JP2017533710A5 - - Google Patents
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- JP2017533710A5 JP2017533710A5 JP2017524429A JP2017524429A JP2017533710A5 JP 2017533710 A5 JP2017533710 A5 JP 2017533710A5 JP 2017524429 A JP2017524429 A JP 2017524429A JP 2017524429 A JP2017524429 A JP 2017524429A JP 2017533710 A5 JP2017533710 A5 JP 2017533710A5
- Authority
- JP
- Japan
- Prior art keywords
- capture
- primer
- well
- layer
- primer pair
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 108091033319 polynucleotide Proteins 0.000 claims 36
- 102000040430 polynucleotide Human genes 0.000 claims 36
- 239000002157 polynucleotide Substances 0.000 claims 36
- 239000000758 substrate Substances 0.000 claims 25
- 239000002773 nucleotide Substances 0.000 claims 20
- 125000003729 nucleotide group Chemical group 0.000 claims 20
- 238000000034 method Methods 0.000 claims 19
- 238000002493 microarray Methods 0.000 claims 13
- 102000039446 nucleic acids Human genes 0.000 claims 12
- 108020004707 nucleic acids Proteins 0.000 claims 12
- 150000007523 nucleic acids Chemical class 0.000 claims 12
- 230000000295 complement effect Effects 0.000 claims 11
- 108091093088 Amplicon Proteins 0.000 claims 10
- 239000011248 coating agent Substances 0.000 claims 9
- 238000000576 coating method Methods 0.000 claims 9
- 238000000151 deposition Methods 0.000 claims 9
- 229920000642 polymer Polymers 0.000 claims 9
- 230000003321 amplification Effects 0.000 claims 3
- 238000003199 nucleic acid amplification method Methods 0.000 claims 3
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 claims 3
- -1 5-azidoacetamidylpentyl Chemical group 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 1
- 108091000080 Phosphotransferase Proteins 0.000 claims 1
- 230000003213 activating effect Effects 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 230000003190 augmentative effect Effects 0.000 claims 1
- 230000007717 exclusion Effects 0.000 claims 1
- 102000020233 phosphotransferase Human genes 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021213441A JP7323598B2 (ja) | 2014-11-11 | 2021-12-27 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462078346P | 2014-11-11 | 2014-11-11 | |
| US62/078,346 | 2014-11-11 | ||
| US201462096464P | 2014-12-23 | 2014-12-23 | |
| US62/096,464 | 2014-12-23 | ||
| PCT/EP2015/076353 WO2016075204A1 (en) | 2014-11-11 | 2015-11-11 | Methods and arrays for producing and sequencing monoclonal clusters of nucleic acid |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021213441A Division JP7323598B2 (ja) | 2014-11-11 | 2021-12-27 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017533710A JP2017533710A (ja) | 2017-11-16 |
| JP2017533710A5 true JP2017533710A5 (enExample) | 2018-12-20 |
| JP7032930B2 JP7032930B2 (ja) | 2022-03-09 |
Family
ID=54540094
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017524429A Active JP7032930B2 (ja) | 2014-11-11 | 2015-11-11 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
| JP2021213441A Active JP7323598B2 (ja) | 2014-11-11 | 2021-12-27 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021213441A Active JP7323598B2 (ja) | 2014-11-11 | 2021-12-27 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US10619204B2 (enExample) |
| EP (1) | EP3218511B1 (enExample) |
| JP (2) | JP7032930B2 (enExample) |
| KR (1) | KR102590448B1 (enExample) |
| CN (1) | CN107208019B (enExample) |
| AU (1) | AU2015345125B2 (enExample) |
