|
JPS59170313A
(ja)
|
1983-03-14 |
1984-09-26 |
Kurimoto Iron Works Ltd |
スクリ−ンゲ−ト
|
|
JPS6085739U
(ja)
|
1983-11-18 |
1985-06-13 |
クラリオン株式会社 |
テ−プレコ−ダにおけるピンチロ−ラ装置
|
|
JPS6243003U
(enExample)
|
1985-09-05 |
1987-03-14 |
|
|
|
JPH0314566A
(ja)
|
1989-06-09 |
1991-01-23 |
Sankyo Co Ltd |
ベンズイミダゾール誘導体
|
|
US5244912A
(en)
|
1991-03-28 |
1993-09-14 |
Eli Lilly And Company |
6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
|
|
FR2710915B1
(fr)
|
1993-10-04 |
1995-11-24 |
Synthelabo |
Dérivés de pipéridine, leur préparation et leur utilisation en thérapeutique.
|
|
GB9410469D0
(en)
|
1994-05-25 |
1994-07-13 |
Erba Farmitalia |
Imidazolylalkyl derivatives of imidazo (5,1-c) (1,4) benzoxazin-1-one and process for their preparation
|
|
FR2731708B1
(fr)
|
1995-03-13 |
1997-04-30 |
Synthelabo |
Derives de piperidine, leur procede de preparation et leur application en therapeutique
|
|
FR2747678B1
(fr)
|
1996-04-22 |
1998-05-22 |
Synthelabo |
Composes derives d'imidazobenzoxazine, leurs procedes de preparation et leurs utilisations en therapeutique
|
|
US6287693B1
(en)
|
1998-02-25 |
2001-09-11 |
John Claude Savoir |
Stable shaped particles of crystalline organic compounds
|
|
CN1450898A
(zh)
|
2000-04-21 |
2003-10-22 |
法玛西雅厄普约翰美国公司 |
用于治疗纤维肌痛和慢性疲劳综合症的化合物
|
|
KR100786927B1
(ko)
|
2000-06-28 |
2007-12-17 |
스미스클라인비이참피이엘시이 |
습식 분쇄방법
|
|
FR2816619B1
(fr)
|
2000-11-15 |
2003-01-31 |
Sanofi Synthelabo |
Derives de benzimidazole, leur preparation et leur application en therapeutique
|
|
EP1309594B1
(fr)
|
2000-08-08 |
2004-12-15 |
Sanofi-Aventis |
Derives de benzimidazole, leur preparation et leur application en therapeutique
|
|
US6919334B2
(en)
|
2002-09-12 |
2005-07-19 |
Wyeth |
Antidepressant azaheterocyclymethyl derivatives of 4,5-dihydroimidazo[1,4,5-de][1,4]benzoxazine
|
|
RU2342388C2
(ru)
|
2002-11-22 |
2008-12-27 |
Джапан Тобакко Инк. |
Конденсированные бициклические азотсодержащие гетероциклы, обладающие dgat ингибирующим действием
|
|
EP1462103A1
(en)
|
2003-03-25 |
2004-09-29 |
Faust Pharmaceuticals |
NO donors, combination products and uses as modulators of neurotransmitter release
|
|
CN1922141A
(zh)
|
2004-02-23 |
2007-02-28 |
大日本住友制药株式会社 |
新的杂环化合物
|
|
EP1732541A4
(en)
|
2004-04-07 |
2008-03-05 |
Takeda Pharmaceutical |
CYCLIC COMPOUNDS
|
|
US7713954B2
(en)
|
2004-09-30 |
2010-05-11 |
Roche Palo Alto Llc |
Compositions and methods for treating cognitive disorders
|
|
DE102005011058A1
(de)
|
2005-03-10 |
2006-09-14 |
Merck Patent Gmbh |
Substituierte Tetrahydro-pyrrolo-chinolinderivate
|
|
WO2006124874A2
(en)
|
2005-05-12 |
2006-11-23 |
Kalypsys, Inc. |
Inhibitors of b-raf kinase
|
|
WO2006129623A1
(ja)
|
2005-05-30 |
2006-12-07 |
