PL3102704T3 - Sondy oparte na oligonukleotydach i sposoby wykrywania drobnoustrojów - Google Patents
Sondy oparte na oligonukleotydach i sposoby wykrywania drobnoustrojówInfo
- Publication number
- PL3102704T3 PL3102704T3 PL15746286T PL15746286T PL3102704T3 PL 3102704 T3 PL3102704 T3 PL 3102704T3 PL 15746286 T PL15746286 T PL 15746286T PL 15746286 T PL15746286 T PL 15746286T PL 3102704 T3 PL3102704 T3 PL 3102704T3
- Authority
- PL
- Poland
- Prior art keywords
- microbes
- oligonucleotide
- detection
- methods
- based probes
- Prior art date
Links
- 108091034117 Oligonucleotide Proteins 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000523 sample Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0054—Macromolecular compounds, i.e. oligomers, polymers, dendrimers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6432—Quenching
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Optics & Photonics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461937359P | 2014-02-07 | 2014-02-07 | |
| US201461980498P | 2014-04-16 | 2014-04-16 | |
| US201461992034P | 2014-05-12 | 2014-05-12 | |
| PCT/US2015/015062 WO2015120406A1 (en) | 2014-02-07 | 2015-02-09 | Oligonucleotide-based probes and methods for detection of microbes |
| EP15746286.2A EP3102704B1 (en) | 2014-02-07 | 2015-02-09 | Oligonucleotide-based probes and methods for detection of microbes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3102704T3 true PL3102704T3 (pl) | 2021-01-11 |
Family
ID=53778521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL15746286T PL3102704T3 (pl) | 2014-02-07 | 2015-02-09 | Sondy oparte na oligonukleotydach i sposoby wykrywania drobnoustrojów |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US10619219B2 (pl) |
| EP (2) | EP3102704B1 (pl) |
| CA (1) | CA2939124C (pl) |
| PL (1) | PL3102704T3 (pl) |
| WO (1) | WO2015120406A1 (pl) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3102704T3 (pl) * | 2014-02-07 | 2021-01-11 | University Of Iowa Research Foundation | Sondy oparte na oligonukleotydach i sposoby wykrywania drobnoustrojów |
| US10663459B2 (en) | 2015-04-08 | 2020-05-26 | Haesung Bio Co., Ltd. | Composition for detecting microbial contamination comprising preparation for detecting nucleases, and use thereof |
| WO2016172701A2 (en) * | 2015-04-24 | 2016-10-27 | University Of Iowa Research Foundation | Oligonucleotide-based probes for detection of circulating tumor cell nucleases |
| CN106636409A (zh) * | 2016-12-28 | 2017-05-10 | 健路生物科技(苏州)有限公司 | 一种通用荧光探针及其检测方法和应用 |
| EP3596228B1 (en) * | 2017-03-14 | 2022-09-28 | Tubitak | Method for rapid identification of microorganisms producing nuclease enzymes |
| WO2018182510A1 (en) * | 2017-03-28 | 2018-10-04 | Agency For Science, Technology And Research | Nanomaterial-based bacterial sensors |
| WO2019043187A1 (en) * | 2017-08-31 | 2019-03-07 | Somaprobes Sl | SIDE FLOW ASSAY FOR DETECTING THE PRESENCE OF A MAMMALIAN CELL OR SPECIFIC BACTERIUM IN A BIOLOGICAL SAMPLE |
| US12378591B2 (en) | 2017-09-29 | 2025-08-05 | University Of Iowa Research Foundation | Digital nuclease detection compositions and methods |
| JPWO2019112028A1 (ja) * | 2017-12-08 | 2020-11-26 | テルモ株式会社 | マイコプラズマの有無の検査方法 |
| ES2976491T3 (es) * | 2018-05-24 | 2024-08-02 | Philipps Univ Marburg | Colorantes de cianina y su uso para la tinción in vivo de microorganismos |
| WO2021092110A1 (en) * | 2019-11-05 | 2021-05-14 | Nuclease Probe Technologies, Inc. | Microbial detection platform |
| JP7387524B2 (ja) * | 2020-04-06 | 2023-11-28 | Tianma Japan株式会社 | 蛍光を用いた免疫分析法で測定するための試料溶液の調製方法、測定用セル、測定キットおよび試料溶液の調製装置 |
| JP2023542867A (ja) | 2020-09-11 | 2023-10-12 | グリンプス バイオ, インコーポレイテッド | 疾患の検出/診断、病期分類、モニタリング及び処置のための生体外でのプロテアーゼ活性検出 |
| EP4000635A1 (en) * | 2020-11-16 | 2022-05-25 | Frank J. Hernandez | Therapeutic-oligonucleotides activated by nucleases |
| US20220315991A1 (en) * | 2021-03-31 | 2022-10-06 | Neogen Corporation | Detecting Salmonella from an Environmental Sample |
