ATE516371T1 - Oligonukleotide und deren verwendungen - Google Patents

Oligonukleotide und deren verwendungen

Info

Publication number
ATE516371T1
ATE516371T1 AT08842916T AT08842916T ATE516371T1 AT E516371 T1 ATE516371 T1 AT E516371T1 AT 08842916 T AT08842916 T AT 08842916T AT 08842916 T AT08842916 T AT 08842916T AT E516371 T1 ATE516371 T1 AT E516371T1
Authority
AT
Austria
Prior art keywords
target polynucleotide
tandem repeats
single stranded
probe oligonucleotide
stranded portion
Prior art date
Application number
AT08842916T
Other languages
English (en)
Inventor
Nittaya Gale
Paul Debenham
David French
Rebecca Howard
David Mcdowell
Tom Brown
Original Assignee
Lgc Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0720675A external-priority patent/GB0720675D0/en
Priority claimed from GB0815113A external-priority patent/GB0815113D0/en
Application filed by Lgc Ltd filed Critical Lgc Ltd
Application granted granted Critical
Publication of ATE516371T1 publication Critical patent/ATE516371T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT08842916T 2007-10-22 2008-10-21 Oligonukleotide und deren verwendungen ATE516371T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0720675A GB0720675D0 (en) 2007-10-22 2007-10-22 Oligonucleotides and uses thereof
GB0815113A GB0815113D0 (en) 2008-08-19 2008-08-19 Oligonucleotides and uses thereof
PCT/GB2008/003555 WO2009053679A1 (en) 2007-10-22 2008-10-21 Oligonucleotides and uses thereof

Publications (1)

Publication Number Publication Date
ATE516371T1 true ATE516371T1 (de) 2011-07-15

Family

ID=40202890

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08842916T ATE516371T1 (de) 2007-10-22 2008-10-21 Oligonukleotide und deren verwendungen

Country Status (12)

Country Link
US (1) US9404148B2 (de)
EP (1) EP2217719B1 (de)
JP (1) JP5604302B2 (de)
CN (1) CN101896623B (de)
AT (1) ATE516371T1 (de)
AU (1) AU2008315791B2 (de)
CA (1) CA2703227C (de)
ES (1) ES2395240T3 (de)
HK (1) HK1147524A1 (de)
NZ (1) NZ584739A (de)
PT (1) PT2217719E (de)
WO (1) WO2009053679A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170119729A (ko) 2009-02-13 2017-10-27 엑스-켐, 인크. Ｄｎａ―코딩된 라이브러리의 생성 및 스크리닝 방법
JP5716217B2 (ja) * 2009-12-15 2015-05-13 公益財団法人ヒューマンサイエンス振興財団 長鎖繰返し配列を含有する遺伝子又は遺伝子産物の選択又は優先的回収方法
GB201010237D0 (en) 2010-06-18 2010-07-21 Lgc Ltd Methods and apparatuses
CA2820715C (en) * 2010-12-16 2020-03-31 Bio-Rad Laboratories, Inc. Universal reference dye for quantitative amplification
EP2663651B1 (de) * 2011-01-14 2018-06-20 Genefirst Limited Verfahren, zusammensetzungen und kits zur bestimmung der an-/abwesenheit einer varianten nukleinsäuresequenz
US10865409B2 (en) 2011-09-07 2020-12-15 X-Chem, Inc. Methods for tagging DNA-encoded libraries
GB201116131D0 (en) * 2011-09-19 2011-11-02 Epistem Ltd Probe
WO2013106807A1 (en) * 2012-01-13 2013-07-18 Curry John D Scalable characterization of nucleic acids by parallel sequencing
US20130183666A1 (en) 2012-01-18 2013-07-18 Marc N. Feiglin Partial genotyping by differential hybridization
AU2013289993B2 (en) 2012-07-13 2018-05-10 X-Chem, Inc. DNA-encoded libraries having encoding oligonucleotide linkages not readable by polymerases
US9437397B2 (en) * 2013-06-27 2016-09-06 Varian Semiconductor Equipment Associates, Inc. Textured silicon liners in substrate processing systems
WO2015120406A1 (en) 2014-02-07 2015-08-13 University Of Iowa Research Foundation Oligonucleotide-based probes and methods for detection of microbes
US11118216B2 (en) 2015-09-08 2021-09-14 Affymetrix, Inc. Nucleic acid analysis by joining barcoded polynucleotide probes
JP6685138B2 (ja) * 2016-01-27 2020-04-22 シスメックス株式会社 核酸増幅の精度管理方法、精度管理用試薬およびその試薬キット
US10718017B2 (en) * 2016-03-31 2020-07-21 Arizona Board Of Regents On Behalf Of Arizona State University Probes and methods for measuring tandem repeats
WO2021030271A2 (en) 2019-08-09 2021-02-18 Nutcracker Therapeutics, Inc. Methods and apparatuses for manufacturing for removing material from a therapeutic composition
CN114599975A (zh) * 2019-10-22 2022-06-07 生物辐射实验室股份有限公司 使用增强荧光检测的基材在单分子水平上检测分子相互作用
CN110951878B (zh) * 2019-12-20 2023-02-28 北京优迅医学检验实验室有限公司 与基因组稳定性相关的微卫星位点的筛选方法、筛选装置及应用
AU2021231104A1 (en) 2020-03-03 2022-07-21 Universiteit Gent Hydrolysis-based probe and method for STR genotyping

