KR20160056960A - α2,3- 및 α2,6-시알화를 포함하는 재조합 ＦＳＨ - Google Patents
α2,3- 및 α2,6-시알화를 포함하는 재조합 ＦＳＨ Download PDFInfo
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- KR20160056960A KR20160056960A KR1020167012148A KR20167012148A KR20160056960A KR 20160056960 A KR20160056960 A KR 20160056960A KR 1020167012148 A KR1020167012148 A KR 1020167012148A KR 20167012148 A KR20167012148 A KR 20167012148A KR 20160056960 A KR20160056960 A KR 20160056960A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
- C12Y204/99006—N-Acetyllactosaminide alpha-2,3-sialyltransferase (2.4.99.6)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4542408P | 2008-04-16 | 2008-04-16 | |
| US61/045,424 | 2008-04-16 | ||
| EP08251528.9 | 2008-04-25 | ||
| EP08251528 | 2008-04-25 | ||
| PCT/GB2009/000978 WO2009127826A1 (en) | 2008-04-16 | 2009-04-16 | Recombinant fsh including alpha 2,3- and alpha 2,6-sialylation |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020107025581A Division KR101622944B1 (ko) | 2008-04-16 | 2009-04-16 | α2,3- 및 α2,6-시알화를 포함하는 재조합 ＦＳＨ |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020177026920A Division KR20170110741A (ko) | 2008-04-16 | 2009-04-16 | α2,3- 및 α2,6-시알화를 포함하는 재조합 ＦＳＨ |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20160056960A true KR20160056960A (ko) | 2016-05-20 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167012148A Ceased KR20160056960A (ko) | 2008-04-16 | 2009-04-16 | α2,3- 및 α2,6-시알화를 포함하는 재조합 ＦＳＨ |
| KR1020177026920A Ceased KR20170110741A (ko) | 2008-04-16 | 2009-04-16 | α2,3- 및 α2,6-시알화를 포함하는 재조합 ＦＳＨ |
| KR1020107025581A Active KR101622944B1 (ko) | 2008-04-16 | 2009-04-16 | α2,3- 및 α2,6-시알화를 포함하는 재조합 ＦＳＨ |
| KR1020197022294A Expired - Fee Related KR102108377B1 (ko) | 2008-04-16 | 2009-04-16 | α2,3- 및 α2,6-시알화를 포함하는 재조합 ＦＳＨ |
| KR1020187023820A Ceased KR20180095140A (ko) | 2008-04-16 | 2009-04-16 | α2,3- 및 α2,6-시알화를 포함하는 재조합 ＦＳＨ |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020177026920A Ceased KR20170110741A (ko) | 2008-04-16 | 2009-04-16 | α2,3- 및 α2,6-시알화를 포함하는 재조합 ＦＳＨ |
| KR1020107025581A Active KR101622944B1 (ko) | 2008-04-16 | 2009-04-16 | α2,3- 및 α2,6-시알화를 포함하는 재조합 ＦＳＨ |
| KR1020197022294A Expired - Fee Related KR102108377B1 (ko) | 2008-04-16 | 2009-04-16 | α2,3- 및 α2,6-시알화를 포함하는 재조합 ＦＳＨ |
| KR1020187023820A Ceased KR20180095140A (ko) | 2008-04-16 | 2009-04-16 | α2,3- 및 α2,6-시알화를 포함하는 재조합 ＦＳＨ |
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| EP (7) | EP3045471B1 (https=) |
| JP (7) | JP2011519359A (https=) |
| KR (5) | KR20160056960A (https=) |
| CN (3) | CN105906703A (https=) |
| AR (1) | AR071479A1 (https=) |
| AU (5) | AU2009237479B2 (https=) |
| BR (1) | BRPI0910461B8 (https=) |
| CA (1) | CA2725257A1 (https=) |
| CY (1) | CY1115413T1 (https=) |
| DK (6) | DK2808340T3 (https=) |
| ES (5) | ES2468318T3 (https=) |
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| HU (9) | HUE068565T2 (https=) |
| IL (2) | IL208538A (https=) |
| LT (8) | LT2808340T (https=) |
| MX (3) | MX355457B (https=) |
| NO (4) | NO2017025I1 (https=) |
| NZ (1) | NZ588381A (https=) |
| PL (6) | PL3144318T3 (https=) |
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| RU (3) | RU2682270C2 (https=) |
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| SI (6) | SI2268666T1 (https=) |
| TW (1) | TWI488640B (https=) |
| WO (1) | WO2009127826A1 (https=) |
| ZA (1) | ZA201007373B (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
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| TWI488640B (zh) | 2008-04-16 | 2015-06-21 | 菲瑞茵國際中心股份有限公司 | 藥學製劑 |
| TWI532495B (zh) | 2009-10-05 | 2016-05-11 | 菲瑞茵國際中心股份有限公司 | 藥學製劑 |
| EP2417982A1 (en) | 2010-07-30 | 2012-02-15 | Ferring B.V. | Stabilization of gonadotropins |
| WO2012016576A1 (en) * | 2010-08-04 | 2012-02-09 | Glycotope Gmbh | Improved recombinant human follicle-stimulating hormone |
| PT2621517E (pt) | 2010-09-29 | 2015-10-16 | Ferring Bv | Composição para uso no tratamento da infertilidade |
| WO2012050175A1 (ja) | 2010-10-15 | 2012-04-19 | 日本ケミカルリサーチ株式会社 | 糖鎖の非還元末端がマンノース残基である糖蛋白質の製造方法 |
| PL2691119T3 (pl) | 2011-03-31 | 2019-01-31 | Ferring B.V. | Preparat farmaceutyczny |
| EP2717904A1 (en) | 2011-06-06 | 2014-04-16 | Ferring BV | Pharmaceutical preparation comprising recombinant fsh |
| JO3092B1 (ar) * | 2011-08-08 | 2017-03-15 | Ferring Bv | مركب لتحفيز مسيطر عليه للمبيض |
| WO2013093760A2 (en) * | 2011-12-19 | 2013-06-27 | Grifols, S.A. | Compositions, methods, and kits for preparing sialylated recombinant proteins |
| US9657310B2 (en) * | 2012-04-27 | 2017-05-23 | Jcr Pharmaceuticals Co., Ltd. | Expression vector |
| EP2824176A1 (en) | 2013-07-11 | 2015-01-14 | Siamed'xpress | Methods for producing sialylated therapeutic proteins |
| JP6652334B2 (ja) * | 2014-05-31 | 2020-02-19 | Ｊｃｒファーマ株式会社 | ウリジンとｎ−アセチル−ｄ−マンノサミンとを含有する培地 |
| WO2016102436A1 (en) * | 2014-12-22 | 2016-06-30 | F. Hoffmann-La Roche Ag | Cmp-dependent sialidase activity |
| EP3283097B1 (en) | 2015-04-17 | 2020-02-12 | Ferring B.V. | Fsh for treatment of infertility |
| MY179524A (en) | 2015-06-26 | 2020-11-10 | Ferring Bv | Methods of purification and/or viral inactivation |
| EP3205719A1 (en) * | 2016-02-15 | 2017-08-16 | CEVEC Pharmaceuticals GmbH | Cell lines for producing recombinant glycoproteins with di-antennary n-glycans, methods using the same, and recombinant glycoproteins |
| GB201603280D0 (en) | 2016-02-24 | 2016-04-13 | Ferring Bv | Stable liquid gonadotropin formulation |
| EP3382014A1 (en) * | 2017-03-29 | 2018-10-03 | CEVEC Pharmaceuticals GmbH | Recombinant glycoproteins with reduced antennary fucosylation |
| EP3441471A1 (en) | 2017-08-08 | 2019-02-13 | CEVEC Pharmaceuticals GmbH | Use of constitutively active variants of growth factor receptors as selection makers for the generation of stable producer cell lines |
| MX2020002235A (es) | 2017-09-01 | 2020-07-20 | Ferring Bv | Composicion para la estimulacion ovarica controlada. |
| HUE071268T2 (hu) | 2018-04-30 | 2025-08-28 | Ferring Bv | Készítmény szabályozott petefészek-stimuláláshoz |
| TWI846743B (zh) | 2018-10-17 | 2024-07-01 | 荷蘭商菲林公司 | 用於控制性卵巢刺激之組成物及方法 |
| US20220380785A1 (en) * | 2019-11-01 | 2022-12-01 | The University Of British Columbia | Compositions and methods for sialylated mucin-type o-glycosylation of therapeutic proteins |
| TW202237173A (zh) | 2020-12-09 | 2022-10-01 | 荷蘭商菲林公司 | 用於受控的卵巢刺激之組成物及方法 |
| KR20240167660A (ko) | 2022-04-01 | 2024-11-27 | 훼링 비.브이. | 불임의 치료를 위한 혼합 프로토콜 |
| AU2023275943A1 (en) | 2022-05-26 | 2024-10-17 | Ferring B.V. | Compositions and methods for treatment of infertility in males |
| KR20250033230A (ko) | 2022-07-08 | 2025-03-07 | 훼링 비.브이. | 자궁내 인공수정(iui)을 위한 조성물 및 방법 |
| AR133300A1 (es) | 2023-07-20 | 2025-09-17 | Ferring Bv | Micropartículas cargadas con fármaco de liberación prolongada |