Mitsubishi Tanabe Pharma Corporation |
チエノトリアゾロジアゼピン化合物及びその医薬としての用途
|
|
US20070032469A1
(en)
|
2005-08-05 |
2007-02-08 |
Astrazeneca Ab |
Tricyclic benzimidazoles and their use as metabotropic glutamate receptor modulators
|
|
EP2147310A4
(en)
|
2007-04-27 |
2010-09-08 |
Univ Rochester |
COMPOSITIONS AND METHODS OF INHIBITING G-PROTEIN SIGNALING
|
|
US9603848B2
(en)
|
2007-06-08 |
2017-03-28 |
Senomyx, Inc. |
Modulation of chemosensory receptors and ligands associated therewith
|
|
US8633186B2
(en)
|
2007-06-08 |
2014-01-21 |
Senomyx Inc. |
Modulation of chemosensory receptors and ligands associated therewith
|
|
US7928111B2
(en)
|
2007-06-08 |
2011-04-19 |
Senomyx, Inc. |
Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
|
|
WO2009020559A2
(en)
|
2007-08-03 |
2009-02-12 |
The J. David Gladstone Institutes |
Agents that inhibit p-tefb interactions and methods of use thereof
|
|
KR101600634B1
(ko)
|
2007-12-28 |
2016-03-07 |
미쓰비시 타나베 파마 코퍼레이션 |
항암제
|
|
DE102008052618A1
(de)
|
2008-10-21 |
2010-04-22 |
Henkel Ag & Co. Kgaa |
Tricyclische Aldehyde und C,H-acide Verbindungen
|
|
WO2010111626A2
(en)
|
2009-03-27 |
2010-09-30 |
Takeda Pharmaceutical Company Limited |
Poly (adp-ribose) polymerase (parp) inhibitors
|
|
TW201105681A
(en)
|
2009-06-10 |
2011-02-16 |
Janssen Pharmaceutica Nv |
Benzimidazole derivatives useful as TRPM8 channel modulators
|
|
TW201103941A
(en)
|
2009-06-10 |
2011-02-01 |
Janssen Pharmaceutica Nv |
Benzimidazole derivatives useful as TRPM8 channel modulators
|
|
WO2011024987A1
(ja)
|
2009-08-31 |
2011-03-03 |
塩野義製薬株式会社 |
芳香族縮合へテロ環誘導体およびそれらを含有する医薬組成物
|
|
GB0919431D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB0919434D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB0919423D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
EP3050885B1
(en)
|
2009-11-05 |
2017-10-18 |
GlaxoSmithKline LLC |
Benzodiazepine bromodomain inhibitor
|
|
WO2011054851A1
(en)
|
2009-11-05 |
2011-05-12 |
Glaxosmithkline Llc |
Novel process
|
|
AU2010314395B2
(en)
|
2009-11-05 |
2015-04-09 |
Glaxosmithkline Llc |
Benzodiazepine bromodomain inhibitor
|
|
GB0919426D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB0919432D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Use
|
|
KR20130069640A
(ko)
|
2010-04-23 |
2013-06-26 |
키네타, 인크. |
항-바이러스 화합물
|
|
PL2902030T3
(pl)
|
2010-05-14 |
2017-07-31 |
Dana-Farber Cancer Institute, Inc. |
Związki tienotriazolodiazepinowe do leczenia nowotworu
|
|
EP2571875A4
(en)
|
2010-05-14 |
2013-10-30 |
Dana Farber Cancer Inst Inc |
CONTRACEPTIVE COMPOSITIONS FOR MEN AND METHODS OF USE THEREOF
|
|
MX354217B
(es)
|
2010-05-14 |
2018-02-19 |
Dana Farber Cancer Inst Inc |
Composiciones y metodos para el tratamiento de leucemia.
