ATE518948T1 - Verbesserte polymerasen - Google Patents
Verbesserte polymerasenInfo
- Publication number
- ATE518948T1 ATE518948T1 AT06727060T AT06727060T ATE518948T1 AT E518948 T1 ATE518948 T1 AT E518948T1 AT 06727060 T AT06727060 T AT 06727060T AT 06727060 T AT06727060 T AT 06727060T AT E518948 T1 ATE518948 T1 AT E518948T1
- Authority
- AT
- Austria
- Prior art keywords
- dna
- polymerases
- polymerase
- modified
- reaction cycle
- Prior art date
Links
- 238000001712 DNA sequencing Methods 0.000 abstract 1
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 abstract 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 abstract 1
- 238000003491 array Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
Landscapes
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0509508A GB0509508D0 (en) | 2005-05-10 | 2005-05-10 | Improved polymerases |
| US75799706P | 2006-01-11 | 2006-01-11 | |
| PCT/GB2006/001700 WO2006120433A1 (en) | 2005-05-10 | 2006-05-10 | Improved polymerases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE518948T1 true ATE518948T1 (de) | 2011-08-15 |
Family
ID=34685371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06727060T ATE518948T1 (de) | 2005-05-10 | 2006-05-10 | Verbesserte polymerasen |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN101180390B (de) |
| AT (1) | ATE518948T1 (de) |
| GB (1) | GB0509508D0 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110318748A1 (en) * | 2010-02-26 | 2011-12-29 | Life Technologies Corporation | Modified Proteins and Methods of Making and Using Same |
| WO2013023176A2 (en) * | 2011-08-10 | 2013-02-14 | Life Technologies Corporation | Polymerase compositions, methods of making and using same |
| US11208636B2 (en) | 2011-08-10 | 2021-12-28 | Life Technologies Corporation | Polymerase compositions, methods of making and using same |
| US9758773B2 (en) * | 2014-02-14 | 2017-09-12 | Agilent Technologies, Inc. | Thermostable type-A DNA polymerase mutant with increased resistance to inhibitors in blood |
| ES2788949T3 (es) * | 2014-06-27 | 2020-10-23 | Illumina Inc | Polimerasas modificadas para la incorporación mejorada de análogos de nucleótidos |
| EP3201355B1 (de) * | 2014-09-30 | 2019-07-31 | Illumina, Inc. | Modifizierte polymerasen zur verbesserten inkorporation von nukleotidanaloga |
| ES2804843T3 (es) * | 2015-02-02 | 2021-02-09 | Hoffmann La Roche | Variantes de polimerasa |
| US10526588B2 (en) | 2015-05-14 | 2020-01-07 | Roche Sequencing Solutions, Inc. | Polymerase variants and uses thereof |
| JP2018530320A (ja) * | 2015-09-09 | 2018-10-18 | キアゲン ゲーエムベーハー | ポリメラーゼ酵素 |
| CN110573616B (zh) * | 2017-04-18 | 2023-09-05 | 深圳华大智造科技股份有限公司 | Phi29 DNA聚合酶及其编码基因与应用 |
| CN108795900B (zh) * | 2017-04-27 | 2021-02-02 | 深圳华大智造科技股份有限公司 | Dna聚合酶及其制备方法 |
| EP3768832B1 (de) * | 2018-03-21 | 2023-11-29 | F. Hoffmann-La Roche AG | Dna-polymerasen zum effizienten und effektiven einbau von methylierten dntps |
| CN109022387B (zh) * | 2018-08-29 | 2020-12-22 | 华南理工大学 | 一种突变型Pfu DNA聚合酶及其制备方法和应用 |
| KR20210098844A (ko) | 2018-12-05 | 2021-08-11 | 일루미나, 인코포레이티드 | 중합효소, 조성물, 및 사용 방법 |
| US20220340887A1 (en) * | 2019-09-18 | 2022-10-27 | SequLITE Genomics US, Inc. | Polymerases |
| US12077789B2 (en) | 2021-08-14 | 2024-09-03 | Illumina, Inc. | Polymerases, compositions, and methods of use |
| CN116286720A (zh) * | 2023-03-29 | 2023-06-23 | 赛纳生物科技(北京)有限公司 | 一种dna聚合酶 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7057026B2 (en) * | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| ES2864086T3 (es) * | 2002-08-23 | 2021-10-13 | Illumina Cambridge Ltd | Nucleótidos etiquetados |
| GB0321306D0 (en) * | 2003-09-11 | 2003-10-15 | Solexa Ltd | Modified polymerases for improved incorporation of nucleotide analogues |
-
2005
- 2005-05-10 GB GB0509508A patent/GB0509508D0/en not_active Ceased
-
2006
- 2006-05-10 AT AT06727060T patent/ATE518948T1/de not_active IP Right Cessation
- 2006-05-10 CN CN200680016045.1A patent/CN101180390B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101180390A (zh) | 2008-05-14 |
| GB0509508D0 (en) | 2005-06-15 |
| CN101180390B (zh) | 2013-04-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |