |
Abbvie Inc |
inibidores de bromodomínio
|
|
MX2015012158A
(es)
|
2013-03-11 |
2015-12-01 |
Abbvie Inc |
Inhibidores de bomodominio tetraciclicos fusionados.
|
|
EP2970312B1
(en)
|
2013-03-11 |
2017-11-15 |
The Regents of The University of Michigan |
Bet bromodomain inhibitors and therapeutic methods using the same
|
|
KR20150126696A
(ko)
|
2013-03-12 |
2015-11-12 |
애브비 인코포레이티드 |
디하이드로-피롤로피리디논 브로모도메인 억제제
|
|
US9493411B2
(en)
|
2013-03-12 |
2016-11-15 |
Abbvie Inc. |
Pyrrole-3-carboxamide bromodomain inhibitors
|
|
WO2014139324A1
(en)
|
2013-03-12 |
2014-09-18 |
Abbvie Inc. |
Tetracyclic bromodomain inhibitors
|
|
KR20150128842A
(ko)
|
2013-03-14 |
2015-11-18 |
글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 |
브로모도메인 억제제로서의 퓨로피리딘
|
|
WO2014140076A1
(en)
|
2013-03-14 |
2014-09-18 |
Glaxosmithkline Intellectual Property (No.2) Limited |
2,3-disubstituted 1 -acyl-4-amino-1,2,3,4-tetrahydroquinoline derivatives and their use as bromodomain inhibitors
|
|
CN105407894A
(zh)
|
2013-03-14 |
2016-03-16 |
康威基内有限公司 |
用于抑制含布罗莫结构域的蛋白质的方法和组合物
|
|
US9714946B2
(en)
|
2013-03-14 |
2017-07-25 |
Dana-Farber Cancer Institute, Inc. |
Bromodomain binding reagents and uses thereof
|
|
JP6325078B2
(ja)
|
2013-03-15 |
2018-05-16 |
プレキシコン インコーポレーテッドPlexxikon Inc. |
ヘテロ環式化合物およびその使用
|
|
MX366703B
(es)
|
2013-03-15 |
2019-07-22 |
Incyte Holdings Corp |
Heterociclos tricíclicos como inhibidores de la proteína bet.
|
|
AU2014236606A1
(en)
|
2013-03-15 |
2015-09-24 |
Epigenetix, Inc. |
Oxazolo(5,4-c)quinolin-2-one compounds as bromodomain inhibitors
|
|
US9199988B2
(en)
|
2013-03-27 |
2015-12-01 |
Boehringer Ingelheim International Gmbh |
Dihydroquinazolinone analogues
|
|
EP2978757B1
(en)
|
2013-03-27 |
2017-02-08 |
Boehringer Ingelheim International GmbH |
Indolinone analogues as brd4 inhibitors
|
|
TWI530499B
(zh)
|
2013-03-28 |
2016-04-21 |
吉李德科學股份有限公司 |
作為溴結構域(bromodomain)抑制劑之苯並咪唑酮衍生物類
|
|
EP2996689A1
(en)
|
2013-04-17 |
2016-03-23 |
Albert-Ludwigs-Universität Freiburg |
Compounds for use as bromodomain inhibitors
|
|
CA2901083A1
(en)
|
2013-04-26 |
2014-10-30 |
Beigene, Ltd. |
Substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-ones
|
|
TWI527811B
(zh)
|
2013-05-09 |
2016-04-01 |
吉李德科學股份有限公司 |
作爲溴結構域抑制劑的苯並咪唑衍生物
|
|
US8975417B2
(en)
|
2013-05-27 |
2015-03-10 |
Novartis Ag |
Pyrazolopyrrolidine derivatives and their use in the treatment of disease
|
|
CN105209467B
(zh)
|
2013-05-27 |
2018-06-08 |
诺华股份有限公司 |
咪唑并吡咯烷酮衍生物及其在治疗疾病中的用途
|
|
ES2656471T3
(es)
|
2013-05-28 |
2018-02-27 |
Novartis Ag |
Derivados de pirazolo-pirrolidin-4-ona como inhibidores de BET y su uso en el tratamiento de enfermedades
|
|
ES2650562T3
(es)
|
2013-05-28 |
2018-01-19 |
Novartis Ag |
Derivados de pirazolo-pirrolidin-4-ona y su uso en el tratamiento de enfermedades
|
|
EP3010909A1
(de)
|
2013-06-17 |
2016-04-27 |
Bayer Pharma Aktiengesellschaft |
Substituierte phenyl-2,3-benzodiazepine
|
|
ITMI20130991A1
(it)
|
2013-06-17 |
2014-12-18 |
Industrie De Nora Spa |
Sistema per la misurazione di correnti presenti sugli elettrodi in celle elettrolitiche interconnesse.