| DK (1) | DK3218511T3 (enExample) |
| ES (1) | ES2802405T3 (enExample) |
| MY (1) | MY182476A (enExample) |
| PL (1) | PL3218511T3 (enExample) |
| PT (1) | PT3218511T (enExample) |
| SG (2) | SG10202004350TA (enExample) |
| WO (1) | WO2016075204A1 (enExample) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3246416T3 (pl) | 2011-04-15 | 2024-09-30 | The Johns Hopkins University | Bezpieczny system sekwencjonowania |
| CN109457030B (zh) | 2012-10-29 | 2022-02-18 | 约翰·霍普金斯大学 | 卵巢和子宫内膜癌的帕帕尼科拉乌测试 |
| KR20160039229A (ko) | 2013-07-30 | 2016-04-08 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 정량적 dna-기반 영상화 및 초해상도 영상화 |
| US10415083B2 (en) | 2013-10-28 | 2019-09-17 | The Translational Genomics Research Institute | Long insert-based whole genome sequencing |
| DK3218511T3 (da) | 2014-11-11 | 2020-07-20 | Illumina Cambridge Ltd | Fremgangsmåder og arrays til frembringelse og sekventering af monoklonale klynger af nukleinsyre |
| US20180057873A1 (en) * | 2015-04-17 | 2018-03-01 | Centrillion Technology Holdings Corporation | Methods for performing spatial profiling of biological materials |
| KR102557419B1 (ko) * | 2015-08-07 | 2023-07-19 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 단백질-단백질 상호작용의 초해상도 영상화 |
| US11286531B2 (en) | 2015-08-11 | 2022-03-29 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| JP2017209051A (ja) * | 2016-05-25 | 2017-11-30 | 株式会社ニコン | 標的生体分子の検出方法、標的生体分子検出用基板、及び標的生体分子検出装置 |
| CN110325651B (zh) * | 2016-12-22 | 2024-03-15 | 伊鲁米那股份有限公司 | 具有质量控制示踪剂的阵列 |
| GB201704754D0 (en) * | 2017-01-05 | 2017-05-10 | Illumina Inc | Kinetic exclusion amplification of nucleic acid libraries |
| NL2019044B1 (en) * | 2017-05-11 | 2018-11-15 | Illumina Inc | Protective surface coatings for flow cells |
| WO2018218136A1 (en) * | 2017-05-25 | 2018-11-29 | Integrated Dna Technologies, Inc. | Reverse complement adapters for the mitigation of umi hopping |
| US11001885B2 (en) | 2017-06-13 | 2021-05-11 | Personal Genomics Taiwan, Inc. | Apparatus for single molecular sequencing and method of sequencing nucleic acid molecules |
| EP3665308A1 (en) | 2017-08-07 | 2020-06-17 | The Johns Hopkins University | Methods and materials for assessing and treating cancer |
| CN107523640A (zh) * | 2017-10-12 | 2017-12-29 | 厦门燕旭安生物科技有限公司 | 一种ctDNA精准测序的扩增子文库构建方法 |
| CA3066535C (en) * | 2017-12-21 | 2022-08-02 | Illumina, Inc. | Flow cells with hydrogel coating |
| WO2019228995A1 (en) * | 2018-05-28 | 2019-12-05 | F. Hoffmann-La Roche Ag | Enzymatic enrichment of dna-pore-polymerase complexes |
| JP7437161B2 (ja) * | 2018-06-29 | 2024-02-22 | イラミーナ インコーポレーテッド | フローセル |
| TWI730352B (zh) | 2018-08-06 | 2021-06-11 | 英商伊路米納劍橋有限公司 | 流體槽與定序系統及製備用於其之基板的方法 |
| US20200149095A1 (en) * | 2018-11-14 | 2020-05-14 | Element Biosciences, Inc. | Low binding supports for improved solid-phase dna hybridization and amplification |
| SG11202012762WA (en) * | 2018-12-05 | 2021-01-28 | Illumina Cambridge Ltd | Methods and compositions for cluster generation by bridge amplification |
| KR102872035B1 (ko) | 2018-12-18 | 2025-10-16 | 일루미나 케임브리지 리미티드 | 단일 표면 프라이머를 사용하는 페어드 엔드 서열분석을 위한 방법 및 조성물 |
| WO2020132103A1 (en) * | 2018-12-19 | 2020-06-25 | Illumina, Inc. | Methods for improving polynucleotide cluster clonality priority |
| TWI857000B (zh) | 2019-01-29 | 2024-10-01 | 美商伊路米納有限公司 | 流體槽以及將複合物引入至流體槽之方法 |
| TWI873119B (zh) | 2019-01-29 | 2025-02-21 | 美商伊路米納有限公司 | 流通槽及製備其之方法 |