| US20230096750A1 (en) | 2021-08-20 | 2023-03-30 | Philipps-Universität Marburg | Cyanine dyes and their usage for in vivo staining of microorganisms and other living cells |
| WO2023086970A2 (en) * | 2021-11-12 | 2023-05-19 | Arna Genomics Us Incorporated | Methods and compositions for analyzing nucleic acids and nucleases in a body fluid as indicators of disease |
| WO2023140228A1 (ja) * | 2022-01-18 | 2023-07-27 | 国立大学法人東北大学 | タンパク質の変性状態又は凝集状態を可視化する方法 |
| CN114441745B (zh) * | 2022-02-09 | 2025-01-28 | 广东省科学院生态环境与土壤研究所 | 分子逻辑门智能化检测真菌毒素新方法 |
| CN117969470B (zh) | 2023-12-26 | 2024-07-16 | 中国人民解放军军事科学院军事医学研究院 | 一种相思子毒素的快速检测方法 |
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| US3770631A (en) * | 1971-06-29 | 1973-11-06 | Baxter Laboratories Inc | Clarification of blood serum and plasma |
| US6041910A (en) | 1997-09-22 | 2000-03-28 | Jervis B. Webb Company | Baggage pusher device and system |
| US20060270624A1 (en) | 1991-12-24 | 2006-11-30 | Isis Pharmaceuticals, Inc. | Gapped 2' modified oligonucleotides |
| US5538848A (en) * | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| US5656430A (en) * | 1995-06-07 | 1997-08-12 | Trevigen, Inc. | Oscillating signal amplifier for nucleic acid detection |
| CA2271713A1 (en) | 1996-11-13 | 1998-05-22 | Sagami Chemical Research Center | Human proteins having transmembrane domains and dnas encoding these proteins |
| US5914245A (en) * | 1998-04-20 | 1999-06-22 | Kairos Scientific Inc. | Solid phase enzyme kinetics screening in microcolonies |
| US7041807B1 (en) * | 1999-06-23 | 2006-05-09 | Caprion Pharmaceuticals, Inc. | Antibodies to a YYX epitope of a mammalian prion protein |
| DE60044977D1 (de) * | 1999-09-24 | 2010-10-28 | Ambion Inc | Cocktail von nukleaseinhibitoren |
| US6773885B1 (en) | 2000-09-29 | 2004-08-10 | Integrated Dna Technologies, Inc. | Compositions and methods for visual ribonuclease detection assays |
| DE10215238C1 (de) * | 2002-04-06 | 2003-08-14 | Cytonet Gmbh & Co Kg | Nachweis von Mykobakterien in klinischem Material |
| US20030190626A1 (en) | 2002-04-09 | 2003-10-09 | Vasulinga Ravikumar | Phosphorothioate monoester modified oligomers |
| AU2003275018B2 (en) | 2002-09-20 | 2009-10-01 | Integrated Dna Technologies, Inc. | Anthraquinone quencher dyes, their methods of preparation and use |
| AU2003284636A1 (en) | 2002-11-22 | 2004-06-18 | Daiichi Pure Chemicals Co., Ltd. | Method of inspecting staphylococcus aureus |
| US7439341B2 (en) | 2003-11-14 | 2008-10-21 | Integrated Dna Technologies, Inc. | Fluorescence quenching azo dyes, their methods of preparation and use |
| WO2005078139A2 (en) | 2004-02-09 | 2005-08-25 | Thomas Jefferson University | DIAGNOSIS AND TREATMENT OF CANCERS WITH MicroRNA LOCATED IN OR NEAR CANCER-ASSOCIATED CHROMOSOMAL FEATURES |
| ES2321845T3 (es) | 2004-06-29 | 2009-06-12 | F. Hoffmann-La Roche Ag | Asociacion de polimorfismos de nucleotidos individuales en el ppar gamma, con la osteoporosis. |
| WO2006127507A2 (en) | 2005-05-20 | 2006-11-30 | Integrated Dna Technologies, Inc. | Compounds and methods for labeling oligonucleotides |
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| DE602006020618D1 (de) * | 2005-12-22 | 2011-04-21 | Visen Medical Inc | Kombiniertes röntgen- und optisches tomographie-bildgebungssystem |
| ATE516371T1 (de) * | 2007-10-22 | 2011-07-15 | Lgc Ltd | Oligonukleotide und deren verwendungen |
| DK2644707T3 (en) * | 2008-04-30 | 2015-06-29 | Integrated Dna Tech Inc | RNase-H-based assays using modified RNA monomers. |
| WO2014143228A1 (en) * | 2013-03-15 | 2014-09-18 | Integrated Dna Technologies, Inc. | Rnase h-based assays utilizing modified rna monomers |
| EP2329006A1 (en) | 2008-08-21 | 2011-06-08 | 3M Innovative Properties Company | Methods and compositions for enumerating antibiotic-resistant microorganisms |
| CN102301005A (zh) * | 2008-12-17 | 2011-12-28 | 生命技术公司 | 用于检测等位基因变体的方法、组合物和试剂盒 |
