JP2017536813A5 - - Google Patents
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- JP2017536813A5 JP2017536813A5 JP2017521095A JP2017521095A JP2017536813A5 JP 2017536813 A5 JP2017536813 A5 JP 2017536813A5 JP 2017521095 A JP2017521095 A JP 2017521095A JP 2017521095 A JP2017521095 A JP 2017521095A JP 2017536813 A5 JP2017536813 A5 JP 2017536813A5
- Authority
- JP
- Japan
- Prior art keywords
- primer
- virus
- reverse
- cdna
- forward primer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000000523 sample Substances 0.000 claims 24
- 238000000034 method Methods 0.000 claims 19
- 108091033319 polynucleotide Proteins 0.000 claims 15
- 239000002157 polynucleotide Substances 0.000 claims 15
- 102000040430 polynucleotide Human genes 0.000 claims 15
- 239000002299 complementary DNA Substances 0.000 claims 13
- 238000001514 detection method Methods 0.000 claims 13
- 102000004190 Enzymes Human genes 0.000 claims 10
- 108090000790 Enzymes Proteins 0.000 claims 10
- 102000004594 DNA Polymerase I Human genes 0.000 claims 9
- 108010017826 DNA Polymerase I Proteins 0.000 claims 9
- 102100034343 Integrase Human genes 0.000 claims 9
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 claims 9
- 241001493065 dsRNA viruses Species 0.000 claims 8
- 108091093088 Amplicon Proteins 0.000 claims 7
- 230000003321 amplification Effects 0.000 claims 6
- 238000006073 displacement reaction Methods 0.000 claims 6
- 238000003199 nucleic acid amplification method Methods 0.000 claims 6
- 241000725619 Dengue virus Species 0.000 claims 5
- 238000006243 chemical reaction Methods 0.000 claims 5
- 230000003612 virological effect Effects 0.000 claims 5
- 108020005187 Oligonucleotide Probes Proteins 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 4
- 238000011901 isothermal amplification Methods 0.000 claims 4
- 239000002751 oligonucleotide probe Substances 0.000 claims 4
- 241000713196 Influenza B virus Species 0.000 claims 3
- 238000010804 cDNA synthesis Methods 0.000 claims 3
- 230000000087 stabilizing effect Effects 0.000 claims 3
- 241000712891 Arenavirus Species 0.000 claims 2
- 241000710780 Bovine viral diarrhea virus 1 Species 0.000 claims 2
- 241001115402 Ebolavirus Species 0.000 claims 2
- 241000710831 Flavivirus Species 0.000 claims 2
- 241000712902 Lassa mammarenavirus Species 0.000 claims 2
- 208000009341 RNA Virus Infections Diseases 0.000 claims 2
- 241000580858 Simian-Human immunodeficiency virus Species 0.000 claims 2
- 241000710886 West Nile virus Species 0.000 claims 2
- 241000710772 Yellow fever virus Species 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 2
- 230000015556 catabolic process Effects 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 238000006731 degradation reaction Methods 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 241000712461 unidentified influenza virus Species 0.000 claims 2
- 229940051021 yellow-fever virus Drugs 0.000 claims 2
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 claims 1
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 claims 1
- 241000711549 Hepacivirus C Species 0.000 claims 1
- 208000005176 Hepatitis C Diseases 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- 230000009089 cytolysis Effects 0.000 claims 1
- 230000007613 environmental effect Effects 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 125000000250 methylamino group Chemical group [H]N(*)C([H])([H])[H] 0.000 claims 1