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5210015A (en) * 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US6207373B1 (en) * 1998-02-25 2001-03-27 Nanogen, Inc. Methods for determining nature of repeat units in DNA
US6465183B2 (en) * 1999-07-01 2002-10-15 Agilent Technologies, Inc. Multidentate arrays
DE60143974D1 (de) * 2000-03-29 2011-03-10 Lgc Ltd Hybridisierungsprobe und Methode zum schnellen Nachweis und zur schnellen Unterscheidung von Sequenzen
DE60113945T2 (de) * 2000-11-15 2006-06-29 Roche Diagnostics Gmbh Verfahren zur Analyse von Wiederkehrenden PCR-Podukten, das auf der Analyse von DNS-Schmelzkurven basiert
US20060008823A1 (en) 2004-05-12 2006-01-12 Kemp Jennifer T DNA profiling and SNP detection utilizing microarrays
GB0514889D0 (en) 2005-07-20 2005-08-24 Lgc Ltd Oligonucleotides
US7977108B2 (en) 2005-07-25 2011-07-12 Roche Molecular Systems, Inc. Method for detecting a mutation in a repetitive nucleic acid sequence
CN101421406B (zh) * 2006-02-13 2016-08-31 孟山都技术有限公司 用于产生改变的种子油组成的核酸构建体和方法

Also Published As

Publication number Publication date
JP5604302B2 (ja) 2014-10-08
WO2009053679A1 (en) 2009-04-30
CN101896623A (zh) 2010-11-24
NZ584739A (en) 2012-06-29
ES2395240T3 (es) 2013-02-11
US20110003290A1 (en) 2011-01-06
EP2217719B1 (de) 2011-07-13
JP2011507488A (ja) 2011-03-10
CA2703227C (en) 2017-02-28
PT2217719E (pt) 2011-10-03
CN101896623B (zh) 2013-12-18
HK1147524A1 (en) 2011-08-12
CA2703227A1 (en) 2009-04-30
AU2008315791A1 (en) 2009-04-30
US9404148B2 (en) 2016-08-02
AU2008315791B2 (en) 2014-04-10
EP2217719A1 (de) 2010-08-18

Similar Documents

Publication Publication Date Title
ATE516371T1 (de) Oligonukleotide und deren verwendungen
FI3872187T3 (fi) Koostumuksia ja menetelmiä näytteiden identifioinnin parantamiseksi indeksoiduissa nukleiinihappokirjastoissa
JP2015156872A5 (de)
RU2019138698A (ru) Способы и композиции для днк-профилирования
DE602005027067D1 (de) Nachweis chromosomaler störungen
WO2007118147A3 (en) Competitive oligonucleotides
IL190501A0 (en) Multicomponent nucleic acid enzymes and methods for their use
WO2006126040A8 (en) Bacterial and bacterial associated mirnas and uses thereof
WO2007130519A3 (en) Viral nucleic acid microarray and method of use
JP2014204730A5 (de)
ATE542922T1 (de) 2'-terminator-assoziierte pyrophosphorolyse- aktivierte polymerisierung
WO2007041342A3 (en) Labeled nucleotide analogs and uses therefor
JP2015511818A5 (de)
ATE518948T1 (de) Verbesserte polymerasen
JP2012514451A5 (de)
WO2006089238A3 (en) Multiplex assays for inferring ancestry
BRPI0816047A2 (pt) conjunto de oligonucleotídeos para detecção de um ácido nucleico alvo, métodos para detecção da presença ou ausência de um ácido nucleico alvo e de pelo menos dois ácidos nucleicos alvo, kit, mistura de reação e amplicon identificado por fluorescência
ATE272722T1 (de) Verfahren zur kontrollierbaren durchführung komplexer pcr-amplifikationen
WO2008061311A3 (en) Improved hybridisation of nucleic acids
Al-Madhagi et al. Isothermal amplification using modified primers for rapid electrochemical analysis of coeliac disease associated DQB1* 02 HLA allele
NZ585057A (en) Method of pooling samples for performing a biological assay
WO2005045059A3 (en) Allele assignment and probe selection in multiplexed assays of polymorphic targets
WO2005026389A3 (en) Ligation-based method of analysis of single nucleotide polymorphisms on genomic dna
WO2008119046A3 (en) Methods and compositions for multiplexing detection of nucleic acid sequences within an array element
DE60201441D1 (de) Verfahren zur analyse der dna-methylierung unter verwendung von fluoreszenzpolarisation

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 2217719

Country of ref document: EP