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| IT1206302B (it) | 1987-06-26 | 1989-04-14 | Serono Cesare Ist Ricerca | Ormone follicolo-stimolante urinario |
| US5541083A (en) | 1989-10-24 | 1996-07-30 | The Regents Of The University Of California | Method for producing secretable glycosyltransferases and other golgi processing enzymes |
| IL160406A0 (en) | 1995-06-15 | 2004-07-25 | Crucell Holland Bv | A cell harbouring nucleic acid encoding adenoritus e1a and e1b gene products |
| JP3559652B2 (ja) * | 1996-06-25 | 2004-09-02 | グローリー工業株式会社 | 売上精算システムの管理装置 |
| IL122732A0 (en) * | 1997-01-15 | 1998-08-16 | Akzo Nobel Nv | Liquid gonadotropin-containing formulation its preparation and a device containing same |
| JP2001507215A (ja) | 1997-01-16 | 2001-06-05 | サイテル コーポレイション | 組換え糖タンパク質のインビトロでの実用的なシアリル化 |
| JPH1111665A (ja) | 1997-06-28 | 1999-01-19 | Shibuya Kogyo Co Ltd | 無菌エア搬送コンベヤ装置 |
| TWI235158B (en) * | 1997-09-01 | 2005-07-01 | Kirin Brewery | Human thrombopoietin produced by human established cell lines, processes foe preparing the same, and pharmaceutical composition comprising the same |
| PT1176976E (pt) | 1999-05-07 | 2006-11-30 | Applied Research Systems | Utilização de lh administrada na fase folicular média e tardia para o tratamento de mulheres anovulatórias. |
| JP2002011665A (ja) | 2000-06-28 | 2002-01-15 | Sintokogio Ltd | ショットブラスト装置モニタシステム |
| IL140110A0 (en) | 2000-12-05 | 2002-02-10 | Applied Research Systems | Improvement of homogeneity and secretion of recombinant proteins in mammalian systems |
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| ATE542904T1 (de) | 2001-10-29 | 2012-02-15 | Crucell Holland Bv | Verfahren und mittel zur herstellung von proteinen mit vorbestimmten posttranslationalen modifikationen |
| PT1465987E (pt) | 2001-12-07 | 2008-04-15 | Crucell Holland Bv | Produção de vírus, isolados virais e vacinas |
| US20040248784A1 (en) | 2003-06-03 | 2004-12-09 | Marco Filicori | Unitary combinations of FSH and hCG |
| JP2007515410A (ja) * | 2003-12-03 | 2007-06-14 | ネオス テクノロジーズ インコーポレイテッド | ＧｌｙｃｏＰＥＧ化卵胞刺激ホルモン |
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| TWI488640B (zh) | 2008-04-16 | 2015-06-21 | 菲瑞茵國際中心股份有限公司 | 藥學製劑 |
| TWI532495B (zh) | 2009-10-05 | 2016-05-11 | 菲瑞茵國際中心股份有限公司 | 藥學製劑 |
| EP2417982A1 (en) | 2010-07-30 | 2012-02-15 | Ferring B.V. | Stabilization of gonadotropins |
| US8790322B2 (en) | 2010-08-03 | 2014-07-29 | King Saud University | Stoma coat |
| WO2012016576A1 (en) * | 2010-08-04 | 2012-02-09 | Glycotope Gmbh | Improved recombinant human follicle-stimulating hormone |
| PT2621517E (pt) | 2010-09-29 | 2015-10-16 | Ferring Bv | Composição para uso no tratamento da infertilidade |
| PL2691119T3 (pl) | 2011-03-31 | 2019-01-31 | Ferring B.V. | Preparat farmaceutyczny |
| EP2717904A1 (en) | 2011-06-06 | 2014-04-16 | Ferring BV | Pharmaceutical preparation comprising recombinant fsh |
| JO3092B1 (ar) | 2011-08-08 | 2017-03-15 | Ferring Bv | مركب لتحفيز مسيطر عليه للمبيض |
| MX2016013449A (es) | 2014-04-18 | 2017-05-04 | Glycotope Gmbh | Hiperestimulacion ovarica controlada con la hormona estimuladora folicular humana recombinante mejorada. |
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2009
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2010
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