JP2017514467A5 - - Google Patents
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- Publication number
- JP2017514467A5 JP2017514467A5 JP2016562759A JP2016562759A JP2017514467A5 JP 2017514467 A5 JP2017514467 A5 JP 2017514467A5 JP 2016562759 A JP2016562759 A JP 2016562759A JP 2016562759 A JP2016562759 A JP 2016562759A JP 2017514467 A5 JP2017514467 A5 JP 2017514467A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- caliper
- target
- splint
- bound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 108020004707 nucleic acids Proteins 0.000 claims 55
- 150000007523 nucleic acids Chemical class 0.000 claims 55
- 102000039446 nucleic acids Human genes 0.000 claims 55
- 230000000295 complement effect Effects 0.000 claims 8
- 101100478969 Oryza sativa subsp. japonica SUS2 gene Proteins 0.000 claims 7
- 101100004663 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) BRR2 gene Proteins 0.000 claims 7
- 101100504519 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GLE1 gene Proteins 0.000 claims 7
- 238000000034 method Methods 0.000 claims 7
- 101100150875 Oryza sativa subsp. japonica SUS1 gene Proteins 0.000 claims 6
- 108091034117 Oligonucleotide Proteins 0.000 claims 5
- 101100364280 Oryza sativa subsp. japonica RSS3 gene Proteins 0.000 claims 5
- 101100478972 Oryza sativa subsp. japonica SUS3 gene Proteins 0.000 claims 5
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 4
- 239000011324 bead Substances 0.000 claims 3
- MXHRCPNRJAMMIM-SHYZEUOFSA-N 2'-deoxyuridine Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C=C1 MXHRCPNRJAMMIM-SHYZEUOFSA-N 0.000 claims 2
- MXHRCPNRJAMMIM-UHFFFAOYSA-N desoxyuridine Natural products C1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 MXHRCPNRJAMMIM-UHFFFAOYSA-N 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 108060002716 Exonuclease Proteins 0.000 claims 1
- 102000006943 Uracil-DNA Glycosidase Human genes 0.000 claims 1
- 108010072685 Uracil-DNA Glycosidase Proteins 0.000 claims 1
- 238000003491 array Methods 0.000 claims 1
- 238000004132 cross linking Methods 0.000 claims 1
- 102000013165 exonuclease Human genes 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461982914P | 2014-04-23 | 2014-04-23 | |
| US61/982,914 | 2014-04-23 | ||
| PCT/US2015/027290 WO2015164602A2 (en) | 2014-04-23 | 2015-04-23 | High-throughput structure determination using nucleic acid calipers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017514467A JP2017514467A (ja) | 2017-06-08 |
| JP2017514467A5 true JP2017514467A5 (enExample) | 2018-06-07 |
Family
ID=54333422
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016562759A Ceased JP2017514467A (ja) | 2014-04-23 | 2015-04-23 | 核酸キャリパーを用いた高スループット構造決定 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9897597B2 (enExample) |
| EP (2) | EP3134550B1 (enExample) |
| JP (1) | JP2017514467A (enExample) |
| CN (1) | CN106661616A (enExample) |
| WO (1) | WO2015164602A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8491454B2 (en) | 2008-12-02 | 2013-07-23 | President And Fellows Of Harvard College | Spinning force apparatus |
| WO2015164602A2 (en) | 2014-04-23 | 2015-10-29 | Children's Medical Center Corporation | High-throughput structure determination using nucleic acid calipers |
| WO2016089588A1 (en) | 2014-12-06 | 2016-06-09 | Children's Medical Center Corporation | Nucleic acid-based linkers for detecting and measuring interactions |
| KR20160100175A (ko) * | 2015-02-13 | 2016-08-23 | 주식회사 삼홍사 | 높낮이 조절이 가능한 책상 |
| WO2016196824A1 (en) | 2015-06-02 | 2016-12-08 | Children's Medical Center Corporation | Nucleic acid complexes for screening barcoded compounds |
| WO2017003950A2 (en) | 2015-06-27 | 2017-01-05 | Children's Medical Center Corporation | Compositions and methods for analyte detection using nanoswitches |
| US11713483B2 (en) | 2016-02-09 | 2023-08-01 | Children's Medical Center Corporation | Method for detection of analytes via polymer complexes |
| WO2017147398A1 (en) | 2016-02-25 | 2017-08-31 | Children's Medical Center Corporation | Spinning apparatus for measurement of characteristics relating to molecules |
| WO2017151062A1 (en) * | 2016-03-03 | 2017-09-08 | National University Of Singapore | A method of determining a presence of interaction between a substance molecule and a substrate molecule |