- UFEJKYYYVXYMMS-UHFFFAOYSA-N methylcarbamic acid Chemical compound CNC(O)=O UFEJKYYYVXYMMS-UHFFFAOYSA-N 0.000 claims 1
- 238000010839 reverse transcription Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462066277P | 2014-10-20 | 2014-10-20 | |
| US62/066,277 | 2014-10-20 | ||
| US201562104008P | 2015-01-15 | 2015-01-15 | |
| US62/104,008 | 2015-01-15 | ||
| PCT/US2015/056491 WO2016064894A2 (en) | 2014-10-20 | 2015-10-20 | Compositions and methods for detecting an rna virus |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020189107A Division JP7114676B2 (ja) | 2014-10-20 | 2020-11-13 | Ｒｎａウイルスを検出するための組成物及び方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017536813A JP2017536813A (ja) | 2017-12-14 |
| JP2017536813A5 true JP2017536813A5 (enExample) | 2018-12-06 |
Family
ID=55761744
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017521095A Pending JP2017536813A (ja) | 2014-10-20 | 2015-10-20 | Ｒｎａウイルスを検出するための組成物及び方法 |
| JP2020189107A Active JP7114676B2 (ja) | 2014-10-20 | 2020-11-13 | Ｒｎａウイルスを検出するための組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020189107A Active JP7114676B2 (ja) | 2014-10-20 | 2020-11-13 | Ｒｎａウイルスを検出するための組成物及び方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10793922B2 (enExample) |
| EP (2) | EP4141128A1 (enExample) |
| JP (2) | JP2017536813A (enExample) |
| CN (1) | CN107208137A (enExample) |
| AU (2) | AU2015336086C1 (enExample) |
| BR (1) | BR112017008082A2 (enExample) |
| CA (1) | CA2965137A1 (enExample) |
| MX (1) | MX2017005159A (enExample) |
| WO (1) | WO2016064894A2 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012021493A2 (en) | 2010-08-13 | 2012-02-16 | Envirologix Inc. | Compositions and methods for quantifying a nucleic acid sequence in a sample |
| EP2734621B1 (en) | 2011-07-22 | 2019-09-04 | President and Fellows of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| KR102048946B1 (ko) | 2012-04-09 | 2019-11-27 | 엔바이로로직스 인크. | 시료 내 핵산 서열을 정량화하기 위한 조성물 및 방법 |
| US20150044192A1 (en) | 2013-08-09 | 2015-02-12 | President And Fellows Of Harvard College | Methods for identifying a target site of a cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US9388430B2 (en) | 2013-09-06 | 2016-07-12 | President And Fellows Of Harvard College | Cas9-recombinase fusion proteins and uses thereof |
| US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
| US11053481B2 (en) | 2013-12-12 | 2021-07-06 | President And Fellows Of Harvard College | Fusions of Cas9 domains and nucleic acid-editing domains |
| UA123387C2 (uk) * | 2014-04-22 | 2021-03-31 | Інвайролоджикс, Інк. | Виділений праймерний олігонуклеотид та спосіб його застосування |
| WO2016022363A2 (en) | 2014-07-30 | 2016-02-11 | President And Fellows Of Harvard College | Cas9 proteins including ligand-dependent inteins |
| CN107208137A (zh) | 2014-10-20 | 2017-09-26 | 龙公司 | 检测rna病毒的组合物和方法 |
| IL294014B2 (en) | 2015-10-23 | 2024-07-01 | Harvard College | Nucleobase editors and uses thereof |
| WO2018013579A1 (en) * | 2016-07-11 | 2018-01-18 | cARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | Sweat as a biofluid for analysis and disease identification |
| WO2018027078A1 (en) | 2016-08-03 | 2018-02-08 | President And Fellows Of Harard College | Adenosine nucleobase editors and uses thereof |
| CN109804066A (zh) | 2016-08-09 | 2019-05-24 | 哈佛大学的校长及成员们 | 可编程cas9-重组酶融合蛋白及其用途 |
