JP2017536813A - Ｒｎａウイルスを検出するための組成物及び方法 - Google Patents

Ｒｎａウイルスを検出するための組成物及び方法 Download PDF

Info

Publication number
JP2017536813A
JP2017536813A JP2017521095A JP2017521095A JP2017536813A JP 2017536813 A JP2017536813 A JP 2017536813A JP 2017521095 A JP2017521095 A JP 2017521095A JP 2017521095 A JP2017521095 A JP 2017521095A JP 2017536813 A JP2017536813 A JP 2017536813A
Authority
JP
Japan
Prior art keywords
primer
ebola virus
virus
sample
rna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2017521095A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017536813A5 (enExample
Inventor
ラーズ ピータース、
ラーズ ピータース、
スティーブン エイ． ジュディス、
スティーブン エイ． ジュディス、
ダニエル シェーファー、
ダニエル シェーファー、
ブレック パーカー、
ブレック パーカー、
Original Assignee
エンバイロロジックス インコーポレイテッド
エンバイロロジックス インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55761744&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2017536813(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by エンバイロロジックス インコーポレイテッド, エンバイロロジックス インコーポレイテッド filed Critical エンバイロロジックス インコーポレイテッド
Publication of JP2017536813A publication Critical patent/JP2017536813A/ja
Publication of JP2017536813A5 publication Critical patent/JP2017536813A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2017521095A 2014-10-20 2015-10-20 Ｒｎａウイルスを検出するための組成物及び方法 Pending JP2017536813A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462066277P 2014-10-20 2014-10-20
US62/066,277 2014-10-20
US201562104008P 2015-01-15 2015-01-15
US62/104,008 2015-01-15
PCT/US2015/056491 WO2016064894A2 (en) 2014-10-20 2015-10-20 Compositions and methods for detecting an rna virus

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020189107A Division JP7114676B2 (ja) 2014-10-20 2020-11-13 Ｒｎａウイルスを検出するための組成物及び方法

Publications (2)

Publication Number Publication Date
JP2017536813A true JP2017536813A (ja) 2017-12-14
JP2017536813A5 JP2017536813A5 (enExample) 2018-12-06

Family

ID=55761744

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017521095A Pending JP2017536813A (ja) 2014-10-20 2015-10-20 Ｒｎａウイルスを検出するための組成物及び方法
JP2020189107A Active JP7114676B2 (ja) 2014-10-20 2020-11-13 Ｒｎａウイルスを検出するための組成物及び方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2020189107A Active JP7114676B2 (ja) 2014-10-20 2020-11-13 Ｒｎａウイルスを検出するための組成物及び方法

Country Status (9)

Country Link
US (3) US10793922B2 (enExample)
EP (2) EP4141128A1 (enExample)
JP (2) JP2017536813A (enExample)
CN (1) CN107208137A (enExample)
AU (2) AU2015336086C1 (enExample)
BR (1) BR112017008082A2 (enExample)
CA (1) CA2965137A1 (enExample)
MX (1) MX2017005159A (enExample)
WO (1) WO2016064894A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7602238B2 (ja) 2019-03-07 2024-12-18 国立大学法人 長崎大学 Ｔｅｒｔプロモーター変異を検出するプローブセット

