JP2014513557A5 - - Google Patents
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- JP2014513557A5 JP2014513557A5 JP2014511555A JP2014511555A JP2014513557A5 JP 2014513557 A5 JP2014513557 A5 JP 2014513557A5 JP 2014511555 A JP2014511555 A JP 2014511555A JP 2014511555 A JP2014511555 A JP 2014511555A JP 2014513557 A5 JP2014513557 A5 JP 2014513557A5
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- JP
- Japan
- Prior art keywords
- target
- probe
- nucleic acid
- linking
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000523 sample Substances 0.000 claims 37
- 150000007523 nucleic acids Chemical class 0.000 claims 23
- 238000000034 method Methods 0.000 claims 22
- 108020004707 nucleic acids Proteins 0.000 claims 17
- 102000039446 nucleic acids Human genes 0.000 claims 17
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 6
- 108091093088 Amplicon Proteins 0.000 claims 4
- 239000000758 substrate Substances 0.000 claims 4
- 102000003960 Ligases Human genes 0.000 claims 3
- 108090000364 Ligases Proteins 0.000 claims 3
- 238000001514 detection method Methods 0.000 claims 3
- 125000005647 linker group Chemical group 0.000 claims 3
- 125000006850 spacer group Chemical group 0.000 claims 3
- PJJJBBJSCAKJQF-UHFFFAOYSA-N guanidinium chloride Chemical compound [Cl-].NC(N)=[NH2+] PJJJBBJSCAKJQF-UHFFFAOYSA-N 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- 238000003390 bioluminescence detection Methods 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 238000005251 capillar electrophoresis Methods 0.000 claims 1
- 238000002038 chemiluminescence detection Methods 0.000 claims 1
- 238000000835 electrochemical detection Methods 0.000 claims 1
- 238000001378 electrochemiluminescence detection Methods 0.000 claims 1
- 238000001917 fluorescence detection Methods 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 238000004949 mass spectrometry Methods 0.000 claims 1
- 238000010208 microarray analysis Methods 0.000 claims 1
- 230000003287 optical effect Effects 0.000 claims 1
- 238000003753 real-time PCR Methods 0.000 claims 1
- 238000012163 sequencing technique Methods 0.000 claims 1
- RYYWUUFWQRZTIU-UHFFFAOYSA-K thiophosphate Chemical compound [O-]P([O-])([O-])=S RYYWUUFWQRZTIU-UHFFFAOYSA-K 0.000 claims 1
- 238000011144 upstream manufacturing Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161486817P | 2011-05-17 | 2011-05-17 | |
| US61/486,817 | 2011-05-17 | ||
| PCT/US2012/038436 WO2012158967A1 (en) | 2011-05-17 | 2012-05-17 | Methods and compositions for detecting target nucleic acids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014513557A JP2014513557A (ja) | 2014-06-05 |
| JP2014513557A5 true JP2014513557A5 (enExample) | 2015-05-21 |
Family
ID=46168641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014511555A Pending JP2014513557A (ja) | 2011-05-17 | 2012-05-17 | 標的核酸を検出する方法及び組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US10066257B2 (enExample) |
| EP (1) | EP2710145B1 (enExample) |
| JP (1) | JP2014513557A (enExample) |
| KR (1) | KR102085242B1 (enExample) |
| CN (2) | CN106434871B (enExample) |
| AU (1) | AU2012255121B2 (enExample) |
| CA (1) | CA2836577C (enExample) |
| DK (1) | DK2710145T3 (enExample) |
| WO (1) | WO2012158967A1 (enExample) |
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-
2012
- 2012-05-17 KR KR1020137033544A patent/KR102085242B1/ko active Active
- 2012-05-17 DK DK12723799.8T patent/DK2710145T3/en active
- 2012-05-17 US US13/474,596 patent/US10066257B2/en active Active
- 2012-05-17 US US14/118,524 patent/US9745616B2/en active Active
- 2012-05-17 JP JP2014511555A patent/JP2014513557A/ja active Pending
- 2012-05-17 CN CN201610651714.8A patent/CN106434871B/zh active Active
- 2012-05-17 CA CA2836577A patent/CA2836577C/en active Active
- 2012-05-17 AU AU2012255121A patent/AU2012255121B2/en active Active
- 2012-05-17 CN CN201280034508.2A patent/CN103827317B/zh active Active
- 2012-05-17 EP EP12723799.8A patent/EP2710145B1/en active Active
- 2012-05-17 WO PCT/US2012/038436 patent/WO2012158967A1/en not_active Ceased
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2017
- 2017-08-07 US US15/670,963 patent/US20180030520A1/en not_active Abandoned
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