JP2017532044A5 - - Google Patents
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- Publication number
- JP2017532044A5 JP2017532044A5 JP2017519832A JP2017519832A JP2017532044A5 JP 2017532044 A5 JP2017532044 A5 JP 2017532044A5 JP 2017519832 A JP2017519832 A JP 2017519832A JP 2017519832 A JP2017519832 A JP 2017519832A JP 2017532044 A5 JP2017532044 A5 JP 2017532044A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- sequence
- dna
- signal
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108091034117 Oligonucleotide Proteins 0.000 claims 20
- 238000000034 method Methods 0.000 claims 9
- 125000006850 spacer group Chemical group 0.000 claims 9
- 102000004533 Endonucleases Human genes 0.000 claims 8
- 108010042407 Endonucleases Proteins 0.000 claims 8
- 108020004707 nucleic acids Proteins 0.000 claims 8
- 150000007523 nucleic acids Chemical class 0.000 claims 8
- 102000039446 nucleic acids Human genes 0.000 claims 8
- 230000000295 complement effect Effects 0.000 claims 3
- 108700011259 MicroRNAs Proteins 0.000 claims 2
- 238000006243 chemical reaction Methods 0.000 claims 2
- 238000006073 displacement reaction Methods 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 239000012678 infectious agent Substances 0.000 claims 2
- 239000002679 microRNA Substances 0.000 claims 2
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 claims 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 claims 1
- 230000003321 amplification Effects 0.000 claims 1
- 238000003199 nucleic acid amplification method Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 238000005096 rolling process Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462063666P | 2014-10-14 | 2014-10-14 | |
| US62/063,666 | 2014-10-14 | ||
| US201462098066P | 2014-12-30 | 2014-12-30 | |
| US62/098,066 | 2014-12-30 | ||
| PCT/IB2015/002145 WO2016059474A2 (en) | 2014-10-14 | 2015-10-13 | Sequence conversion and signal amplifier dna having poly dna spacer sequences and detection methods using same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017532044A JP2017532044A (ja) | 2017-11-02 |
| JP2017532044A5 true JP2017532044A5 (enExample) | 2019-01-10 |
| JP6773651B2 JP6773651B2 (ja) | 2020-10-21 |
Family
ID=55655044
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017519832A Active JP6773651B2 (ja) | 2014-10-14 | 2015-10-13 | ポリｄｎａスペーサー配列を有する配列変換およびシグナル増幅ｄｎａならびにそれらを用いた検出方法 |
| JP2017519860A Active JP6896620B2 (ja) | 2014-10-14 | 2015-10-13 | ロックされた核酸を有する配列変換およびシグナル増幅ｄｎａならびにそれを用いた検出方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017519860A Active JP6896620B2 (ja) | 2014-10-14 | 2015-10-13 | ロックされた核酸を有する配列変換およびシグナル増幅ｄｎａならびにそれを用いた検出方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10208333B2 (enExample) |
| EP (2) | EP3207160B1 (enExample) |
| JP (2) | JP6773651B2 (enExample) |
| CN (2) | CN107109473B (enExample) |
| ES (2) | ES2759339T3 (enExample) |
| WO (2) | WO2016059474A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6126381B2 (ja) | 2010-12-10 | 2017-05-10 | 国立大学法人東京工業大学 | 標的核酸の検出方法及びキット |
| ES2754251T3 (es) | 2014-01-15 | 2020-04-16 | Abbott Lab | Secuencia cubierta de conversión de ADN y métodos de detección |
| US10208333B2 (en) | 2014-10-14 | 2019-02-19 | Abbott Laboratories | Sequence conversion and signal amplifier DNA having locked nucleic acids and detection methods using same |
| ES2791280T3 (es) | 2014-12-24 | 2020-11-03 | Abbott Lab | Método de detección, composición y kit basados en reacciones en cascada de ADN amplificador de señal con extensión de la diana |
| GB201611469D0 (en) | 2016-06-30 | 2016-08-17 | Lumiradx Tech Ltd | Improvements in or relating to nucleic acid amplification processes |
| GB2569965A (en) | 2018-01-04 | 2019-07-10 | Lumiradx Uk Ltd | Improvements in or relating to amplification of nucleic acids |
| CN116194591A (zh) * | 2020-06-10 | 2023-05-30 | 博纳迪诊断学有限责任公司 | 序列转换反应 |
| US20250197936A1 (en) * | 2021-12-09 | 2025-06-19 | Bonadea Diagnostics, Llc | Sequence conversion reaction |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
| JPH07114718A (ja) | 1993-10-18 | 1995-05-02 | Tanashin Denki Co | テープレコーダの回転ヘッド装置 |
| US5928869A (en) | 1997-05-30 | 1999-07-27 | Becton, Dickinson And Company | Detection of nucleic acids by fluorescence quenching |
