JP2017533710A5 - - Google Patents
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- JP2017533710A5 JP2017533710A5 JP2017524429A JP2017524429A JP2017533710A5 JP 2017533710 A5 JP2017533710 A5 JP 2017533710A5 JP 2017524429 A JP2017524429 A JP 2017524429A JP 2017524429 A JP2017524429 A JP 2017524429A JP 2017533710 A5 JP2017533710 A5 JP 2017533710A5
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- JP
- Japan
- Prior art keywords
- capture
- primer
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- layer
- primer pair
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108091033319 polynucleotide Proteins 0.000 claims 36
- 102000040430 polynucleotide Human genes 0.000 claims 36
- 239000002157 polynucleotide Substances 0.000 claims 36
- 239000000758 substrate Substances 0.000 claims 25
- 239000002773 nucleotide Substances 0.000 claims 20
- 125000003729 nucleotide group Chemical group 0.000 claims 20
- 238000000034 method Methods 0.000 claims 19
- 238000002493 microarray Methods 0.000 claims 13
- 102000039446 nucleic acids Human genes 0.000 claims 12
- 108020004707 nucleic acids Proteins 0.000 claims 12
- 150000007523 nucleic acids Chemical class 0.000 claims 12
- 230000000295 complement effect Effects 0.000 claims 11
- 108091093088 Amplicon Proteins 0.000 claims 10
- 239000011248 coating agent Substances 0.000 claims 9
- 238000000576 coating method Methods 0.000 claims 9
- 238000000151 deposition Methods 0.000 claims 9
- 229920000642 polymer Polymers 0.000 claims 9
- 230000003321 amplification Effects 0.000 claims 3
- 238000003199 nucleic acid amplification method Methods 0.000 claims 3
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 claims 3
- -1 5-azidoacetamidylpentyl Chemical group 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 1
- 108091000080 Phosphotransferase Proteins 0.000 claims 1
- 230000003213 activating effect Effects 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 230000003190 augmentative effect Effects 0.000 claims 1
- 230000007717 exclusion Effects 0.000 claims 1
- 102000020233 phosphotransferase Human genes 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021213441A JP7323598B2 (ja) | 2014-11-11 | 2021-12-27 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462078346P | 2014-11-11 | 2014-11-11 | |
| US62/078,346 | 2014-11-11 | ||
| US201462096464P | 2014-12-23 | 2014-12-23 | |
| US62/096,464 | 2014-12-23 | ||
| PCT/EP2015/076353 WO2016075204A1 (en) | 2014-11-11 | 2015-11-11 | Methods and arrays for producing and sequencing monoclonal clusters of nucleic acid |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021213441A Division JP7323598B2 (ja) | 2014-11-11 | 2021-12-27 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017533710A JP2017533710A (ja) | 2017-11-16 |
| JP2017533710A5 true JP2017533710A5 (enExample) | 2018-12-20 |
| JP7032930B2 JP7032930B2 (ja) | 2022-03-09 |
Family
ID=54540094
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017524429A Active JP7032930B2 (ja) | 2014-11-11 | 2015-11-11 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
| JP2021213441A Active JP7323598B2 (ja) | 2014-11-11 | 2021-12-27 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021213441A Active JP7323598B2 (ja) | 2014-11-11 | 2021-12-27 | 核酸のモノクローナルクラスターの生成および配列決定のための方法およびアレイ |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US10619204B2 (enExample) |
| EP (1) | EP3218511B1 (enExample) |
| JP (2) | JP7032930B2 (enExample) |
| KR (1) | KR102590448B1 (enExample) |
| CN (1) | CN107208019B (enExample) |