|
|
CN103119160B
(zh)
|
2010-05-14 |
2016-06-01 |
达那-法伯癌症研究所 |
用于调节代谢的组合物和方法
|
|
JP5844358B2
(ja)
|
2010-06-22 |
2016-01-13 |
グラクソスミスクライン エルエルシー |
ベンゾトリアゾロジアゼピン化合物を含むブロモドメイン阻害剤
|
|
WO2012075456A1
(en)
|
2010-12-02 |
2012-06-07 |
Constellation Pharmaceuticals |
Bromodomain inhibitors and uses thereof
|
|
AR084070A1
(es)
|
2010-12-02 |
2013-04-17 |
Constellation Pharmaceuticals Inc |
Inhibidores del bromodominio y usos de los mismos
|
|
RU2013138835A
(ru)
|
2011-02-09 |
2015-03-20 |
Ф. Хоффманн-Ля Рош Аг |
Гетероциклические соединения в качестве ингибиторов pi3 киназы
|
|
AU2012220620A1
(en)
|
2011-02-23 |
2013-10-03 |
Icahn School Of Medicine At Mount Sinai |
Inhibitors of bromodomains as modulators of gene expression
|
|
US9090628B2
(en)
|
2011-03-21 |
2015-07-28 |
Genentech, Inc. |
Benzoxazepin compounds selective for PI3K P110 delta and methods of use
|
|
GB201106799D0
(en)
|
2011-04-21 |
2011-06-01 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB201106750D0
(en)
|
2011-04-21 |
2011-06-01 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB201106743D0
(en)
|
2011-04-21 |
2011-06-01 |
Glaxosmithkline Llc |
Novel compounds
|
|
GB201107325D0
(en)
|
2011-05-04 |
2011-06-15 |
Glaxosmithkline Llc |
Novel compounds
|
|
US9422292B2
(en)
|
2011-05-04 |
2016-08-23 |
Constellation Pharmaceuticals, Inc. |
Bromodomain inhibitors and uses thereof
|
|
WO2012174487A2
(en)
|
2011-06-17 |
2012-12-20 |
Constellation Pharmaceuticals, Inc. |
Bromodomain inhibitors and uses thereof
|
|
US20150197497A1
(en)
|
2011-06-24 |
2015-07-16 |
Dana-Farber Cancer Institute, Inc. |
Selective inhibitors of histone deacetylase isoform 6 and methods thereof
|
|
JP2013010719A
(ja)
|
2011-06-30 |
2013-01-17 |
Dainippon Sumitomo Pharma Co Ltd |
ベンズイミダゾロンおよびオキシインドール誘導体ならびにそれらの医薬用途
|
|
CA2843643A1
(en)
|
2011-07-29 |
2013-02-07 |
The Children's Hospital Of Philadelphia |
Compositions and methods for the treatment of hiv
|
|
GB201114103D0
(en)
|
2011-08-17 |
2011-09-28 |
Glaxosmithkline Llc |
Novel compounds
|
|
WO2013027168A1
(en)
|
2011-08-22 |
2013-02-28 |
Pfizer Inc. |
Novel heterocyclic compounds as bromodomain inhibitors
|
|
WO2013033269A1
(en)
|
2011-08-29 |
2013-03-07 |
Coferon, Inc. |
Bioorthogonal monomers capable of dimerizing and targeting bromodomains and methods of using same
|
|
WO2013033268A2
(en)
|
2011-08-29 |
2013-03-07 |
Coferon, Inc. |
Bivalent bromodomain ligands, and methods of using same
|
|
SG2014004162A
(en)
|
2011-08-31 |
2014-03-28 |
Otsuka Pharma Co Ltd |
Quinolone compound
|
|
DE102011082013A1
(de)
|
2011-09-01 |
2013-03-07 |
Bayer Pharma AG |
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
|
|
EP2757887B1
(en)
|
2011-09-22 |
2017-04-26 |
VIIV Healthcare UK Limited |
Pyrrolopyridinone compounds and methods for treating hiv
|
|
WO2013044511A1
(zh)
|
2011-09-30 |
2013-04-04 |
沈阳蓝桑医药生物技术研发有限公司 |
含有瑞利格内酯的药物组合物及其应用
|
|
EP2771340B1
(en)
|
2011-10-25 |
2016-04-13 |
Sanofi |
6-(4-hydroxy-phenyl)-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
|
|
CA2851996C
(en)
|
2011-11-01 |
2020-01-07 |
Resverlogix Corp. |
Pharmaceutical compositions for substituted quinazolinones
|
|
WO2013097052A1
(en)
|
2011-12-30 |
2013-07-04 |
Abbott Laboratories |
Bromodomain inhibitors
|
|
WO2013148197A1
(en)
|
2012-03-28 |
2013-10-03 |
The J. David Gladstone Institutes |
Compositions and methods for reactivating latent immunodeficiency virus
|
|
