|
US4458066A
(en)
|
1980-02-29 |
1984-07-03 |
University Patents, Inc. |
Process for preparing polynucleotides
|
|
US4469863A
(en)
|
1980-11-12 |
1984-09-04 |
Ts O Paul O P |
Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof
|
|
US4362867A
(en)
|
1980-12-10 |
1982-12-07 |
Research Corporation |
Recombinant cDNA construction method and hybrid nucleotides useful in cloning
|
|
US5171534A
(en)
|
1984-01-16 |
1992-12-15 |
California Institute Of Technology |
Automated DNA sequencing technique
|
|
US4582877A
(en)
|
1984-07-27 |
1986-04-15 |
The Dow Chemical Company |
Transamidated poly-2-oxazoline compositions useful as wetting agents for polymer and absorbents for polar materials
|
|
US5242794A
(en)
|
1984-12-13 |
1993-09-07 |
Applied Biosystems, Inc. |
Detection of specific sequences in nucleic acids
|
|
US5034506A
(en)
|
1985-03-15 |
1991-07-23 |
Anti-Gene Development Group |
Uncharged morpholino-based polymers having achiral intersubunit linkages
|
|
US5235033A
(en)
|
1985-03-15 |
1993-08-10 |
Anti-Gene Development Group |
Alpha-morpholino ribonucleoside derivatives and polymers thereof
|
|
US4876187A
(en)
|
1985-12-05 |
1989-10-24 |
Meiogenics, Inc. |
Nucleic acid compositions with scissile linkage useful for detecting nucleic acid sequences
|
|
US5011769A
(en)
|
1985-12-05 |
1991-04-30 |
Meiogenics U.S. Limited Partnership |
Methods for detecting nucleic acid sequences
|
|
US4996143A
(en)
|
1985-12-23 |
1991-02-26 |
Syngene, Inc. |
Fluorescent stokes shift probes for polynucleotide hybridization
|
|
US5721098A
(en)
|
1986-01-16 |
1998-02-24 |
The Regents Of The University Of California |
Comparative genomic hybridization
|
|
US4935357A
(en)
|
1986-02-05 |
1990-06-19 |
New England Biolabs, Inc. |
Universal restriction endonuclease
|
|
US4925065A
(en)
|
1987-01-02 |
1990-05-15 |
Helena Laboratories Corporation |
Dispensing apparatus
|
|
US6270961B1
(en)
|
1987-04-01 |
2001-08-07 |
Hyseq, Inc. |
Methods and apparatus for DNA sequencing and DNA identification
|
|
US6090591A
(en)
|
1987-07-31 |
2000-07-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Selective amplification of target polynucleotide sequences
|
|
US4942124A
(en)
|
1987-08-11 |
1990-07-17 |
President And Fellows Of Harvard College |
Multiplex sequencing
|
|
US6004745A
(en)
|
1987-09-21 |
1999-12-21 |
Gen-Probe Incorporated |
Hybridization protection assay
|
|
JP2650159B2
(ja)
|
1988-02-24 |
1997-09-03 |
アクゾ・ノベル・エヌ・ベー |
核酸増幅方法
|
|
CA1340807C
(en)
|
1988-02-24 |
1999-11-02 |
Lawrence T. Malek |
Nucleic acid amplification process
|
|
US5082830A
(en)
|
1988-02-26 |
1992-01-21 |
Enzo Biochem, Inc. |
End labeled nucleotide probe
|
|
JP2856804B2
(ja)
|
1988-03-24 |
1999-02-10 |
ユニバーシティ オブ アイオワ リサーチ ファウンデイション |
標識された相補的核酸プローブを開裂する触媒反応の補因子としての活性に基づく核酸配列検出のための触媒ハイブリッド形成系
|
|
US4988617A
(en)
|
1988-03-25 |
1991-01-29 |
California Institute Of Technology |
Method of detecting a nucleotide change in nucleic acids
|
|
US5216141A
(en)
|
1988-06-06 |
1993-06-01 |
Benner Steven A |
Oligonucleotide analogs containing sulfur linkages
|
|
US6107023A
(en)
|
1988-06-17 |
2000-08-22 |
Genelabs Technologies, Inc. |
DNA amplification and subtraction techniques
|
|
US5130238A
(en)
|
1988-06-24 |
1992-07-14 |
Cangene Corporation |
Enhanced nucleic acid amplification process
|
|
US5681726A
(en)
|
1988-09-19 |
1997-10-28 |
Stratagene |
Method of double stranded DNA synthesis
|
|
EP0377229B1
(en)
|
1989-01-05 |
1996-06-26 |
Laboratorios Leti, S.A. |
Use of specific properties of allergens from animal sources and methods for their isolation
|
|
US5508178A
(en)
|
1989-01-19 |
1996-04-16 |
Rose; Samuel |
Nucleic acid amplification using single primer
|
|
US5708154A
(en)
|
1989-02-24 |
1998-01-13 |
City Of Hope |
RNA-DNA hybrid molecules of nucleic acid
|
|
US5234809A
(en)
|
1989-03-23 |
1993-08-10 |
Akzo N.V. |
Process for isolating nucleic acid
|
|
CA2013317A1
(en)
*
|
1989-04-17 |
1990-10-17 |
Fred T. Oakes |
Diagnostic kit, primer composition and their use for replication or detection of nucleic acids
|
|
US5043272A
(en)
|
1989-04-27 |
1991-08-27 |
Life Technologies, Incorporated |
Amplification of nucleic acid sequences using oligonucleotides of random sequence as primers
|
|
US5035996A
(en)
|
1989-06-01 |
1991-07-30 |
Life Technologies, Inc. |
Process for controlling contamination of nucleic acid amplification reactions
|
|
US5683896A
(en)
|
1989-06-01 |
1997-11-04 |
Life Technologies, Inc. |
Process for controlling contamination of nucleic acid amplification reactions
|
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
|
EP0731175A3
(en)
|
1989-07-11 |
2004-05-26 |
Gen-Probe Incorporated |
Oligonucleotide probes for HIV nucleic acid
|
|
CA2020958C
(en)
|
1989-07-11 |
2005-01-11 |
Daniel L. Kacian |
Nucleic acid sequence amplification methods
|
|
US5545522A
(en)
|
1989-09-22 |
1996-08-13 |
Van Gelder; Russell N. |
Process for amplifying a target polynucleotide sequence using a single primer-promoter complex
|
|
US5391785A
(en)
|
1990-01-16 |
1995-02-21 |
La Jolla Pharmaceutial Company |
Intermediates for providing functional groups on the 5' end of oligonucleotides
|
|
CA2037349C
(en)
|
1990-03-26 |
2008-06-17 |
James G. Wetmur |
Branch migration of nucleotides
|
|
CA2036946C
(en)
|
1990-04-06 |
2001-10-16 |
Kenneth V. Deugau |
Indexing linkers
|
|
HU218095B
(hu)
|
1990-05-01 |
2000-05-28 |
Amgen Inc. |
Eljárás átvitt szennyeződések csökkentésére, amplifikációs eljárásokban
|
|
US5494810A
(en)
|
1990-05-03 |
1996-02-27 |
Cornell Research Foundation, Inc. |
Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
|
|
US5667976A
(en)
|
1990-05-11 |
1997-09-16 |
Becton Dickinson And Company |
Solid supports for nucleic acid hybridization assays
|
|
US5194370A
(en)
|
1990-05-16 |
1993-03-16 |
Life Technologies, Inc. |
Promoter ligation activated transcription amplification of nucleic acid sequences
|
|
DK0540693T3
(da)
|
1990-07-24 |
1999-09-13 |
Hoffmann La Roche |
Reduktion af ikke-specifik amplifikation under in vitro-nukleinsyreamplifikation under anvendelse af modificerede nukleinsy
|
|
US5602240A
(en)
|
1990-07-27 |
1997-02-11 |
Ciba Geigy Ag. |
