JP2022092041A5 - - Google Patents
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- JP2022092041A5 JP2022092041A5 JP2022066294A JP2022066294A JP2022092041A5 JP 2022092041 A5 JP2022092041 A5 JP 2022092041A5 JP 2022066294 A JP2022066294 A JP 2022066294A JP 2022066294 A JP2022066294 A JP 2022066294A JP 2022092041 A5 JP2022092041 A5 JP 2022092041A5
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- Prior art keywords
- pharmaceutically acceptable
- compound
- acceptable salt
- immunoglobulin
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 150000001875 compounds Chemical class 0.000 claims 12
- 150000003839 salts Chemical class 0.000 claims 12
- 108060003951 Immunoglobulin Proteins 0.000 claims 7
- 102000018358 immunoglobulin Human genes 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 230000008685 targeting Effects 0.000 claims 4
- 230000003213 activating effect Effects 0.000 claims 3
- 108010074708 B7-H1 Antigen Proteins 0.000 claims 2
- 102100024216 Programmed cell death 1 ligand 1 Human genes 0.000 claims 2
- 102100040678 Programmed cell death protein 1 Human genes 0.000 claims 2
- 101710089372 Programmed cell death protein 1 Proteins 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 1
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 230000006907 apoptotic process Effects 0.000 claims 1
- 230000004663 cell proliferation Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 201000010536 head and neck cancer Diseases 0.000 claims 1
- 208000014829 head and neck neoplasm Diseases 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229960003301 nivolumab Drugs 0.000 claims 1
- 229960002621 pembrolizumab Drugs 0.000 claims 1
- BXNMTOQRYBFHNZ-UHFFFAOYSA-N resiquimod Chemical group C1=CC=CC2=C(N(C(COCC)=N3)CC(C)(C)O)C3=C(N)N=C21 BXNMTOQRYBFHNZ-UHFFFAOYSA-N 0.000 claims 1
- 229950010550 resiquimod Drugs 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 229940126622 therapeutic monoclonal antibody Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210248481.9 | 2012-07-18 | ||
| CN201210248481.9A CN103566377A (zh) | 2012-07-18 | 2012-07-18 | 癌症的靶向免疫治疗 |
| JP2019165174A JP7062298B2 (ja) | 2012-07-18 | 2019-09-11 | 標的免疫療法のための化合物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019165174A Division JP7062298B2 (ja) | 2012-07-18 | 2019-09-11 | 標的免疫療法のための化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022092041A JP2022092041A (ja) | 2022-06-21 |
| JP2022092041A5 true JP2022092041A5 (enExample) | 2023-01-18 |
Family
ID=49948284
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015521961A Expired - Fee Related JP6587936B2 (ja) | 2012-07-18 | 2013-07-16 | 標的免疫療法のための化合物 |
| JP2019165174A Expired - Fee Related JP7062298B2 (ja) | 2012-07-18 | 2019-09-11 | 標的免疫療法のための化合物 |
| JP2022066294A Pending JP2022092041A (ja) | 2012-07-18 | 2022-04-13 | 標的免疫療法のための化合物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015521961A Expired - Fee Related JP6587936B2 (ja) | 2012-07-18 | 2013-07-16 | 標的免疫療法のための化合物 |
| JP2019165174A Expired - Fee Related JP7062298B2 (ja) | 2012-07-18 | 2019-09-11 | 標的免疫療法のための化合物 |
Country Status (18)
| Country | Link |
|---|---|
| US (5) | US9878052B2 (enExample) |
| EP (1) | EP2874651B1 (enExample) |
| JP (3) | JP6587936B2 (enExample) |
| KR (1) | KR20150054768A (enExample) |
| CN (5) | CN112587671A (enExample) |
| AR (1) | AR091837A1 (enExample) |
| AU (1) | AU2013292894A1 (enExample) |
| BR (1) | BR112015001098A2 (enExample) |
| CA (1) | CA2878989A1 (enExample) |
| ES (1) | ES2953395T3 (enExample) |
| IL (1) | IL236772A0 (enExample) |
| IN (1) | IN2015DN00385A (enExample) |
| MX (1) | MX2015000821A (enExample) |
| RU (1) | RU2015105186A (enExample) |
| SG (1) | SG11201500399SA (enExample) |
| TW (1) | TW201408323A (enExample) |
| WO (1) | WO2014012479A1 (enExample) |
| ZA (1) | ZA201500318B (enExample) |
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