US20130281396A1
(en)
|
2012-04-19 |
2013-10-24 |
Rvx Therapeutics Inc. |
Treatment of diseases by epigenetic regulation
|
|
US20130281397A1
(en)
|
2012-04-19 |
2013-10-24 |
Rvx Therapeutics Inc. |
Treatment of diseases by epigenetic regulation
|
|
US20130281399A1
(en)
|
2012-04-19 |
2013-10-24 |
Rvx Therapeutics Inc. |
Treatment of diseases by epigenetic regulation
|
|
US20130281398A1
(en)
|
2012-04-19 |
2013-10-24 |
Rvx Therapeutics Inc. |
Treatment of diseases by epigenetic regulation
|
|
CA2870931A1
(en)
|
2012-04-20 |
2013-10-24 |
Abbvie Inc. |
Isoindolone derivatives
|
|
US9624244B2
(en)
|
2012-06-06 |
2017-04-18 |
Constellation Pharmaceuticals, Inc. |
Benzo [B] isoxazoloazepine bromodomain inhibitors and uses thereof
|
|
TWI602820B
(zh)
|
2012-06-06 |
2017-10-21 |
星宿藥物公司 |
溴域抑制劑及其用途
|
|
AU2012382373A1
(en)
|
2012-06-12 |
2014-12-11 |
Abbvie Inc. |
Pyridinone and pyridazinone derivatives
|
|
AU2013283378B2
(en)
|
2012-06-25 |
2017-07-13 |
Oncoethix Gmbh |
Method of treating lymphoma using thienotriazolodiazepine compounds
|
|
US9610332B2
(en)
|
2012-07-18 |
2017-04-04 |
Massachusetts Institute Of Technology |
Compositions and methods for modulating BRD4 bioactivity
|
|
JP2015524847A
(ja)
|
2012-08-16 |
2015-08-27 |
グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーGlaxoSmithKline LLC |
小細胞肺がんを治療するためのベンゾジアゼピン
|
|
EP2885286B1
(de)
|
2012-08-16 |
2017-03-22 |
Bayer Pharma Aktiengesellschaft |
2,3-benzodiazepine
|
|
EP2900672B1
(de)
|
2012-09-28 |
2017-02-22 |
Bayer Pharma Aktiengesellschaft |
Bet-proteininhibitorische 5-aryl-triazolo-azepine
|
|
JP2015531365A
(ja)
|
2012-09-28 |
2015-11-02 |
オンコエシックス エスエー |
チエノトリアゾロジアゼピン化合物を含む医薬製剤
|
|
AP2015008433A0
(en)
|
2012-11-09 |
2015-05-31 |
Jacobus Pahrmaceutical Company Inc |
Heteroaryl derivatives and uses thereof
|
|
US9422290B2
(en)
|
2012-11-13 |
2016-08-23 |
Boehringer Ingelheim International Gmbh |
Triazolopyridazine
|
|
ES2625945T3
(es)
|
2012-11-14 |
2017-07-21 |
Glaxosmithkline Llc |
Tieno[3,2-c]piridin-4(5H)-onas como inhibidores de bet
|
|
US9073878B2
(en)
|
2012-11-21 |
2015-07-07 |
Zenith Epigenetics Corp. |
Cyclic amines as bromodomain inhibitors
|
|
US9765039B2
(en)
|
2012-11-21 |
2017-09-19 |
Zenith Epigenetics Ltd. |
Biaryl derivatives as bromodomain inhibitors
|
|
CN105229002A
(zh)
|
2012-12-20 |
2016-01-06 |
拜耳医药股份有限公司 |
抑制bet蛋白的二氢吡啶并吡嗪酮
|
|
CA2895426A1
(en)
|
2012-12-20 |
2014-06-26 |
Bayer Pharma Aktiengesellschaft |
Bet-protein-inhibiting dihydroquinoxalinones
|
|
JP2016507496A
(ja)
|
2012-12-21 |
2016-03-10 |
ゼニス・エピジェネティクス・コーポレイションZenith Epigenetics Corp. |
ブロモドメイン阻害剤としての新規複素環式化合物
|
|
WO2014128655A1
(en)
|
2013-02-25 |
2014-08-28 |
Aurigene Discovery Technologies Limited |
Substituted imidazo[4,5-c]quinoline derivatives as bromodomain inhibitors
|
|
US9492460B2
(en)
|
2013-02-27 |
2016-11-15 |
Bristol-Myers Squibb Company |
Carbazole compounds useful as bromodomain inhibitors
|
|
EP2961747B1
(en)
|
2013-02-27 |
2017-11-15 |
Bristol-Myers Squibb Company |
Carbazole compounds useful as bromodomain inhibitors
|
|
EP2970312B1
(en)
|
2013-03-11 |
2017-11-15 |
The Regents of The University of Michigan |
Bet bromodomain inhibitors and therapeutic methods using the same
|
|
US9050346B2
(en)
|
2013-03-11 |
2015-06-09 |
Abbvie Inc. |
Bromodomain inhibitors
|
|
MX2015012158A
(es)
|
2013-03-11 |
2015-12-01 |
Abbvie Inc |
Inhibidores de bomodominio tetraciclicos fusionados.
