JP2014520525A5 - - Google Patents

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JP2014520525A5
JP2014520525A5 JP2014518468A JP2014518468A JP2014520525A5 JP 2014520525 A5 JP2014520525 A5 JP 2014520525A5 JP 2014518468 A JP2014518468 A JP 2014518468A JP 2014518468 A JP2014518468 A JP 2014518468A JP 2014520525 A5 JP2014520525 A5 JP 2014520525A5
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probe
target
ligated
sequence
restricted
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JP2014518468A
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JP2014520525A (ja
JP6028025B2 (ja
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Priority claimed from PCT/NL2012/050493 external-priority patent/WO2013009175A1/en
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JP2014518468A 2011-07-08 2012-07-09 オリゴヌクレオチド・ライゲーション・アッセイに基づく配列ベースの遺伝子型決定 Active JP6028025B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161505787P 2011-07-08 2011-07-08
US61/505,787 2011-07-08
PCT/NL2012/050493 WO2013009175A1 (en) 2011-07-08 2012-07-09 Sequence based genotyping based on oligonucleotide ligation assays

Publications (3)

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JP2014520525A JP2014520525A (ja) 2014-08-25
JP2014520525A5 true JP2014520525A5 (enExample) 2015-08-27
JP6028025B2 JP6028025B2 (ja) 2016-11-16

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JP2014518468A Active JP6028025B2 (ja) 2011-07-08 2012-07-09 オリゴヌクレオチド・ライゲーション・アッセイに基づく配列ベースの遺伝子型決定

Country Status (8)

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US (4) US9777322B2 (enExample)
EP (2) EP2729580B1 (enExample)
JP (1) JP6028025B2 (enExample)
AU (1) AU2012281242B2 (enExample)
CA (1) CA2840929C (enExample)
DK (1) DK2729580T3 (enExample)
ES (1) ES2556580T3 (enExample)
WO (1) WO2013009175A1 (enExample)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11203786B2 (en) 2010-08-06 2021-12-21 Ariosa Diagnostics, Inc. Detection of target nucleic acids using hybridization
US20130040375A1 (en) 2011-08-08 2013-02-14 Tandem Diagnotics, Inc. Assay systems for genetic analysis
US20130261003A1 (en) 2010-08-06 2013-10-03 Ariosa Diagnostics, In. Ligation-based detection of genetic variants
US10533223B2 (en) 2010-08-06 2020-01-14 Ariosa Diagnostics, Inc. Detection of target nucleic acids using hybridization
US8700338B2 (en) 2011-01-25 2014-04-15 Ariosa Diagnosis, Inc. Risk calculation for evaluation of fetal aneuploidy
US20120034603A1 (en) 2010-08-06 2012-02-09 Tandem Diagnostics, Inc. Ligation-based detection of genetic variants
EP2729580B1 (en) * 2011-07-08 2015-09-16 Keygene N.V. Sequence based genotyping based on oligonucleotide ligation assays
DK2828218T3 (da) 2012-03-20 2020-11-02 Univ Washington Through Its Center For Commercialization Methods of lowering the error rate of massively parallel dna sequencing using duplex consensus sequencing
WO2013192292A1 (en) * 2012-06-21 2013-12-27 Justin Lamb Massively-parallel multiplex locus-specific nucleic acid sequence analysis
CN103958696B (zh) * 2012-09-10 2017-10-13 天昊生物医药科技(苏州)有限公司 多重核酸分析