Backbone modified oligonucleotide analogs
|
|
US5386023A
(en)
|
1990-07-27 |
1995-01-31 |
Isis Pharmaceuticals |
Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
|
|
WO1992007951A1
(en)
|
1990-10-19 |
1992-05-14 |
Yoke Wah Kow |
Quantitation of aldehyde-containing lesions in nucleic acids
|
|
US5518900A
(en)
|
1993-01-15 |
1996-05-21 |
Molecular Tool, Inc. |
Method for generating single-stranded DNA molecules
|
|
US6004744A
(en)
|
1991-03-05 |
1999-12-21 |
Molecular Tool, Inc. |
Method for determining nucleotide identity through extension of immobilized primer
|
|
US5888819A
(en)
|
1991-03-05 |
1999-03-30 |
Molecular Tool, Inc. |
Method for determining nucleotide identity through primer extension
|
|
US5090591A
(en)
|
1991-03-18 |
1992-02-25 |
Longford Equipment International Limited |
Article dispenser for use with continuous strip of articles
|
|
US5169766A
(en)
|
1991-06-14 |
1992-12-08 |
Life Technologies, Inc. |
Amplification of nucleic acid molecules
|
|
US5644048A
(en)
|
1992-01-10 |
1997-07-01 |
Isis Pharmaceuticals, Inc. |
Process for preparing phosphorothioate oligonucleotides
|
|
EP0631635B1
(en)
|
1992-03-04 |
2001-09-12 |
The Regents Of The University Of California |
Comparative genomic hybridization (cgh)
|
|
US5965362A
(en)
|
1992-03-04 |
1999-10-12 |
The Regents Of The University Of California |
Comparative genomic hybridization (CGH)
|
|
ATE212998T1
(de)
|
1992-03-05 |
2002-02-15 |
Isis Pharmaceuticals Inc |
Kovalent vernetzte oligonukleotide
|
|
ATE231920T1
(de)
|
1992-03-11 |
2003-02-15 |
Dana Farber Cancer Inst Inc |
Methode um mrna zu klonieren
|
|
AU681082B2
(en)
|
1992-05-06 |
1997-08-21 |
Gen-Probe Incorporated |
Nucleic acid sequence amplification method, composition and kit
|
|
US5710028A
(en)
|
1992-07-02 |
1998-01-20 |
Eyal; Nurit |
Method of quick screening and identification of specific DNA sequences by single nucleotide primer extension and kits therefor
|
|
US6172208B1
(en)
|
1992-07-06 |
2001-01-09 |
Genzyme Corporation |
Oligonucleotides modified with conjugate groups
|
|
WO1994003637A1
(en)
|
1992-07-31 |
1994-02-17 |
Syntex (Usa) Inc. |
Method for introducing defined sequences at the 3' end of polynucleotides
|
|
US6180338B1
(en)
*
|
1992-08-04 |
2001-01-30 |
Beckman Coulter, Inc. |
Method, reagent and kit for the detection and amplification of nucleic acid sequences
|
|
US5422271A
(en)
|
1992-11-20 |
1995-06-06 |
Eastman Kodak Company |
Nucleic acid material amplification and detection without washing
|
|
US5445935A
(en)
|
1992-11-23 |
1995-08-29 |
Royer; Catherine A. |
Quantitative detection of macromolecules with fluorescent oligonucleotides
|
|
US5591575A
(en)
|
1993-04-07 |
1997-01-07 |
Amersham International Plc |
Subtraction hybridization employing aziridinylbenoquinone cross-linking agents
|
|
US5837832A
(en)
|
1993-06-25 |
1998-11-17 |
Affymetrix, Inc. |
Arrays of nucleic acid probes on biological chips
|
|
US6027923A
(en)
|
1993-07-23 |
2000-02-22 |
Bio-Rad Laboratories, Inc. |
Linked linear amplification of nucleic acids
|
|
DE4344726C2
(de)
|
1993-12-27 |
1997-09-25 |
Deutsches Krebsforsch |
Verfahren zum Nachweis von nicht balanciertem genetischen Material einer Spezies oder zum Nachweis der Genexpression in Zellen einer Spezies
|
|
CA2140081C
(en)
|
1994-01-13 |
2008-04-01 |
Dean L. Engelhardt |
Process, construct and conjugate for producing multiple nucleic acid copies
|
|
US5654419A
(en)
|
1994-02-01 |
1997-08-05 |
The Regents Of The University Of California |
Fluorescent labels and their use in separations
|
|
US5578832A
(en)
|
1994-09-02 |
1996-11-26 |
Affymetrix, Inc. |
Method and apparatus for imaging a sample on a device
|
|
US5637684A
(en)
|
1994-02-23 |
1997-06-10 |
Isis Pharmaceuticals, Inc. |
Phosphoramidate and phosphorothioamidate oligomeric compounds
|
|
DE4406524A1
(de)
|
1994-02-28 |
1995-08-31 |
Boehringer Mannheim Gmbh |
3'-RNA-Markierung mit Terminaler Transferase
|
|
US6110709A
(en)
|
1994-03-18 |
2000-08-29 |
The General Hospital Corporation |
Cleaved amplified modified polymorphic sequence detection methods
|
|
US5641658A
(en)
|
1994-08-03 |
1997-06-24 |
Mosaic Technologies, Inc. |
Method for performing amplification of nucleic acid with two primers bound to a single solid support
|
|
US5705628A
(en)
|
1994-09-20 |
1998-01-06 |
Whitehead Institute For Biomedical Research |
DNA purification and isolation using magnetic particles
|
|
US5525471A
(en)
|
1994-10-12 |
1996-06-11 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Enzymatic degrading subtraction hybridization
|
|
US6280935B1
(en)
|
1994-10-13 |
2001-08-28 |
Lynx Therapeutics, Inc. |
Method of detecting the presence or absence of a plurality of target sequences using oligonucleotide tags
|
|
US5556752A
(en)
|
1994-10-24 |
1996-09-17 |
Affymetrix, Inc. |
Surface-bound, unimolecular, double-stranded DNA
|
|
US6309843B1
(en)
|
1994-10-25 |
2001-10-30 |
The Curators Of The University Of Missouri |
Glycoprotein for use in determining endometrial receptivity
|
|
US6194211B1
(en)
|
1994-11-18 |
2001-02-27 |
Glaxo Wellcome Inc. |
Transcriptional regulatory sequence of carcinoembryonic antigen for expression targeting
|
|
US5565340A
(en)
|
1995-01-27 |
1996-10-15 |
Clontech Laboratories, Inc. |
Method for suppressing DNA fragment amplification during PCR
|
|
US5750341A
(en)
|
1995-04-17 |
1998-05-12 |
Lynx Therapeutics, Inc. |
DNA sequencing by parallel oligonucleotide extensions
|
|
US5763178A
(en)
|
1995-06-07 |
1998-06-09 |
Trevigen, Inc. |
Oscillating signal amplifier for nucleic acid detection
|
|
US5882867A
(en)
|
1995-06-07 |
1999-03-16 |
Dade Behring Marburg Gmbh |
Detection of nucleic acids by formation of template-dependent product
|
|
EP0832294A1
(en)
|
1995-06-07 |
1998-04-01 |
Pioneer Hi-Bred International, Inc. |
PCR-BASED cDNA SUBTRACTIVE CLONING METHOD
|
|
US5789206A
(en)
|
1995-07-07 |
1998-08-04 |
Myriad Genetics, Inc. |
Method for ligating adaptors to nucleic acids which methods are useful for obtaining the ends of genes
|
|
NZ298494A
(en)
|
1995-07-11 |
1999-09-29 |
Forfas Trading As Bioresearch |
Glycosylase mediated detection of nucleotide sequences at candidate loci