|
|
BR112015022643A2
(pt)
|
2013-03-12 |
2017-07-18 |
Abbvie Inc |
inibidores diidro-pirrolpiridinona
|
|
UY35395A
(es)
|
2013-03-12 |
2014-10-31 |
Abbvie Inc |
Inhibidores de bromodominios tetracíclicos
|
|
BR112015022551A2
(pt)
|
2013-03-12 |
2017-07-18 |
Abbvie Inc |
inibidores de amido pirrol
|
|
US9670221B2
(en)
|
2013-03-14 |
2017-06-06 |
Glaxosmithkline Intellectual Property (No. 2) Limited |
Furopyridines as bromodomain inhibitors
|
|
HUE043568T2
(hu)
|
2013-03-14 |
2019-08-28 |
Glaxosmithkline Ip No 2 Ltd |
2,3-diszubsztituált 1-acil-4-amino-1,2,3,4-tetrahidrokinolin származékok és bromodomén inhibitorokkénti felhasználásuk
|
|
EA201591746A1
(ru)
|
2013-03-14 |
2016-08-31 |
КОНВЕРДЖЕН ЭлЭлСи |
Способы и композиции для ингибирования бромодомен-содержащих белков
|
|
WO2014159392A1
(en)
|
2013-03-14 |
2014-10-02 |
Dana-Farber Cancer Institute, Inc. |
Bromodomain binding reagents and uses thereof
|
|
DK2970265T3
(en)
|
2013-03-15 |
2018-10-01 |
Plexxikon Inc |
HETEROCYCLIC COMPOUNDS AND APPLICATIONS THEREOF
|
|
CA2904364A1
(en)
|
2013-03-15 |
2014-09-25 |
Epigenetix, Inc. |
Oxazolo[5,4-c]quinolin-2-one compounds as bromodomain inhibitors
|
|
SG11201506924YA
(en)
|
2013-03-15 |
2015-09-29 |
Incyte Corp |
Tricyclic heterocycles as bet protein inhibitors
|
|
JP6453845B2
(ja)
|
2013-03-27 |
2019-01-16 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Brd4阻害薬としてのジヒドロキナゾリノン類似体
|
|
JP6370368B2
(ja)
|
2013-03-27 |
2018-08-08 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Brd4阻害剤としてのインドリノン類似体
|
|
TWI530499B
(zh)
|
2013-03-28 |
2016-04-21 |
吉李德科學股份有限公司 |
作為溴結構域(bromodomain)抑制劑之苯並咪唑酮衍生物類
|
|
EP2996689A1
(en)
|
2013-04-17 |
2016-03-23 |
Albert-Ludwigs-Universität Freiburg |
Compounds for use as bromodomain inhibitors
|
|
US9393232B2
(en)
|
2013-04-26 |
2016-07-19 |
Beigene, Ltd. |
Substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-ones
|
|
TWI527811B
(zh)
|
2013-05-09 |
2016-04-01 |
吉李德科學股份有限公司 |
作爲溴結構域抑制劑的苯並咪唑衍生物
|
|
US8975417B2
(en)
|
2013-05-27 |
2015-03-10 |
Novartis Ag |
Pyrazolopyrrolidine derivatives and their use in the treatment of disease
|
|
EP3412675A1
(en)
|
2013-05-27 |
2018-12-12 |
Novartis AG |
Imidazopyrrolidinone derivatives and their use in the treatment of disease
|
|
MX2015016421A
(es)
|
2013-05-28 |
2016-03-03 |
Novartis Ag |
Derivados de pirazolo-pirrolidin-4-ona como inhibidores de bet y su uso en el tratamiento de enfermedades.
|
|
AU2014272700B2
(en)
|
2013-05-28 |
2016-12-01 |
Novartis Ag |
Pyrazolo-pyrrolidin-4-one derivatives and their use in the treatment of disease
|
|
ITMI20130991A1
(it)
|
2013-06-17 |
2014-12-18 |
Industrie De Nora Spa |
Sistema per la misurazione di correnti presenti sugli elettrodi in celle elettrolitiche interconnesse.