| AU (1) | AU2015345125B2 (enExample) |
| CA (1) | CA2967525A1 (enExample) |
| DK (1) | DK3218511T3 (enExample) |
| ES (1) | ES2802405T3 (enExample) |
| MY (1) | MY182476A (enExample) |
| PL (1) | PL3218511T3 (enExample) |
| PT (1) | PT3218511T (enExample) |
| SG (2) | SG10202004350TA (enExample) |
| WO (1) | WO2016075204A1 (enExample) |
Families Citing this family (57)
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| EP3696277B2 (en) | 2013-07-30 | 2025-09-03 | President and Fellows of Harvard College | Quantitative dna-based imaging and super-resolution imaging |
| US10415083B2 (en) | 2013-10-28 | 2019-09-17 | The Translational Genomics Research Institute | Long insert-based whole genome sequencing |
| KR102590448B1 (ko) | 2014-11-11 | 2023-10-17 | 일루미나 케임브리지 리미티드 | 핵산의 모노클로날 클러스터를 형성시키고 시퀀싱하기 위한 방법 및 어레이 |
| CN107636169A (zh) * | 2015-04-17 | 2018-01-26 | 生捷科技控股公司 | 对生物分子进行空间概况分析的方法 |
| US11092606B2 (en) * | 2015-08-07 | 2021-08-17 | President And Fellows Of Harvard College | Super resolution imaging of protein-protein interactions |
| WO2017027653A1 (en) | 2015-08-11 | 2017-02-16 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| JP2017209051A (ja) * | 2016-05-25 | 2017-11-30 | 株式会社ニコン | 標的生体分子の検出方法、標的生体分子検出用基板、及び標的生体分子検出装置 |
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| NL2019044B1 (en) * | 2017-05-11 | 2018-11-15 | Illumina Inc | Protective surface coatings for flow cells |
| US11053537B2 (en) * | 2017-05-25 | 2021-07-06 | Integrated Dna Technologies, Inc. | Reverse complement adapters for the mitigation of UMI hopping |
| US11001885B2 (en) | 2017-06-13 | 2021-05-11 | Personal Genomics Taiwan, Inc. | Apparatus for single molecular sequencing and method of sequencing nucleic acid molecules |
| IL272470B2 (en) | 2017-08-07 | 2025-08-01 | Univ Johns Hopkins | Methods and materials for assessing and treating cancer |
| CN107523640A (zh) * | 2017-10-12 | 2017-12-29 | 厦门燕旭安生物科技有限公司 | 一种ctDNA精准测序的扩增子文库构建方法 |
| AU2018392919B2 (en) * | 2017-12-21 | 2021-04-15 | Illumina Cambridge Limited | Flow cells with hydrogel coating |
| JP2021525095A (ja) * | 2018-05-28 | 2021-09-24 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | Ｄｎａ−ポア−ポリメラーゼ複合体の酵素的濃縮 |
| AU2019275675A1 (en) | 2018-06-29 | 2020-01-16 | Illumina Cambridge Limited | Flow cells |
| TWI730352B (zh) | 2018-08-06 | 2021-06-11 | 英商伊路米納劍橋有限公司 | 流體槽與定序系統及製備用於其之基板的方法 |
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| EP3891305A1 (en) * | 2018-12-05 | 2021-10-13 | Illumina Cambridge Limited | Methods and compositions for cluster generation by bridge amplification |
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| CN112654715B (zh) * | 2018-12-19 | 2024-12-31 | 亿明达股份有限公司 | 改进多核苷酸簇克隆性优先性的方法 |
| TWI857001B (zh) | 2019-01-29 | 2024-10-01 | 美商伊路米納有限公司 | 定序套組 |
| TWI873119B (zh) * | 2019-01-29 | 2025-02-21 | 美商伊路米納有限公司 | 流通槽及製備其之方法 |
| TWI857000B (zh) | 2019-01-29 | 2024-10-01 | 美商伊路米納有限公司 | 流體槽以及將複合物引入至流體槽之方法 |
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| SG11202012826XA (en) * | 2019-05-31 | 2021-01-28 | Illumina Inc | Systems and methods for information storage and retrieval using flow cells |
| TW202120693A (zh) * | 2019-08-21 | 2021-06-01 | 美商伊路米納有限公司 | 偵測核苷酸之聚合酶併入的方法 |
| CA3135280A1 (en) * | 2019-12-16 | 2021-06-24 | Illumina, Inc. | Kits and flow cells |
| CA3145322A1 (en) | 2019-12-20 | 2021-06-24 | Illumina, Inc. | Flow cells |
| MX2021016074A (es) * | 2019-12-23 | 2022-03-29 | Illumina Inc | Nanoparticula con un solo sitio para la union de polinucleotido de plantilla. |