| TWI857001B (zh) | 2019-01-29 | 2024-10-01 | 美商伊路米納有限公司 | 定序套組 |
| US20210147833A1 (en) * | 2019-05-31 | 2021-05-20 | Illumina, Inc. | Systems and methods for information storage and retrieval using flow cells |
| US20220230706A1 (en) | 2019-05-31 | 2022-07-21 | Nec Corporation | Information processing apparatus, information processing method and information processing program |
| TW202120693A (zh) * | 2019-08-21 | 2021-06-01 | 美商伊路米納有限公司 | 偵測核苷酸之聚合酶併入的方法 |
| CA3135280A1 (en) * | 2019-12-16 | 2021-06-24 | Illumina, Inc. | Kits and flow cells |
| CA3145322A1 (en) * | 2019-12-20 | 2021-06-24 | Illumina, Inc. | Flow cells |
| JP7722934B2 (ja) * | 2019-12-23 | 2025-08-13 | イルミナ インコーポレイテッド | 鋳型ポリヌクレオチド結合のための単一部位を有するナノ粒子 |
| BR112022015909A2 (pt) | 2020-02-14 | 2022-10-04 | Univ Johns Hopkins | Métodos e materiais para avaliação de ácidos nucleicos |
| EP4107286A4 (en) * | 2020-02-19 | 2024-04-24 | Sequencing Health, Inc. | METHODS AND SYSTEMS FOR PROCESSING NUCLEIC ACIDS |
| CA3145539A1 (en) * | 2020-02-26 | 2021-09-02 | Illumina, Inc. | Kits for genotyping |
| AU2021230282A1 (en) * | 2020-03-03 | 2022-09-22 | Pacific Biosciences Of California, Inc. | Methods and compositions for sequencing double stranded nucleic acids |
| US20220251626A1 (en) * | 2020-03-09 | 2022-08-11 | Illumina, Inc. | Improvements in nucleic acid sequencing |
| EP4150065A2 (en) | 2020-05-12 | 2023-03-22 | Illumina Inc | Generating nucleic acids with modified bases using recombinant terminal deoxynucleotidyl transferase |
| BR112022026860A2 (pt) * | 2020-09-14 | 2023-04-11 | Illumina Inc | Composições e métodos para amplificar polinucleotídeos |
| CN115916393A (zh) * | 2020-09-29 | 2023-04-04 | 伊鲁米纳公司 | 流通池及其制备方法 |
| CA3182301A1 (en) * | 2020-09-29 | 2022-04-07 | Brinda Kodira Cariappa | Methods for making flow cells |
| AU2021396259A1 (en) * | 2020-12-10 | 2023-01-05 | Illumina Cambridge Limited | Image sensor structures and related methods |
| US20220195516A1 (en) * | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Methods, systems and compositions for nucleic acid sequencing |
| WO2022192671A1 (en) * | 2021-03-12 | 2022-09-15 | Singular Genomics Systems, Inc. | Nanoarrays and methods of use thereof |
| US11884977B2 (en) | 2021-03-12 | 2024-01-30 | Singular Genomics Systems, Inc. | Nanoarrays and methods of use thereof |
| BR112023022509A2 (pt) * | 2021-04-30 | 2024-01-02 | Illumina Cambridge Ltd | Célula de fluxo e métodos |
| EP4337786A1 (en) * | 2021-05-10 | 2024-03-20 | Pacific Biosciences of California, Inc. | Single-molecule seeding and amplification on a surface |
| WO2024006625A1 (en) * | 2022-06-27 | 2024-01-04 | Somalogic Operating Co., Inc. | Monoclonal polony generation using nucleic acid supramolecular structures |
| WO2024006816A1 (en) * | 2022-06-29 | 2024-01-04 | 10X Genomics, Inc. | Compositions and methods for oligonucleotide inversion on arrays |
| CN116024320A (zh) * | 2022-07-13 | 2023-04-28 | 上海翔琼生物技术有限公司 | 一种用于检测核酸的荧光定量pcr方法 |
| WO2024057089A1 (en) * | 2022-09-09 | 2024-03-21 | Todx Inc. | Device for parallel detection and quantification of nucleic acid based markers |
| CN119677869A (zh) * | 2022-09-16 | 2025-03-21 | 伊路米纳有限公司 | 具有多核苷酸结合位点的纳米颗粒及其制备方法 |
| WO2024256580A1 (en) * | 2023-06-14 | 2024-12-19 | Illumina, Inc. | Concurrent sequencing with spatially separated rings |
| WO2025062001A1 (en) * | 2023-09-20 | 2025-03-27 | Illumina, Inc. | Optimised nucleic acid sequencing |
