JP6896620B2 - ロックされた核酸を有する配列変換およびシグナル増幅ｄｎａならびにそれを用いた検出方法 - Google Patents

ロックされた核酸を有する配列変換およびシグナル増幅ｄｎａならびにそれを用いた検出方法 Download PDF

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JP6896620B2
JP6896620B2 JP2017519860A JP2017519860A JP6896620B2 JP 6896620 B2 JP6896620 B2 JP 6896620B2 JP 2017519860 A JP2017519860 A JP 2017519860A JP 2017519860 A JP2017519860 A JP 2017519860A JP 6896620 B2 JP6896620 B2 JP 6896620B2
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sequence
dna
nucleic acid
oligonucleotide
positions
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JP2017530715A5 (enExample
JP2017530715A (ja
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健 小宮
健 小宮
誠 小森
誠 小森
吉村　徹
徹 吉村
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Abbott Laboratories
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions

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  • Organic Chemistry (AREA)
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  • Engineering & Computer Science (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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JP2017519860A 2014-10-14 2015-10-13 ロックされた核酸を有する配列変換およびシグナル増幅ｄｎａならびにそれを用いた検出方法 Active JP6896620B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462063666P 2014-10-14 2014-10-14
US62/063,666 2014-10-14
US201462098066P 2014-12-30 2014-12-30
US62/098,066 2014-12-30
PCT/IB2015/002141 WO2016059473A2 (en) 2014-10-14 2015-10-13 Sequence conversion and signal amplifier dna having locked nucleic acids and detection methods using same

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JP2017530715A JP2017530715A (ja) 2017-10-19
JP2017530715A5 JP2017530715A5 (enExample) 2019-01-10
JP6896620B2 true JP6896620B2 (ja) 2021-06-30

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JP2017519860A Active JP6896620B2 (ja) 2014-10-14 2015-10-13 ロックされた核酸を有する配列変換およびシグナル増幅ｄｎａならびにそれを用いた検出方法
JP2017519832A Active JP6773651B2 (ja) 2014-10-14 2015-10-13 ポリｄｎａスペーサー配列を有する配列変換およびシグナル増幅ｄｎａならびにそれらを用いた検出方法

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US (2) US10208333B2 (enExample)
EP (2) EP3207160B1 (enExample)
JP (2) JP6896620B2 (enExample)
CN (2) CN107075585B (enExample)
ES (2) ES2759339T3 (enExample)
WO (2) WO2016059474A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6126381B2 (ja) 2010-12-10 2017-05-10 国立大学法人東京工業大学 標的核酸の検出方法及びキット
WO2015114469A2 (en) 2014-01-15 2015-08-06 Abbott Japan Co., Ltd Covered sequence conversion dna and detection methods
WO2016059474A2 (en) 2014-10-14 2016-04-21 Abbott Japan Co., Ltd Sequence conversion and signal amplifier dna having poly dna spacer sequences and detection methods using same
EP3237641B1 (en) 2014-12-24 2020-04-08 Abbott Laboratories Detection method, composition and kit based on signal amplifier dna cascade reactions with target extension
GB201611469D0 (en) 2016-06-30 2016-08-17 Lumiradx Tech Ltd Improvements in or relating to nucleic acid amplification processes
GB2569965A (en) 2018-01-04 2019-07-10 Lumiradx Uk Ltd Improvements in or relating to amplification of nucleic acids
US20230220474A1 (en) * 2020-06-10 2023-07-13 Bonadea Diagnostics, Llc Sequence conversion reaction
WO2023107713A2 (en) * 2021-12-09 2023-06-15 Bonadea Diagnostics, Llc Sequence conversion reaction