| US20100323348A1 (en) * | 2009-01-31 | 2010-12-23 | The Regents Of The University Of Colorado, A Body Corporate | Methods and Compositions for Using Error-Detecting and/or Error-Correcting Barcodes in Nucleic Acid Amplification Process |
| BRPI1005946A2 (pt) | 2009-02-26 | 2019-09-24 | 3M Innovative Properties Co | métodos para detectar um microorganismo e para detectar atividade desoxirribonuclease, artigo de detecção e kit |
| EP2408936A4 (en) * | 2009-03-18 | 2013-01-30 | Sequenom Inc | USE OF HEAT-STAINED ENDONUCLEASES FOR THE PREPARATION OF REPORTER MOLECULES |
| DK2446033T3 (da) | 2009-06-22 | 2014-01-27 | Univ Strasbourg | Fremgangsmåde til fremstilling af et addukt |
| EP2504453A4 (en) | 2009-11-23 | 2013-07-17 | Becton Dickinson Co | ASSAY METHOD FOR TARGET NUCLEIC ACID BY SIGNAL AMPLIFICATION USING HYBRIDIZATION AND RESTRICTION OF PROBES |
| EP2558596B1 (en) | 2010-04-16 | 2018-03-14 | The Government Of The United States Of America As Reresented By The Secretary Of The Department Of Health & Human Services | Real time pcr assay for detection of bacterial respiratory pathogens |
| EP2658985A1 (en) * | 2010-12-30 | 2013-11-06 | E.I. Du Pont De Nemours And Company | Increased oil content by increasing yap1 transcription factor activity in oleaginous yeasts |
| WO2012102260A1 (ja) * | 2011-01-26 | 2012-08-02 | オリンパス株式会社 | 核酸分子の多型識別方法 |
| DK2714939T3 (en) * | 2011-05-24 | 2015-06-29 | Elitech Holding Bv | DETECTION OF METHICILLIN-RESISTENT STAPHYLOCOCCUS AUREUS |
| WO2013033436A1 (en) * | 2011-09-01 | 2013-03-07 | University Of Iowa Research Foundation | Oligonucleotide-based probes for detection of bacterial nucleases |
| WO2013040992A1 (zh) | 2011-09-20 | 2013-03-28 | 苏州瑞博生物技术有限公司 | 一种双链核酸及其在核糖核酸酶检测中的应用和试剂盒 |
| US20140017716A1 (en) * | 2012-07-11 | 2014-01-16 | Siscapa Assay Technologies, Inc. | Proteolytic digestion kit with dried reagents |
| DE102013225037B4 (de) | 2013-12-05 | 2016-08-25 | Asklepios Kliniken Verwaltungsgesellschaft mbH | Verfahren zur Erkennung resistenter Keime und Vorrichtung zum Durchführen desselben |
| PL3102704T3 (pl) * | 2014-02-07 | 2021-01-11 | University Of Iowa Research Foundation | Sondy oparte na oligonukleotydach i sposoby wykrywania drobnoustrojów |
| US10635800B2 (en) * | 2016-06-07 | 2020-04-28 | Vocalzoom Systems Ltd. | System, device, and method of voice-based user authentication utilizing a challenge |
| EP3596228B1 (en) | 2017-03-14 | 2022-09-28 | Tubitak | Method for rapid identification of microorganisms producing nuclease enzymes |
| WO2019070612A1 (en) | 2017-10-02 | 2019-04-11 | Quidel Corporation | PHAGE-BASED DETECTION METHOD FOR ANTIMICROBIAL SUSCEPTIBILITY TESTING AND IDENTIFICATION OF BACTERIAL SPECIES |
| KR102264434B1 (ko) | 2018-11-26 | 2021-06-14 | 재단법인 바이오나노헬스가드연구단 | 황색포도상구균-특이 핵산 프로브 및 이의 용도 |
-
2015
- 2015-02-09 PL PL15746286T patent/PL3102704T3/pl unknown
- 2015-02-09 EP EP15746286.2A patent/EP3102704B1/en active Active
- 2015-02-09 US US15/117,414 patent/US10619219B2/en active Active
- 2015-02-09 EP EP20156119.8A patent/EP3680348B1/en active Active
- 2015-02-09 CA CA2939124A patent/CA2939124C/en active Active
- 2015-02-09 WO PCT/US2015/015062 patent/WO2015120406A1/en not_active Ceased
-
2020
- 2020-02-19 US US16/794,677 patent/US11155882B2/en active Active
-
2021
- 2021-10-05 US US17/494,626 patent/US12378612B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3102704A1 (en) | 2016-12-14 |
| EP3680348A1 (en) | 2020-07-15 |
| US12378612B2 (en) | 2025-08-05 |
| CA2939124A1 (en) | 2015-08-13 |
| US20220098648A1 (en) | 2022-03-31 |
| EP3680348B1 (en) | 2023-04-12 |
| WO2015120406A1 (en) | 2015-08-13 |
| EP3102704A4 (en) | 2017-09-20 |
| US20200283830A1 (en) | 2020-09-10 |
| CA2939124C (en) | 2023-08-29 |
| EP3102704B1 (en) | 2020-02-12 |
| US11155882B2 (en) | 2021-10-26 |
| US10619219B2 (en) | 2020-04-14 |
| US20160340717A1 (en) | 2016-11-24 |
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