| WO2018039438A1 (en) | 2016-08-24 | 2018-03-01 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| CN110214180A (zh) | 2016-10-14 | 2019-09-06 | 哈佛大学的校长及成员们 | 核碱基编辑器的aav递送 |
| US10745677B2 (en) | 2016-12-23 | 2020-08-18 | President And Fellows Of Harvard College | Editing of CCR5 receptor gene to protect against HIV infection |
| WO2018165631A1 (en) | 2017-03-09 | 2018-09-13 | President And Fellows Of Harvard College | Cancer vaccine |
| WO2018165504A1 (en) | 2017-03-09 | 2018-09-13 | President And Fellows Of Harvard College | Suppression of pain by gene editing |
| JP2020510439A (ja) | 2017-03-10 | 2020-04-09 | プレジデント アンド フェローズ オブ ハーバード カレッジ | シトシンからグアニンへの塩基編集因子 |
| EP3596218B1 (en) * | 2017-03-15 | 2023-08-23 | The Broad Institute, Inc. | Crispr effector system based diagnostics for virus detection |
| KR20240116572A (ko) | 2017-03-23 | 2024-07-29 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 핵산 프로그램가능한 dna 결합 단백질을 포함하는 핵염기 편집제 |
| US11560566B2 (en) | 2017-05-12 | 2023-01-24 | President And Fellows Of Harvard College | Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation |
| CN111801345A (zh) | 2017-07-28 | 2020-10-20 | 哈佛大学的校长及成员们 | 使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物 |
| US11319532B2 (en) | 2017-08-30 | 2022-05-03 | President And Fellows Of Harvard College | High efficiency base editors comprising Gam |
| CN111757937A (zh) | 2017-10-16 | 2020-10-09 | 布罗德研究所股份有限公司 | 腺苷碱基编辑器的用途 |
| US12406749B2 (en) | 2017-12-15 | 2025-09-02 | The Broad Institute, Inc. | Systems and methods for predicting repair outcomes in genetic engineering |
| CN108588050B (zh) * | 2018-05-14 | 2021-06-25 | 北京艾克伦医疗科技有限公司 | Dna聚合酶以及核酸检测方法和试剂盒 |
| WO2019226953A1 (en) | 2018-05-23 | 2019-11-28 | The Broad Institute, Inc. | Base editors and uses thereof |
| EP3820495A4 (en) | 2018-07-09 | 2022-07-20 | The Broad Institute Inc. | RNA-PROGRAMMABLE EPIGENETIC RNA MODIFIERS AND THEIR USES |
| US12281338B2 (en) | 2018-10-29 | 2025-04-22 | The Broad Institute, Inc. | Nucleobase editors comprising GeoCas9 and uses thereof |
| CN109593863A (zh) * | 2018-11-28 | 2019-04-09 | 江南大学 | 一种链置换型dna聚合酶诱导等温循环扩增反应检测肉类来源的方法 |
| US12351837B2 (en) | 2019-01-23 | 2025-07-08 | The Broad Institute, Inc. | Supernegatively charged proteins and uses thereof |
| JP7602238B2 (ja) | 2019-03-07 | 2024-12-18 | 国立大学法人 長崎大学 | Ｔｅｒｔプロモーター変異を検出するプローブセット |
| CA3130488A1 (en) | 2019-03-19 | 2020-09-24 | David R. Liu | Methods and compositions for editing nucleotide sequences |
| US12473543B2 (en) | 2019-04-17 | 2025-11-18 | The Broad Institute, Inc. | Adenine base editors with reduced off-target effects |
| US12435330B2 (en) | 2019-10-10 | 2025-10-07 | The Broad Institute, Inc. | Methods and compositions for prime editing RNA |
| CN111424116B (zh) * | 2020-03-19 | 2023-06-23 | 首都儿科研究所 | 用于检测黄热病毒疫苗株的rt-lamp试剂盒及其专用引物和应用 |
| CN111334610B (zh) * | 2020-03-20 | 2023-11-14 | 广东省妇幼保健院 | 一种登革病毒通用型rt-raa-lfd扩增引物及检测方法 |
| CN111471797B (zh) * | 2020-04-16 | 2023-05-12 | 广东省实验动物监测所 | 用于检测猫冠状病毒的rt-rpa引物对、探针、试剂盒及检测方法 |
| WO2021226558A1 (en) | 2020-05-08 | 2021-11-11 | The Broad Institute, Inc. | Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence |
| WO2022011215A1 (en) * | 2020-07-10 | 2022-01-13 | The Rockefeller University | Method and system for saliva testing for virus including covid-19 |
| JP2022060807A (ja) * | 2020-10-05 | 2022-04-15 | キヤノンメディカルシステムズ株式会社 | 乾燥試薬、試薬キット、乾燥試薬の製造方法、分析方法及び核酸増幅方法 |