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US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US5455166A (en) 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
JPH07114718A (ja) 1993-10-18 1995-05-02 Tanashin Denki Co テープレコーダの回転ヘッド装置
US5928869A (en) 1997-05-30 1999-07-27 Becton, Dickinson And Company Detection of nucleic acids by fluorescence quenching
EP2045337B1 (en) 1998-11-09 2011-08-24 Eiken Kagaku Kabushiki Kaisha Process for synthesizing nucleic acid
US6316200B1 (en) 2000-06-08 2001-11-13 Becton, Dickinson And Company Probes and methods for detection of nucleic acids
JP4128074B2 (ja) * 2000-08-23 2008-07-30 タカラバイオ株式会社 核酸の増幅方法
US20030165911A1 (en) * 2001-07-15 2003-09-04 Keck Graduate Institute Gene expression analysis using nicking agents
CA2462144C (en) 2001-09-28 2016-09-20 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Micro-rna molecules
EP1500710A4 (en) 2002-05-08 2006-10-04 Arkray Inc METHOD FOR DETECTING TARGET NUCLEIC ACID
WO2004010101A2 (en) 2002-07-18 2004-01-29 The Board Of Trustees Of The Leland Stanford Junior University Detection of chemical ligation using fluorescence quenching leaving groups
WO2004067726A2 (en) 2003-01-29 2004-08-12 Keck Graduate Institute Isothermal reactions for the amplification of oligonucleotides
WO2004067765A2 (en) 2003-01-29 2004-08-12 Keck Graduate Institute Organism fingerprinting using nicking agents
WO2004067764A2 (en) 2003-01-29 2004-08-12 Keck Graduate Institute Nucleic acid sequencing using nicking agents
US7632639B2 (en) * 2003-02-21 2009-12-15 Eisai R&D Management Co., Ltd. Signal amplification method for detecting mutated gene
CN101415838A (zh) * 2003-09-26 2009-04-22 首科安普有限公司 用滚环扩增法扩增多核苷酸
WO2006017724A1 (en) 2004-08-06 2006-02-16 Becton, Dickinson And Company Sequences and methods for detection of cytomegalovirus
WO2008001376A2 (en) 2006-06-28 2008-01-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem Detection of analytes in a medium
US9689031B2 (en) 2007-07-14 2017-06-27 Ionian Technologies, Inc. Nicking and extension amplification reaction for the exponential amplification of nucleic acids
WO2010068473A1 (en) 2008-11-25 2010-06-17 Gen-Probe Incorporated Compositions and methods for detecting small rnas, and uses thereof
US20120028253A1 (en) * 2009-01-05 2012-02-02 Xiaolong Wang Method for amplifying oligonucleotide and small rna by using polymerase-endonuclease chain reaction
JP6126381B2 (ja) * 2010-12-10 2017-05-10 国立大学法人東京工業大学 標的核酸の検出方法及びキット
CN102399871B (zh) * 2011-10-24 2014-04-16 中国科学院广州生物医药与健康研究院 耐热等温核酸检测试剂及其试剂盒和检测方法
EP3587587B1 (en) * 2012-04-09 2024-11-06 Envirologix Inc. Compositions and methods for quantifying a nucleic acid sequence in a sample
EP2722399A1 (en) 2012-10-18 2014-04-23 Roche Diagniostics GmbH Method for preventing high molecular weight products during amplification
WO2015114469A2 (en) 2014-01-15 2015-08-06 Abbott Japan Co., Ltd Covered sequence conversion dna and detection methods
CN103789435B (zh) 2014-01-29 2015-08-26 西安交通大学 一种基于级联恒温扩增的miRNA荧光检测试剂盒及方法
WO2016059474A2 (en) 2014-10-14 2016-04-21 Abbott Japan Co., Ltd Sequence conversion and signal amplifier dna having poly dna spacer sequences and detection methods using same

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Publication number Publication date
EP3207159A2 (en) 2017-08-23
ES2759339T3 (es) 2020-05-08
EP3207159A4 (en) 2018-05-30
ES2759337T3 (es) 2020-05-08
WO2016059473A2 (en) 2016-04-21
US10208333B2 (en) 2019-02-19
US10316353B2 (en) 2019-06-11
CN107075585B (zh) 2021-07-20
CN107075585A (zh) 2017-08-18
EP3207160B1 (en) 2019-11-20
CN107075585A8 (zh) 2019-02-15
JP6773651B2 (ja) 2020-10-21
JP2017530715A (ja) 2017-10-19
WO2016059474A3 (en) 2016-06-09
US20160102345A1 (en) 2016-04-14
JP2017532044A (ja) 2017-11-02
WO2016059474A2 (en) 2016-04-21
EP3207159B1 (en) 2019-11-20
US20160102339A1 (en) 2016-04-14
EP3207160A4 (en) 2018-05-23
CN107109473B (zh) 2020-11-06
CN107109473A (zh) 2017-08-29
EP3207160A2 (en) 2017-08-23
WO2016059473A3 (en) 2016-06-23

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