|
|
WO2014202578A1
(de)
|
2013-06-17 |
2014-12-24 |
Bayer Pharma Aktiengesellschaft |
Substituierte phenyl-2,3-benzodiazepine
|
|
SI3010503T1
(sl)
|
2013-06-21 |
2020-07-31 |
Zenith Epigenetics Ltd. |
Novi biciklični inhibitorji bromodomene
|
|
JP6461118B2
(ja)
|
2013-06-21 |
2019-01-30 |
ゼニス・エピジェネティクス・リミテッドZenith Epigenetics Ltd. |
ブロモドメイン阻害剤としての新規の置換された二環式化合物
|
|
WO2014206150A1
(en)
|
2013-06-28 |
2014-12-31 |
Abbvie Inc. |
Bromodomain inhibitors
|
|
AR096758A1
(es)
*
|
2013-06-28 |
2016-02-03 |
Abbvie Inc |
Inhibidores cristalinos de bromodominios
|
|
EP3019502B1
(en)
|
2013-07-08 |
2017-05-17 |
Incyte Holdings Corporation |
Tricyclic heterocycles as bet protein inhibitors
|
|
BR112015033042B1
(pt)
|
2013-07-16 |
2020-10-13 |
Basf Se |
composto de azina, processos para a preparação de composto de azina, composição agroquímica, processo para a preparação de composições agroquímicas, método para controlar vegetação e uso do composto de azina
|
|
US9975896B2
(en)
|
2013-07-25 |
2018-05-22 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of transcription factors and uses thereof
|
|
KR101672096B1
(ko)
|
2013-09-30 |
2016-11-02 |
주식회사 엘지화학 |
헤테로환 화합물 및 이를 포함하는 유기 발광 소자
|
|
SG10201804471PA
(en)
|
2013-10-18 |
2018-07-30 |
Celgene Quanticel Research Inc |
Bromodomain inhibitors
|
|
US9399640B2
(en)
|
2013-11-26 |
2016-07-26 |
Incyte Corporation |
Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors
|
|
WO2015081246A1
(en)
|
2013-11-26 |
2015-06-04 |
Incyte Corporation |
Bicyclic heterocycles as bet protein inhibitors
|
|
WO2015081189A1
(en)
|
2013-11-26 |
2015-06-04 |
Incyte Corporation |
Bicyclic heterocycles as bet protein inhibitors
|
|
EP3089970B1
(en)
|
2013-12-09 |
2018-10-17 |
AbbVie Inc. |
Dihydropyridinone and dihydropyridazinone derivatives useful as bromodomain inhibitors
|
|
WO2015095492A1
(en)
|
2013-12-19 |
2015-06-25 |
Incyte Corporation |
Tricyclic heterocycles as bet protein inhibitors
|
|
US9822107B2
(en)
*
|
2013-12-20 |
2017-11-21 |
Merck Sharp & Dohme Corp. |
Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors
|
|
HUE041546T2
(hu)
|
2014-01-09 |
2019-05-28 |
Orion Corp |
Biciklusos heterociklusos származékvegyületek mint bromo doméninhibitorok
|
|
WO2015131005A1
(en)
|
2014-02-28 |
2015-09-03 |
The Regents Of The University Of Michigan |
9h-pyrimido[4,5-b]indoles and related analogs as bet bromodomain inhibitors
|
|
DK3134386T3
(da)
|
2014-04-23 |
2020-08-17 |
Takeda Pharmaceuticals Co |
Isoindolin-1-on-derivater med kolinerg muscarin-m1-receptor-positiv allosterisk modulatoraktivitet til behandling af alzheimers sygdom
|
|
JP6538077B2
(ja)
|
2014-04-23 |
2019-07-03 |
ビーエーエスエフ ソシエタス・ヨーロピアBasf Se |
除草剤としてのジアミノトリアジン化合物
|
|
PL3134403T3
(pl)
|
2014-04-23 |
2020-07-13 |
Incyte Corporation |
1H-pirolo[2,3-c]pirydyn-7(6H)-ony i pirazolo[3,4-c]pirydyn-7(6H)-ony jako inhibitory białek BET
|
|
EP3137085A4
(en)
|
2014-05-02 |
2017-12-27 |
Oncoethix GmbH |