| US12123869B2 (en) | 2016-03-23 | 2024-10-22 | Children's Medical Center Corporation | Rapid and sensitive detection and quantification of analytes in complex samples using polymer-based methods |
| CN109563539A (zh) | 2016-06-15 | 2019-04-02 | 慕尼黑路德维希马克西米利安斯大学 | 使用dna纳米技术的单分子检测或定量 |
| TWM549567U (zh) * | 2016-12-30 | 2017-10-01 | Kelly Int Corp | 薄型升降台 |
| US11591636B2 (en) | 2017-11-20 | 2023-02-28 | Children's Medical Center Corporation | Force-controlled nanoswitch assays for single-molecule detection in complex biological fluids |
| CN109961144A (zh) * | 2019-03-08 | 2019-07-02 | 华北电力大学 | 一种基于dna核酶的dna分子逻辑门 |
| CN112998395A (zh) * | 2021-04-22 | 2021-06-22 | 宁波翘楚智能设备科技有限公司 | 可升降桌上桌 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4469863A (en) | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
| US5023243A (en) | 1981-10-23 | 1991-06-11 | Molecular Biosystems, Inc. | Oligonucleotide therapeutic agent and method of making same |
| DE3280400D1 (de) | 1981-10-23 | 1992-06-04 | Molecular Biosystems Inc | Oligonukleotides heilmittel und dessen herstellungsverfahren. |
| WO1997023647A1 (en) * | 1995-12-22 | 1997-07-03 | Behringwerke Aktiengesellschaft | Homogeneous amplification and detection of nucleic acids |
| US20040054162A1 (en) * | 2001-10-30 | 2004-03-18 | Hanna Michelle M. | Molecular detection systems utilizing reiterative oligonucleotide synthesis |
| WO2005092038A2 (en) * | 2004-03-22 | 2005-10-06 | The Johns Hopkins University | Methods for the detection of nucleic acid differences |
| US7842793B2 (en) | 2005-06-14 | 2010-11-30 | The California Institute Of Technology | Methods of making nucleic acid nanostructures |
| US7745594B2 (en) | 2005-07-21 | 2010-06-29 | California Institute Of Technology | Nucleic acid-based logic circuits |
| CN102083998B (zh) * | 2007-06-19 | 2016-08-03 | 斯特拉托斯基因公司 | 通过展开进行高通量核酸测序 |
| US9102520B2 (en) | 2008-08-13 | 2015-08-11 | California Institute Of Technology | Nanocomposite structures and related methods and systems |
| US8491454B2 (en) | 2008-12-02 | 2013-07-23 | President And Fellows Of Harvard College | Spinning force apparatus |
| US9599591B2 (en) * | 2009-03-06 | 2017-03-21 | California Institute Of Technology | Low cost, portable sensor for molecular assays |
| AU2010336137B2 (en) * | 2009-12-21 | 2015-08-06 | Seegene, Inc. | TSG primer target detection |
| US20120238738A1 (en) | 2010-07-19 | 2012-09-20 | New England Biolabs, Inc. | Oligonucleotide Adapters: Compositions and Methods of Use |
| CA2818556A1 (en) * | 2010-11-24 | 2012-05-31 | The Regents Of The University Of California | Nucleotide-based probes and methods for the detection and quantification of macromolecules and other analytes |
| US20130005049A1 (en) * | 2011-06-30 | 2013-01-03 | Kent State University | Devices and methods for detecting single nucleotide polymorphisms |
| US9428799B2 (en) * | 2011-07-25 | 2016-08-30 | Bioinventors & Entrepreneurs Network Llc | Method for determining an allele profile of nucleic acid |
| US9796749B2 (en) | 2011-08-05 | 2017-10-24 | President And Fellows Of Harvard College | Compositions and methods relating to nucleic acid nano- and micro-technology |
| WO2013059044A1 (en) * | 2011-10-18 | 2013-04-25 | Celedon Alfredo Andres | Detection units and methods for detecting a target analyte |
| US9914958B2 (en) * | 2011-11-05 | 2018-03-13 | President And Fellows Of Harvard College | Nucleic acid-based linkers for detecting and measuring interactions |
| JP6375230B2 (ja) * | 2012-02-27 | 2018-08-15 | セルラー リサーチ， インコーポレイテッド | 分子計数のための組成物およびキット |
| US10604543B2 (en) | 2012-07-24 | 2020-03-31 | President And Fellows Of Harvard College | Self-assembly of nucleic acid nanostructures |
| WO2015164602A2 (en) | 2014-04-23 | 2015-10-29 | Children's Medical Center Corporation | High-throughput structure determination using nucleic acid calipers |
-
2015
- 2015-04-23 WO PCT/US2015/027290 patent/WO2015164602A2/en not_active Ceased
- 2015-04-23 EP EP15783027.4A patent/EP3134550B1/en active Active
- 2015-04-23 CN CN201580027026.8A patent/CN106661616A/zh active Pending
- 2015-04-23 US US15/305,399 patent/US9897597B2/en active Active
- 2015-04-23 JP JP2016562759A patent/JP2017514467A/ja not_active Ceased
- 2015-04-23 EP EP19195115.1A patent/EP3594363A1/en not_active Withdrawn
-
2018
- 2018-01-05 US US15/862,947 patent/US10914733B2/en active Active
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