US9270344B2 (en) * 2013-02-01 2016-02-23 Creating Revolutions, LLC Combination process interaction
CA2901138A1 (en) * 2013-03-12 2014-10-09 Counsyl, Inc. Systems and methods for prenatal genetic analysis
CN110283888B (zh) 2013-08-19 2021-06-22 卓异生物公司 用于单分子检测的测定及其应用
EP3149195B1 (en) 2014-06-02 2018-12-05 Base4 Innovation Ltd Nucleotide polymorphism detection method
JP6793112B2 (ja) * 2014-08-01 2020-12-02 アリオサ ダイアグノスティックス インコーポレイテッドAriosa Diagnostics,Inc. 胎児コピー数変異の統計的尤度を提供するアッセイ方法および胎児染色体異数性の尤度決定のためのアッセイ方法
CN104372093B (zh) 2014-11-10 2016-09-21 博奥生物集团有限公司 一种基于高通量测序的snp检测方法
CN107735497B (zh) * 2015-02-18 2021-08-20 卓异生物公司 用于单分子检测的测定及其应用
GB2536446B (en) * 2015-03-17 2020-06-03 Salisbury Nhs Found Trust PCR method
US10844428B2 (en) 2015-04-28 2020-11-24 Illumina, Inc. Error suppression in sequenced DNA fragments using redundant reads with unique molecular indices (UMIS)
WO2017027779A1 (en) * 2015-08-13 2017-02-16 Centrillion Technology Holdings Corporation Library construction using y-adapters and vanishing restriction sites
PT3387152T (pt) 2015-12-08 2022-04-19 Twinstrand Biosciences Inc Adaptadores, métodos e composições melhorados para sequenciamento duplex
EP3565906B1 (en) * 2017-01-05 2021-01-27 Tervisetehnoloogiate Arenduskeskus AS Quantifying dna sequences
CA3050247A1 (en) 2017-01-18 2018-07-26 Illumina, Inc. Methods and systems for generation and error-correction of unique molecular index sets with heterogeneous molecular lengths
US11447818B2 (en) 2017-09-15 2022-09-20 Illumina, Inc. Universal short adapters with variable length non-random unique molecular identifiers
EP3707273B1 (en) 2017-11-08 2024-04-10 Twinstrand Biosciences, Inc. Reagents and adapters for nucleic acid sequencing and methods for making such reagents and adapters
US11639928B2 (en) 2018-02-22 2023-05-02 10X Genomics, Inc. Methods and systems for characterizing analytes from individual cells or cell populations
CN112041462B (zh) * 2018-03-23 2024-06-07 德克萨斯州立大学董事会 具有极低的错误水平的dsDNA有效测序
CA3102892A1 (en) 2018-06-12 2019-12-19 Keygene N.V. Nucleic acid amplification method
KR20210059694A (ko) 2018-07-12 2021-05-25 트윈스트랜드 바이오사이언시스, 인코포레이티드 게놈 편집, 클론 팽창 및 연관된 분야를 규명하기 위한 방법 및 시약
EP3906320A4 (en) * 2019-01-04 2022-10-19 William Marsh Rice University QUANTITATIVE AMPLICON SEQUENCE FOR DETECTING MULTIPLEXIZED COPY NUMBER VARIATIONS AND ALLEL RATIO QUANTIZATION
CN113474466A (zh) 2019-02-21 2021-10-01 主基因有限公司 多倍体基因分型
EP4028545A4 (en) * 2019-09-09 2023-10-25 Sherlock Biosciences, Inc. SYSTEM
EP4028585A1 (en) * 2019-09-12 2022-07-20 GlaxoSmithKline Intellectual Property Development Limited Method for screening libraries
EP4298244A1 (en) 2021-02-23 2024-01-03 10X Genomics, Inc. Probe-based analysis of nucleic acids and proteins
WO2023081373A1 (en) * 2021-11-04 2023-05-11 Florida State University Research Foundation, Inc. Using hairpin formation to identify dna and rna sequences having a target nucleic acid sequence
CN117987521A (zh) * 2023-02-08 2024-05-07 深圳市真迈生物科技有限公司 测序方法
CN118006735B (zh) * 2023-05-30 2025-07-04 深圳赛陆医疗科技有限公司 一种snp芯片及其制备方法和应用