| CN115516108A (zh) | 2020-02-14 | 2022-12-23 | 约翰斯霍普金斯大学 | 评估核酸的方法和材料 |
| EP4107286A4 (en) * | 2020-02-19 | 2024-04-24 | Sequencing Health, Inc. | METHODS AND SYSTEMS FOR PROCESSING NUCLEIC ACIDS |
| MX2021015806A (es) * | 2020-02-26 | 2022-04-27 | Illumina Inc | Kits para genotipificacion. |
| AU2021230282A1 (en) * | 2020-03-03 | 2022-09-22 | Pacific Biosciences Of California, Inc. | Methods and compositions for sequencing double stranded nucleic acids |
| JP2023517156A (ja) * | 2020-03-09 | 2023-04-24 | イルミナ，インコーポレイテッド | 核酸配列決定における改善 |
| KR20230035237A (ko) | 2020-05-12 | 2023-03-13 | 일루미나, 인코포레이티드 | 재조합 말단 데옥시뉴클레오티딜 트랜스퍼라제를 사용하여 변형된 염기를 갖는 핵산의 생성 |
| MX2022014724A (es) * | 2020-09-14 | 2023-03-06 | Illumina Inc | Composiciones y metodos para amplificar polinucleótidos. |
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| US12298665B2 (en) | 2020-09-29 | 2025-05-13 | Illumina, Inc. | Flow cells and methods for making the same |
| US12264361B2 (en) * | 2020-12-10 | 2025-04-01 | Illumina, Inc. | Image sensor structures and related methods |
| US11884977B2 (en) | 2021-03-12 | 2024-01-30 | Singular Genomics Systems, Inc. | Nanoarrays and methods of use thereof |
| EP4263868A4 (en) * | 2021-03-12 | 2024-11-27 | Singular Genomics Systems, Inc. | NANONETWORKS AND METHODS OF USE THEREOF |
| BR112023022509A2 (pt) | 2021-04-30 | 2024-01-02 | Illumina Cambridge Ltd | Célula de fluxo e métodos |
| WO2022240764A1 (en) * | 2021-05-10 | 2022-11-17 | Pacific Biosciences Of California, Inc. | Single-molecule seeding and amplification on a surface |
| WO2024006625A1 (en) * | 2022-06-27 | 2024-01-04 | Somalogic Operating Co., Inc. | Monoclonal polony generation using nucleic acid supramolecular structures |
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| CN116024320A (zh) * | 2022-07-13 | 2023-04-28 | 上海翔琼生物技术有限公司 | 一种用于检测核酸的荧光定量pcr方法 |
| WO2024057089A1 (en) * | 2022-09-09 | 2024-03-21 | Todx Inc. | Device for parallel detection and quantification of nucleic acid based markers |
| CN119677869A (zh) * | 2022-09-16 | 2025-03-21 | 伊路米纳有限公司 | 具有多核苷酸结合位点的纳米颗粒及其制备方法 |
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-
2015
- 2015-11-11 KR KR1020177015817A patent/KR102590448B1/ko active Active
- 2015-11-11 PL PL15793823T patent/PL3218511T3/pl unknown
- 2015-11-11 JP JP2017524429A patent/JP7032930B2/ja active Active
- 2015-11-11 SG SG10202004350TA patent/SG10202004350TA/en unknown
- 2015-11-11 WO PCT/EP2015/076353 patent/WO2016075204A1/en not_active Ceased
- 2015-11-11 ES ES15793823T patent/ES2802405T3/es active Active
- 2015-11-11 PT PT157938234T patent/PT3218511T/pt unknown
- 2015-11-11 CN CN201580072860.9A patent/CN107208019B/zh active Active
- 2015-11-11 SG SG11201703693UA patent/SG11201703693UA/en unknown
- 2015-11-11 AU AU2015345125A patent/AU2015345125B2/en active Active
- 2015-11-11 MY MYPI2017000708A patent/MY182476A/en unknown
- 2015-11-11 CA CA2967525A patent/CA2967525A1/en active Pending
- 2015-11-11 US US15/525,892 patent/US10619204B2/en active Active
- 2015-11-11 DK DK15793823.4T patent/DK3218511T3/da active
- 2015-11-11 EP EP15793823.4A patent/EP3218511B1/en active Active
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2020
- 2020-04-10 US US16/846,028 patent/US11692223B2/en active Active
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2021
- 2021-12-27 JP JP2021213441A patent/JP7323598B2/ja active Active
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2023
- 2023-05-18 US US18/320,122 patent/US12385092B2/en active Active