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2810856C (en) 2010-08-13 2022-05-17 Envirologix Inc. Compositions and methods for quantifying a nucleic acid sequence in a sample
WO2013066438A2 (en) 2011-07-22 2013-05-10 President And Fellows Of Harvard College Evaluation and improvement of nuclease cleavage specificity
NZ723570A (en) 2012-04-09 2018-06-29 Envirologix Inc Compositions and methods for quantifying a nucleic acid sequence in a sample
US9163284B2 (en) 2013-08-09 2015-10-20 President And Fellows Of Harvard College Methods for identifying a target site of a Cas9 nuclease
US9359599B2 (en) 2013-08-22 2016-06-07 President And Fellows Of Harvard College Engineered transcription activator-like effector (TALE) domains and uses thereof
US9322037B2 (en) 2013-09-06 2016-04-26 President And Fellows Of Harvard College Cas9-FokI fusion proteins and uses thereof
US9340799B2 (en) 2013-09-06 2016-05-17 President And Fellows Of Harvard College MRNA-sensing switchable gRNAs
US9526784B2 (en) 2013-09-06 2016-12-27 President And Fellows Of Harvard College Delivery system for functional nucleases
US20150166984A1 (en) 2013-12-12 2015-06-18 President And Fellows Of Harvard College Methods for correcting alpha-antitrypsin point mutations
CN106460071B (zh) 2014-04-22 2021-09-10 一龙公司 增强和/或预测dna扩增的组合物和方法
AU2015298571B2 (en) 2014-07-30 2020-09-03 President And Fellows Of Harvard College Cas9 proteins including ligand-dependent inteins
BR112017008082A2 (pt) 2014-10-20 2017-12-26 Envirologix Inc composições e métodos para detectar um vírus de rna
WO2017070632A2 (en) 2015-10-23 2017-04-27 President And Fellows Of Harvard College Nucleobase editors and uses thereof
WO2018013579A1 (en) * 2016-07-11 2018-01-18 cARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY Sweat as a biofluid for analysis and disease identification
WO2018027078A1 (en) 2016-08-03 2018-02-08 President And Fellows Of Harard College Adenosine nucleobase editors and uses thereof
AU2017308889B2 (en) 2016-08-09 2023-11-09 President And Fellows Of Harvard College Programmable Cas9-recombinase fusion proteins and uses thereof
WO2018039438A1 (en) 2016-08-24 2018-03-01 President And Fellows Of Harvard College Incorporation of unnatural amino acids into proteins using base editing
KR20240007715A (ko) 2016-10-14 2024-01-16 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 핵염기 에디터의 aav 전달
WO2018119359A1 (en) 2016-12-23 2018-06-28 President And Fellows Of Harvard College Editing of ccr5 receptor gene to protect against hiv infection
WO2018165504A1 (en) 2017-03-09 2018-09-13 President And Fellows Of Harvard College Suppression of pain by gene editing
KR20190123328A (ko) 2017-03-09 2019-10-31 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 암 백신
CN110914310A (zh) 2017-03-10 2020-03-24 哈佛大学的校长及成员们 胞嘧啶至鸟嘌呤碱基编辑器
CN111108220B (zh) * 2017-03-15 2024-11-19 博德研究所 用于病毒检测的基于crispr效应系统的诊断
IL306092A (en) 2017-03-23 2023-11-01 Harvard College Nucleic base editors that include nucleic acid programmable DNA binding proteins
US11560566B2 (en) 2017-05-12 2023-01-24 President And Fellows Of Harvard College Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation
EP3658573A1 (en) 2017-07-28 2020-06-03 President and Fellows of Harvard College Methods and compositions for evolving base editors using phage-assisted continuous evolution (pace)
EP3676376B1 (en) 2017-08-30 2025-01-15 President and Fellows of Harvard College High efficiency base editors comprising gam
CA3082251A1 (en) 2017-10-16 2019-04-25 The Broad Institute, Inc. Uses of adenosine base editors
US12406749B2 (en) 2017-12-15 2025-09-02 The Broad Institute, Inc. Systems and methods for predicting repair outcomes in genetic engineering
CN112899350B (zh) * 2018-05-14 2023-01-24 北京艾克伦医疗科技有限公司 核酸检测方法和试剂盒
WO2019226953A1 (en) 2018-05-23 2019-11-28 The Broad Institute, Inc. Base editors and uses thereof
EP3820495A4 (en) 2018-07-09 2022-07-20 The Broad Institute Inc. RNA-PROGRAMMABLE EPIGENETIC RNA MODIFIERS AND THEIR USES
WO2020092453A1 (en) 2018-10-29 2020-05-07 The Broad Institute, Inc. Nucleobase editors comprising geocas9 and uses thereof
CN109593863A (zh) * 2018-11-28 2019-04-09 江南大学 一种链置换型dna聚合酶诱导等温循环扩增反应检测肉类来源的方法
US12351837B2 (en) 2019-01-23 2025-07-08 The Broad Institute, Inc. Supernegatively charged proteins and uses thereof
WO2020191241A1 (en) 2019-03-19 2020-09-24 The Broad Institute, Inc. Methods and compositions for editing nucleotide sequences
WO2020214842A1 (en) 2019-04-17 2020-10-22 The Broad Institute, Inc. Adenine base editors with reduced off-target effects
US12435330B2 (en) 2019-10-10 2025-10-07 The Broad Institute, Inc. Methods and compositions for prime editing RNA
CN111424116B (zh) * 2020-03-19 2023-06-23 首都儿科研究所 用于检测黄热病毒疫苗株的rt-lamp试剂盒及其专用引物和应用
CN111334610B (zh) * 2020-03-20 2023-11-14 广东省妇幼保健院 一种登革病毒通用型rt-raa-lfd扩增引物及检测方法
CN111471797B (zh) * 2020-04-16 2023-05-12 广东省实验动物监测所 用于检测猫冠状病毒的rt-rpa引物对、探针、试剂盒及检测方法
CA3177481A1 (en) 2020-05-08 2021-11-11 David R. Liu Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence
WO2022011215A1 (en) * 2020-07-10 2022-01-13 The Rockefeller University Method and system for saliva testing for virus including covid-19
JP2022060807A (ja) * 2020-10-05 2022-04-15 キヤノンメディカルシステムズ株式会社 乾燥試薬、試薬キット、乾燥試薬の製造方法、分析方法及び核酸増幅方法
EP4669769A1 (en) * 2023-02-14 2025-12-31 Ador Diagnostics Ltd Rolling circle amplification based on an amplicon
CN116574844B (zh) * 2023-03-01 2024-02-27 宁夏大学 一组检测牛病毒性腹泻病毒的rpa引物对、试剂盒和检测方法
CN121272122B (zh) * 2025-12-10 2026-03-24 中国海关科学技术研究中心 一种登革病毒装甲rna标准物质及其制备方法和应用

