JP2014030431A5 - - Google Patents

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Publication number
JP2014030431A5
JP2014030431A5 JP2013235628A JP2013235628A JP2014030431A5 JP 2014030431 A5 JP2014030431 A5 JP 2014030431A5 JP 2013235628 A JP2013235628 A JP 2013235628A JP 2013235628 A JP2013235628 A JP 2013235628A JP 2014030431 A5 JP2014030431 A5 JP 2014030431A5
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JP
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nucleic acid
target nucleic
concentration
amplicon species
hybridize
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JP2013235628A
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Japanese (ja)
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JP5863752B2 (ja
JP2014030431A (ja
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Publication of JP2014030431A5 publication Critical patent/JP2014030431A5/ja
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JP2013235628A 2009-07-21 2013-11-14 拡張されたダイナミックレンジにわたる核酸配列の定量的検出のための方法および組成物 Expired - Fee Related JP5863752B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22733909P 2009-07-21 2009-07-21
US61/227,339 2009-07-21
US23093809P 2009-08-03 2009-08-03
US61/230,938 2009-08-03

Related Parent Applications (1)

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JP2012521757A Division JP5575239B2 (ja) 2009-07-21 2010-07-21 拡張されたダイナミックレンジにわたる核酸配列の定量的検出のための方法および組成物

Related Child Applications (1)

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JP2015143645A Division JP2015186487A (ja) 2009-07-21 2015-07-21 拡張されたダイナミックレンジにわたる核酸配列の定量的検出のための方法および組成物

Publications (3)

Publication Number Publication Date
JP2014030431A JP2014030431A (ja) 2014-02-20
JP2014030431A5 true JP2014030431A5 (enExample) 2014-08-07
JP5863752B2 JP5863752B2 (ja) 2016-02-17

Family

ID=43084221

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2012521757A Expired - Fee Related JP5575239B2 (ja) 2009-07-21 2010-07-21 拡張されたダイナミックレンジにわたる核酸配列の定量的検出のための方法および組成物
JP2013235628A Expired - Fee Related JP5863752B2 (ja) 2009-07-21 2013-11-14 拡張されたダイナミックレンジにわたる核酸配列の定量的検出のための方法および組成物
JP2015143645A Withdrawn JP2015186487A (ja) 2009-07-21 2015-07-21 拡張されたダイナミックレンジにわたる核酸配列の定量的検出のための方法および組成物
JP2017114116A Pending JP2017148080A (ja) 2009-07-21 2017-06-09 拡張されたダイナミックレンジにわたる核酸配列の定量的検出のための方法および組成物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2012521757A Expired - Fee Related JP5575239B2 (ja) 2009-07-21 2010-07-21 拡張されたダイナミックレンジにわたる核酸配列の定量的検出のための方法および組成物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015143645A Withdrawn JP2015186487A (ja) 2009-07-21 2015-07-21 拡張されたダイナミックレンジにわたる核酸配列の定量的検出のための方法および組成物
JP2017114116A Pending JP2017148080A (ja) 2009-07-21 2017-06-09 拡張されたダイナミックレンジにわたる核酸配列の定量的検出のための方法および組成物

Country Status (6)

Country Link
US (5) US8628924B2 (enExample)
EP (3) EP3018218B1 (enExample)
JP (4) JP5575239B2 (enExample)
AU (1) AU2010276236B2 (enExample)
CA (1) CA2768391C (enExample)
WO (1) WO2011011535A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101550489B1 (ko) 2010-03-08 2015-09-07 다나-파버 캔서 인스티튜트 인크. 기준 차단 서열을 이용한 완전 cold-pcr 풍부화
EP3333269B1 (en) 2011-03-31 2021-05-05 Dana-Farber Cancer Institute, Inc. Methods to enable multiplex cold-pcr
US9133490B2 (en) * 2012-05-16 2015-09-15 Transgenomic, Inc. Step-up method for COLD-PCR enrichment
EP2749654A1 (en) * 2012-12-28 2014-07-02 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Method of analysis of composition of nucleic acid mixtures
JP6491458B2 (ja) * 2014-10-31 2019-03-27 シスメックス株式会社 核酸増幅方法
WO2018111835A1 (en) 2016-12-12 2018-06-21 Dana-Farber Cancer Institute, Inc. Compositions and methods for molecular barcoding of dna molecules prior to mutation enrichment and/or mutation detection
US10323289B2 (en) * 2017-06-26 2019-06-18 Institut Pasteur Treatments to eliminate HIV reservoirs and reduce viral load
US11174511B2 (en) 2017-07-24 2021-11-16 Dana-Farber Cancer Institute, Inc. Methods and compositions for selecting and amplifying DNA targets in a single reaction mixture
EP3628059B1 (en) * 2017-10-03 2023-04-12 Abbott Molecular Inc. Assay for detecting human immunodeficiency virus (hiv)