|
|
FR2737223B1
(fr)
|
1995-07-24 |
1997-09-12 |
Bio Merieux |
Procede d'amplification de sequences d'acide nucleique par deplacement, a l'aide d'amorces chimeres
|
|
US5712126A
(en)
|
1995-08-01 |
1998-01-27 |
Yale University |
Analysis of gene expression by display of 3-end restriction fragments of CDNA
|
|
US6068829A
(en)
|
1995-09-11 |
2000-05-30 |
The Burnham Institute |
Method of identifying molecules that home to a selected organ in vivo
|
|
US6190865B1
(en)
|
1995-09-27 |
2001-02-20 |
Epicentre Technologies Corporation |
Method for characterizing nucleic acid molecules
|
|
GB9600384D0
(en)
|
1996-01-09 |
1996-03-13 |
Nyfotek As |
Dna glycosylases
|
|
US6825011B1
(en)
|
1998-12-17 |
2004-11-30 |
Yuri Rumantichikov |
Methods for insertion of nucleic acids into circular vectors
|
|
JP4468488B2
(ja)
|
1996-05-29 |
2010-05-26 |
コーネル・リサーチ・ファンデーション・インコーポレイテッド |
組み合せたリガーゼ検出およびポリメラーゼ連鎖反応を用いる核酸配列相違の検出
|
|
EP2264045B1
(en)
|
1996-08-14 |
2015-10-21 |
Life Technologies Corporation |
Stable compositions for nucleic acid amplification and sequencing
|
|
GB9620209D0
(en)
|
1996-09-27 |
1996-11-13 |
Cemu Bioteknik Ab |
Method of sequencing DNA
|
|
US6449562B1
(en)
|
1996-10-10 |
2002-09-10 |
Luminex Corporation |
Multiplexed analysis of clinical specimens apparatus and method
|
|
US6258533B1
(en)
|
1996-11-01 |
2001-07-10 |
The University Of Iowa Research Foundation |
Iterative and regenerative DNA sequencing method
|
|
IL120337A0
(en)
|
1997-02-27 |
1997-06-10 |
Gesher Israel Advanced Biotecs |
Method for joining DNA fragments
|
|
US6197557B1
(en)
|
1997-03-05 |
2001-03-06 |
The Regents Of The University Of Michigan |
Compositions and methods for analysis of nucleic acids
|
|
US6770748B2
(en)
|
1997-03-07 |
2004-08-03 |
Takeshi Imanishi |
Bicyclonucleoside and oligonucleotide analogue
|
|
EP2327797B1
(en)
|
1997-04-01 |
2015-11-25 |
Illumina Cambridge Limited |
Method of nucleic acid sequencing
|
|
AU731069B2
(en)
|
1997-08-28 |
2001-03-22 |
Applied Biosystems, Llc |
Improved detection of mutations in nucleic acids by chemical cleavage
|
|
AU9660698A
(en)
|
1997-08-29 |
1999-03-16 |
Osvaldo J. Lopez |
Dna methyltransferase genotyping
|
|
US6794499B2
(en)
|
1997-09-12 |
2004-09-21 |
Exiqon A/S |
Oligonucleotide analogues
|
|
US6169194B1
(en)
|
1997-10-16 |
2001-01-02 |
Michael Thompson |
High surface density covalent immobilization of oligonucleotide monolayers using a 1-(thiotrifluoroacetato)-11-(trichlorososilyl)-undecane linker
|
|
PT1040202E
(pt)
|
1997-10-28 |
2009-03-26 |
Los Alamos Nat Security Llc |
Determinação da identidade de polimorfismos de adn utilizando citometria de fluxo
|
|
US6090553A
(en)
|
1997-10-29 |
2000-07-18 |
Beckman Coulter, Inc. |
Use of uracil-DNA glycosylase in genetic analysis
|
|
US20010000077A1
(en)
|
1998-02-03 |
2001-03-29 |
Engelhardt Dean L. |
Novel process, construct and conjugate for producing multiple nucleic acid copies
|
|
US6365346B1
(en)
|
1998-02-18 |
2002-04-02 |
Dade Behring Inc. |
Quantitative determination of nucleic acid amplification products
|
|
US6174680B1
(en)
|
1998-12-30 |
2001-01-16 |
Dana-Farber Cancer Institute, Inc. |
Method for identifying mismatch repair glycosylase reactive sites, compounds and uses thereof
|
|
US6087103A
(en)
|
1998-03-04 |
2000-07-11 |
Lifespan Biosciences, Inc. |
Tagged ligand arrays for identifying target-ligand interactions
|
|
US6225451B1
(en)
|
1998-04-06 |
2001-05-01 |
Myriad Genetics, Inc. |
Chromosome 11-linked coronary heart disease susceptibility gene CHD1
|
|
ES2172887T3
(es)
|
1998-04-22 |
2002-10-01 |
Entpr Ie Trd As Bioresearch Ie |
Un metodo para caracterizar moleculas de acido nucleico que implica generar fragmentos de dna aguas arriba y extensibles que resultan de la escision de un acido nucleico en un sitio abasico.
|
|
US7875440B2
(en)
|
1998-05-01 |
2011-01-25 |
Arizona Board Of Regents |
Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
|
|
GB0002310D0
(en)
|
2000-02-01 |
2000-03-22 |
Solexa Ltd |
Polynucleotide sequencing
|
|
US20030022207A1
(en)
|
1998-10-16 |
2003-01-30 |
Solexa, Ltd. |
Arrayed polynucleotides and their use in genome analysis
|
|
US6787308B2
(en)
|
1998-07-30 |
2004-09-07 |
Solexa Ltd. |
Arrayed biomolecules and their use in sequencing
|
|
GB9817055D0
(en)
|
1998-08-05 |
1998-09-30 |
Medical Res Council |
Reverse transcription and amplification processes and primers therefore
|
|
US6232067B1
(en)
|
1998-08-17 |
2001-05-15 |
The Perkin-Elmer Corporation |
Adapter directed expression analysis
|
|
US6160105A
(en)
|
1998-10-13 |
2000-12-12 |
Incyte Pharmaceuticals, Inc. |
Monitoring toxicological responses
|
|
US6150112A
(en)
|
1998-09-18 |
2000-11-21 |
Yale University |
Methods for identifying DNA sequences for use in comparison of DNA samples by their lack of polymorphism using Y shape adaptors
|
|
US6287825B1
(en)
|
1998-09-18 |
2001-09-11 |
Molecular Staging Inc. |
Methods for reducing the complexity of DNA sequences
|
|
AR021833A1
(es)
|
1998-09-30 |
2002-08-07 |
Applied Research Systems |
Metodos de amplificacion y secuenciacion de acido nucleico
|
|
US6440705B1
(en)
|
1998-10-01 |
2002-08-27 |
Vincent P. Stanton, Jr. |
Method for analyzing polynucleotides
|
|
WO2000039345A1
(en)
|
1998-12-30 |
2000-07-06 |
Dana-Farber Cancer Institute, Inc. |
Mutation scanning array, and methods of use thereof
|
|
EP2145963A1
(en)
|
1999-01-06 |
2010-01-20 |
Callida Genomics, Inc. |
Enhanced sequencing by hybridization using pools of probes
|
|
US7074556B2
(en)
|
1999-03-02 |
2006-07-11 |
Invitrogen Corporation |
cDNA synthesis improvements
|
|
EP1173609A2
(en)
|
1999-03-12 |
2002-01-23 |
Amersham Pharmacia Biotech UK Limited |
Genetic analysis
|
|
AU4739600A
(en)
|
1999-05-17 |
2000-12-05 |
Mcgill University |
Method for subtracting cdnas by suppressing the synthesis of specifically targeted mrnas
|
|
US7056661B2
(en)
|
1999-05-19 |
2006-06-06 |
Cornell Research Foundation, Inc. |
Method for sequencing nucleic acid molecules
|
|
US6225109B1
(en)
|
1999-05-27 |
2001-05-01 |
Orchid Biosciences, Inc. |
Genetic analysis device
|
|
US6056661A
(en)
|
1999-06-14 |