| ES2393056T3 (es) | 1998-11-09 | 2012-12-18 | Eiken Kagaku Kabushiki Kaisha | Procedimiento de síntesis de ácido nucleico |
| US6316200B1 (en) | 2000-06-08 | 2001-11-13 | Becton, Dickinson And Company | Probes and methods for detection of nucleic acids |
| EA007414B1 (ru) | 2000-08-23 | 2006-10-27 | Такара Био Инк. | Химерный олигонуклеотидный праймер для способа амплификации нуклеиновой кислоты; продукт для амплификации нуклеиновой кислоты; зонд для способа детекции нуклеиновой кислоты-мишени; материал с иммобилизованной амплифицированной нуклеиновой кислотой и способ его получения; способ определения нуклеотидной последовательности |
| CA2492032A1 (en) | 2001-07-15 | 2003-08-14 | Keck Graduate Institute | Gene expression analysis using nicking agents |
| WO2003029459A2 (en) | 2001-09-28 | 2003-04-10 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Micro-rna molecules |
| AU2003235894A1 (en) | 2002-05-08 | 2003-12-12 | Arkray, Inc. | Method of detecting target nucleic acid |
| EP1543156A4 (en) * | 2002-07-18 | 2005-12-21 | Univ Leland Stanford Junior | DETECTION OF CHEMICAL LIGATION USING FLUORESCENCE QUENCHER SUB-GROUPS |
| WO2004067764A2 (en) | 2003-01-29 | 2004-08-12 | Keck Graduate Institute | Nucleic acid sequencing using nicking agents |
| WO2004067726A2 (en) | 2003-01-29 | 2004-08-12 | Keck Graduate Institute | Isothermal reactions for the amplification of oligonucleotides |
| WO2004067765A2 (en) | 2003-01-29 | 2004-08-12 | Keck Graduate Institute | Organism fingerprinting using nicking agents |
| WO2004074480A1 (ja) * | 2003-02-21 | 2004-09-02 | Eisai Co., Ltd. | 変異遺伝子検出のためのシグナル増幅方法 |
| CN101415838A (zh) * | 2003-09-26 | 2009-04-22 | 首科安普有限公司 | 用滚环扩增法扩增多核苷酸 |
| US20080311564A1 (en) | 2004-08-06 | 2008-12-18 | Fort Thomas L | Sequences and Methods for Detection of Cytomegalovirus |
| WO2008001376A2 (en) | 2006-06-28 | 2008-01-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Detection of analytes in a medium |
| US9689031B2 (en) | 2007-07-14 | 2017-06-27 | Ionian Technologies, Inc. | Nicking and extension amplification reaction for the exponential amplification of nucleic acids |
| WO2010068473A1 (en) | 2008-11-25 | 2010-06-17 | Gen-Probe Incorporated | Compositions and methods for detecting small rnas, and uses thereof |
| CN102099488B (zh) * | 2009-01-05 | 2013-04-03 | 汪小龙 | 利用聚合酶-内切酶链式反应扩增寡核苷酸和小rna的方法 |
| JP6126381B2 (ja) * | 2010-12-10 | 2017-05-10 | 国立大学法人東京工業大学 | 標的核酸の検出方法及びキット |
| CN102399871B (zh) * | 2011-10-24 | 2014-04-16 | 中国科学院广州生物医药与健康研究院 | 耐热等温核酸检测试剂及其试剂盒和检测方法 |
| RU2732589C2 (ru) * | 2012-04-09 | 2020-09-21 | Инвайролоджикс Инк. | Композиции и способы для количественного определения последовательности нуклеиновой кислоты в образце |
| EP2722399A1 (en) | 2012-10-18 | 2014-04-23 | Roche Diagniostics GmbH | Method for preventing high molecular weight products during amplification |
| ES2754251T3 (es) | 2014-01-15 | 2020-04-16 | Abbott Lab | Secuencia cubierta de conversión de ADN y métodos de detección |
| CN103789435B (zh) | 2014-01-29 | 2015-08-26 | 西安交通大学 | 一种基于级联恒温扩增的miRNA荧光检测试剂盒及方法 |
| US10208333B2 (en) | 2014-10-14 | 2019-02-19 | Abbott Laboratories | Sequence conversion and signal amplifier DNA having locked nucleic acids and detection methods using same |
-
2015
- 2015-10-13 US US14/882,124 patent/US10208333B2/en active Active
- 2015-10-13 ES ES15850599T patent/ES2759339T3/es active Active
- 2015-10-13 JP JP2017519832A patent/JP6773651B2/ja active Active
- 2015-10-13 US US14/882,109 patent/US10316353B2/en active Active
- 2015-10-13 EP EP15850599.0A patent/EP3207160B1/en active Active
- 2015-10-13 WO PCT/IB2015/002145 patent/WO2016059474A2/en not_active Ceased
- 2015-10-13 EP EP15850183.3A patent/EP3207159B1/en active Active
- 2015-10-13 CN CN201580056019.0A patent/CN107109473B/zh active Active
- 2015-10-13 CN CN201580056020.3A patent/CN107075585B/zh active Active
- 2015-10-13 ES ES15850183T patent/ES2759337T3/es active Active
- 2015-10-13 JP JP2017519860A patent/JP6896620B2/ja active Active
- 2015-10-13 WO PCT/IB2015/002141 patent/WO2016059473A2/en not_active Ceased
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