JP2018021037A5 - - Google Patents

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Publication number
JP2018021037A5
JP2018021037A5 JP2017148823A JP2017148823A JP2018021037A5 JP 2018021037 A5 JP2018021037 A5 JP 2018021037A5 JP 2017148823 A JP2017148823 A JP 2017148823A JP 2017148823 A JP2017148823 A JP 2017148823A JP 2018021037 A5 JP2018021037 A5 JP 2018021037A5
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JP
Japan
Prior art keywords
recombinant fsh
pharmaceutical composition
cell line
sialylation
sialyltransferase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017148823A
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English (en)
Japanese (ja)
Other versions
JP2018021037A (ja
JP6762916B2 (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2018021037A publication Critical patent/JP2018021037A/ja
Publication of JP2018021037A5 publication Critical patent/JP2018021037A5/ja
Priority to JP2019194476A priority Critical patent/JP7316905B2/ja
Application granted granted Critical
Publication of JP6762916B2 publication Critical patent/JP6762916B2/ja
Priority to JP2021175403A priority patent/JP2022031652A/ja
Priority to JP2023215339A priority patent/JP2024038000A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2017148823A 2008-04-16 2017-08-01 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ Active JP6762916B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2019194476A JP7316905B2 (ja) 2008-04-16 2019-10-25 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ
JP2021175403A JP2022031652A (ja) 2008-04-16 2021-10-27 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ
JP2023215339A JP2024038000A (ja) 2008-04-16 2023-12-21 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US4542408P 2008-04-16 2008-04-16
US61/045,424 2008-04-16
EP08251528 2008-04-25
EP08251528.9 2008-04-25

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2016198588A Division JP6486310B2 (ja) 2008-04-16 2016-10-07 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019194476A Division JP7316905B2 (ja) 2008-04-16 2019-10-25 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ

Publications (3)

Publication Number Publication Date
JP2018021037A JP2018021037A (ja) 2018-02-08
JP2018021037A5 true JP2018021037A5 (https=) 2018-11-08
JP6762916B2 JP6762916B2 (ja) 2020-09-30

Family

ID=39717519

Family Applications (7)

Application Number Title Priority Date Filing Date
JP2011504527A Pending JP2011519359A (ja) 2008-04-16 2009-04-16 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ
JP2014262056A Pending JP2015120696A (ja) 2008-04-16 2014-12-25 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ
JP2016198588A Active JP6486310B2 (ja) 2008-04-16 2016-10-07 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ
JP2017148823A Active JP6762916B2 (ja) 2008-04-16 2017-08-01 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ
JP2019194476A Active JP7316905B2 (ja) 2008-04-16 2019-10-25 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ
JP2021175403A Pending JP2022031652A (ja) 2008-04-16 2021-10-27 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ
JP2023215339A Pending JP2024038000A (ja) 2008-04-16 2023-12-21 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP2011504527A Pending JP2011519359A (ja) 2008-04-16 2009-04-16 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ
JP2014262056A Pending JP2015120696A (ja) 2008-04-16 2014-12-25 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ
JP2016198588A Active JP6486310B2 (ja) 2008-04-16 2016-10-07 アルファ２，３−およびアルファ２，６−シアリル化を含む組換えｆｓｈ

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2019194476A Active JP7316905B2 (ja) 2008-04-16 2019-10-25 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ
JP2021175403A Pending JP2022031652A (ja) 2008-04-16 2021-10-27 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ
JP2023215339A Pending JP2024038000A (ja) 2008-04-16 2023-12-21 アルファ２，３－およびアルファ２，６－シアリル化を含む組換えｆｓｈ

Country Status (29)

Country Link
US (6) US8951967B2 (https=)
EP (7) EP2722339A1 (https=)
JP (7) JP2011519359A (https=)
KR (5) KR20170110741A (https=)
CN (3) CN105906703A (https=)
AR (1) AR071479A1 (https=)
AU (5) AU2009237479B2 (https=)
BR (1) BRPI0910461B8 (https=)
CA (1) CA2725257A1 (https=)
CY (1) CY1115413T1 (https=)
DK (6) DK2268666T3 (https=)
ES (5) ES2629392T3 (https=)
FI (4) FI4015527T3 (https=)
FR (3) FR17C1020I2 (https=)
HR (5) HRP20140535T1 (https=)
HU (9) HUE068565T2 (https=)
IL (2) IL208538A (https=)
LT (8) LT3045471T (https=)
MX (3) MX348622B (https=)
NO (4) NO2017025I1 (https=)
NZ (1) NZ588381A (https=)
PL (6) PL3144318T3 (https=)
PT (6) PT3144318T (https=)
RU (3) RU2537268C2 (https=)
SA (1) SA109300228B1 (https=)
SI (6) SI2268666T1 (https=)
TW (1) TWI488640B (https=)
WO (1) WO2009127826A1 (https=)
ZA (1) ZA201007373B (https=)