Method of treating acute myeloid leukemia and/or acute lymphoblastic leukemia using thienotriazolodiazepine compounds
|
|
US20170095484A1
(en)
|
2014-05-02 |
2017-04-06 |
Oncoethix Gmbh |
Method of treating resistant non-hodgkin lymphoma, medulloblastoma, and/or alk+non-small cell lung cancer using thienotriazolodiazepine compounds
|
|
AU2015257658A1
(en)
|
2014-05-08 |
2016-11-10 |
Oncoethix Gmbh |
Method of treating triple-negative breast cancer using thienotriazolodiazepine compounds
|
|
WO2015169953A1
(en)
|
2014-05-08 |
2015-11-12 |
Oncoethix Gmbh |
Method of treating glioma using thienotriazolodiazepine compounds
|
|
EP3148543B1
(en)
|
2014-05-30 |
2020-04-08 |
Icahn School of Medicine at Mount Sinai |
Small molecule transcription modulators of bromodomains
|
|
PL3157928T3
(pl)
|
2014-06-20 |
2019-07-31 |
Constellation Pharmaceuticals, Inc. |
Krystaliczne postacie 2-((4S)-6-(4-chlorofenylo)-1-metylo-4H-benzo[ c]izoksazolo-[4,5-e]azepin-4-ylo)acetamidu
|
|
US9861077B2
(en)
|
2014-07-11 |
2018-01-09 |
Jaan Aked-Hurditch |
Leash accessory
|
|
JP6599979B2
(ja)
|
2014-09-15 |
2019-10-30 |
インサイト・コーポレイション |
Betタンパク質阻害剤として用いるための三環式複素環化合物
|
|
PE20190710A1
(es)
|
2014-10-24 |
2019-05-17 |
Bristol Myers Squibb Co |
Compuestos de indol carboxamida utiles como inhibidores de cinasas
|
|
MA40943A
(fr)
*
|
2014-11-10 |
2017-09-19 |
Constellation Pharmaceuticals Inc |
Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines
|
|
US10259809B2
(en)
|
2015-02-03 |
2019-04-16 |
Trillium Therapeutics Inc. |
Fluorinated imidazo[4,5-C]quinoline derivatives as inhibitors of bromodomain containing proteins
|
|
WO2016186453A1
(en)
|
2015-05-20 |
2016-11-24 |
Kainos Medicine, Inc. |
Quinoline derivatives as bromodomain inhibitors
|
|
TWI700284B
(zh)
|
2015-05-29 |
2020-08-01 |
日商塩野義製藥股份有限公司 |
具有hiv複製抑制作用之含氮3環性衍生物
|
|
CN105039258B
(zh)
|
2015-07-03 |
2018-04-17 |
北京大学 |
将非神经元细胞重编程为神经元样细胞的方法和组合物
|
|
WO2017075377A1
(en)
|
2015-10-29 |
2017-05-04 |
Incyte Corporation |
Amorphous solid form of a bet protein inhibitor
|
|
CN105254635A
(zh)
|
2015-10-30 |
2016-01-20 |
中国药科大学 |
一类咪唑并吡嗪类化合物及其药物组合物和用途
|
|
US20170127985A1
(en)
|
2015-11-11 |
2017-05-11 |
Medtronic Minimed, Inc. |
Sensor set
|
|
WO2017103670A1
(en)
|
2015-12-14 |
2017-06-22 |
Zenith Epigenetics Lid. |
1h-imidazo[4,5-b]pyridinyl and 2-oxo-2,3-dihydro-1h-imidazo[4,5-b]pyridinyl heterocyclic bet bromodomain inhibitors
|
|
US10519151B2
(en)
|
2016-01-28 |
2019-12-31 |
Neomed Institute |
Substituted [1,2,4]triazolo[4,3-A]pyridines, their preparation and their use as pharmaceuticals
|
|
US20190040063A1
(en)
|
2016-02-05 |
2019-02-07 |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
Tricyclic compound for bromodomain-containing protein inhibitor and preparation pharmaceutical composition, and application thereof
|
|
CA3028689A1
(en)
|
2016-06-20 |
2017-12-28 |
Incyte Corporation |
Crystalline solid forms of a bet inhibitor
|
|
CN108069958A
(zh)
|
2016-11-10 |
2018-05-25 |
凯惠科技发展(上海)有限公司 |
一种含氮杂环类化合物、其制备方法、药物组合物及应用
|