JP2018522563A5 - - Google Patents

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JP2018522563A5
JP2018522563A5 JP2018505716A JP2018505716A JP2018522563A5 JP 2018522563 A5 JP2018522563 A5 JP 2018522563A5 JP 2018505716 A JP2018505716 A JP 2018505716A JP 2018505716 A JP2018505716 A JP 2018505716A JP 2018522563 A5 JP2018522563 A5 JP 2018522563A5
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amino acid
seq
fix
fusion protein
domain
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JP2018505716A
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JP6909203B2 (ja
JP2018522563A (ja
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Priority claimed from PCT/US2016/045401 external-priority patent/WO2017024060A1/en
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JP2018505716A 2015-08-03 2016-08-03 第ix因子融合タンパク質及びそれらの製造方法及び使用方法 Active JP6909203B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562200590P 2015-08-03 2015-08-03
US62/200,590 2015-08-03
US201662281993P 2016-01-22 2016-01-22
US62/281,993 2016-01-22
PCT/US2016/045401 WO2017024060A1 (en) 2015-08-03 2016-08-03 Factor ix fusion proteins and methods of making and using same

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JP2021034342A Division JP2021078526A (ja) 2015-08-03 2021-03-04 第ix因子融合タンパク質及びそれらの製造方法及び使用方法

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JP2018522563A JP2018522563A (ja) 2018-08-16
JP2018522563A5 true JP2018522563A5 (enExample) 2019-09-12
JP6909203B2 JP6909203B2 (ja) 2021-07-28

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JP2018505716A Active JP6909203B2 (ja) 2015-08-03 2016-08-03 第ix因子融合タンパク質及びそれらの製造方法及び使用方法
JP2021034342A Withdrawn JP2021078526A (ja) 2015-08-03 2021-03-04 第ix因子融合タンパク質及びそれらの製造方法及び使用方法
JP2022145321A Active JP7418519B2 (ja) 2015-08-03 2022-09-13 第ix因子融合タンパク質及びそれらの製造方法及び使用方法

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JP2021034342A Withdrawn JP2021078526A (ja) 2015-08-03 2021-03-04 第ix因子融合タンパク質及びそれらの製造方法及び使用方法
JP2022145321A Active JP7418519B2 (ja) 2015-08-03 2022-09-13 第ix因子融合タンパク質及びそれらの製造方法及び使用方法

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US (2) US10745680B2 (enExample)
EP (1) EP3331608A4 (enExample)
JP (3) JP6909203B2 (enExample)
KR (1) KR102659212B1 (enExample)
CN (1) CN108472337B (enExample)
AU (1) AU2016301303B2 (enExample)
BR (1) BR112018002150A2 (enExample)
CA (1) CA2994547A1 (enExample)
CL (1) CL2018000302A1 (enExample)
CO (1) CO2018002196A2 (enExample)
EA (1) EA201890423A1 (enExample)
HK (1) HK1248162A1 (enExample)
IL (1) IL257231B (enExample)
MX (1) MX2018001497A (enExample)
PH (1) PH12018500252A1 (enExample)
TW (1) TWI741992B (enExample)
UA (1) UA126016C2 (enExample)
WO (1) WO2017024060A1 (enExample)

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AU2020258483A1 (en) 2019-04-17 2021-11-11 Evox Therapeutics, Ltd. Compositions of exosomes and AAV
CN112175088B (zh) * 2019-07-02 2023-03-28 江苏晟斯生物制药有限公司 改进的fix融合蛋白、缀合物及其应用
TW202126284A (zh) 2019-09-30 2021-07-16 美商百歐維拉提夫治療公司 慢病毒載體配製物
CN111647625A (zh) * 2019-12-25 2020-09-11 深圳三智医学科技有限公司 一种提高人凝血因子ix表达水平的方法
US11213581B2 (en) 2020-04-10 2022-01-04 Akston Biosciences Corporation Antigen specific immunotherapy for COVID-19 fusion proteins and methods of use
WO2021262963A1 (en) 2020-06-24 2021-12-30 Bioverativ Therapeutics Inc. Methods for the removal of free factor viii from preparations of lentiviral vectors modified to express said protein
GB202009928D0 (en) * 2020-06-29 2020-08-12 Freeline Therapeutics Ltd Method
CN113817759B (zh) * 2020-07-10 2023-06-02 南京吉迈生物技术有限公司 修饰的因子ix、组合物、方法及其在基因治疗中的应用
US20240293516A1 (en) * 2021-07-01 2024-09-05 CSL Behring Lengnau AG Factor ix subcutaneous administration with enhanced safety
CN114989307B (zh) * 2022-05-11 2023-08-01 华兰生物工程股份有限公司 一种重组人凝血因子Ⅷ-Fc融合蛋白及制备方法

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