Family Cites Families (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486530A (en) 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4514505A (en) 1982-05-21 1985-04-30 The Trustees Of Columbia University In The City Of New York Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays
JPS60501339A (ja) 1983-01-10 1985-08-22 ジエン−プロ−ブ インコ−ポレィテッド 生物を検出、同定又は定量する方法およびキット
US4595661A (en) 1983-11-18 1986-06-17 Beckman Instruments, Inc. Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect
US4851334A (en) 1984-01-03 1989-07-25 The New York Blood Center, Inc. Monoclonal antibodies specific to in vivo fragments derived from human fibrinogen, human fibrin I or human fibrin II
US4766062A (en) 1984-05-07 1988-08-23 Allied Corporation Displacement polynucleotide assay method and polynucleotide complex reagent therefor
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US6040166A (en) 1985-03-28 2000-03-21 Roche Molecular Systems, Inc. Kits for amplifying and detecting nucleic acid sequences, including a probe
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US6197563B1 (en) 1985-03-28 2001-03-06 Roche Molecular Systems, Inc. Kits for amplifying and detecting nucleic acid sequences
US5004565A (en) 1986-07-17 1991-04-02 The Board Of Governors Of Wayne State University Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes
US5707559A (en) 1986-07-17 1998-01-13 Tropix, Inc. Chemiluminescent 1,2-dioxetane compounds
US5616729A (en) 1986-07-17 1997-04-01 Board Of Governors Of Wayne State University Enhanced chemiluminescence from 1,2-dioxetanes through energy transfer to tethered fluorescers
US5322770A (en) 1989-12-22 1994-06-21 Hoffman-Laroche Inc. Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription
US5310652A (en) 1986-08-22 1994-05-10 Hoffman-La Roche Inc. Reverse transcription with thermostable DNA polymerase-high temperature reverse transcription
US4745181A (en) 1986-10-06 1988-05-17 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
US5585481A (en) 1987-09-21 1996-12-17 Gen-Probe Incorporated Linking reagents for nucleotide probes
US5283174A (en) 1987-09-21 1994-02-01 Gen-Probe, Incorporated Homogenous protection assay
US5185439A (en) 1987-10-05 1993-02-09 Gen-Probe Incorporated Acridinium ester labelling and purification of nucleotide probes
US5130238A (en) 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
GB2233450B (en) 1989-06-24 1993-06-30 Univ Wales Medicine Detecting or quantifing multiple analytes with luminescent reagents
CA2020958C (en) 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
US5219727A (en) 1989-08-21 1993-06-15 Hoffmann-Laroche Inc. Quantitation of nucleic acids using the polymerase chain reaction
US5427930A (en) 1990-01-26 1995-06-27 Abbott Laboratories Amplification of target nucleic acids using gap filling ligase chain reaction
US5516663A (en) 1990-01-26 1996-05-14 Abbott Laboratories Ligase chain reaction with endonuclease IV correction and contamination control
US5312921A (en) 1990-03-14 1994-05-17 Regents Of The University Of California Dyes designed for high sensitivity detection of double-stranded DNA
US5200314A (en) 1990-03-23 1993-04-06 Chiron Corporation Polynucleotide capture assay employing in vitro amplification
AU687363B2 (en) 1993-03-19 1998-02-26 Ciba Corning Diagnostics Corp. Luminometer
US5395752A (en) 1993-03-19 1995-03-07 Ciba Corning Diagnostics Corp. Long emission wavelength chemiluminescent compounds and their use in test assays
US5876978A (en) 1993-04-06 1999-03-02 Medical College Of Ohio Method for quantitative measurement of gene expression using multiplex competitive reverse transcriptase-polymerase chain reaction
US5422252A (en) 1993-06-04 1995-06-06 Becton, Dickinson And Company Simultaneous amplification of multiple targets
JP3026843B2 (ja) 1993-07-23 2000-03-27 ジェン−プローブ・インコーポレーテッド 核酸増幅の促進法
US6156501A (en) 1993-10-26 2000-12-05 Affymetrix, Inc. Arrays of modified nucleic acid probes and methods of use
US5925517A (en) 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
GB9326238D0 (en) 1993-12-23 1994-02-23 Sinvent As Method of assay
US5648211A (en) 1994-04-18 1997-07-15 Becton, Dickinson And Company Strand displacement amplification using thermophilic enzymes
US5547861A (en) 1994-04-18 1996-08-20 Becton, Dickinson And Company Detection of nucleic acid amplification
