JP2018526987A5 - - Google Patents

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Publication number
JP2018526987A5
JP2018526987A5 JP2018504942A JP2018504942A JP2018526987A5 JP 2018526987 A5 JP2018526987 A5 JP 2018526987A5 JP 2018504942 A JP2018504942 A JP 2018504942A JP 2018504942 A JP2018504942 A JP 2018504942A JP 2018526987 A5 JP2018526987 A5 JP 2018526987A5
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JP
Japan
Prior art keywords
amino acid
seq
polypeptide
acid residue
acid residues
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JP2018504942A
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English (en)
Japanese (ja)
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JP6903633B2 (ja
JP2018526987A (ja
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Priority claimed from PCT/CN2016/090800 external-priority patent/WO2017016430A1/zh
Publication of JP2018526987A publication Critical patent/JP2018526987A/ja
Publication of JP2018526987A5 publication Critical patent/JP2018526987A5/ja
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Publication of JP6903633B2 publication Critical patent/JP6903633B2/ja
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JP2018504942A 2015-07-27 2016-07-21 腫瘍抑制ペプチド Active JP6903633B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201510446747 2015-07-27
CN201510446747.4 2015-07-27
PCT/CN2016/090800 WO2017016430A1 (zh) 2015-07-27 2016-07-21 一种肿瘤抑制肽

Publications (3)

Publication Number Publication Date
JP2018526987A JP2018526987A (ja) 2018-09-20
JP2018526987A5 true JP2018526987A5 (enExample) 2019-08-08
JP6903633B2 JP6903633B2 (ja) 2021-07-14

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ID=57883958

Family Applications (1)

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JP2018504942A Active JP6903633B2 (ja) 2015-07-27 2016-07-21 腫瘍抑制ペプチド

Country Status (5)

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US (1) US10351613B2 (enExample)
EP (1) EP3330285B1 (enExample)
JP (1) JP6903633B2 (enExample)
CN (17) CN113912705B (enExample)
WO (1) WO2017016430A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113912705B (zh) * 2015-07-27 2023-12-22 上海贺普药业股份有限公司 一种肿瘤抑制肽
CN113244370A (zh) * 2020-02-13 2021-08-13 珠海市藤栢医药有限公司 一种预防和/或治疗神经母细胞瘤的多肽药物及其用途
CN115991739B (zh) * 2021-12-20 2023-10-20 珠海市藤栢医药有限公司 一种抗肿瘤的多肽及其制备方法和应用
CN117801060A (zh) * 2022-09-26 2024-04-02 深圳碳云智肽药物科技有限公司 一种抗肿瘤多肽及应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3840262B2 (ja) * 1995-10-23 2006-11-01 ザ チルドレンズ メディカル センター コーポレイション 治療用の抗血管新生組成物および方法
US5854205A (en) * 1995-10-23 1998-12-29 The Children's Medical Center Corporation Therapeutic antiangiogenic compositions and methods
US6174861B1 (en) * 1996-10-22 2001-01-16 The Children's Medical Center Corporation Methods of inhibiting angiogenesis via increasing in vivo concentrations of endostatin protein
US6825167B1 (en) * 2000-04-03 2004-11-30 Regents Of The University Of Minnesota Genetic modification of endostatin
CN1239516C (zh) * 2002-02-08 2006-02-01 中国医学科学院基础医学研究所 肿瘤坏死因子相关细胞凋亡诱导配体胞外区突变多肽及其制法与用途
BR0308090A (pt) * 2002-03-01 2006-04-11 Univ Tulane conjugados de agentes citotóxicos ou terapêuticos e peptìdios biologicamente ativos
US20040091465A1 (en) * 2002-06-26 2004-05-13 Zachary Yim Therapeutic antiangiogenic compositions and methods
US7078485B2 (en) * 2002-12-05 2006-07-18 Yantai Medgenn Ltd. N-terminal modified recombinant human endostatin and its production
US7524811B2 (en) * 2003-08-29 2009-04-28 Children's Medical Center Corporation Anti-angiogenic peptides from the N-terminus of endostatin
CN1875104A (zh) * 2003-08-29 2006-12-06 儿童医学中心公司 来自内皮抑素n-末端的抗血管生成肽
EP1687426B1 (en) * 2003-08-29 2008-07-16 Children's Medical Center Corporation Antiangiogenicpeptides for treating or preventing endometriosis
ES2325344B1 (es) * 2004-11-02 2010-06-09 Univ Madrid Autonoma Inhibidores de angiogenesis multifuncionales y multivalentes.
CN100586961C (zh) * 2006-05-16 2010-02-03 中国人民解放军军事医学科学院野战输血研究所 对肿瘤细胞具有抑制作用的融合蛋白及其编码基因与应用
CN101062954A (zh) * 2006-05-16 2007-10-31 中国人民解放军军事医学科学院野战输血研究所 具有抗血管生成作用的融合蛋白及其编码基因与应用
CA2683463A1 (en) * 2007-04-11 2008-10-23 Gene Signal International Sa Anti-tumor variants and fragments of protein 497c, and uses thereof
CN101096671A (zh) * 2007-06-01 2008-01-02 徐寒梅 血管生成抑制剂hm-x及其制备方法和应用
EP2173377B1 (en) * 2007-06-26 2017-11-29 University of Miami Antibody-endostatin fusion protein and its variants
CN102924578A (zh) * 2011-08-09 2013-02-13 哈药集团技术中心 抗肿瘤多肽及其制备方法和抗肿瘤应用
EP2561888A1 (en) * 2011-08-23 2013-02-27 Deutsches Krebsforschungszentrum Protein comprising NC-1 for treating angiogenesis-related diseases
CN113912705B (zh) * 2015-07-27 2023-12-22 上海贺普药业股份有限公司 一种肿瘤抑制肽

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