|
|
SG11201510409QA
(en)
|
2013-06-21 |
2016-01-28 |
Zenith Epigenetics Corp |
Novel bicyclic bromodomain inhibitors
|
|
WO2015004533A2
(en)
|
2013-06-21 |
2015-01-15 |
Zenith Epigenetics Corp. |
Novel substituted bicyclic compounds as bromodomain inhibitors
|
|
WO2014206150A1
(en)
|
2013-06-28 |
2014-12-31 |
Abbvie Inc. |
Bromodomain inhibitors
|
|
AR096758A1
(es)
*
|
2013-06-28 |
2016-02-03 |
Abbvie Inc |
Inhibidores cristalinos de bromodominios
|
|
WO2015006193A1
(en)
|
2013-07-08 |
2015-01-15 |
Incyte Corporation |
Tricyclic heterocycles as bet protein inhibitors
|
|
PL3022191T3
(pl)
|
2013-07-16 |
2017-08-31 |
Basf Se |
Chwastobójcze azyny
|
|
BR112016001457A2
(pt)
|
2013-07-25 |
2017-08-29 |
Dana Farber Cancer Inst Inc |
Inibidores de fatores de transcrição e usos dos mesmos
|
|
KR101672096B1
(ko)
|
2013-09-30 |
2016-11-02 |
주식회사 엘지화학 |
헤테로환 화합물 및 이를 포함하는 유기 발광 소자
|
|
AU2014337064B2
(en)
|
2013-10-18 |
2019-03-14 |
Celgene Quanticel Research, Inc. |
Bromodomain inhibitors
|
|
US9315501B2
(en)
|
2013-11-26 |
2016-04-19 |
Incyte Corporation |
Bicyclic heterocycles as BET protein inhibitors
|
|
WO2015081203A1
(en)
|
2013-11-26 |
2015-06-04 |
Incyte Corporation |
Bicyclic heterocycles as bet protein inhibitors
|
|
WO2015081246A1
(en)
|
2013-11-26 |
2015-06-04 |
Incyte Corporation |
Bicyclic heterocycles as bet protein inhibitors
|
|
MX2016007346A
(es)
|
2013-12-09 |
2016-09-13 |
Abbvie Inc |
Derivados de dihidropiridinona y dihidropiridazinona utiles como inhibidores de bromodominio.
|
|
US9309246B2
(en)
|
2013-12-19 |
2016-04-12 |
Incyte Corporation |
Tricyclic heterocycles as BET protein inhibitors
|
|
EP3083559B1
(en)
*
|
2013-12-20 |
2021-03-10 |
Merck Sharp & Dohme Corp. |
Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
|
|
LT3092227T
(lt)
|
2014-01-09 |
2018-08-10 |
Orion Corporation |
Bicikliniai heterocikliniai dariniai kaip bromodomeno inhibitoriai
|
|
US9580430B2
(en)
|
2014-02-28 |
2017-02-28 |
The Regents Of The University Of Michigan |
9H-pyrimido[4,5-B]indoles and related analogs as BET bromodomain inhibitors
|
|
MX373274B
(es)
|
2014-04-23 |
2020-04-16 |
Takeda Pharmaceuticals Co |
Derivados de isoindolin-1-ona con actividad de modulador alostérico positivo del receptor colinérgico muscarínico m1 para el tratamiento de la enfermedad de alzheimer.
