CN104411329A - 用于靶向免疫疗法的化合物 - Google Patents
用于靶向免疫疗法的化合物 Download PDFInfo
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- CN104411329A CN104411329A CN201380033552.6A CN201380033552A CN104411329A CN 104411329 A CN104411329 A CN 104411329A CN 201380033552 A CN201380033552 A CN 201380033552A CN 104411329 A CN104411329 A CN 104411329A
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Abstract
Description
抗体结构 | 示例性靶标 |
scFv | CC49,ERBB2,Ley |
双体抗体 | Ley和TAG-72 |
亲合体(Affibody) | ERBB2 |
微小抗体 | CEA,ERBB2 |
蛋白质–Fc | 血管生成素1,血管生成素2,VEGFR1,VEGFR2 |
完整IgG | CD20,CD33,EGFR,ERBB2,VEGF |
IgE和IgM | GM2 |
药物偶联物 | CD30,CD33和ERBB2 |
负载的纳米颗粒 | A33,EGFR和转铁蛋白 |
双特异性 | CD19–CD3,EPCAM–CD3,gp100–CD3 |
Claims (41)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
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CN201380033552.6A CN104411329A (zh) | 2012-07-18 | 2013-07-16 | 用于靶向免疫疗法的化合物 |
CN202211286144.9A CN115611988A (zh) | 2012-07-18 | 2013-07-16 | 用于靶向免疫疗法的化合物 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2012102484819 | 2012-07-18 | ||
CN201210248481.9A CN103566377A (zh) | 2012-07-18 | 2012-07-18 | 癌症的靶向免疫治疗 |
PCT/CN2013/079441 WO2014012479A1 (en) | 2012-07-18 | 2013-07-16 | Compounds for targeted immunotherapy |
CN201380033552.6A CN104411329A (zh) | 2012-07-18 | 2013-07-16 | 用于靶向免疫疗法的化合物 |
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