JP2020522489A - 養子細胞療法を用いる処置のための製造物品および方法 - Google Patents
養子細胞療法を用いる処置のための製造物品および方法 Download PDFInfo
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- JP2020522489A JP2020522489A JP2019566115A JP2019566115A JP2020522489A JP 2020522489 A JP2020522489 A JP 2020522489A JP 2019566115 A JP2019566115 A JP 2019566115A JP 2019566115 A JP2019566115 A JP 2019566115A JP 2020522489 A JP2020522489 A JP 2020522489A
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70514—CD4
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/248—IL-6
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70517—CD8
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/53—Colony-stimulating factor [CSF]
- G01N2333/535—Granulocyte CSF; Granulocyte-macrophage CSF
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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- Animal Behavior & Ethology (AREA)
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- Cell Biology (AREA)
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- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Hematology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
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- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Developmental Biology & Embryology (AREA)
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- Oncology (AREA)
- Mycology (AREA)
- Pathology (AREA)
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022136708A JP2022180389A (ja) | 2017-06-02 | 2022-08-30 | 養子細胞療法を用いる処置のための製造物品および方法 |
| JP2024223886A JP2025031805A (ja) | 2017-06-02 | 2024-12-19 | 養子細胞療法を用いる処置のための製造物品および方法 |
Applications Claiming Priority (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762514774P | 2017-06-02 | 2017-06-02 | |
| US62/514,774 | 2017-06-02 | ||
| US201762515530P | 2017-06-05 | 2017-06-05 | |
| US62/515,530 | 2017-06-05 | ||
| US201762521366P | 2017-06-16 | 2017-06-16 | |
| US62/521,366 | 2017-06-16 | ||
| US201762527000P | 2017-06-29 | 2017-06-29 | |
| US62/527,000 | 2017-06-29 | ||
| US201762549938P | 2017-08-24 | 2017-08-24 | |
| US62/549,938 | 2017-08-24 | ||
| US201762580425P | 2017-11-01 | 2017-11-01 | |
| US62/580,425 | 2017-11-01 | ||
| US201762593871P | 2017-12-01 | 2017-12-01 | |
| US62/593,871 | 2017-12-01 | ||
| US201762596764P | 2017-12-08 | 2017-12-08 | |
| US62/596,764 | 2017-12-08 | ||
| US201862614957P | 2018-01-08 | 2018-01-08 | |
| US62/614,957 | 2018-01-08 | ||
| PCT/US2018/035755 WO2018223101A1 (en) | 2017-06-02 | 2018-06-01 | Articles of manufacture and methods for treatment using adoptive cell therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022136708A Division JP2022180389A (ja) | 2017-06-02 | 2022-08-30 | 養子細胞療法を用いる処置のための製造物品および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020522489A true JP2020522489A (ja) | 2020-07-30 |
| JP2020522489A5 JP2020522489A5 (enExample) | 2021-08-12 |
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Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019566115A Pending JP2020522489A (ja) | 2017-06-02 | 2018-06-01 | 養子細胞療法を用いる処置のための製造物品および方法 |
| JP2022136708A Pending JP2022180389A (ja) | 2017-06-02 | 2022-08-30 | 養子細胞療法を用いる処置のための製造物品および方法 |
| JP2024223886A Pending JP2025031805A (ja) | 2017-06-02 | 2024-12-19 | 養子細胞療法を用いる処置のための製造物品および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