2000-05-02 |
General Motors Corporation |
Multi-range transmission with input split planetary gear set and continuously variable transmission unit
|
|
US7501245B2
(en)
|
1999-06-28 |
2009-03-10 |
Helicos Biosciences Corp. |
Methods and apparatuses for analyzing polynucleotide sequences
|
|
US6339147B1
(en)
|
1999-07-29 |
2002-01-15 |
Epoch Biosciences, Inc. |
Attachment of oligonucleotides to solid supports through Schiff base type linkages for capture and detection of nucleic acids
|
|
US6232104B1
(en)
|
1999-08-17 |
2001-05-15 |
Dade Behring Inc. |
Detection of differences in nucleic acids by inhibition of spontaneous DNA branch migration
|
|
US6251639B1
(en)
|
1999-09-13 |
2001-06-26 |
Nugen Technologies, Inc. |
Methods and compositions for linear isothermal amplification of polynucleotide sequences, using a RNA-DNA composite primer
|
|
US6692918B2
(en)
|
1999-09-13 |
2004-02-17 |
Nugen Technologies, Inc. |
Methods and compositions for linear isothermal amplification of polynucleotide sequences
|
|
US6262490B1
(en)
|
1999-11-05 |
2001-07-17 |
Advanced Semiconductor Engineering, Inc. |
Substrate strip for use in packaging semiconductor chips
|
|
US7244559B2
(en)
|
1999-09-16 |
2007-07-17 |
454 Life Sciences Corporation |
Method of sequencing a nucleic acid
|
|
US7211390B2
(en)
|
1999-09-16 |
2007-05-01 |
454 Life Sciences Corporation |
Method of sequencing a nucleic acid
|
|
EP1218543A2
(en)
|
1999-09-29 |
2002-07-03 |
Solexa Ltd. |
Polynucleotide sequencing
|
|
US6617442B1
(en)
|
1999-09-30 |
2003-09-09 |
Isis Pharmaceuticals, Inc. |
Human Rnase H1 and oligonucleotide compositions thereof
|
|
US6958225B2
(en)
|
1999-10-27 |
2005-10-25 |
Affymetrix, Inc. |
Complexity management of genomic DNA
|
|
US6077674A
(en)
|
1999-10-27 |
2000-06-20 |
Agilent Technologies Inc. |
Method of producing oligonucleotide arrays with features of high purity
|
|
US6582938B1
(en)
|
2001-05-11 |
2003-06-24 |
Affymetrix, Inc. |
Amplification of nucleic acids
|
|
US20010031739A1
(en)
|
1999-12-21 |
2001-10-18 |
Dare Akintade Oyedele |
Method and kit for quantitating genomic DNA damage and repair capicity
|
|
AU2170901A
(en)
|
1999-12-21 |
2001-07-03 |
Lion Bioscience Ag |
Branched compound for use in nucleic acid detection and analysis reactions
|
|
US6913884B2
(en)
|
2001-08-16 |
2005-07-05 |
Illumina, Inc. |
Compositions and methods for repetitive use of genomic DNA
|
|
US7205129B1
(en)
|
2000-02-28 |
2007-04-17 |
Qiagen Gmbh |
Method for reducing artifacts in nucleic acid amplification
|
|
JP5148799B2
(ja)
|
2000-03-15 |
2013-02-20 |
ライフ テクノロジーズ コーポレーション |
高忠実度逆転写酵素およびその使用
|
|
US6917726B2
(en)
|
2001-09-27 |
2005-07-12 |
Cornell Research Foundation, Inc. |
Zero-mode clad waveguides for performing spectroscopy with confined effective observation volumes
|
|
US6936702B2
(en)
|
2000-06-07 |
2005-08-30 |
Li-Cor, Inc. |
Charge-switch nucleotides
|
|
JP2004513617A
(ja)
|
2000-06-26 |
2004-05-13 |
ニューゲン テクノロジーズ， インコーポレイテッド |
転写に基づく核酸増幅のための方法および組成物
|
|
US7846733B2
(en)
|
2000-06-26 |
2010-12-07 |
Nugen Technologies, Inc. |
Methods and compositions for transcription-based nucleic acid amplification
|
|
US20020164634A1
(en)
|
2000-08-26 |
2002-11-07 |
Perlegen Sciences, Inc. |
Methods for reducing complexity of nucleic acid samples
|
|
JP3353149B2
(ja)
|
2000-08-28 |
2002-12-03 |
ホーコス株式会社 |
工作機械の主軸装置
|
|
WO2002028876A2
(en)
|
2000-10-05 |
2002-04-11 |
Riken |
Oligonucleotide linkers comprising a variable cohesive portion and method for the preparation of polynucleotide libraries by using said linkers.
|
|
JP2004537257A
(ja)
|
2000-10-06 |
2004-12-16 |
ニューゲン テクノロジーズ， インコーポレイテッド |
核酸配列の検出および／または定量のための、方法およびプローブ
|
|
US6924104B2
(en)
|
2000-10-27 |
2005-08-02 |
Yale University |
Methods for identifying genes associated with diseases or specific phenotypes
|
|
IE20000887A1
(en)
|
2000-11-03 |
2002-12-11 |
Univ College Cork Nat Univ Ie |
Method for the amplification and optional characterisation of nucleic acids
|
|
US6777180B1
(en)
|
2000-11-28 |
2004-08-17 |
Trustees Of Columbia University In The City Of New York |
Method for full-length cDNA cloning using degenerate stem-loop annealing primers
|
|
US7001724B1
(en)
|
2000-11-28 |
2006-02-21 |
Applera Corporation |
Compositions, methods, and kits for isolating nucleic acids using surfactants and proteases
|
|
AU2002228974A1
(en)
|
2000-12-13 |
2002-06-24 |
Nugen Technologies, Inc |
Methods and compositions for generation of multiple copies of nucleic acid sequences and methods of detection thereof
|
|
US6893820B1
(en)
|
2001-01-31 |
2005-05-17 |
The Ohio State University Research Foundation |
Detection of methylated CpG rich sequences diagnostic for malignant cells
|
|
CA2439074A1
(en)
|
2001-03-09 |
2002-09-19 |
Nugen Technologies, Inc. |
Methods and compositions for amplification of rna sequences
|
|
US6946251B2
(en)
|
2001-03-09 |
2005-09-20 |
Nugen Technologies, Inc. |
Methods and compositions for amplification of RNA sequences using RNA-DNA composite primers
|
|
WO2002081753A1
(en)
|
2001-04-04 |
2002-10-17 |
Advanced Research & Technology Institute |
Method for identifying and characterizing individual dna molecules
|
|
US7060441B2
(en)
|
2001-05-04 |
2006-06-13 |
Biomerieux |
Method for fragmenting and labeling DNA involving abasic sites and phosphate labeling
|
|
FR2824335A1
(fr)
|
2001-05-04 |
2002-11-08 |
Bio Merieux |
Procede de marquage et de fragmentation d'adn
|
|
US6849404B2
(en)
|
2001-05-07 |
2005-02-01 |
Bioneer Corporation |
Polymerase chain reaction of DNA of which base sequence is completely unidentified
|
|
JP2004536596A
(ja)
|
2001-06-08 |
2004-12-09 |
ユー．エス． ジェノミクス， インコーポレイテッド |
メチル化状態に基づいて核酸を分析するための方法および生成物
|
|
GB0114853D0
(en)
|
2001-06-18 |
2001-08-08 |
Medical Res Council |
Happier Mapping
|
|
WO2003002736A2
(en)
|
2001-06-27 |
2003-01-09 |
Roche Diagnostics Gmbh |
A walk-through technique for in vitro recombination of polynucleotide sequences
|
|
US20050009022A1
(en)
|
2001-07-06 |
2005-01-13 |
Weiner Michael P. |
Method for isolation of independent, parallel chemical micro-reactions using a porous filter
|
|
EP1275735A1
(en)
|
2001-07-11 |
2003-01-15 |