| US20250188529A1 (en) | 2023-12-12 | 2025-06-12 | Illumina, Inc. | Capturing and amplifying polynucleotides using molecules and particles |
| US20250207193A1 (en) * | 2023-12-22 | 2025-06-26 | Illumina, Inc. | Reusable flow cells and methods of using them for nucleic acid sequencing |
| CN117778578B (zh) * | 2023-12-29 | 2024-10-15 | 深圳海普洛斯医学检验实验室 | 一种基于高通量测序检测目标基因甲基化程度的引物组合物及其应用 |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0450060A1 (en) | 1989-10-26 | 1991-10-09 | Sri International | Dna sequencing |
| US5223414A (en) | 1990-05-07 | 1993-06-29 | Sri International | Process for nucleic acid hybridization and amplification |
| US5846719A (en) | 1994-10-13 | 1998-12-08 | Lynx Therapeutics, Inc. | Oligonucleotide tags for sorting and identification |
| US5750341A (en) | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| GB9620209D0 (en) | 1996-09-27 | 1996-11-13 | Cemu Bioteknik Ab | Method of sequencing DNA |
| GB9626815D0 (en) | 1996-12-23 | 1997-02-12 | Cemu Bioteknik Ab | Method of sequencing DNA |
| EP2327797B1 (en) | 1997-04-01 | 2015-11-25 | Illumina Cambridge Limited | Method of nucleic acid sequencing |
| US6969488B2 (en) | 1998-05-22 | 2005-11-29 | Solexa, Inc. | System and apparatus for sequential processing of analytes |
| US6274320B1 (en) | 1999-09-16 | 2001-08-14 | Curagen Corporation | Method of sequencing a nucleic acid |
| US6770441B2 (en) | 2000-02-10 | 2004-08-03 | Illumina, Inc. | Array compositions and methods of making same |
| US7001792B2 (en) | 2000-04-24 | 2006-02-21 | Eagle Research & Development, Llc | Ultra-fast nucleic acid sequencing device and a method for making and using the same |
| US20030064366A1 (en) | 2000-07-07 | 2003-04-03 | Susan Hardin | Real-time sequence determination |
| EP1354064A2 (en) | 2000-12-01 | 2003-10-22 | Visigen Biotechnologies, Inc. | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity |
| US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| US7399590B2 (en) | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| AU2003259350A1 (en) | 2002-08-23 | 2004-03-11 | Solexa Limited | Modified nucleotides for polynucleotide sequencing |
| EP1539979B1 (en) | 2002-09-20 | 2008-11-19 | New England Biolabs, Inc. | Helicase dependent amplification of nucleic acids |
| GB0321306D0 (en) | 2003-09-11 | 2003-10-15 | Solexa Ltd | Modified polymerases for improved incorporation of nucleotide analogues |
| WO2005065814A1 (en) | 2004-01-07 | 2005-07-21 | Solexa Limited | Modified molecular arrays |
| EP1790202A4 (en) | 2004-09-17 | 2013-02-20 | Pacific Biosciences California | APPARATUS AND METHOD FOR ANALYZING MOLECULES |
| WO2006064199A1 (en) | 2004-12-13 | 2006-06-22 | Solexa Limited | Improved method of nucleotide detection |
| US7682816B2 (en) * | 2005-04-07 | 2010-03-23 | 454 Life Sciences Corporation | Thin film coated microwell arrays and methods of using same |
| EP1888743B1 (en) | 2005-05-10 | 2011-08-03 | Illumina Cambridge Limited | Improved polymerases |
| GB0514936D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Preparation of templates for nucleic acid sequencing |
| US7405281B2 (en) | 2005-09-29 | 2008-07-29 | Pacific Biosciences Of California, Inc. | Fluorescent nucleotide analogs and uses therefor |
| CA2648149A1 (en) | 2006-03-31 | 2007-11-01 | Solexa, Inc. | Systems and devices for sequence by synthesis analysis |
| AU2007309504B2 (en) | 2006-10-23 | 2012-09-13 | Pacific Biosciences Of California, Inc. | Polymerase enzymes and reagents for enhanced nucleic acid sequencing |
