JP2017537609A5 - - Google Patents
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- Publication number
- JP2017537609A5 JP2017537609A5 JP2017519306A JP2017519306A JP2017537609A5 JP 2017537609 A5 JP2017537609 A5 JP 2017537609A5 JP 2017519306 A JP2017519306 A JP 2017519306A JP 2017519306 A JP2017519306 A JP 2017519306A JP 2017537609 A5 JP2017537609 A5 JP 2017537609A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- nucleic acids
- library
- block
- native
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108020004707 nucleic acids Proteins 0.000 claims 86
- 150000007523 nucleic acids Chemical class 0.000 claims 86
- 102000039446 nucleic acids Human genes 0.000 claims 86
- 108091093088 Amplicon Proteins 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 2
- 238000002844 melting Methods 0.000 claims 2
- 230000008018 melting Effects 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 230000003321 amplification Effects 0.000 claims 1
- 238000003199 nucleic acid amplification method Methods 0.000 claims 1
- 238000012163 sequencing technique Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462062612P | 2014-10-10 | 2014-10-10 | |
| US201462062616P | 2014-10-10 | 2014-10-10 | |
| US62/062,612 | 2014-10-10 | ||
| US62/062,616 | 2014-10-10 | ||
| PCT/IB2015/057679 WO2016055956A1 (en) | 2014-10-10 | 2015-10-08 | Universal blocking oligo system and improved hybridization capture methods for multiplexed capture reactions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017537609A JP2017537609A (ja) | 2017-12-21 |
| JP2017537609A5 true JP2017537609A5 (enExample) | 2018-11-22 |
| JP6722179B2 JP6722179B2 (ja) | 2020-07-15 |
Family
ID=55652677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017519306A Expired - Fee Related JP6722179B2 (ja) | 2014-10-10 | 2015-10-08 | 多重キャプチャー反応のためのユニバーサルブロッキングオリゴシステム及び改良されたハイブリダイゼーションキャプチャー方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10648103B2 (enExample) |
| EP (1) | EP3204518B1 (enExample) |
| JP (1) | JP6722179B2 (enExample) |
| CN (1) | CN107109485B (enExample) |
| CA (1) | CA2964069A1 (enExample) |
| IL (1) | IL251661B (enExample) |
| WO (1) | WO2016055956A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI695067B (zh) | 2013-08-05 | 2020-06-01 | 美商扭轉生物科技有限公司 | 重新合成之基因庫 |
| WO2016126882A1 (en) | 2015-02-04 | 2016-08-11 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
| WO2016172377A1 (en) | 2015-04-21 | 2016-10-27 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
| CN108368482A (zh) | 2015-09-18 | 2018-08-03 | 特韦斯特生物科学公司 | 寡核酸变体文库及其合成 |
| US11512347B2 (en) | 2015-09-22 | 2022-11-29 | Twist Bioscience Corporation | Flexible substrates for nucleic acid synthesis |
| WO2017095958A1 (en) | 2015-12-01 | 2017-06-08 | Twist Bioscience Corporation | Functionalized surfaces and preparation thereof |
| GB2568444A (en) | 2016-08-22 | 2019-05-15 | Twist Bioscience Corp | De novo synthesized nucleic acid libraries |
| EP3516528B1 (en) | 2016-09-21 | 2025-10-15 | Atlas Data Storage, Inc. | Nucleic acid based data storage |
| CA3047128A1 (en) | 2016-12-16 | 2018-06-21 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
| JP2020508661A (ja) | 2017-02-22 | 2020-03-26 | ツイスト バイオサイエンス コーポレーション | 核酸ベースのデータ保存 |
| CA3056388A1 (en) | 2017-03-15 | 2018-09-20 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
| WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| WO2018231872A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| US11407837B2 (en) | 2017-09-11 | 2022-08-09 | Twist Bioscience Corporation | GPCR binding proteins and synthesis thereof |
| CA3079613A1 (en) | 2017-10-20 | 2019-04-25 | Twist Bioscience Corporation | Heated nanowells for polynucleotide synthesis |
| KR20250069684A (ko) | 2018-01-04 | 2025-05-19 | 트위스트 바이오사이언스 코포레이션 | Dna 기반 디지털 정보 저장 |
| CN118957038A (zh) | 2018-05-18 | 2024-11-15 | 特韦斯特生物科学公司 | 用于核酸杂交的多核苷酸、试剂和方法 |
| WO2019232291A1 (en) * | 2018-05-31 | 2019-12-05 | Massachusetts Institute Of Technology | Drug delivery articles for gram-level dosing |
| EP3837381A1 (en) | 2018-08-15 | 2021-06-23 | Illumina, Inc. | Compositions and methods for improving library enrichment |
| WO2020139871A1 (en) | 2018-12-26 | 2020-07-02 | Twist Bioscience Corporation | Highly accurate de novo polynucleotide synthesis |
| JP2022521766A (ja) * | 2019-02-25 | 2022-04-12 | ツイスト バイオサイエンス コーポレーション | 次世代シーケンシングのための組成物および方法 |
| JP2022521551A (ja) | 2019-02-26 | 2022-04-08 | ツイスト バイオサイエンス コーポレーション | Ｇｌｐ１受容体の変異体核酸ライブラリ |
| US11492728B2 (en) | 2019-02-26 | 2022-11-08 | Twist Bioscience Corporation | Variant nucleic acid libraries for antibody optimization |
| WO2020257612A1 (en) | 2019-06-21 | 2020-12-24 | Twist Bioscience Corporation | Barcode-based nucleic acid sequence assembly |
| WO2020259678A1 (zh) * | 2019-06-26 | 2020-12-30 | 南京金斯瑞生物科技有限公司 | 一种含有阻断物的寡核苷酸 |
| US12173282B2 (en) | 2019-09-23 | 2024-12-24 | Twist Bioscience, Inc. | Antibodies that bind CD3 epsilon |
| CN115003697A (zh) | 2019-09-23 | 2022-09-02 | 特韦斯特生物科学公司 | Crth2的变异核酸文库 |
| US11718848B1 (en) * | 2020-05-29 | 2023-08-08 | Color Health, Inc. | Methods for depletion of high-copy sequences in multiplexed whole genome sequencing libraries |
| CN111961711A (zh) * | 2020-08-31 | 2020-11-20 | 伯科生物科技有限公司 | 用于靶向测序的通用杂交增强剂及方法 |
| US20220282398A1 (en) * | 2021-03-05 | 2022-09-08 | Bioo Scientific Corporation | Universal blocking oligonucleotides for reduced off-target hybridization in hybridization capture methods |
| US20250171832A1 (en) * | 2021-09-30 | 2025-05-29 | Illumina, Inc. | Blocker methods |
| US20250122495A1 (en) * | 2022-11-02 | 2025-04-17 | Boe Technology Group Co., Ltd. | Blockers, Kits and Methods of Use Thereof |
| CN116200477A (zh) * | 2022-12-13 | 2023-06-02 | 成都齐碳科技有限公司 | 包含联合阻滞元件的衔接体、构建体、方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0324456D0 (en) | 2003-10-20 | 2003-11-19 | Isis Innovation | Parallel DNA sequencing methods |
| US20140243232A1 (en) * | 2011-07-14 | 2014-08-28 | Life Technologies Corporation | Nucleic acid complexity reduction |
| EP2872629B1 (en) | 2012-07-03 | 2019-09-04 | Integrated DNA Technologies Inc. | Tm-enhanced blocking oligonucleotides and baits for improved target enrichment and reduced off-target selection |
-
2015
- 2015-10-08 US US15/514,957 patent/US10648103B2/en active Active
- 2015-10-08 EP EP15849044.1A patent/EP3204518B1/en not_active Not-in-force
- 2015-10-08 JP JP2017519306A patent/JP6722179B2/ja not_active Expired - Fee Related
- 2015-10-08 CN CN201580066291.7A patent/CN107109485B/zh not_active Expired - Fee Related
- 2015-10-08 WO PCT/IB2015/057679 patent/WO2016055956A1/en not_active Ceased
- 2015-10-08 CA CA2964069A patent/CA2964069A1/en not_active Abandoned
-
2017
- 2017-04-09 IL IL251661A patent/IL251661B/en unknown