CN107109485B - 用于多重捕获反应的通用阻断寡聚物系统和改进的杂交捕获的方法 - Google Patents

用于多重捕获反应的通用阻断寡聚物系统和改进的杂交捕获的方法 Download PDF

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CN107109485B
CN107109485B CN201580066291.7A CN201580066291A CN107109485B CN 107109485 B CN107109485 B CN 107109485B CN 201580066291 A CN201580066291 A CN 201580066291A CN 107109485 B CN107109485 B CN 107109485B
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nucleic acid
nucleic acids
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CN107109485A (zh
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E·奥利瓦瑞斯
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Invitae Corp
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CN201580066291.7A 2014-10-10 2015-10-08 用于多重捕获反应的通用阻断寡聚物系统和改进的杂交捕获的方法 Expired - Fee Related CN107109485B (zh)

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Application Number Priority Date Filing Date Title
US201462062616P 2014-10-10 2014-10-10
US201462062612P 2014-10-10 2014-10-10
US62/062,616 2014-10-10
US62/062,612 2014-10-10
PCT/IB2015/057679 WO2016055956A1 (en) 2014-10-10 2015-10-08 Universal blocking oligo system and improved hybridization capture methods for multiplexed capture reactions

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CN107109485A CN107109485A (zh) 2017-08-29
CN107109485B true CN107109485B (zh) 2020-12-08

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US (1) US10648103B2 (enExample)
EP (1) EP3204518B1 (enExample)
JP (1) JP6722179B2 (enExample)
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CA (1) CA2964069A1 (enExample)
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KR20180050411A (ko) 2015-09-18 2018-05-14 트위스트 바이오사이언스 코포레이션 올리고핵산 변이체 라이브러리 및 그의 합성
WO2017053450A1 (en) 2015-09-22 2017-03-30 Twist Bioscience Corporation Flexible substrates for nucleic acid synthesis
EP3384077A4 (en) 2015-12-01 2019-05-08 Twist Bioscience Corporation FUNCTIONALIZED SURFACES AND MANUFACTURE THEREOF
WO2018038772A1 (en) 2016-08-22 2018-03-01 Twist Bioscience Corporation De novo synthesized nucleic acid libraries
EP4664304A3 (en) 2016-09-21 2026-01-21 Atlas Data Storage, Inc. Nucleic acid based data storage
GB2573069A (en) 2016-12-16 2019-10-23 Twist Bioscience Corp Variant libraries of the immunological synapse and synthesis thereof
WO2018156792A1 (en) 2017-02-22 2018-08-30 Twist Bioscience Corporation Nucleic acid based data storage
CA3056388A1 (en) 2017-03-15 2018-09-20 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
IL271205B2 (en) 2017-06-12 2025-02-01 Twist Bioscience Corp Methods for assembling continuous nucleic acids
WO2018231864A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
CN111566125A (zh) 2017-09-11 2020-08-21 特韦斯特生物科学公司 Gpcr结合蛋白及其合成
CN111565834B (zh) 2017-10-20 2022-08-26 特韦斯特生物科学公司 用于多核苷酸合成的加热的纳米孔
IL312616B2 (en) 2018-01-04 2025-08-01 Twist Bioscience Corp Dna-based digital information storage
EP3814497A4 (en) 2018-05-18 2022-03-02 Twist Bioscience Corporation POLYNUCLEOTIDES, REAGENTS AND METHODS FOR NUCLEIC ACID HYBRIDIZATION
WO2019232291A1 (en) * 2018-05-31 2019-12-05 Massachusetts Institute Of Technology Drug delivery articles for gram-level dosing
JP7431802B2 (ja) 2018-08-15 2024-02-15 イルミナ インコーポレイテッド ライブラリー富化を改善するための組成物および方法
EP3902816A4 (en) 2018-12-26 2022-09-14 Twist Bioscience Corporation HIGH-PRECISION DE NOVO POLYNUCLEOTIDE SYNTHESIS
CN113728100A (zh) * 2019-02-25 2021-11-30 特韦斯特生物科学公司 用于下一代测序的组合物和方法
CA3131689A1 (en) 2019-02-26 2020-09-03 Twist Bioscience Corporation Variant nucleic acid libraries for glp1 receptor
KR20210144698A (ko) 2019-02-26 2021-11-30 트위스트 바이오사이언스 코포레이션 항체 최적화를 위한 변이 핵산 라이브러리
EP3987019A4 (en) 2019-06-21 2023-04-19 Twist Bioscience Corporation Barcode-based nucleic acid sequence assembly
CN114040983A (zh) * 2019-06-26 2022-02-11 南京金斯瑞生物科技有限公司 一种含有阻断物的寡核苷酸
CN115023440B (zh) 2019-09-23 2025-09-12 特韦斯特生物科学公司 结合CD3ε的抗体
US12091777B2 (en) 2019-09-23 2024-09-17 Twist Bioscience Corporation Variant nucleic acid libraries for CRTH2
AU2020400030B2 (en) 2019-12-09 2026-05-21 Twist Bioscience Corporation Variant nucleic acid libraries for adenosine receptors
US11718848B1 (en) * 2020-05-29 2023-08-08 Color Health, Inc. Methods for depletion of high-copy sequences in multiplexed whole genome sequencing libraries
CN111961711A (zh) * 2020-08-31 2020-11-20 伯科生物科技有限公司 用于靶向测序的通用杂交增强剂及方法
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US10648103B2 (en) 2020-05-12
JP2017537609A (ja) 2017-12-21
CA2964069A1 (en) 2016-04-14
EP3204518A4 (en) 2018-03-21
CN107109485A (zh) 2017-08-29
IL251661A0 (en) 2017-06-29
JP6722179B2 (ja) 2020-07-15
WO2016055956A1 (en) 2016-04-14
EP3204518B1 (en) 2019-07-10
US20170218537A1 (en) 2017-08-03
IL251661B (en) 2021-12-01
EP3204518A1 (en) 2017-08-16

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