| EP4669769A1 (en) * | 2023-02-14 | 2025-12-31 | Ador Diagnostics Ltd | Rolling circle amplification based on an amplicon |
| CN116574844B (zh) * | 2023-03-01 | 2024-02-27 | 宁夏大学 | 一组检测牛病毒性腹泻病毒的rpa引物对、试剂盒和检测方法 |
Family Cites Families (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
| US6090555A (en) | 1997-12-11 | 2000-07-18 | Affymetrix, Inc. | Scanned image alignment systems and methods |
| US5571639A (en) | 1994-05-24 | 1996-11-05 | Affymax Technologies N.V. | Computer-aided engineering system for design of sequence arrays and lithographic masks |
| US6593086B2 (en) * | 1996-05-20 | 2003-07-15 | Mount Sinai School Of Medicine Of New York University | Nucleic acid amplification methods |
| US5795716A (en) | 1994-10-21 | 1998-08-18 | Chee; Mark S. | Computer-aided visualization and analysis system for sequence evaluation |
| US5629179A (en) | 1995-03-17 | 1997-05-13 | Novagen, Inc. | Method and kit for making CDNA library |
| US5733729A (en) | 1995-09-14 | 1998-03-31 | Affymetrix, Inc. | Computer-aided probability base calling for arrays of nucleic acid probes on chips |
| JP2000505312A (ja) | 1996-03-18 | 2000-05-09 | モレキュラー バイオロジー リソーシーズ，インコーポレイテッド | 標的核酸配列増幅 |
| US6130038A (en) | 1996-07-16 | 2000-10-10 | Gen-Probe Incorporated | Method for amplifying target nucleic acids using modified primers |
| US6117634A (en) * | 1997-03-05 | 2000-09-12 | The Reagents Of The University Of Michigan | Nucleic acid sequencing and mapping |
| US6586806B1 (en) | 1997-06-20 | 2003-07-01 | Cypress Semiconductor Corporation | Method and structure for a single-sided non-self-aligned transistor |
| US6229911B1 (en) | 1997-07-25 | 2001-05-08 | Affymetrix, Inc. | Method and apparatus for providing a bioinformatics database |
| GB9716231D0 (en) | 1997-07-31 | 1997-10-08 | Amersham Int Ltd | Base analogues |
| ATE280246T1 (de) | 1997-08-15 | 2004-11-15 | Affymetrix Inc | Polymorphismuserkennung mit hilfe cluster-analyse |
| US6355421B1 (en) | 1997-10-27 | 2002-03-12 | Boston Probes, Inc. | Methods, kits and compositions pertaining to PNA molecular beacons |
| US5952202A (en) | 1998-03-26 | 1999-09-14 | The Perkin Elmer Corporation | Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification |
| JP3565025B2 (ja) | 1998-07-07 | 2004-09-15 | 日産自動車株式会社 | 治具交換装置および治具交換方法 |
| US6185561B1 (en) | 1998-09-17 | 2001-02-06 | Affymetrix, Inc. | Method and apparatus for providing and expression data mining database |
| WO2000070095A2 (en) * | 1999-05-17 | 2000-11-23 | Dade Behring Inc. | Homogeneous isothermal amplification and detection of nucleic acids using a template switch oligonucleotide |
| US6436677B1 (en) | 2000-03-02 | 2002-08-20 | Promega Corporation | Method of reverse transcription |
| ATE312942T1 (de) | 2000-10-25 | 2005-12-15 | Hoffmann La Roche | Amplifizierung unter verwendung von modifizierten primern |
| JP2004532615A (ja) | 2000-12-27 | 2004-10-28 | インヴィトロジェン コーポレーション | 核酸の検出および識別のためのプライマーおよび方法 |
| US20020183936A1 (en) | 2001-01-24 | 2002-12-05 | Affymetrix, Inc. | Method, system, and computer software for providing a genomic web portal |
| WO2004022701A2 (en) | 2001-07-15 | 2004-03-18 | Keck Graduate Institute | Exponential amplification of nucleic acids using nicking agents |
| US7112423B2 (en) | 2001-07-15 | 2006-09-26 | Keck Graduate Institute | Nucleic acid amplification using nicking agents |