Roche Diagnostics GmbH |
Composition and method for hot start nucleic acid amplification
|
|
US6632611B2
(en)
|
2001-07-20 |
2003-10-14 |
Affymetrix, Inc. |
Method of target enrichment and amplification
|
|
JP2006500901A
(ja)
|
2001-09-26 |
2006-01-12 |
エピジェンクス ファーマスーティカルズ、 インコーポレイテッド |
Ｄｎａメチル化変化のアッセイ
|
|
US20040002371A1
(en)
|
2001-10-01 |
2004-01-01 |
Claude Paquin |
Method and apparatus for automated system for validating a set of collectible lottery tickets
|
|
JP2004148509A
(ja)
|
2001-10-04 |
2004-05-27 |
Seiko Epson Corp |
液体噴射ヘッド
|
|
US6977148B2
(en)
|
2001-10-15 |
2005-12-20 |
Qiagen Gmbh |
Multiple displacement amplification
|
|
US7176025B2
(en)
|
2002-03-11 |
2007-02-13 |
Nugen Technologies, Inc. |
Methods for generating double stranded DNA comprising a 3′ single stranded portion and uses of these complexes for recombination
|
|
DE60310697D1
(de)
|
2002-03-15 |
2007-02-08 |
Epigenomics Ag |
Entdeckungs- und diagnoseverfahren mit 5-methylcytosin-dna-glycosylase
|
|
CA2480525A1
(en)
|
2002-03-29 |
2003-10-09 |
Nugen Technologies, Inc. |
Single primer isothermal nucleic acid amplification-enhanced analyte detection and quantification
|
|
US20040137456A1
(en)
|
2002-04-04 |
2004-07-15 |
Hiroki Yokota |
Method for identifying and characterizing individual dna molecules
|
|
US6815167B2
(en)
|
2002-04-25 |
2004-11-09 |
Geneohm Sciences |
Amplification of DNA to produce single-stranded product of defined sequence and length
|
|
US6887709B2
(en)
|
2002-05-09 |
2005-05-03 |
Lifescan, Inc. |
Devices, systems and methods for the containment and use of liquid solutions
|
|
EP1573056A4
(en)
|
2002-05-17 |
2007-11-28 |
Nugen Technologies Inc |
METHODS FOR FRAGMENTATION, LABELING AND IMMOBILIZATION OF NUCLEIC ACIDS
|
|
WO2003100019A2
(en)
|
2002-05-24 |
2003-12-04 |
Invitrogen Corporation |
Nested pcr employing degradable primers
|
|
WO2003102216A2
(en)
|
2002-05-31 |
2003-12-11 |
Diversa Corporation |
Multiplexed systems for nucleic acid sequencing
|
|
US7108976B2
(en)
|
2002-06-17 |
2006-09-19 |
Affymetrix, Inc. |
Complexity management of genomic DNA by locus specific amplification
|
|
AU2003254162A1
(en)
|
2002-07-24 |
2004-02-09 |
Immusol Incorporated |
Single promoter system for making sirna expression cassettes and expression libraries using a polymerase primer hairpin linker
|
|
EP1546345B1
(en)
|
2002-09-05 |
2007-03-28 |
Plant Bioscience Limited |
Genome partitioning
|
|
US7459273B2
(en)
|
2002-10-04 |
2008-12-02 |
Affymetrix, Inc. |
Methods for genotyping selected polymorphism
|
|
US7704687B2
(en)
|
2002-11-15 |
2010-04-27 |
The Johns Hopkins University |
Digital karyotyping
|
|
US7414117B2
(en)
|
2002-12-26 |
2008-08-19 |
Ngk Insulators, Ltd. |
Nucleotide derivative and DNA microarray
|
|
AU2004209001B2
(en)
|
2003-01-29 |
2007-10-11 |
454 Life Sciences Corporation |
Bead emulsion nucleic acid amplification
|
|
US7189512B2
(en)
|
2003-02-20 |
2007-03-13 |
Noga Porat |
Methods for variation detection
|
|
US20090124514A1
(en)
|
2003-02-26 |
2009-05-14 |
Perlegen Sciences, Inc. |
Selection probe amplification
|
|
US7745116B2
(en)
|
2003-04-08 |
2010-06-29 |
Pacific Biosciences Of California, Inc. |
Composition and method for nucleic acid sequencing
|
|
WO2004092418A2
(en)
|
2003-04-14 |
2004-10-28 |
Nugen Technologies, Inc. |
Global amplification using a randomly primed composite primer
|
|
US7300755B1
(en)
|
2003-05-12 |
2007-11-27 |
Fred Hutchinson Cancer Research Center |
Methods for haplotyping genomic DNA
|
|
WO2005038427A2
(en)
|
2003-06-05 |
2005-04-28 |
Medical Gene Center Ltd. |
Rapid identification of viruses of the upper respiratory tract infection including sars causing coronus viruses
|
|
CA2528577C
(en)
|
2003-06-20 |
2012-08-07 |
Illumina, Inc. |
Methods and compositions for whole genome amplification and genotyping
|
|
US20050123956A1
(en)
|
2003-09-25 |
2005-06-09 |
Affymetrix, Inc. |
Methods for modifying DNA for microarray analysis
|
|
US7169560B2
(en)
|
2003-11-12 |
2007-01-30 |
Helicos Biosciences Corporation |
Short cycle methods for sequencing polynucleotides
|
|
US20050136417A1
(en)
|
2003-12-19 |
2005-06-23 |
Affymetrix, Inc. |
Amplification of nucleic acids
|
|
WO2005065321A2
(en)
|
2003-12-29 |
2005-07-21 |
Nugen Technologies, Inc. |
Methods for analysis of nucleic acid methylation status and methods for fragmentation, labeling and immobilization of nucleic acids
|
|
US20050191682A1
(en)
|
2004-02-17 |
2005-09-01 |
Affymetrix, Inc. |
Methods for fragmenting DNA
|
|
US7595179B2
(en)
|
2004-04-19 |
2009-09-29 |
Applied Biosystems, Llc |
Recombinant reverse transcriptases
|
|
US7462452B2
(en)
|
2004-04-30 |
2008-12-09 |
Pacific Biosciences Of California, Inc. |
Field-switch sequencing
|
|
US7622281B2
(en)
|
2004-05-20 |
2009-11-24 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for clonal amplification of nucleic acid
|
|
US20060051789A1
(en)
|
2004-07-01 |
2006-03-09 |
Somagenics, Inc. |
Methods of preparation of gene-specific oligonucleotide libraries and uses thereof
|
|
US7361468B2
(en)
|
2004-07-02 |
2008-04-22 |
Affymetrix, Inc. |
Methods for genotyping polymorphisms in humans
|
|
US20060024711A1
(en)
|
2004-07-02 |
2006-02-02 |
Helicos Biosciences Corporation |
Methods for nucleic acid amplification and sequence determination
|
|
US7276720B2
(en)
|
2004-07-19 |
2007-10-02 |
Helicos Biosciences Corporation |
Apparatus and methods for analyzing samples
|
|
US20060024678A1
(en)
|
2004-07-28 |
2006-02-02 |
Helicos Biosciences Corporation |
Use of single-stranded nucleic acid binding proteins in sequencing
|
|
US20060216724A1
(en)
|
2004-07-30 |
2006-09-28 |
Affymetrix, Inc. |
Methods for normalized amplification of nucleic acids
|
|
US7867703B2
(en)
|
2004-08-26 |
2011-01-11 |
Agilent Technologies, Inc. |
Element defined sequence complexity reduction
|
|
US7170050B2
(en)
|
2004-09-17 |
2007-01-30 |
Pacific Biosciences Of California, Inc. |
Apparatus and methods for optical analysis of molecules
|
|
EP1790202A4
(en)
|
2004-09-17 |
2013-02-20 |
Pacific Biosciences California |
APPARATUS AND METHOD FOR ANALYZING MOLECULES
|
|
GB0422551D0
(en)
|
2004-10-11 |