| US8349167B2 (en) | 2006-12-14 | 2013-01-08 | Life Technologies Corporation | Methods and apparatus for detecting molecular interactions using FET arrays |
| EP2639578B1 (en) | 2006-12-14 | 2016-09-14 | Life Technologies Corporation | Apparatus for measuring analytes using large scale fet arrays |
| US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
| WO2008157640A2 (en) | 2007-06-18 | 2008-12-24 | Illumina, Inc. | Microfabrication methods for the optimal patterning of substrates |
| WO2011025477A1 (en) | 2009-08-25 | 2011-03-03 | Illumina, Inc. | Methods for selecting and amplifying polynucleotides |
| US8728764B2 (en) | 2008-10-02 | 2014-05-20 | Illumina Cambridge Limited | Nucleic acid sample enrichment for sequencing applications |
| US20100137143A1 (en) | 2008-10-22 | 2010-06-03 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
| US8951781B2 (en) | 2011-01-10 | 2015-02-10 | Illumina, Inc. | Systems, methods, and apparatuses to image a sample for biological or chemical analysis |
| US8778848B2 (en) | 2011-06-09 | 2014-07-15 | Illumina, Inc. | Patterned flow-cells useful for nucleic acid analysis |
| CA3104322C (en) | 2011-09-23 | 2023-06-13 | Illumina, Inc. | Methods and compositions for nucleic acid sequencing |
| EP3305400A3 (en) | 2011-10-28 | 2018-06-06 | Illumina, Inc. | Microarray fabrication system and method |
| CN204832037U (zh) | 2012-04-03 | 2015-12-02 | 伊鲁米那股份有限公司 | 检测设备 |
| US9012022B2 (en) | 2012-06-08 | 2015-04-21 | Illumina, Inc. | Polymer coatings |
| US8895249B2 (en) * | 2012-06-15 | 2014-11-25 | Illumina, Inc. | Kinetic exclusion amplification of nucleic acid libraries |
| US9512422B2 (en) | 2013-02-26 | 2016-12-06 | Illumina, Inc. | Gel patterned surfaces |
| EP3084523B1 (en) * | 2013-12-19 | 2019-07-03 | Illumina, Inc. | Substrates comprising nano-patterning surfaces and methods of preparing thereof |
| US9926598B2 (en) | 2014-01-16 | 2018-03-27 | Illumina, Inc. | Amplicon preparation and sequencing on solid supports |
| DK3218511T3 (da) | 2014-11-11 | 2020-07-20 | Illumina Cambridge Ltd | Fremgangsmåder og arrays til frembringelse og sekventering af monoklonale klynger af nukleinsyre |
-
2015
- 2015-11-11 DK DK15793823.4T patent/DK3218511T3/da active
- 2015-11-11 AU AU2015345125A patent/AU2015345125B2/en active Active
- 2015-11-11 SG SG10202004350TA patent/SG10202004350TA/en unknown
- 2015-11-11 PT PT157938234T patent/PT3218511T/pt unknown
- 2015-11-11 ES ES15793823T patent/ES2802405T3/es active Active
- 2015-11-11 EP EP15793823.4A patent/EP3218511B1/en active Active
- 2015-11-11 MY MYPI2017000708A patent/MY182476A/en unknown
- 2015-11-11 SG SG11201703693UA patent/SG11201703693UA/en unknown
- 2015-11-11 WO PCT/EP2015/076353 patent/WO2016075204A1/en not_active Ceased
- 2015-11-11 CN CN201580072860.9A patent/CN107208019B/zh active Active
- 2015-11-11 KR KR1020177015817A patent/KR102590448B1/ko active Active
- 2015-11-11 PL PL15793823T patent/PL3218511T3/pl unknown
- 2015-11-11 US US15/525,892 patent/US10619204B2/en active Active
- 2015-11-11 JP JP2017524429A patent/JP7032930B2/ja active Active
-
2020
- 2020-04-10 US US16/846,028 patent/US11692223B2/en active Active
-
2021
- 2021-12-27 JP JP2021213441A patent/JP7323598B2/ja active Active
-
2023
- 2023-05-18 US US18/320,122 patent/US12385092B2/en active Active
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