JP2017514467A5 - - Google Patents
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- Publication number
- JP2017514467A5 JP2017514467A5 JP2016562759A JP2016562759A JP2017514467A5 JP 2017514467 A5 JP2017514467 A5 JP 2017514467A5 JP 2016562759 A JP2016562759 A JP 2016562759A JP 2016562759 A JP2016562759 A JP 2016562759A JP 2017514467 A5 JP2017514467 A5 JP 2017514467A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- caliper
- target
- splint
- bound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461982914P | 2014-04-23 | 2014-04-23 | |
| US61/982,914 | 2014-04-23 | ||
| PCT/US2015/027290 WO2015164602A2 (en) | 2014-04-23 | 2015-04-23 | High-throughput structure determination using nucleic acid calipers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017514467A JP2017514467A (ja) | 2017-06-08 |
| JP2017514467A5 true JP2017514467A5 (enExample) | 2018-06-07 |
Family
ID=54333422
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016562759A Ceased JP2017514467A (ja) | 2014-04-23 | 2015-04-23 | 核酸キャリパーを用いた高スループット構造決定 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9897597B2 (enExample) |
| EP (2) | EP3594363A1 (enExample) |
| JP (1) | JP2017514467A (enExample) |
| CN (1) | CN106661616A (enExample) |
| WO (1) | WO2015164602A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8491454B2 (en) | 2008-12-02 | 2013-07-23 | President And Fellows Of Harvard College | Spinning force apparatus |
| CN106661616A (zh) | 2014-04-23 | 2017-05-10 | 儿童医学中心公司 | 使用核酸卡尺的高通量结构测定 |
| US11198900B2 (en) | 2014-12-06 | 2021-12-14 | Children's Medical Center Corporation | Nucleic acid-based linkers for detecting and measuring interactions |
| KR20160100175A (ko) * | 2015-02-13 | 2016-08-23 | 주식회사 삼홍사 | 높낮이 조절이 가능한 책상 |
| US11396650B2 (en) | 2015-06-02 | 2022-07-26 | Children's Medical Center Corporation | Nucleic acid complexes for screening barcoded compounds |
| US12077807B2 (en) | 2015-06-27 | 2024-09-03 | The Research Foundation For The State University Of New York | Compositions and methods for analyte detection using nanoswitches |
| WO2017139409A1 (en) | 2016-02-09 | 2017-08-17 | Children's Medical Center Corporation | Method for detection of analytes via polymer complexes |
| WO2017147398A1 (en) | 2016-02-25 | 2017-08-31 | Children's Medical Center Corporation | Spinning apparatus for measurement of characteristics relating to molecules |
| WO2017151062A1 (en) * | 2016-03-03 | 2017-09-08 | National University Of Singapore | A method of determining a presence of interaction between a substance molecule and a substrate molecule |
| WO2017165647A1 (en) | 2016-03-23 | 2017-09-28 | Children's Medical Center Corporation | Rapid and sensitive detection and quantification of analytes in complex samples using polymer-based methods |
| WO2017216270A1 (de) | 2016-06-15 | 2017-12-21 | Grabmayr Heinrich | Einzelmolekülnachweis bzw. -quantifizierung durch dna-nanotechnologie |
| TWM549567U (zh) * | 2016-12-30 | 2017-10-01 | Kelly Int Corp | 薄型升降台 |
| US11591636B2 (en) | 2017-11-20 | 2023-02-28 | Children's Medical Center Corporation | Force-controlled nanoswitch assays for single-molecule detection in complex biological fluids |
| CN109961144A (zh) * | 2019-03-08 | 2019-07-02 | 华北电力大学 | 一种基于dna核酶的dna分子逻辑门 |
| WO2021174071A1 (en) | 2020-02-29 | 2021-09-02 | President And Fellows Of Harvard College | Nanoswitch caliper trains for high-throughput, high-resolution structural analysis of biomolecules |