2004-11-10 |
Univ Liverpool |
Labelling and sequencing of nucleic acids
|
|
CA2588122A1
(en)
|
2004-11-16 |
2006-05-26 |
Helicos Biosciences Corporation |
Tirf single molecule analysis and method of sequencing nucleic acids
|
|
CN100413978C
(zh)
*
|
2004-12-16 |
2008-08-27 |
上海交通大学 |
基于dna切割过程的双链dna序列测定的方法
|
|
EP1841879A4
(en)
|
2005-01-25 |
2009-05-27 |
Population Genetics Technologi |
ISOTHERMAL DNA AMPLIFICATION
|
|
US7462468B1
(en)
|
2005-01-28 |
2008-12-09 |
Pacific Biosciences Of California, Inc. |
DNA intercalating agents and methods of use
|
|
CA2593855A1
(en)
|
2005-01-31 |
2006-08-10 |
Pacific Biosciences Of California, Inc. |
Use of reversible extension terminator in nucleic acid sequencing
|
|
US20060286566A1
(en)
|
2005-02-03 |
2006-12-21 |
Helicos Biosciences Corporation |
Detecting apparent mutations in nucleic acid sequences
|
|
US20060240451A1
(en)
|
2005-02-09 |
2006-10-26 |
Epicentre Technologies |
Compositions and methods employing 5' phosphate-dependent nucleic acid exonucleases
|
|
US7452671B2
(en)
|
2005-04-29 |
2008-11-18 |
Affymetrix, Inc. |
Methods for genotyping with selective adaptor ligation
|
|
US20060263789A1
(en)
|
2005-05-19 |
2006-11-23 |
Robert Kincaid |
Unique identifiers for indicating properties associated with entities to which they are attached, and methods for using
|
|
DE602006018744D1
(de)
|
2005-06-23 |
2011-01-20 |
Keygene Nv |
Strategien mit hohem durchsatz zur identifizierung und zum nachweis von polymorphismen
|
|
GB0514910D0
(en)
|
2005-07-20 |
2005-08-24 |
Solexa Ltd |
Method for sequencing a polynucleotide template
|
|
GB0514909D0
(en)
|
2005-07-20 |
2005-08-24 |
Solexa Ltd |
Methods of nucleic acid amplification and sequencing
|
|
US20070031857A1
(en)
|
2005-08-02 |
2007-02-08 |
Rubicon Genomics, Inc. |
Compositions and methods for processing and amplification of DNA, including using multiple enzymes in a single reaction
|
|
WO2007019444A2
(en)
|
2005-08-05 |
2007-02-15 |
Euclid Diagnostics Llc |
Subtractive separation and amplification of non-ribosomal transcribed rna (nrrna)
|
|
EP1929046B1
(en)
|
2005-09-07 |
2012-07-11 |
Nugen Technologies, Inc. |
Improved nucleic acid amplification procedure
|
|
US20090170713A1
(en)
|
2005-09-29 |
2009-07-02 |
Keygene N.V. |
High throughput screening of mutagenized populations
|
|
US7405281B2
(en)
|
2005-09-29 |
2008-07-29 |
Pacific Biosciences Of California, Inc. |
Fluorescent nucleotide analogs and uses therefor
|
|
WO2007053358A2
(en)
|
2005-10-28 |
2007-05-10 |
Praecis Pharmaceuticals, Inc. |
Methods for identifying compounds of interest using encoded libraries
|
|
GB0522310D0
(en)
|
2005-11-01 |
2005-12-07 |
Solexa Ltd |
Methods of preparing libraries of template polynucleotides
|
|
WO2007057652A1
(en)
|
2005-11-15 |
2007-05-24 |
Solexa Limited |
Method of target enrichment
|
|
CA2631248C
(en)
|
2005-11-28 |
2016-01-12 |
Pacific Biosciences Of California, Inc. |
Uniform surfaces for hybrid material substrates and methods for making and using same
|
|
ES2558124T3
(es)
|
2005-12-22 |
2016-02-02 |
Keygene N.V. |
Procedimiento para detección de polimorfismos basada en AFLP de alto rendimiento
|
|
EP1994179A2
(en)
|
2006-02-18 |
2008-11-26 |
Michael Strathmann |
Massively multiplexed sequencing
|
|
US20080038727A1
(en)
|
2006-03-10 |
2008-02-14 |
Applera Corporation |
MicroRNA and Messenger RNA Detection on Arrays
|
|
WO2007111937A1
(en)
|
2006-03-23 |
2007-10-04 |
Applera Corporation |
Directed enrichment of genomic dna for high-throughput sequencing
|
|
KR101087809B1
(ko)
|
2006-04-10 |
2011-11-29 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
단일 세포 및 콜로니의 수집을 위한 시스템
|
|
WO2008115185A2
(en)
|
2006-04-24 |
2008-09-25 |
Nimblegen Systems, Inc. |
Use of microarrays for genomic representation selection
|
|
US20080269476A1
(en)
|
2006-04-26 |
2008-10-30 |
Helicos Biosciences Corporation |
Molecules and methods for nucleic acid sequencing
|
|
US20090275486A1
(en)
|
2006-05-16 |
2009-11-05 |
Nurith Kurn |
Nucleic acid separation and purification method based on reversible charge interactions
|
|
US20080131937A1
(en)
*
|
2006-06-22 |
2008-06-05 |
Applera Corporation |
Conversion of Target Specific Amplification to Universal Sequencing
|
|
US20100022403A1
(en)
|
2006-06-30 |
2010-01-28 |
Nurith Kurn |
Methods for fragmentation and labeling of nucleic acids
|
|
WO2008015396A2
(en)
|
2006-07-31 |
2008-02-07 |
Solexa Limited |
Method of library preparation avoiding the formation of adaptor dimers
|
|
WO2008033442A2
(en)
|
2006-09-12 |
2008-03-20 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for performing low background multiplex nucleic acid amplification reactions
|
|
US20080242560A1
(en)
|
2006-11-21 |
2008-10-02 |
Gunderson Kevin L |
Methods for generating amplified nucleic acid arrays
|
|
US8262900B2
(en)
|
2006-12-14 |
2012-09-11 |
Life Technologies Corporation |
Methods and apparatus for measuring analytes using large scale FET arrays
|
|
EP2639578B1
(en)
|
2006-12-14 |
2016-09-14 |
Life Technologies Corporation |
Apparatus for measuring analytes using large scale fet arrays
|
|
EP2121983A2
(en)
*
|
2007-02-02 |
2009-11-25 |
Illumina Cambridge Limited |
Methods for indexing samples and sequencing multiple nucleotide templates
|
|
US20080194416A1
(en)
|
2007-02-08 |
2008-08-14 |
Sigma Aldrich |
Detection of mature small rna molecules
|
|
WO2008112653A1
(en)
|
2007-03-09 |
2008-09-18 |
Dxtech, Llc |
Electrochemical detection system
|
|
US20080241831A1
(en)
|
2007-03-28 |
2008-10-02 |
Jian-Bing Fan |
Methods for detecting small RNA species
|
|
WO2008137661A1
(en)
|
2007-05-03 |
2008-11-13 |
Helicos Biosciences Corporation |
Methods and compositions for sequencing a nucleic acid
|
|
US9248076B2
(en)
|
2007-05-16 |
2016-02-02 |
Mystic Pharmaceuticals, Inc. |
Dose dispensing containers
|
|
JP2010528608A
(ja)
*
|
2007-06-01 |
2010-08-26 |
４５４ ライフ サイエンシーズ コーポレイション |
複合的な混合物から個々の試料を特定するためのシステムおよび方法
|
|
CA2689626C
(en)
|
2007-06-06 |
2016-10-25 |
Pacific Biosciences Of California, Inc. |
Methods and processes for calling bases in sequence by incorporation methods
|
|
AR066922A1
(es)
|
2007-06-08 |
