JP2015519313A5 - - Google Patents
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- Publication number
- JP2015519313A5 JP2015519313A5 JP2015507425A JP2015507425A JP2015519313A5 JP 2015519313 A5 JP2015519313 A5 JP 2015519313A5 JP 2015507425 A JP2015507425 A JP 2015507425A JP 2015507425 A JP2015507425 A JP 2015507425A JP 2015519313 A5 JP2015519313 A5 JP 2015519313A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- pharmaceutical composition
- composition according
- amino acid
- fviii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12165296.0 | 2012-04-24 | ||
| EP12165296 | 2012-04-24 | ||
| US201261641439P | 2012-05-02 | 2012-05-02 | |
| US61/641,439 | 2012-05-02 | ||
| EP13150575 | 2013-01-09 | ||
| EP13150575.2 | 2013-01-09 | ||
| US201361752614P | 2013-01-15 | 2013-01-15 | |
| US61/752,614 | 2013-01-15 | ||
| PCT/EP2013/055107 WO2013160005A1 (en) | 2012-04-24 | 2013-03-13 | Pharmaceutical composition suitable for treatment of haemophilia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015519313A JP2015519313A (ja) | 2015-07-09 |
| JP2015519313A5 true JP2015519313A5 (enExample) | 2016-04-14 |
Family
ID=49482214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015507425A Withdrawn JP2015519313A (ja) | 2012-04-24 | 2013-03-13 | 血友病の治療に適する医薬組成物 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20150045303A1 (enExample) |
| EP (1) | EP2841091A1 (enExample) |
| JP (1) | JP2015519313A (enExample) |
| CN (1) | CN104411323A (enExample) |
| WO (1) | WO2013160005A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2771999A1 (en) | 2009-08-24 | 2011-03-10 | Amunix Operating Inc. | Coagulation factor vii compositions and methods of making and using same |
| CN111548418A (zh) | 2012-02-15 | 2020-08-18 | 比奥贝拉蒂治疗公司 | 因子viii组合物及其制备和使用方法 |
| WO2013123457A1 (en) | 2012-02-15 | 2013-08-22 | Biogen Idec Ma Inc. | Recombinant factor viii proteins |
| US10548953B2 (en) | 2013-08-14 | 2020-02-04 | Bioverativ Therapeutics Inc. | Factor VIII-XTEN fusions and uses thereof |
| EA201691111A1 (ru) | 2014-01-10 | 2017-01-30 | Байоджен Ма Инк. | Химерные белки фактора viii и их применение |
| AR101060A1 (es) * | 2014-02-12 | 2016-11-23 | Novo Nordisk As | Conjugados de fviii |
| BR112016026842A2 (pt) | 2014-06-06 | 2017-12-12 | Octapharma Ag | preparação compreendendo fator viii e peptídeos de fator de von willebrand |
| WO2016198521A1 (en) | 2015-06-10 | 2016-12-15 | Novo Nordisk A/S | Fviii fusion proteins |
| UA126016C2 (uk) | 2015-08-03 | 2022-08-03 | Біовератів Терапеутікс Інк. | Злитий білок фактора іх |
| EP3205665A1 (en) * | 2016-02-11 | 2017-08-16 | Octapharma AG | Method of separating factor viii from blood products |
| JP2020504082A (ja) * | 2016-11-11 | 2020-02-06 | ツェー・エス・エル・ベーリング・レングナウ・アクチエンゲゼルシャフト | 血液凝固障害の処置又は予防における血管外投与のための切断型フォン・ヴィルブランド因子ポリペプチド |
| KR20190090827A (ko) | 2016-12-02 | 2019-08-02 | 바이오버라티브 테라퓨틱스 인크. | 키메라 응고 인자를 사용해 혈우병성 관절증을 치료하는 방법 |
| DK3641800T5 (da) | 2017-06-22 | 2024-08-26 | CSL Behring Lengnau AG | Modulation af fviii immunogenicitet ved trunkeret vwf |
| CN108918235A (zh) * | 2018-05-16 | 2018-11-30 | 绍兴文理学院 | 一种肿瘤淋巴结离体标本的固定处理方法 |
| CN108753910A (zh) * | 2018-05-16 | 2018-11-06 | 浙江思格医疗科技有限公司 | 一种消化液 |
| KR102914074B1 (ko) | 2018-05-18 | 2026-01-16 | 바이오버라티브 테라퓨틱스 인크. | A형 혈우병의 치료 방법 |
| EP3870206A4 (en) * | 2018-10-23 | 2023-04-26 | The Children's Hospital Of Philadelphia | COMPOSITIONS AND METHODS OF MODULATION OF FACTOR VIII FUNCTION |
| WO2021001522A1 (en) * | 2019-07-04 | 2021-01-07 | CSL Behring Lengnau AG | A truncated von willebrand factor (vwf) for increasing the in vitro stability of coagulation factor viii |
| WO2021032646A1 (en) | 2019-08-16 | 2021-02-25 | Octapharma Ag | Stabilizing buffer for factor viii and vwf |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5952198A (en) * | 1995-05-04 | 1999-09-14 | Bayer Corporation | Production of recombinant Factor VIII in the presence of liposome-like substances of mixed composition |
| EP2292273A3 (en) | 2001-10-10 | 2011-11-23 | BioGeneriX AG | Remodeling and glycoconjugation of peptides |
| US20080070251A1 (en) * | 2006-06-30 | 2008-03-20 | Kaufman Randal J | Method of Producing Factor VIII Proteins by Recombinant Methods |
| PL2167117T3 (pl) * | 2007-06-13 | 2013-01-31 | Csl Behring Gmbh | Zastosowanie stabilizowanego VWP preparatu FVIII do podawania pozanaczyniowego w terapii i profilaktyce zaburzeń krzepliwości krwi |
| US20130189239A1 (en) * | 2008-02-27 | 2013-07-25 | Novo Nordisk A/S | Conjugated Factor VIII Molecules |
| EP2352515A4 (en) | 2008-11-03 | 2012-04-25 | Bayer Healthcare Llc | METHOD FOR TREATING HEMOPHILIA |
| GB0911870D0 (en) * | 2009-07-08 | 2009-08-19 | Ucl Business Plc | Optimised coding sequence and promoter |
| WO2011101284A1 (en) | 2010-02-16 | 2011-08-25 | Novo Nordisk A/S | Factor viii fusion protein |
| JP2013532176A (ja) * | 2010-07-15 | 2013-08-15 | ノヴォ ノルディスク アー／エス | 安定化させた第ｖｉｉｉ因子バリアント |
| CN104788557A (zh) | 2010-09-15 | 2015-07-22 | 诺沃—诺迪斯克有限公司 | 具有减少的细胞摄取的因子viii变体 |
-
2013
- 2013-03-13 US US14/396,833 patent/US20150045303A1/en not_active Abandoned
- 2013-03-13 CN CN201380033402.5A patent/CN104411323A/zh not_active Withdrawn
- 2013-03-13 WO PCT/EP2013/055107 patent/WO2013160005A1/en not_active Ceased
- 2013-03-13 EP EP13713368.2A patent/EP2841091A1/en not_active Withdrawn
- 2013-03-13 JP JP2015507425A patent/JP2015519313A/ja not_active Withdrawn
-
2015
- 2015-11-06 US US14/934,196 patent/US20160120954A1/en not_active Abandoned
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