| CN112998395A (zh) * | 2021-04-22 | 2021-06-22 | 宁波翘楚智能设备科技有限公司 | 可升降桌上桌 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4469863A (en) | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
| US5023243A (en) | 1981-10-23 | 1991-06-11 | Molecular Biosystems, Inc. | Oligonucleotide therapeutic agent and method of making same |
| EP0092574B1 (en) | 1981-10-23 | 1992-04-29 | Molecular Biosystems, Inc. | Oligonucleotide therapeutic agent and methods of making same |
| CA2239683A1 (en) * | 1995-12-22 | 1997-07-03 | Dade Behring Marburg Gmbh | Homogeneous amplification and detection of nucleic acids |
| US20040054162A1 (en) * | 2001-10-30 | 2004-03-18 | Hanna Michelle M. | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
| WO2005092038A2 (en) * | 2004-03-22 | 2005-10-06 | The Johns Hopkins University | Methods for the detection of nucleic acid differences |
| US7842793B2 (en) | 2005-06-14 | 2010-11-30 | The California Institute Of Technology | Methods of making nucleic acid nanostructures |
| US7745594B2 (en) | 2005-07-21 | 2010-06-29 | California Institute Of Technology | Nucleic acid-based logic circuits |
| JP5745842B2 (ja) * | 2007-06-19 | 2015-07-08 | ストラトス ゲノミクス インコーポレイテッド | 拡張によるハイスループット核酸配列決定 |
| US9102520B2 (en) | 2008-08-13 | 2015-08-11 | California Institute Of Technology | Nanocomposite structures and related methods and systems |
| US8491454B2 (en) | 2008-12-02 | 2013-07-23 | President And Fellows Of Harvard College | Spinning force apparatus |
| US9599591B2 (en) * | 2009-03-06 | 2017-03-21 | California Institute Of Technology | Low cost, portable sensor for molecular assays |
| US9845492B2 (en) * | 2009-12-21 | 2017-12-19 | Seegene, Inc. | TSG primer target detection |
| US20120238738A1 (en) | 2010-07-19 | 2012-09-20 | New England Biolabs, Inc. | Oligonucleotide Adapters: Compositions and Methods of Use |
| CA2818556A1 (en) * | 2010-11-24 | 2012-05-31 | The Regents Of The University Of California | Nucleotide-based probes and methods for the detection and quantification of macromolecules and other analytes |
| US20130005049A1 (en) * | 2011-06-30 | 2013-01-03 | Kent State University | Devices and methods for detecting single nucleotide polymorphisms |
| US9428799B2 (en) * | 2011-07-25 | 2016-08-30 | Bioinventors & Entrepreneurs Network Llc | Method for determining an allele profile of nucleic acid |
| CN103889998A (zh) | 2011-08-05 | 2014-06-25 | 哈佛学院院长等 | 涉及核酸纳米和微米技术的组合物和方法 |
| EP2769213A4 (en) * | 2011-10-18 | 2015-03-18 | Twistnostics Llc | DETECTORS AND METHOD FOR DETECTING A TARGET ANALYT |
| JP6430253B2 (ja) * | 2011-11-05 | 2018-11-28 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 相互作用を検出および測定するための核酸ベースのリンカー |
| EP3321378B1 (en) * | 2012-02-27 | 2021-11-10 | Becton, Dickinson and Company | Compositions for molecular counting |
| US10604543B2 (en) | 2012-07-24 | 2020-03-31 | President And Fellows Of Harvard College | Self-assembly of nucleic acid nanostructures |
| CN106661616A (zh) | 2014-04-23 | 2017-05-10 | 儿童医学中心公司 | 使用核酸卡尺的高通量结构测定 |
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2015
- 2015-04-23 CN CN201580027026.8A patent/CN106661616A/zh active Pending
- 2015-04-23 JP JP2016562759A patent/JP2017514467A/ja not_active Ceased
- 2015-04-23 EP EP19195115.1A patent/EP3594363A1/en not_active Withdrawn
- 2015-04-23 WO PCT/US2015/027290 patent/WO2015164602A2/en not_active Ceased
- 2015-04-23 EP EP15783027.4A patent/EP3134550B1/en active Active
- 2015-04-23 US US15/305,399 patent/US9897597B2/en active Active
-
2018
- 2018-01-05 US US15/862,947 patent/US10914733B2/en active Active