2009-09-23 |
Monsanto Technology Llc |
Metodos de mejoramiento molecular del germoplasma de una planta por secuenciamiento dirigido
|
|
EP2183388A4
(en)
|
2007-07-26 |
2010-09-08 |
Pacific Biosciences California |
SEQUENCING MOLECULAR REDUNDANT
|
|
US8748100B2
(en)
|
2007-08-30 |
2014-06-10 |
The Chinese University Of Hong Kong |
Methods and kits for selectively amplifying, detecting or quantifying target DNA with specific end sequences
|
|
US9388457B2
(en)
|
2007-09-14 |
2016-07-12 |
Affymetrix, Inc. |
Locus specific amplification using array probes
|
|
EP2053132A1
(en)
|
2007-10-23 |
2009-04-29 |
Roche Diagnostics GmbH |
Enrichment and sequence analysis of geomic regions
|
|
CN102124126A
(zh)
|
2007-10-26 |
2011-07-13 |
生命技术公司 |
使用非随机引物的cdna合成
|
|
US8518640B2
(en)
|
2007-10-29 |
2013-08-27 |
Complete Genomics, Inc. |
Nucleic acid sequencing and process
|
|
US20090203531A1
(en)
|
2008-02-12 |
2009-08-13 |
Nurith Kurn |
Method for Archiving and Clonal Expansion
|
|
EP2247727A4
(en)
|
2008-02-12 |
2011-08-03 |
Nugen Technologies Inc |
PROCESS FOR ARCHIVING AND CLONING EXPANSION
|
|
GB0804690D0
(en)
|
2008-03-13 |
2008-04-16 |
Netherlands Cancer Inst The |
Method
|
|
WO2009117698A2
(en)
|
2008-03-21 |
2009-09-24 |
Nugen Technologies, Inc. |
Methods of rna amplification in the presence of dna
|
|
WO2009120374A2
(en)
|
2008-03-28 |
2009-10-01 |
Pacific Biosciences Of California, Inc. |
Methods and compositions for nucleic acid sample preparation
|
|
EP3045542B1
(en)
|
2008-03-28 |
2016-11-16 |
Pacific Biosciences of California, Inc. |
Methods for nucleic acid sequencing
|
|
WO2009124255A2
(en)
|
2008-04-04 |
2009-10-08 |
Helicos Biosciences Corporation |
Methods for transcript analysis
|
|
WO2010003153A2
(en)
|
2008-07-03 |
2010-01-07 |
Life Technologies Corporation |
Methylation analysis of mate pairs
|
|
JP5221248B2
(ja)
|
2008-08-26 |
2013-06-26 |
株式会社日立ハイテクノロジーズ |
高発現遺伝子由来のｃＤＮＡクローンの含有率を低減させたｃＤＮＡライブラリーの作製方法
|
|
CN102203273A
(zh)
|
2008-09-09 |
2011-09-28 |
生命技术公司 |
生成基因特异性的文库的方法
|
|
US9156010B2
(en)
|
2008-09-23 |
2015-10-13 |
Bio-Rad Laboratories, Inc. |
Droplet-based assay system
|
|
WO2010039991A2
(en)
|
2008-10-02 |
2010-04-08 |
The Texas A&M University System |
Method of generating informative dna templates for high-throughput sequencing applications
|
|
US20100137143A1
(en)
|
2008-10-22 |
2010-06-03 |
Ion Torrent Systems Incorporated |
Methods and apparatus for measuring analytes
|
|
US20100113296A1
(en)
|
2008-11-05 |
2010-05-06 |
Joel Myerson |
Methods And Kits For Nucleic Acid Analysis
|
|
US8017328B2
(en)
|
2008-11-21 |
2011-09-13 |
Agilent Technologies, Inc. |
Genome partitioning using a nicking endonuclease
|
|
GB2465986A
(en)
|
2008-12-04 |
2010-06-09 |
Angeletti P Ist Richerche Bio |
Method of generating diversity in polynucleotide sequences
|
|
EP2367937B1
(en)
|
2008-12-04 |
2013-04-17 |
Keygene N.V. |
Method for the reduction of repetitive sequences in adapter-ligated restriction fragments
|
|
EP2389454B1
(en)
|
2009-01-22 |
2017-09-20 |
QIAGEN Beverly, Inc. |
Method for enrichment of selected rna molecules
|
|
US20100323348A1
(en)
|
2009-01-31 |
2010-12-23 |
The Regents Of The University Of Colorado, A Body Corporate |
Methods and Compositions for Using Error-Detecting and/or Error-Correcting Barcodes in Nucleic Acid Amplification Process
|
|
EP2393717A4
(en)
|
2009-02-06 |
2013-08-14 |
Univ Northwestern |
COLLECTABLE LIQUID PACKAGING AND ITS USE
|
|
EP2789694A1
(en)
|
2009-04-02 |
2014-10-15 |
Fluidigm Corporation |
Microfluidic device with reaction product recovery system
|
|
US20110003301A1
(en)
|
2009-05-08 |
2011-01-06 |
Life Technologies Corporation |
Methods for detecting genetic variations in dna samples
|
|
US20120156728A1
(en)
|
2010-12-17 |
2012-06-21 |
Life Technologies Corporation |
Clonal amplification of nucleic acid on solid surface with template walking
|
|
CN101565746B
(zh)
*
|
2009-06-03 |
2012-08-08 |
东南大学 |
带奇偶校验的信号组合编码dna连接测序方法
|
|
EP2272976A1
(en)
|
2009-07-06 |
2011-01-12 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Method for differentiation of polynucleotide strands
|
|
US8481699B2
(en)
|
2009-07-14 |
2013-07-09 |
Academia Sinica |
Multiplex barcoded Paired-End ditag (mbPED) library construction for ultra high throughput sequencing
|
|
GB0912909D0
(en)
|
2009-07-23 |
2009-08-26 |
Olink Genomics Ab |
Probes for specific analysis of nucleic acids
|
|
WO2011019964A1
(en)
|
2009-08-12 |
2011-02-17 |
Nugen Technologies, Inc. |
Methods, compositions, and kits for generating nucleic acid products substantially free of template nucleic acid
|
|
CN102858995B
(zh)
*
|
2009-09-10 |
2016-10-26 |
森特瑞隆技术控股公司 |
靶向测序方法
|
|
US20110189679A1
(en)
|
2009-09-11 |
2011-08-04 |
Nugen Technologies, Inc. |
Compositions and methods for whole transcriptome analysis
|
|
GB2487341A
(en)
|
2009-11-02 |
2012-07-18 |
Nugen Technologies Inc |
Compositions and methods for targeted nucleic acid sequence selection and amplification
|
|
WO2011055232A2
(en)
|
2009-11-04 |
2011-05-12 |
Population Genetics Technologies Ltd. |
Base-by-base mutation screening
|
|
WO2011056866A2
(en)
|
2009-11-05 |
2011-05-12 |
Epicentre Technologies Corporation |
Methods and kits for 3'-end-tagging of rna
|
|
GB0921264D0
(en)
|
2009-12-03 |
2010-01-20 |
Olink Genomics Ab |
Method for amplification of target nucleic acid
|
|
US20110269647A1
(en)
*
|
2010-04-28 |
2011-11-03 |
Medical Research Council |
Method
|
|
AU2011255641A1
(en)
|
2010-05-18 |
2012-12-06 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
ITRM20100293A1
(it)
|
2010-05-31 |
2011-12-01 |
Consiglio Nazionale Ricerche |
Metodo per la preparazione e amplificazione di librerie rappresentative di cdna per il sequenziamento massivo, loro uso, kit e cartucce per kit di automazione
|
|
CN103119439A
(zh)
|
2010-06-08 |
2013-05-22 |
纽亘技术公司 |
用于多重测序的方法和组合物
|
|
EP4242327A3
(en)
*
|
2010-06-09 |
2023-11-29 |
Keygene N.V. |
Combinatorial sequence barcodes for high throughput screening
|
|
US20120003657A1
(en)
|
2010-07-02 |
2012-01-05 |
Samuel Myllykangas |
Targeted sequencing library preparation by genomic dna circularization
|
|
US20120238738A1