|
|
UA119870C2
(uk)
|
2014-04-23 |
2019-08-27 |
Інсайт Корпорейшн |
1H-ПІРОЛО[2,3-c]ПІРИДИН-7(6H)-ОНИ ТА ПІРАЗОЛО[3,4-c]ПІРИДИН-7(6H)-ОНИ ЯК ІНГІБІТОРИ БІЛКІВ BET
|
|
CR20160545A
(es)
|
2014-04-23 |
2017-03-31 |
Basf Se |
Compuestos de diaminotriazina como herbicidas
|
|
JP2017514907A
(ja)
|
2014-05-02 |
2017-06-08 |
オンコエシックス ゲーエムベーハー |
チエノトリアゾロジアゼピン化合物を用いる耐性非ホジキンリンパ腫、髄芽腫及び/又はalk+非小細胞肺癌の治療方法
|
|
KR20160145833A
(ko)
|
2014-05-02 |
2016-12-20 |
온코에틱스 게엠베하 |
티에노트리아졸로디아제핀 화합물을 사용한 급성 골수성 백혈병 및/또는 급성 림프아구성 백혈병의 치료 방법
|
|
MX2016014574A
(es)
|
2014-05-08 |
2017-02-23 |
Oncoethix Gmbh |
El uso de compuestos de tienotriazolodiazepina para el tratamiento de cancer de mama triple-negativo.
|
|
WO2015169953A1
(en)
|
2014-05-08 |
2015-11-12 |
Oncoethix Gmbh |
Method of treating glioma using thienotriazolodiazepine compounds
|
|
US10065951B2
(en)
|
2014-05-30 |
2018-09-04 |
Icahn School Of Medicine At Mount Sinai |
Small molecule transcription modulators of bromodomains
|
|
CN106687463B
(zh)
|
2014-06-20 |
2019-04-09 |
星座制药公司 |
一种乙酰胺类化合物的晶型
|
|
US9861077B2
(en)
|
2014-07-11 |
2018-01-09 |
Jaan Aked-Hurditch |
Leash accessory
|
|
ES2855225T3
(es)
|
2014-09-15 |
2021-09-23 |
Incyte Corp |
Heterociclos tricíclicos para su uso como inhibidores de proteínas BET
|
|
PT3461821T
(pt)
|
2014-10-24 |
2020-08-05 |
Bristol Myers Squibb Co |
Compostos de indol carboxamida úteis como inibidores de quinase
|
|
MA40943A
(fr)
|
2014-11-10 |
2017-09-19 |
Constellation Pharmaceuticals Inc |
Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines
|
|
CA2974153A1
(en)
|
2015-02-03 |
2016-08-11 |
Trillium Therapeutics Inc. |
Fluorinated imidazo[4,5-c]quinoline derivatives as inhibitors of bromodomain containing proteins
|
|
WO2016186453A1
(en)
|
2015-05-20 |
2016-11-24 |
Kainos Medicine, Inc. |
Quinoline derivatives as bromodomain inhibitors
|
|
SG11201709634QA
(en)
|
2015-05-29 |
2017-12-28 |
Shionogi & Co |
Nitrogen-containing tricyclic derivative having hiv replication inhibitory activity
|
|
CN105039258B
(zh)
|
2015-07-03 |
2018-04-17 |
北京大学 |
将非神经元细胞重编程为神经元样细胞的方法和组合物
|
|
TW201722966A
(zh)
|
2015-10-29 |
2017-07-01 |
英塞特公司 |
Bet蛋白質抑制劑之非晶固體形式
|
|
CN105254635A
(zh)
|
2015-10-30 |
2016-01-20 |
中国药科大学 |
一类咪唑并吡嗪类化合物及其药物组合物和用途
|
|
US20170127985A1
(en)
|
2015-11-11 |
2017-05-11 |
Medtronic Minimed, Inc. |
Sensor set
|
|
CN108602821B
(zh)
|
2015-12-14 |
2021-06-29 |
恒元生物医药科技(苏州)有限公司 |
1h-咪唑并[4,5-b]吡啶基bet溴结构域抑制剂
|
|
WO2017127930A1
(en)
|
2016-01-28 |
2017-08-03 |
Neomed Institute |
Substituted [1,2,4]triazolo[4,3-a]pyridines, their preparation and their use as pharmaceuticals
|
|
EP3412669A4
(en)
|
2016-02-05 |
2019-09-04 |
Chia Tai Tianqing Pharmaceutical Group Co.,Ltd |
TRICYCLIC COMPOUND FOR PROTEIN INHIBITOR CONTAINING BROMODOMAINE AND PREPARATION, PHARMACEUTICAL COMPOSITION AND USE THEREOF
|
|
AU2017281286B2
(en)
*
|
2016-06-20 |
2021-05-20 |
Incyte Corporation |
Crystalline solid forms of a bet inhibitor
|
|
CN108069958A
(zh)
|
2016-11-10 |
2018-05-25 |
凯惠科技发展(上海)有限公司 |
一种含氮杂环类化合物、其制备方法、药物组合物及应用
|