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| JP2022136708A Pending JP2022180389A (ja) | 2017-06-02 | 2022-08-30 | 養子細胞療法を用いる処置のための製造物品および方法 |
| JP2024223886A Pending JP2025031805A (ja) | 2017-06-02 | 2024-12-19 | 養子細胞療法を用いる処置のための製造物品および方法 |
Country Status (12)
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|---|---|
| US (5) | US11413310B2 (enExample) |
| EP (1) | EP3630132A1 (enExample) |
| JP (3) | JP2020522489A (enExample) |
| KR (1) | KR20200054160A (enExample) |
| CN (2) | CN111225675B (enExample) |
| AU (2) | AU2018275894B2 (enExample) |
| BR (1) | BR112019025403A2 (enExample) |
| CA (1) | CA3065120A1 (enExample) |
| IL (2) | IL270982B1 (enExample) |
| MX (2) | MX2019014268A (enExample) |
| PH (1) | PH12019502661A1 (enExample) |
| WO (1) | WO2018223101A1 (enExample) |
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| US12188004B2 (en) | 2012-05-08 | 2025-01-07 | The Johns Hopkins University | Cancer immunotherapy using transfusions of allogeneic, tumor-specific CD4+ T cells |
| BR112014027957A8 (pt) | 2012-05-08 | 2018-01-16 | Univ Johns Hopkins | métodos e composições para infusão de populações selecionadas de enxerto transitório de linfócitos alogênicos para tratar câncer" |
| CN117427091A (zh) | 2014-10-20 | 2024-01-23 | 朱诺治疗学股份有限公司 | 用于过继细胞治疗中的给药的组合物和方法 |
| CA3008162A1 (en) * | 2014-12-15 | 2016-06-23 | The Regents Of The University Of California | Bispecific or-gate chimeric antigen receptor responsive to cd19 and cd20 |
| MA43377A (fr) | 2015-12-04 | 2021-05-19 | Hutchinson Fred Cancer Res | Méthodes et compositions liées à la toxicité associée à la thérapie cellulaire |
| US20200078400A1 (en) | 2016-12-03 | 2020-03-12 | Juno Therapeutics, Inc. | Methods for determining car-t cells dosing |
| CA3053539A1 (en) * | 2017-02-27 | 2018-08-30 | Juno Therapeutics, Inc. | Compositions, articles of manufacture and methods related to dosing in cell therapy |
| CN111225675B (zh) | 2017-06-02 | 2024-05-03 | 朱诺治疗学股份有限公司 | 使用过继细胞疗法治疗的制品和方法 |
| MA50855A (fr) | 2017-11-01 | 2020-09-09 | Juno Therapeutics Inc | Procédé de génération de compositions thérapeutiques de cellules modifiées |
| WO2019089848A1 (en) | 2017-11-01 | 2019-05-09 | Juno Therapeutics, Inc. | Methods associated with tumor burden for assessing response to a cell therapy |
| US12031975B2 (en) | 2017-11-01 | 2024-07-09 | Juno Therapeutics, Inc. | Methods of assessing or monitoring a response to a cell therapy |
| KR20200116081A (ko) * | 2017-12-01 | 2020-10-08 | 주노 쎄러퓨티크스 인코퍼레이티드 | 유전자 조작된 세포의 투약 및 조절 방법 |
| EP3720480A2 (en) | 2017-12-08 | 2020-10-14 | Juno Therapeutics, Inc. | Phenotypic markers for cell therapy and related methods |
| WO2019204462A2 (en) | 2018-04-17 | 2019-10-24 | Celldex Therapeutics, Inc. | Anti-cd27 and anti-pd-l1 antibodies and bispecific constructs |
| CN112292080A (zh) * | 2018-05-18 | 2021-01-29 | 纳诺碧欧系统股份公司 | 生物流体样品的收集和处理 |
| SG11202101204TA (en) | 2018-08-09 | 2021-03-30 | Juno Therapeutics Inc | Processes for generating engineered cells and compositions thereof |
| CA3117978A1 (en) | 2018-11-08 | 2020-05-14 | Juno Therapeutics, Inc. | Methods and combinations for treatment and t cell modulation |
| BR112021010354A2 (pt) * | 2018-11-30 | 2021-11-03 | Juno Therapeutics Inc | Métodos para o tratamento usando terapia celular adotiva |
