CN107109485B - 用于多重捕获反应的通用阻断寡聚物系统和改进的杂交捕获的方法 - Google Patents

用于多重捕获反应的通用阻断寡聚物系统和改进的杂交捕获的方法 Download PDF

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CN107109485B
CN107109485B CN201580066291.7A CN201580066291A CN107109485B CN 107109485 B CN107109485 B CN 107109485B CN 201580066291 A CN201580066291 A CN 201580066291A CN 107109485 B CN107109485 B CN 107109485B
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CN107109485A (zh
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E·奥利瓦瑞斯
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Invitae Corp
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CN201580066291.7A 2014-10-10 2015-10-08 用于多重捕获反应的通用阻断寡聚物系统和改进的杂交捕获的方法 Expired - Fee Related CN107109485B (zh)

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Application Number Priority Date Filing Date Title
US201462062612P 2014-10-10 2014-10-10
US201462062616P 2014-10-10 2014-10-10
US62/062,616 2014-10-10
US62/062,612 2014-10-10
PCT/IB2015/057679 WO2016055956A1 (en) 2014-10-10 2015-10-08 Universal blocking oligo system and improved hybridization capture methods for multiplexed capture reactions

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CN107109485A CN107109485A (zh) 2017-08-29
CN107109485B true CN107109485B (zh) 2020-12-08

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JP (1) JP6722179B2 (enExample)
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CA (1) CA2964069A1 (enExample)
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WO2016172377A1 (en) 2015-04-21 2016-10-27 Twist Bioscience Corporation Devices and methods for oligonucleic acid library synthesis
AU2016324296A1 (en) 2015-09-18 2018-04-12 Twist Bioscience Corporation Oligonucleic acid variant libraries and synthesis thereof
CN108698012A (zh) 2015-09-22 2018-10-23 特韦斯特生物科学公司 用于核酸合成的柔性基底
CN108603307A (zh) 2015-12-01 2018-09-28 特韦斯特生物科学公司 功能化表面及其制备
CA3034769A1 (en) 2016-08-22 2018-03-01 Twist Bioscience Corporation De novo synthesized nucleic acid libraries
CN110248724B (zh) 2016-09-21 2022-11-18 特韦斯特生物科学公司 基于核酸的数据存储
CN110366613A (zh) 2016-12-16 2019-10-22 特韦斯特生物科学公司 免疫突触的变体文库及其合成
WO2018156792A1 (en) 2017-02-22 2018-08-30 Twist Bioscience Corporation Nucleic acid based data storage
CN110913865A (zh) 2017-03-15 2020-03-24 特韦斯特生物科学公司 免疫突触的变体文库及其合成
WO2018231864A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
IL271205B2 (en) 2017-06-12 2025-02-01 Twist Bioscience Corp Methods for assembling continuous nucleic acids
US11407837B2 (en) 2017-09-11 2022-08-09 Twist Bioscience Corporation GPCR binding proteins and synthesis thereof
KR102637566B1 (ko) 2017-10-20 2024-02-16 트위스트 바이오사이언스 코포레이션 폴리뉴클레오타이드 합성을 위한 가열된 나노웰
CN112041438B (zh) 2018-01-04 2025-05-23 特韦斯特生物科学公司 基于dna的数字信息存储
CA3100739A1 (en) 2018-05-18 2019-11-21 Twist Bioscience Corporation Polynucleotides, reagents, and methods for nucleic acid hybridization
US20190365645A1 (en) * 2018-05-31 2019-12-05 Massachusetts Institute Of Technology Drug delivery articles for gram-level dosing
MY207240A (en) * 2018-08-15 2025-02-08 Illumina Inc Composition and method for improving library enrichment
CA3124980A1 (en) 2018-12-26 2020-07-02 Twist Bioscience Corporation Highly accurate de novo polynucleotide synthesis
US20210002710A1 (en) * 2019-02-25 2021-01-07 Twist Bioscience Corporation Compositions and methods for next generation sequencing
CN113785057A (zh) 2019-02-26 2021-12-10 特韦斯特生物科学公司 用于抗体优化的变异核酸文库
KR20210143766A (ko) 2019-02-26 2021-11-29 트위스트 바이오사이언스 코포레이션 Glp1 수용체에 대한 변이체 핵산 라이브러리
JP2022550497A (ja) 2019-06-21 2022-12-02 ツイスト バイオサイエンス コーポレーション バーコードに基づいた核酸配列アセンブリ
CN114040983A (zh) * 2019-06-26 2022-02-11 南京金斯瑞生物科技有限公司 一种含有阻断物的寡核苷酸
AU2020355027A1 (en) 2019-09-23 2022-04-21 Twist Bioscience Corporation Antibodies that bind CD3 Epsilon
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US11718848B1 (en) * 2020-05-29 2023-08-08 Color Health, Inc. Methods for depletion of high-copy sequences in multiplexed whole genome sequencing libraries
CN111961711A (zh) * 2020-08-31 2020-11-20 伯科生物科技有限公司 用于靶向测序的通用杂交增强剂及方法
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US10648103B2 (en) 2020-05-12
EP3204518A4 (en) 2018-03-21
CA2964069A1 (en) 2016-04-14
EP3204518B1 (en) 2019-07-10
JP2017537609A (ja) 2017-12-21
EP3204518A1 (en) 2017-08-16
JP6722179B2 (ja) 2020-07-15
IL251661B (en) 2021-12-01
CN107109485A (zh) 2017-08-29
IL251661A0 (en) 2017-06-29
WO2016055956A1 (en) 2016-04-14
US20170218537A1 (en) 2017-08-03

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