| US6585606B2 (en) | 2001-07-16 | 2003-07-01 | Thomas S. Penrose | Golf club accessory |
| WO2003016569A1 (en) | 2001-08-20 | 2003-02-27 | Takara Bio Inc. | Nucleic acid amplification methods |
| US6977148B2 (en) | 2001-10-15 | 2005-12-20 | Qiagen Gmbh | Multiple displacement amplification |
| US6617137B2 (en) | 2001-10-15 | 2003-09-09 | Molecular Staging Inc. | Method of amplifying whole genomes without subjecting the genome to denaturing conditions |
| US20030211483A1 (en) * | 2002-05-09 | 2003-11-13 | Schroeder Benjamin G. | Methods for the enrichment of low-abundance polynucleotides |
| US7662594B2 (en) * | 2002-09-20 | 2010-02-16 | New England Biolabs, Inc. | Helicase-dependent amplification of RNA |
| AU2003272438B2 (en) | 2002-09-20 | 2009-04-02 | New England Biolabs, Inc. | Helicase dependent amplification of nucleic acids |
| JP4380305B2 (ja) | 2003-11-21 | 2009-12-09 | 味の素株式会社 | 発酵法によるｌ−アミノ酸の製造法 |
| WO2005087952A1 (en) | 2004-03-05 | 2005-09-22 | The Regents Of The University Of California | Methods and compositions relating to the pharmacogenetics of abcc2, ugt1a1, and/or slc01b1 gene variants |
| US20060115838A1 (en) | 2004-10-19 | 2006-06-01 | Trevigen Inc. | Real-time detection of amplicons using nucleic acid repair enzymes |
| WO2006074162A2 (en) | 2005-01-04 | 2006-07-13 | Hitachi Chemical Company, Ltd. | Primer generation rolling circle amplification |
| CA2616241C (en) | 2005-07-25 | 2012-02-07 | Asm Scientific, Inc. | Methods for multiplexing recombinase polymerase amplification |
| EP1924704B1 (en) | 2005-08-02 | 2011-05-25 | Rubicon Genomics, Inc. | Compositions and methods for processing and amplification of dna, including using multiple enzymes in a single reaction |
| US8343738B2 (en) * | 2005-09-14 | 2013-01-01 | Human Genetic Signatures Pty. Ltd. | Assay for screening for potential cervical cancer |
| US7947286B2 (en) * | 2005-10-07 | 2011-05-24 | Panthera Biopharma Llc | Drosophila cell lines producing recombinant secretable filovirus surface glycoproteins lacking the membrane spanning domain |
| EP1951888B1 (en) * | 2005-11-09 | 2012-09-05 | PrimeraDx, Inc. | Multiplexed quantitative detection of pathogens |
| US8673567B2 (en) * | 2006-03-08 | 2014-03-18 | Atila Biosystems, Inc. | Method and kit for nucleic acid sequence detection |
| CN100489112C (zh) * | 2006-03-10 | 2009-05-20 | 杭州优思达生物技术有限公司 | 切口酶扩增靶核酸序列的方法及用于扩增靶核酸序列的试剂盒及其应用 |
| US20090092967A1 (en) | 2006-06-26 | 2009-04-09 | Epoch Biosciences, Inc. | Method for generating target nucleic acid sequences |
| WO2008042067A2 (en) | 2006-09-28 | 2008-04-10 | Illumina, Inc. | Compositions and methods for nucleotide sequencing |
| JP2010505396A (ja) * | 2006-10-06 | 2010-02-25 | ディーエヌエー ジェノテック インク | リボ核酸を抽出するための安定化組成物および方法 |
| JP2008136451A (ja) * | 2006-12-05 | 2008-06-19 | Hitachi Ltd | 核酸増幅法 |
| US20080254458A1 (en) | 2007-04-10 | 2008-10-16 | Asiagen Corporation | Method of pre-treating in pleural effusion for detection of Mycobacterium tuberculosis |
| US20080274458A1 (en) | 2007-05-01 | 2008-11-06 | Latham Gary J | Nucleic acid quantitation methods |
| US9689031B2 (en) | 2007-07-14 | 2017-06-27 | Ionian Technologies, Inc. | Nicking and extension amplification reaction for the exponential amplification of nucleic acids |
| US20090048439A1 (en) * | 2007-08-06 | 2009-02-19 | Weisburg William G | Isolation of nucleic acids molecules using modified solid supports |