(en)
|
2010-07-19 |
2012-09-20 |
New England Biolabs, Inc. |
Oligonucleotide Adapters: Compositions and Methods of Use
|
|
GB201012748D0
(en)
|
2010-07-29 |
2010-09-15 |
Univ St Andrews |
Improved RACE
|
|
ES2523140T3
(es)
*
|
2010-09-21 |
2014-11-21 |
Population Genetics Technologies Ltd. |
Aumento de la confianza en las identificaciones de alelos con el recuento molecular
|
|
CN103228798B
(zh)
|
2010-09-24 |
2015-12-09 |
斯坦福大学托管董事会 |
使用固定的引物直接捕获、扩增及测序靶标dna
|
|
US8715933B2
(en)
|
2010-09-27 |
2014-05-06 |
Nabsys, Inc. |
Assay methods using nicking endonucleases
|
|
DK2630263T4
(da)
*
|
2010-10-22 |
2022-02-14 |
Cold Spring Harbor Laboratory |
Varital tælling af nucleinsyrer for at opnå information om antal genomiske kopier
|
|
US20120102054A1
(en)
|
2010-10-25 |
2012-04-26 |
Life Technologies Corporation |
Systems and Methods for Annotating Biomolecule Data
|
|
US8829171B2
(en)
|
2011-02-10 |
2014-09-09 |
Illumina, Inc. |
Linking sequence reads using paired code tags
|
|
CA2821299C
(en)
|
2010-11-05 |
2019-02-12 |
Frank J. Steemers |
Linking sequence reads using paired code tags
|
|
CA2821906C
(en)
|
2010-12-22 |
2020-08-25 |
Natera, Inc. |
Methods for non-invasive prenatal paternity testing
|
|
US9163281B2
(en)
*
|
2010-12-23 |
2015-10-20 |
Good Start Genetics, Inc. |
Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction
|
|
WO2012103154A1
(en)
|
2011-01-24 |
2012-08-02 |
Nugen Technologies, Inc. |
Stem-loop composite rna-dna adaptor-primers: compositions and methods for library generation, amplification and other downstream manipulations
|
|
CA2824387C
(en)
|
2011-02-09 |
2019-09-24 |
Natera, Inc. |
Methods for non-invasive prenatal ploidy calling
|
|
EP2675819B1
(en)
*
|
2011-02-18 |
2020-04-08 |
Bio-Rad Laboratories, Inc. |
Compositions and methods for molecular labeling
|
|
US20130059738A1
(en)
|
2011-04-28 |
2013-03-07 |
Life Technologies Corporation |
Methods and compositions for multiplex pcr
|
|
US8722585B2
(en)
|
2011-05-08 |
2014-05-13 |
Yan Wang |
Methods of making di-tagged DNA libraries from DNA or RNA using double-tagged oligonucleotides
|
|
US9074204B2
(en)
|
2011-05-20 |
2015-07-07 |
Fluidigm Corporation |
Nucleic acid encoding reactions
|
|
US8841071B2
(en)
|
2011-06-02 |
2014-09-23 |
Raindance Technologies, Inc. |
Sample multiplexing
|
|
SG11201401628WA
(en)
|
2011-10-19 |
2014-05-29 |
Nugen Technologies Inc |
Compositions and methods for directional nucleic acid amplification and sequencing
|
|
WO2013059740A1
(en)
|
2011-10-21 |
2013-04-25 |
Foundation Medicine, Inc. |
Novel alk and ntrk1 fusion molecules and uses thereof
|
|
SG10201504490QA
(en)
|
2012-01-26 |
2015-07-30 |
Nugen Technologies Inc |
Compositions And Methods For Targeted Nucleic Acid Sequence Enrichment And High Efficiency Library Generation
|
|
US20160153039A1
(en)
|
2012-01-26 |
2016-06-02 |
Nugen Technologies, Inc. |
Compositions and methods for targeted nucleic acid sequence enrichment and high efficiency library generation
|
|
US11177020B2
(en)
*
|
2012-02-27 |
2021-11-16 |
The University Of North Carolina At Chapel Hill |
Methods and uses for molecular tags
|
|
CA2865575C
(en)
|
2012-02-27 |
2024-01-16 |
Cellular Research, Inc. |
Compositions and kits for molecular counting
|
|
CA2867293C
(en)
*
|
2012-03-13 |
2020-09-01 |
Abhijit Ajit PATEL |
Measurement of nucleic acid variants using highly-multiplexed error-suppressed deep sequencing
|
|
US8209130B1
(en)
|
2012-04-04 |
2012-06-26 |
Good Start Genetics, Inc. |
Sequence assembly
|
|
WO2013177220A1
(en)
|
2012-05-21 |
2013-11-28 |
The Scripps Research Institute |
Methods of sample preparation
|
|
US9957549B2
(en)
|
2012-06-18 |
2018-05-01 |
Nugen Technologies, Inc. |
Compositions and methods for negative selection of non-desired nucleic acid sequences
|
|
US11261494B2
(en)
|
2012-06-21 |
2022-03-01 |
The Chinese University Of Hong Kong |
Method of measuring a fractional concentration of tumor DNA
|
|
US20150011396A1
(en)
|
2012-07-09 |
2015-01-08 |
Benjamin G. Schroeder |
Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
|
|
US20140378345A1
(en)
|
2012-08-14 |
2014-12-25 |
10X Technologies, Inc. |
Compositions and methods for sample processing
|
|
IL269097B2
(en)
|
2012-09-04 |
2024-01-01 |
Guardant Health Inc |
Systems and methods to detect rare mutations and copy number variation
|
|
ES2675618T3
(es)
|
2012-11-26 |
2018-07-11 |
The University Of Toledo |
Métodos para la secuenciación estandarizada de ácidos nucleicos y usos de los mismos
|
|
HK1213944A1
(zh)
|
2012-12-10 |
2016-07-15 |
Resolution Bioscience, Inc. |
用於靶向基因组分析
|
|
US20140274729A1
(en)
|
2013-03-15 |
2014-09-18 |
Nugen Technologies, Inc. |
Methods, compositions and kits for generation of stranded rna or dna libraries
|
|
US20140274738A1
(en)
|
2013-03-15 |
2014-09-18 |
Nugen Technologies, Inc. |
Sequential sequencing
|
|
ES2857908T3
(es)
|
2013-08-28 |
2021-09-29 |
Becton Dickinson Co |
Análisis masivamente paralelo de células individuales
|
|
EP3057627B1
(en)
|
2013-10-15 |
2018-07-25 |
Mystic Pharmaceuticals, Inc. |
Controllable rate turbulating nozzle
|
|
WO2015073711A1
(en)
|
2013-11-13 |
2015-05-21 |
Nugen Technologies, Inc. |
Compositions and methods for identification of a duplicate sequencing read
|
|
GB201320542D0
(en)
|
2013-11-21 |
2014-01-01 |
Randox Lab Ltd |
Assay fluid delivery system
|
|
WO2015131107A1
(en)
|
2014-02-28 |
2015-09-03 |
Nugen Technologies, Inc. |
Reduced representation bisulfite sequencing with diversity adaptors
|
|
JP6803327B2
(ja)
|
2014-08-06 |
2020-12-23 |
ニューゲン テクノロジーズ， インコーポレイテッド |
標的化されたシークエンシングからのデジタル測定値
|
|
US9527077B2
(en)
|
2015-01-29 |
2016-12-27 |
David W. Wright |
Diagnostic cartridge, fluid storage and delivery apparatus therefor and methods of construction thereof
|
|
US20160275240A1
(en)
|
2015-02-18 |
2016-09-22 |
Nugen Technologies, Inc. |
Methods and compositions for pooling amplification primers
|
|
CN105890722A
(zh)
|
2016-06-13 |
2016-08-24 |
常州大学 |
利用共振原理测量dna分子质量的方法
|
|
US20220145380A1
(en)
*
|
2019-01-31 |
2022-05-12 |
Children's Medical Center Corporation |
Cost-effective detection of low frequency genetic variation
|