US5514551A (en) 1994-10-14 1996-05-07 Gen-Probe Incorporated Compositions for the detection of Chlamydia trachomatis
EP0709466B1 (en) 1994-10-28 2006-09-27 Gen-Probe Incorporated Compositions and methods for the simultaneous detection and quantification of multiple specific nucleic acid sequences
JP3189000B2 (ja) 1994-12-01 2001-07-16 東ソー株式会社 特定核酸配列の検出方法
US5830645A (en) 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US6312894B1 (en) 1995-04-03 2001-11-06 Epoch Pharmaceuticals, Inc. Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders
US5648245A (en) 1995-05-09 1997-07-15 Carnegie Institution Of Washington Method for constructing an oligonucleotide concatamer library by rolling circle replication
US5514505A (en) * 1995-05-15 1996-05-07 Xerox Corporation Method for obtaining improved image contrast in migration imaging members
CA2221454A1 (en) 1995-05-19 1996-11-21 Abbott Laboratories Wide dynamic range nucleic acid detection using an aggregate primer series
US5705365A (en) 1995-06-07 1998-01-06 Gen-Probe Incorporated Kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
US5710029A (en) 1995-06-07 1998-01-20 Gen-Probe Incorporated Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
US5741650A (en) 1996-01-30 1998-04-21 Exact Laboratories, Inc. Methods for detecting colon cancer from stool samples
DE69739357D1 (de) 1996-06-04 2009-05-28 Univ Utah Res Found Überwachung der hybridisierung während pcr
US20020042048A1 (en) 1997-01-16 2002-04-11 Radoje Drmanac Methods and compositions for detection or quantification of nucleic acid species
JP3968810B2 (ja) 1997-01-24 2007-08-29 東ソー株式会社 核酸配列分析方法
US6143496A (en) 1997-04-17 2000-11-07 Cytonix Corporation Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
US6165800A (en) 1997-05-30 2000-12-26 Bayer Corporation Chemiluminescent energy transfer conjugates and their uses as labels in binding assays
US6368799B1 (en) 1997-06-13 2002-04-09 Affymetrix, Inc. Method to detect gene polymorphisms and monitor allelic expression employing a probe array
US6566101B1 (en) 1997-06-16 2003-05-20 Anthony P. Shuber Primer extension methods for detecting nucleic acids
AU1366299A (en) 1997-10-27 1999-05-17 Boston Probes, Inc. Methods, kits and compositions pertaining to pna molecular beacons
JP2001521754A (ja) 1997-10-30 2001-11-13 コールド スプリング ハーバー ラボラトリー Dna識別のためのプローブアレイ及びプローブアレイの使用方法
US6180340B1 (en) 1997-10-31 2001-01-30 Gen-Probe Incorporated Extended dynamic range assays
US5989823A (en) 1998-09-18 1999-11-23 Nexstar Pharmaceuticals, Inc. Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
AU3909199A (en) 1997-12-15 1999-07-05 Nexstar Pharmaceuticals, Inc. Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction
US6238869B1 (en) 1997-12-19 2001-05-29 High Throughput Genomics, Inc. High throughput assay system
US6268146B1 (en) 1998-03-13 2001-07-31 Promega Corporation Analytical methods and materials for nucleic acid detection
WO1999049293A2 (en) 1998-03-24 1999-09-30 Boston Probes, Inc. Methods, kits and compositions pertaining to detection complexes
AU3979099A (en) 1998-05-11 1999-11-29 Philadelphia Health & Education Corporation (mct-1), a human oncogene
US6066458A (en) 1998-05-18 2000-05-23 Becton, Dickinson And Company Methods, apparatus and computer program products for determining quantities of nucleic acid sequences in samples using standard curves and amplification ratio estimates
EP1092047B1 (en) 1998-07-02 2009-08-26 Gen-Probe Incorporated Molecular torches
US6037130A (en) 1998-07-28 2000-03-14 The Public Health Institute Of The City Of New York, Inc. Wavelength-shifting probes and primers and their use in assays and kits
US20020001800A1 (en) 1998-08-14 2002-01-03 Stanley N. Lapidus Diagnostic methods using serial testing of polymorphic loci
US6245517B1 (en) 1998-09-29 2001-06-12 The United States Of America As Represented By The Department Of Health And Human Services Ratio-based decisions and the quantitative analysis of cDNA micro-array images
US6238927B1 (en) 1998-10-05 2001-05-29 Mosaic Technologies, Incorporated Reverse displacement assay for detection of nucleic acid sequences
WO2000034521A1 (en) 1998-12-08 2000-06-15 Boston Probes, Inc. Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices
WO2000043552A2 (en) 1999-01-25 2000-07-27 Ut-Battelle, Llc Multifunctional and multispectral biosensor devices and methods of use
US6245511B1 (en) 1999-02-22 2001-06-12 Vialogy Corp Method and apparatus for exponentially convergent therapy effectiveness monitoring using DNA microarray based viral load measurements
WO2000060126A2 (en) 1999-04-08 2000-10-12 Sir Mortimer B. Davis Jewish General Hospital Quantitative assay for expression of genes in microarray
US6235479B1 (en) 1999-04-13 2001-05-22 Bio Merieux, Inc. Methods and devices for performing analysis of a nucleic acid sample
EP1046717B1 (en) 1999-04-20 2010-10-06 National Institute of Advanced Industrial Science and Technology Method and probes for determining a concentration of target nucleic acid molecules and method for analyzing data obtained by the method
ES2459745T3 (es) 1999-05-14 2014-05-12 Brandeis University Detección basada en aptámero
DE60014762T2 (de) 1999-05-24 2005-10-13 Tosoh Corp., Shinnanyo Methode zum Nachweis von Ribonukleinsäuren
AU5733900A (en) 1999-06-09 2000-12-28 Biosearch Technologies, Inc. Fluorescence energy transfer probes with stabilized conformations
WO2001007661A2 (en) 1999-07-23 2001-02-01 Gen-Probe Incorporated Polynucleotide amplification method
CA2387306C (en) 1999-10-22 2010-04-27 The Public Health Research Institute Of The City Of New York, Inc. Assays for short sequence variants
EP1096024A1 (en) 1999-10-28 2001-05-02 Remacle, José Method and kit for the screening and/or the quantification of multiple homologous nucleic acid sequences on arrays
GB2359625B (en) 1999-12-10 2004-10-20 Molecular Light Tech Res Ltd Monitoring oligonucleotide binding process using chemiluminescence quenching
US20040121364A1 (en) * 2000-02-07 2004-06-24 Mark Chee Multiplex nucleic acid reactions
DE10045521A1 (de) 2000-03-31 2001-10-04 Roche Diagnostics Gmbh Nukleinsäureamplifikationen
WO2001094625A2 (en) 2000-06-06 2001-12-13 Tm Bioscience Corporation Capture moieties for nucleic acids and uses thereof
CA2383939C (en) 2000-06-27 2009-12-01 National Institute Of Advanced Industrial Science And Technology Novel nucleic acid probes, method for determining nucleic acids by using the probes, and method for analyzing data obtained by the method
JP4291143B2 (ja) 2001-08-31 2009-07-08 ジェン−プロウブ インコーポレイテッド 分析物ポリヌクレオチドを定量するためのアフィニティーシフトしたプローブ
CA2468713A1 (en) 2001-11-30 2003-06-12 University Of Rochester Multiplex real-time quantitative pcr
US7198897B2 (en) 2001-12-19 2007-04-03 Brandeis University Late-PCR
CA2486420C (en) 2002-06-14 2014-04-15 Gen-Probe Incorporated Compositions and methods for detecting hepatitis b virus
AU2003272438B2 (en) 2002-09-20 2009-04-02 New England Biolabs, Inc. Helicase dependent amplification of nucleic acids
US7662594B2 (en) 2002-09-20 2010-02-16 New England Biolabs, Inc. Helicase-dependent amplification of RNA
WO2004102149A2 (en) * 2003-04-11 2004-11-25 Stratagene California Methods and compositions for the detection of bacterial species
GB0320236D0 (en) 2003-08-29 2003-10-01 Molecular Light Tech Res Ltd Chemiluminescent compounds
WO2006085964A2 (en) 2004-06-30 2006-08-17 Applera Corporation Log-linear amplification
WO2006004949A1 (en) 2004-06-30 2006-01-12 Applera Corporation Compositions and methods for detecting and quantitating polynucleotide sequences
CA2898814C (en) 2004-08-27 2015-12-29 Gen-Probe Incorporated Single-primer nucleic acid amplification methods
EP1799858A4 (en) * 2004-09-20 2009-03-04 Univ Pittsburgh MULTI MODE MULTIPLEX FIRE PROCEDURES
US20060088874A1 (en) * 2004-10-22 2006-04-27 Promega Corporation Methods and kits for detecting mutations
US20060246475A1 (en) 2005-01-21 2006-11-02 Third Wave Technologies Compositions and methods for increased dynamic range detection of nucleic acids
DE102006007778B3 (de) 2006-02-20 2007-11-08 Biotype Ag Verfahren zur Analyse von Multiplex-Gemischen bestehend aus Nukleinsäure-Amplifikationsprodukten mit überlappenden Detektionsbereichen
US20080131875A1 (en) 2006-06-07 2008-06-05 Third Wave Technologies, Inc. Multiplex assays
US20090181389A1 (en) * 2008-01-11 2009-07-16 Signosis, Inc., A California Corporation Quantitative measurement of nucleic acid via ligation-based linear amplification

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