Family Cites Families (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242794A (en) 1984-12-13 1993-09-07 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
US4883750A (en) 1984-12-13 1989-11-28 Applied Biosystems, Inc. Detection of specific sequences in nucleic acids
GB8612087D0 (en) 1986-05-19 1986-06-25 Ici Plc Hybridisation probes
CA1323293C (en) 1987-12-11 1993-10-19 Keith C. Backman Assay using template-dependent nucleic acid probe reorganization
US4988617A (en) 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
DE68926504T2 (de) 1988-07-20 1996-09-12 David Segev Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen
US5185243A (en) 1988-08-25 1993-02-09 Syntex (U.S.A.) Inc. Method for detection of specific nucleic acid sequences
ATE137269T1 (de) 1990-01-26 1996-05-15 Abbott Lab Verbessertes verfahren zur amplifikation von nuklein säurezielsequenz, einsetzbar für die polymerase und ligasekettenreaktion
CA2119557C (en) 1991-09-24 2004-02-24 Marc Zabeau Selective restriction fragment amplification: a general method for dna fingerprinting
US5470705A (en) 1992-04-03 1995-11-28 Applied Biosystems, Inc. Probe composition containing a binding domain and polymer chain and methods of use
DE69433010T2 (de) 1993-04-12 2004-06-09 Northwestern University, Evanston Verfahren zur darstellung von oligonukleotiden
US5692223A (en) 1993-10-22 1997-11-25 Minolta Co., Ltd. Remotely-controlled flash photographing system
SE9400522D0 (sv) 1994-02-16 1994-02-16 Ulf Landegren Method and reagent for detecting specific nucleotide sequences
US5876924A (en) 1994-06-22 1999-03-02 Mount Sinai School Of Medicine Nucleic acid amplification method hybridization signal amplification method (HSAM)
US20070269799A9 (en) 1994-06-22 2007-11-22 Zhang David Y Nucleic acid amplification methods
US5942391A (en) 1994-06-22 1999-08-24 Mount Sinai School Of Medicine Nucleic acid amplification method: ramification-extension amplification method (RAM)
WO1996015271A1 (en) 1994-11-16 1996-05-23 Abbott Laboratories Multiplex ligations-dependent amplification
SE506908C2 (sv) 1995-09-08 1998-03-02 Ulf Landegren Inst F Medicinsk Medicinsk användning av padlockprober
JP4468488B2 (ja) 1996-05-29 2010-05-26 コーネル・リサーチ・ファンデーション・インコーポレイテッド 組み合せたリガーゼ検出およびポリメラーゼ連鎖反応を用いる核酸配列相違の検出
US6312892B1 (en) 1996-07-19 2001-11-06 Cornell Research Foundation, Inc. High fidelity detection of nucleic acid differences by ligase detection reaction
EP0974672B1 (en) 1998-07-21 2003-04-09 Keygene N.V. Improved primers for AFLP amplification
IL141148A0 (en) 1998-07-30 2002-02-10 Solexa Ltd Arrayed biomolecules and their use in sequencing
GB0002310D0 (en) 2000-02-01 2000-03-22 Solexa Ltd Polynucleotide sequencing
EP1131153A1 (en) 1998-11-06 2001-09-12 Solexa Ltd. A method for reproducing molecular arrays
WO2000058507A1 (en) 1999-03-30 2000-10-05 Solexa Ltd. Polynucleotide sequencing
US20020086289A1 (en) 1999-06-15 2002-07-04 Don Straus Genomic profiling: a rapid method for testing a complex biological sample for the presence of many types of organisms
US6156178A (en) 1999-07-13 2000-12-05 Molecular Dynamics, Inc. Increased throughput analysis of small compounds using multiple temporally spaced injections
EP1218543A2 (en) 1999-09-29 2002-07-03 Solexa Ltd. Polynucleotide sequencing
GB0002389D0 (en) 2000-02-02 2000-03-22 Solexa Ltd Molecular arrays
US6221603B1 (en) 2000-02-04 2001-04-24 Molecular Dynamics, Inc. Rolling circle amplification assay for nucleic acid analysis
EP1130113A1 (en) 2000-02-15 2001-09-05 Johannes Petrus Schouten Multiplex ligation dependent amplification assay
WO2001092579A2 (en) 2000-05-30 2001-12-06 Pe Corporation (Ny) Methods for detecting target nucleic acids using coupled ligation and amplification
EP1356119B1 (en) 2001-01-30 2007-09-26 Solexa Ltd. The preparation of polynucleotide arrays
US20050009022A1 (en) 2001-07-06 2005-01-13 Weiner Michael P. Method for isolation of independent, parallel chemical micro-reactions using a porous filter
GB0119719D0 (en) 2001-08-13 2001-10-03 Solexa Ltd DNA sequence analysis
US6902921B2 (en) 2001-10-30 2005-06-07 454 Corporation Sulfurylase-luciferase fusion proteins and thermostable sulfurylase
US7057026B2 (en) 2001-12-04 2006-06-06 Solexa Limited Labelled nucleotides
US20030119004A1 (en) 2001-12-05 2003-06-26 Wenz H. Michael Methods for quantitating nucleic acids using coupled ligation and amplification
EP1319718A1 (en) 2001-12-14 2003-06-18 Keygene N.V. High throughput analysis and detection of multiple target sequences
DE10162904B4 (de) 2001-12-20 2006-05-11 Jeyes Deutschland Gmbh Vorrichtung zur Abgabe eines flüssigen Wirkstoffs in ein Spülwasser