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TWI488640B (zh) 2008-04-16 2015-06-21 菲瑞茵國際中心股份有限公司 藥學製劑
TWI532495B (zh) * 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 藥學製劑
EP2417982A1 (en) 2010-07-30 2012-02-15 Ferring B.V. Stabilization of gonadotropins
WO2012016576A1 (en) * 2010-08-04 2012-02-09 Glycotope Gmbh Improved recombinant human follicle-stimulating hormone
EP2621517B2 (en) 2010-09-29 2023-10-11 Ferring B.V. Composition for use in treating infertility
WO2012050175A1 (ja) 2010-10-15 2012-04-19 日本ケミカルリサーチ株式会社 糖鎖の非還元末端がマンノース残基である糖蛋白質の製造方法
US9757469B2 (en) 2011-03-31 2017-09-12 Ferring B.V. Pharmaceutical preparation
EP2717904A1 (en) 2011-06-06 2014-04-16 Ferring BV Pharmaceutical preparation comprising recombinant fsh
JO3092B1 (ar) 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
WO2013093760A2 (en) * 2011-12-19 2013-06-27 Grifols, S.A. Compositions, methods, and kits for preparing sialylated recombinant proteins
WO2013161958A1 (ja) * 2012-04-27 2013-10-31 日本ケミカルリサーチ株式会社 新規な発現ベクター
EP2824176A1 (en) * 2013-07-11 2015-01-14 Siamed'xpress Methods for producing sialylated therapeutic proteins
JP6652334B2 (ja) 2014-05-31 2020-02-19 Ｊｃｒファーマ株式会社 ウリジンとｎ−アセチル−ｄ−マンノサミンとを含有する培地
EP3237608B1 (en) * 2014-12-22 2019-10-09 F. Hoffmann-La Roche AG Cmp-dependent sialidase activity
EP3662925B1 (en) 2015-04-17 2021-04-07 Ferring B.V. Composition comprising fsh for treatment of infertility
WO2016207353A1 (en) * 2015-06-26 2016-12-29 Ferring B.V. Methods of purification and/or viral inactivation
EP3205719A1 (en) * 2016-02-15 2017-08-16 CEVEC Pharmaceuticals GmbH Cell lines for producing recombinant glycoproteins with di-antennary n-glycans, methods using the same, and recombinant glycoproteins
GB201603280D0 (en) 2016-02-24 2016-04-13 Ferring Bv Stable liquid gonadotropin formulation
EP3382014A1 (en) * 2017-03-29 2018-10-03 CEVEC Pharmaceuticals GmbH Recombinant glycoproteins with reduced antennary fucosylation
EP3441471A1 (en) 2017-08-08 2019-02-13 CEVEC Pharmaceuticals GmbH Use of constitutively active variants of growth factor receptors as selection makers for the generation of stable producer cell lines
US11744879B2 (en) 2017-09-01 2023-09-05 Ferring B.V. Recombinant FSH composition for controlled ovarian stimulation
RS66871B1 (sr) 2018-04-30 2025-06-30 Ferring Bv Kompozicija za kontrolisanu stimulaciju jajnika
TWI846743B (zh) 2018-10-17 2024-07-01 荷蘭商菲林公司 用於控制性卵巢刺激之組成物及方法
WO2021081670A1 (en) * 2019-11-01 2021-05-06 The University Of British Columbia Compositions and methods for sialylated mucin-type o-glycosylation of therapeutic proteins
TW202237173A (zh) 2020-12-09 2022-10-01 荷蘭商菲林公司 用於受控的卵巢刺激之組成物及方法
AU2022451605A1 (en) 2022-04-01 2024-09-26 Ferring B.V. Mixed protocol for treatment of infertility
WO2023227761A1 (en) 2022-05-26 2023-11-30 Ferring B.V. Compositions and methods for treatment of infertility in males
AU2023302100A1 (en) 2022-07-08 2025-01-02 Ferring B.V. Compositions and methods for intrauterine insemination (iui)
AR133300A1 (es) 2023-07-20 2025-09-17 Ferring Bv Micropartículas cargadas con fármaco de liberación prolongada

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US5541083A (en) 1989-10-24 1996-07-30 The Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
SI0833934T2 (sl) 1995-06-15 2013-04-30 Crucell Holland B.V. Pakirni sistemi za humani rekombinantni adenovirus za uporabo v genski terapiji
JP3559652B2 (ja) * 1996-06-25 2004-09-02 グローリー工業株式会社 売上精算システムの管理装置
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TWI532495B (zh) 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 藥學製劑
EP2417982A1 (en) 2010-07-30 2012-02-15 Ferring B.V. Stabilization of gonadotropins
US8790322B2 (en) 2010-08-03 2014-07-29 King Saud University Stoma coat
WO2012016576A1 (en) 2010-08-04 2012-02-09 Glycotope Gmbh Improved recombinant human follicle-stimulating hormone
EP2621517B2 (en) 2010-09-29 2023-10-11 Ferring B.V. Composition for use in treating infertility
US9757469B2 (en) 2011-03-31 2017-09-12 Ferring B.V. Pharmaceutical preparation
EP2717904A1 (en) 2011-06-06 2014-04-16 Ferring BV Pharmaceutical preparation comprising recombinant fsh
JO3092B1 (ar) 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
AR100132A1 (es) 2014-04-18 2016-09-14 Glycotope Gmbh Un método para hiperestimulación ovárica controlada para estimular el desarrollo de múltiples folículos ováricos en un sujeto femenino

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