| US20090197254A1 (en) | 2007-12-14 | 2009-08-06 | Ming-Chou Lee | Variant scorpion primers for nucleic acid amplification and detection |
| DK2279263T3 (da) | 2008-04-30 | 2013-11-11 | Integrated Dna Tech Inc | Rnase-h-baserede assays med anvendelse af modificerede rna-monomerer |
| EP2333109B1 (en) * | 2008-09-03 | 2013-08-07 | Takara Bio, Inc. | Composition for detection of rna |
| AU2010206492B2 (en) * | 2009-01-21 | 2012-07-12 | Human Genetic Signatures Pty Ltd | Improved isothermal strand displacement amplification |
| EP2408936A4 (en) | 2009-03-18 | 2013-01-30 | Sequenom Inc | USE OF HEAT-STAINED ENDONUCLEASES FOR THE PREPARATION OF REPORTER MOLECULES |
| WO2010126913A1 (en) | 2009-04-27 | 2010-11-04 | Gen-Probe Incorporated | Methods and kits for use in the selective amplification of target sequences |
| WO2012021493A2 (en) * | 2010-08-13 | 2012-02-16 | Envirologix Inc. | Compositions and methods for quantifying a nucleic acid sequence in a sample |
| EP2420579A1 (en) | 2010-08-17 | 2012-02-22 | QIAGEN GmbH | Helicase dependent isothermal amplification using nicking enzymes |
| CN103946398B (zh) * | 2011-09-15 | 2019-08-13 | 健能泰格技术公司 | 探针：反义探针组合物对高特异性dna或rna的检测 |
| WO2013101783A2 (en) * | 2011-12-30 | 2013-07-04 | Bio-Rad Laboratories, Inc. | Methods and compositions for performing nucleic acid amplification reactions |
| KR102048946B1 (ko) | 2012-04-09 | 2019-11-27 | 엔바이로로직스 인크. | 시료 내 핵산 서열을 정량화하기 위한 조성물 및 방법 |
| WO2014004852A2 (en) * | 2012-06-29 | 2014-01-03 | General Electric Company | Kit for isothermal dna amplification starting from an rna template |
| JP2014082936A (ja) * | 2012-10-19 | 2014-05-12 | Kyoto Univ | 変異型逆転写酵素 |
| UA123387C2 (uk) | 2014-04-22 | 2021-03-31 | Інвайролоджикс, Інк. | Виділений праймерний олігонуклеотид та спосіб його застосування |
| US10100370B2 (en) | 2014-04-30 | 2018-10-16 | Envirologix Inc. | Compositions and methods for detecting huanglongbing |
| CN107208137A (zh) | 2014-10-20 | 2017-09-26 | 龙公司 | 检测rna病毒的组合物和方法 |
| EP3212767A4 (en) | 2014-10-28 | 2018-09-26 | Envirologix Inc. | Sample preparation vessels, microfluidic circuits, and systems and methods for sample preparation, extraction, and analysis |
| CA2975236A1 (en) | 2015-01-30 | 2016-08-04 | Envirologix, Inc. | Compositions and methods for rapid detection of salmonella |
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2015
- 2015-10-20 CN CN201580069867.5A patent/CN107208137A/zh active Pending
- 2015-10-20 AU AU2015336086A patent/AU2015336086C1/en active Active
- 2015-10-20 MX MX2017005159A patent/MX2017005159A/es unknown
- 2015-10-20 WO PCT/US2015/056491 patent/WO2016064894A2/en not_active Ceased
- 2015-10-20 EP EP22187762.4A patent/EP4141128A1/en active Pending
- 2015-10-20 CA CA2965137A patent/CA2965137A1/en active Pending
- 2015-10-20 BR BR112017008082A patent/BR112017008082A2/pt unknown
- 2015-10-20 EP EP15852795.2A patent/EP3209802B1/en not_active Revoked
- 2015-10-20 US US15/520,328 patent/US10793922B2/en active Active
- 2015-10-20 JP JP2017521095A patent/JP2017536813A/ja active Pending
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2020
- 2020-08-12 US US16/991,216 patent/US12392001B2/en active Active
- 2020-11-13 JP JP2020189107A patent/JP7114676B2/ja active Active
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2021
- 2021-03-03 AU AU2021201378A patent/AU2021201378B2/en active Active
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