CA2840929C - Sequence based genotyping based on oligonucleotide ligation assays - Google Patents
Sequence based genotyping based on oligonucleotide ligation assays Download PDFInfo
- Publication number
- CA2840929C CA2840929C CA2840929A CA2840929A CA2840929C CA 2840929 C CA2840929 C CA 2840929C CA 2840929 A CA2840929 A CA 2840929A CA 2840929 A CA2840929 A CA 2840929A CA 2840929 C CA2840929 C CA 2840929C
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- CA
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- Prior art keywords
- sequence
- probes
- probe
- target
- sequencing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
- C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Chemical Kinetics & Catalysis (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161505787P | 2011-07-08 | 2011-07-08 | |
| US61/505,787 | 2011-07-08 | ||
| PCT/NL2012/050493 WO2013009175A1 (en) | 2011-07-08 | 2012-07-09 | Sequence based genotyping based on oligonucleotide ligation assays |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2840929A1 CA2840929A1 (en) | 2013-01-17 |
| CA2840929C true CA2840929C (en) | 2020-03-24 |
Family
ID=46579302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2840929A Active CA2840929C (en) | 2011-07-08 | 2012-07-09 | Sequence based genotyping based on oligonucleotide ligation assays |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US9777322B2 (enExample) |
| EP (2) | EP2729580B1 (enExample) |
| JP (1) | JP6028025B2 (enExample) |
| AU (1) | AU2012281242B2 (enExample) |
| CA (1) | CA2840929C (enExample) |
| DK (1) | DK2729580T3 (enExample) |
| ES (1) | ES2556580T3 (enExample) |
| WO (1) | WO2013009175A1 (enExample) |
Families Citing this family (37)
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| US20120034603A1 (en) | 2010-08-06 | 2012-02-09 | Tandem Diagnostics, Inc. | Ligation-based detection of genetic variants |
| US11203786B2 (en) | 2010-08-06 | 2021-12-21 | Ariosa Diagnostics, Inc. | Detection of target nucleic acids using hybridization |
| US20130040375A1 (en) | 2011-08-08 | 2013-02-14 | Tandem Diagnotics, Inc. | Assay systems for genetic analysis |
| US20130261003A1 (en) | 2010-08-06 | 2013-10-03 | Ariosa Diagnostics, In. | Ligation-based detection of genetic variants |
| US10533223B2 (en) | 2010-08-06 | 2020-01-14 | Ariosa Diagnostics, Inc. | Detection of target nucleic acids using hybridization |
| US8700338B2 (en) | 2011-01-25 | 2014-04-15 | Ariosa Diagnosis, Inc. | Risk calculation for evaluation of fetal aneuploidy |
| DK2729580T3 (en) * | 2011-07-08 | 2015-12-14 | Keygene Nv | SEQUENCE BASED genotyping BASED ON OLIGONUKLEOTIDLIGERINGSASSAYS |
| PT2828218T (pt) | 2012-03-20 | 2020-11-11 | Univ Washington Through Its Center For Commercialization | Métodos para baixar a taxa de erro da sequenciação paralela massiva de adn utilizando sequenciação duplex de consensus |
| WO2013192292A1 (en) * | 2012-06-21 | 2013-12-27 | Justin Lamb | Massively-parallel multiplex locus-specific nucleic acid sequence analysis |
| JP6234463B2 (ja) * | 2012-09-10 | 2017-11-22 | ジーンスカイ ダイアグノスティクス（スーツォウ） インコーポレーテッドＧｅｎｅｓｋｙ Ｄｉａｇｎｏｓｔｉｃｓ （Ｓｕｚｈｏｕ） Ｉｎｃ． | 核酸の多重分析の方法 |
| US9270344B2 (en) * | 2013-02-01 | 2016-02-23 | Creating Revolutions, LLC | Combination process interaction |
| WO2014165267A2 (en) * | 2013-03-12 | 2014-10-09 | Counsyl, Inc. | Systems and methods for prenatal genetic analysis |
| IL285521B2 (en) | 2013-08-19 | 2023-03-01 | Singular Bio Inc | Methods for single molecule detection |
| WO2015185564A1 (en) * | 2014-06-02 | 2015-12-10 | Base4 Innovation Ltd | Nucleotide polymorphism detection method |
| JP6793112B2 (ja) * | 2014-08-01 | 2020-12-02 | アリオサ ダイアグノスティックス インコーポレイテッドＡｒｉｏｓａ Ｄｉａｇｎｏｓｔｉｃｓ，Ｉｎｃ． | 胎児コピー数変異の統計的尤度を提供するアッセイ方法および胎児染色体異数性の尤度決定のためのアッセイ方法 |
| CN104372093B (zh) * | 2014-11-10 | 2016-09-21 | 博奥生物集团有限公司 | 一种基于高通量测序的snp检测方法 |
| CN113528623A (zh) * | 2015-02-18 | 2021-10-22 | 卓异生物公司 | 用于单分子检测的测定及其应用 |
| GB2536446B (en) * | 2015-03-17 | 2020-06-03 | Salisbury Nhs Found Trust | PCR method |
| US10844428B2 (en) * | 2015-04-28 | 2020-11-24 | Illumina, Inc. | Error suppression in sequenced DNA fragments using redundant reads with unique molecular indices (UMIS) |
| US10689690B2 (en) | 2015-08-13 | 2020-06-23 | Centrillion Technology Holdings Corporation | Library construction using Y-adapters and vanishing restriction sites |
| CA3006792A1 (en) | 2015-12-08 | 2017-06-15 | Twinstrand Biosciences, Inc. | Improved adapters, methods, and compositions for duplex sequencing |
| EP3565906B1 (en) * | 2017-01-05 | 2021-01-27 | Tervisetehnoloogiate Arenduskeskus AS | Quantifying dna sequences |
| SG11201906428SA (en) | 2017-01-18 | 2019-08-27 | Illumina Inc | Methods and systems for generation and error-correction of unique molecular index sets with heterogeneous molecular lengths |
| US11447818B2 (en) | 2017-09-15 | 2022-09-20 | Illumina, Inc. | Universal short adapters with variable length non-random unique molecular identifiers |
| AU2018366213B2 (en) | 2017-11-08 | 2025-05-15 | Twinstrand Biosciences, Inc. | Reagents and adapters for nucleic acid sequencing and methods for making such reagents and adapters |
| US11639928B2 (en) * | 2018-02-22 | 2023-05-02 | 10X Genomics, Inc. | Methods and systems for characterizing analytes from individual cells or cell populations |
| EP3768853A4 (en) * | 2018-03-23 | 2021-04-28 | Board Of Regents The University Of Texas System | EFFICIENT SEQUENCING OF DSDNA WITH EXTREMELY LOW ERROR RATE |
| AU2019287163B2 (en) | 2018-06-12 | 2025-08-21 | Keygene N.V. | Nucleic acid amplification method |
| BR112021000409A2 (pt) | 2018-07-12 | 2021-04-06 | Twinstrand Biosciences, Inc. | Métodos e reagentes para caracterizar edição genômica, expansão clonal e aplicações associadas |
| CA3125458A1 (en) * | 2019-01-04 | 2020-07-09 | William Marsh Rice University | Quantitative amplicon sequencing for multiplexed copy number variation detection and allele ratio quantitation |
| CA3127572A1 (en) | 2019-02-21 | 2020-08-27 | Keygene N.V. | Genotyping of polyploids |
| WO2021050560A1 (en) * | 2019-09-09 | 2021-03-18 | Sherlock Biosciences | System |
| JP2022547699A (ja) * | 2019-09-12 | 2022-11-15 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド | ライブラリーのスクリーニング方法 |
| CN117015617B (zh) | 2021-02-23 | 2025-04-04 | 10X基因组学有限公司 | 基于探针的核酸和蛋白质分析 |
| US12601008B2 (en) | 2021-11-04 | 2026-04-14 | Florida State University Research Foundation, Inc. | Using hairpin formation to identify DNA and RNA sequences having a target nucleic acid sequence |
| CN117987521A (zh) * | 2023-02-08 | 2024-05-07 | 深圳市真迈生物科技有限公司 | 测序方法 |
| CN118006735B (zh) * | 2023-05-30 | 2025-07-04 | 深圳赛陆医疗科技有限公司 | 一种snp芯片及其制备方法和应用 |
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| DK2729580T3 (en) * | 2011-07-08 | 2015-12-14 | Keygene Nv | SEQUENCE BASED genotyping BASED ON OLIGONUKLEOTIDLIGERINGSASSAYS |
-
2012
- 2012-07-09 DK DK12738652.2T patent/DK2729580T3/en active
- 2012-07-09 CA CA2840929A patent/CA2840929C/en active Active
- 2012-07-09 AU AU2012281242A patent/AU2012281242B2/en not_active Ceased
- 2012-07-09 US US14/131,181 patent/US9777322B2/en active Active
- 2012-07-09 EP EP12738652.2A patent/EP2729580B1/en active Active
- 2012-07-09 EP EP15185310.8A patent/EP2980226A1/en not_active Withdrawn
- 2012-07-09 JP JP2014518468A patent/JP6028025B2/ja active Active
- 2012-07-09 WO PCT/NL2012/050493 patent/WO2013009175A1/en not_active Ceased
- 2012-07-09 ES ES12738652.2T patent/ES2556580T3/es active Active
-
2017
- 2017-08-22 US US15/683,063 patent/US10422001B2/en active Active
-
2019
- 2019-08-13 US US16/539,119 patent/US10988807B2/en active Active
-
2021
- 2021-03-22 US US17/208,728 patent/US11873529B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20200071757A1 (en) | 2020-03-05 |
| US11873529B2 (en) | 2024-01-16 |
| EP2729580A1 (en) | 2014-05-14 |
| AU2012281242B2 (en) | 2016-12-22 |
| JP2014520525A (ja) | 2014-08-25 |
| US20180023135A1 (en) | 2018-01-25 |
| WO2013009175A1 (en) | 2013-01-17 |
| US20140221217A1 (en) | 2014-08-07 |
| US9777322B2 (en) | 2017-10-03 |
| EP2980226A1 (en) | 2016-02-03 |
| JP6028025B2 (ja) | 2016-11-16 |
| US20210207213A1 (en) | 2021-07-08 |
| CA2840929A1 (en) | 2013-01-17 |
| DK2729580T3 (en) | 2015-12-14 |
| AU2012281242A1 (en) | 2014-02-27 |
| US10422001B2 (en) | 2019-09-24 |
| ES2556580T3 (es) | 2016-01-19 |
| EP2729580B1 (en) | 2015-09-16 |
| US10988807B2 (en) | 2021-04-27 |
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