US20060088826A1 (en) 2001-12-28 2006-04-27 Van Eijk Michael Josephus Ther Discrimination and detection of target nucleotide sequences using mass spectrometry
ES2864086T3 (es) 2002-08-23 2021-10-13 Illumina Cambridge Ltd Nucleótidos etiquetados
AU2003259350A1 (en) 2002-08-23 2004-03-11 Solexa Limited Modified nucleotides for polynucleotide sequencing
DE60331852D1 (de) 2002-12-02 2010-05-06 Illumina Cambridge Ltd Bestimmung der methylierung von nukleinsäuresequenzen
AU2004209001B2 (en) 2003-01-29 2007-10-11 454 Life Sciences Corporation Bead emulsion nucleic acid amplification
GB0304371D0 (en) 2003-02-26 2003-04-02 Solexa Ltd DNA Sequence analysis
WO2005001129A2 (en) * 2003-06-06 2005-01-06 Applera Corporation Mobility cassettes
PL1633888T3 (pl) 2003-06-17 2009-10-30 Keygene Nv Środki i sposoby detekcji docelowych sekwencji nukleotydowych z użyciem oznaczeń ligacji i par ulepszonych sond oligonukleotydowych
GB0320059D0 (en) 2003-08-27 2003-10-01 Solexa Ltd A method of sequencing
WO2005026389A2 (en) * 2003-08-29 2005-03-24 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Ligation-based method of analysis of single nucleotide polymorphisms on genomic dna
ES2539784T3 (es) 2003-09-02 2015-07-06 Keygene N.V. Procedimientos basados en OLA para la detección de secuencias de ácidos nucleicos objetivo
EP1602733A1 (en) 2004-06-02 2005-12-07 Keygene N.V. Detection of target nucleotide sequences using an asymmetric oligonucleotide ligation assay
GB0326073D0 (en) 2003-11-07 2003-12-10 Solexa Ltd Improvements in or relating to polynucleotide arrays
WO2005065814A1 (en) 2004-01-07 2005-07-21 Solexa Limited Modified molecular arrays
GB0400584D0 (en) 2004-01-12 2004-02-11 Solexa Ltd Nucleic acid chacterisation
GB0400974D0 (en) 2004-01-16 2004-02-18 Solexa Ltd Multiple inexact matching
GB0402895D0 (en) 2004-02-10 2004-03-17 Solexa Ltd Arrayed polynucleotides
US20060211000A1 (en) * 2005-03-21 2006-09-21 Sorge Joseph A Methods, compositions, and kits for detection of microRNA
US7601499B2 (en) 2005-06-06 2009-10-13 454 Life Sciences Corporation Paired end sequencing
ES2558124T3 (es) * 2005-12-22 2016-02-02 Keygene N.V. Procedimiento para detección de polimorfismos basada en AFLP de alto rendimiento
WO2007101075A2 (en) * 2006-02-22 2007-09-07 Applera Corporation Double-ligation method for haplotype and large-scale polymorphism detection
WO2007100243A1 (en) 2006-03-01 2007-09-07 Keygene N.V. High throughput sequence-based detection of snps using ligation assays
EP2639578B1 (en) 2006-12-14 2016-09-14 Life Technologies Corporation Apparatus for measuring analytes using large scale fet arrays
US8349167B2 (en) 2006-12-14 2013-01-08 Life Technologies Corporation Methods and apparatus for detecting molecular interactions using FET arrays
WO2009092035A2 (en) 2008-01-17 2009-07-23 Sequenom, Inc. Methods and compositions for the analysis of biological molecules
EP2982437B1 (en) 2008-06-25 2017-12-06 Life Technologies Corporation Methods and apparatus for measuring analytes using large scale fet arrays
EP3650847A1 (en) 2008-06-26 2020-05-13 Life Technologies Corporation Methods and apparatus for detecting molecular interactions using fet arrays
US20100035252A1 (en) 2008-08-08 2010-02-11 Ion Torrent Systems Incorporated Methods for sequencing individual nucleic acids under tension
US8546128B2 (en) 2008-10-22 2013-10-01 Life Technologies Corporation Fluidics system for sequential delivery of reagents
CN103884760A (zh) 2008-10-22 2014-06-25 生命技术公司 单芯片化学测定装置和单芯片核酸测定装置
US20100301398A1 (en) 2009-05-29 2010-12-02 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes
US20100137143A1 (en) 2008-10-22 2010-06-03 Ion Torrent Systems Incorporated Methods and apparatus for measuring analytes
AU2010242073C1 (en) 2009-04-30 2015-12-24 Good Start Genetics, Inc. Methods and compositions for evaluating genetic markers
EP2435461B1 (en) 2009-05-29 2017-08-09 Life Technologies Corporation Scaffolded nucleic acid polymer particles and methods of making and using
US8673627B2 (en) 2009-05-29 2014-03-18 Life Technologies Corporation Apparatus and methods for performing electrochemical reactions
US8574835B2 (en) 2009-05-29 2013-11-05 Life Technologies Corporation Scaffolded nucleic acid polymer particles and methods of making and using
US20120034603A1 (en) 2010-08-06 2012-02-09 Tandem Diagnostics, Inc. Ligation-based detection of genetic variants
EP2603607B1 (en) 2010-08-11 2016-04-06 Celula, Inc. Genotyping dna
EP2710145B1 (en) 2011-05-17 2015-12-09 Dxterity Diagnostics Incorporated Methods and compositions for detecting target nucleic acids
EP2729580B1 (en) * 2011-07-08 2015-09-16 Keygene N.V. Sequence based genotyping based on oligonucleotide ligation assays

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