| WO2020123444A1 (en) * | 2018-12-11 | 2020-06-18 | Celldex Therapeutics, Inc. | Methods of using cd27 antibodies as conditioning treatment for adoptive cell therapy |
| WO2020180882A1 (en) | 2019-03-05 | 2020-09-10 | Nkarta, Inc. | Cd19-directed chimeric antigen receptors and uses thereof in immunotherapy |
| AU2020267378B2 (en) * | 2019-05-03 | 2025-01-30 | Kite Pharma, Inc. | Methods of administering chimeric antigen receptor immunotherapy |
| IL292667B1 (en) * | 2019-11-07 | 2026-02-01 | Juno Therapeutics Inc | Combination of T-cell therapy and (s)-3-[4-(4-morpholin-4-ylmethyl-benzyloxy)-l-oxo-3,l-dihydro-isoindol-2-yl]-piperidine-6,2-dione |
| WO2021113770A1 (en) * | 2019-12-06 | 2021-06-10 | Juno Therapeutics, Inc. | Methods related to toxicity and response associated with cell therapy for treating b cell malignancies |
| US20230100653A1 (en) | 2020-02-10 | 2023-03-30 | The Johns Hopkins University | Cancer immunotherapy using transfusions of allogeneic, tumor-specific cd4+ t cells |
| IL295384B1 (en) * | 2020-02-12 | 2026-04-01 | Juno Therapeutics Inc | T-cell preparations with chimeric antigen receptor directed against CD19 and methods and uses thereof |
| US12431247B2 (en) * | 2020-03-11 | 2025-09-30 | National Taiwan University | Systems and methods for prognosis prediction of acute myeloid leukemia patients |
| AU2021245936A1 (en) * | 2020-04-03 | 2022-11-03 | Trishula Therapeutics, Inc. | Combination therapy involving anti-CD39 antibodies and adoptive cell therapy |
| IL297147B1 (en) * | 2020-04-10 | 2026-05-01 | Juno Therapeutics Inc | Methods and uses related to engineered cell therapy with a chimeric antigen receptor directed against a B-cell maturation antigen |
| WO2021231657A1 (en) | 2020-05-13 | 2021-11-18 | Juno Therapeutics, Inc. | Methods of identifying features associated with clinical response and uses thereof |
| CA3183395A1 (en) * | 2020-06-25 | 2021-12-30 | Paul William FINNEGAN | Endothelial cells for mitigation of chemotherapy-induced toxicity |
| GB2598894A (en) * | 2020-09-10 | 2022-03-23 | Oxford Nanoimaging Ltd | Cell classification algorithm |
| US12496303B2 (en) | 2020-10-19 | 2025-12-16 | Washington University | Conditioning agents for use in allogeneic hematopoietic stem cell transplantation |
| WO2022187517A1 (en) * | 2021-03-04 | 2022-09-09 | New York University | Methods of modulating neuronal and oligodenrocyte survival |
| CA3217687A1 (en) * | 2021-05-11 | 2022-11-17 | Muhammad S. AKRAM | Methods of minimizing neurotoxicity associated with chimeric antigen receptor (car) t cell therapy |
| CN113699123B (zh) * | 2021-10-28 | 2022-01-25 | 旦旦生物科技(上海)有限公司 | 靶向超敏广谱溶瘤病毒制备及应用 |
| US20250345432A1 (en) | 2022-05-25 | 2025-11-13 | Celgene Corporation | Method for predicting response to a t cell therapy |
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| WO2016164731A2 (en) * | 2015-04-08 | 2016-10-13 | Novartis Ag | Cd20 therapies, cd22 therapies, and combination therapies with a cd19 chimeric antigen receptor (car) - expressing cell |
| WO2016191756A1 (en) * | 2015-05-28 | 2016-12-01 | Adrian Bot | Methods of conditioning patients for t cell therapy |
| JP2017512484A (ja) * | 2014-04-10 | 2017-05-25 | シアトル チルドレンズ ホスピタル, ディービーエー シアトル チルドレンズ リサーチ インスティテュート | 特定の組成を有する遺伝子により改変されたt細胞製剤 |
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