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010505396A (ja) * 2006-10-06 2010-02-25 ディーエヌエー ジェノテック インク リボ核酸を抽出するための安定化組成物および方法
JP2010533494A (ja) * 2007-07-14 2010-10-28 イオニアン テクノロジーズ， インコーポレイテッド 核酸の指数関数的増幅のためのニック形成および伸長増殖
US20130217071A1 (en) * 2011-12-30 2013-08-22 Luz Montesclaros Methods and compositions for performing nucleic acid amplification reactions
WO2013155056A1 (en) * 2012-04-09 2013-10-17 Envirologix Inc. Compositions and methods for quantifying a nucleic acid sequence in a sample
US20130280706A1 (en) * 2010-08-13 2013-10-24 Envirologix Inc. Compositions and Methods for Quantifying a Nucleic Acid Sequence in a Sample
JP2014082936A (ja) * 2012-10-19 2014-05-12 Kyoto Univ 変異型逆転写酵素

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5455166A (en) 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
US6090555A (en) 1997-12-11 2000-07-18 Affymetrix, Inc. Scanned image alignment systems and methods
US5571639A (en) 1994-05-24 1996-11-05 Affymax Technologies N.V. Computer-aided engineering system for design of sequence arrays and lithographic masks
US6593086B2 (en) * 1996-05-20 2003-07-15 Mount Sinai School Of Medicine Of New York University Nucleic acid amplification methods
US5795716A (en) 1994-10-21 1998-08-18 Chee; Mark S. Computer-aided visualization and analysis system for sequence evaluation
US5629179A (en) 1995-03-17 1997-05-13 Novagen, Inc. Method and kit for making CDNA library
US5733729A (en) 1995-09-14 1998-03-31 Affymetrix, Inc. Computer-aided probability base calling for arrays of nucleic acid probes on chips
JP2000505312A (ja) 1996-03-18 2000-05-09 モレキュラー バイオロジー リソーシーズ，インコーポレイテッド 標的核酸配列増幅
EP0912767B1 (en) 1996-07-16 2006-09-13 Gen-Probe Incorporated Methods for detecting and amplifying nucleic acid sequences using modified oligonucleotides having increased target specific tm
US6117634A (en) * 1997-03-05 2000-09-12 The Reagents Of The University Of Michigan Nucleic acid sequencing and mapping
US6586806B1 (en) 1997-06-20 2003-07-01 Cypress Semiconductor Corporation Method and structure for a single-sided non-self-aligned transistor
US6484183B1 (en) 1997-07-25 2002-11-19 Affymetrix, Inc. Method and system for providing a polymorphism database
GB9716231D0 (en) 1997-07-31 1997-10-08 Amersham Int Ltd Base analogues
ATE280246T1 (de) 1997-08-15 2004-11-15 Affymetrix Inc Polymorphismuserkennung mit hilfe cluster-analyse
AU1366299A (en) 1997-10-27 1999-05-17 Boston Probes, Inc. Methods, kits and compositions pertaining to pna molecular beacons
US5952202A (en) 1998-03-26 1999-09-14 The Perkin Elmer Corporation Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification
JP3565025B2 (ja) 1998-07-07 2004-09-15 日産自動車株式会社 治具交換装置および治具交換方法
US6185561B1 (en) 1998-09-17 2001-02-06 Affymetrix, Inc. Method and apparatus for providing and expression data mining database
WO2000070095A2 (en) * 1999-05-17 2000-11-23 Dade Behring Inc. Homogeneous isothermal amplification and detection of nucleic acids using a template switch oligonucleotide
US6436677B1 (en) 2000-03-02 2002-08-20 Promega Corporation Method of reverse transcription
ATE312942T1 (de) 2000-10-25 2005-12-15 Hoffmann La Roche Amplifizierung unter verwendung von modifizierten primern
EP1353936A4 (en) 2000-12-27 2005-05-18 Invitrogen Corp PRIMER AND METHOD FOR THE DETECTION AND DISTINCTION OF NUCLEIC ACIDS
US20020183936A1 (en) 2001-01-24 2002-12-05 Affymetrix, Inc. Method, system, and computer software for providing a genomic web portal
EP1470250A2 (en) 2001-07-15 2004-10-27 Keck Graduate Institute Gene expression analysis using nicking agents
WO2003008624A2 (en) 2001-07-15 2003-01-30 Keck Graduate Institute Nucleic acid amplification using nicking agents
US6585606B2 (en) 2001-07-16 2003-07-01 Thomas S. Penrose Golf club accessory
US7056671B2 (en) 2001-08-20 2006-06-06 Takara Bio Inc. Isothermal chimeric primer nucleic acid amplification methods using blocking oglionucleotide
US6617137B2 (en) 2001-10-15 2003-09-09 Molecular Staging Inc. Method of amplifying whole genomes without subjecting the genome to denaturing conditions
US6977148B2 (en) 2001-10-15 2005-12-20 Qiagen Gmbh Multiple displacement amplification
US20030211483A1 (en) * 2002-05-09 2003-11-13 Schroeder Benjamin G. Methods for the enrichment of low-abundance polynucleotides
US7662594B2 (en) * 2002-09-20 2010-02-16 New England Biolabs, Inc. Helicase-dependent amplification of RNA
AU2003272438B2 (en) 2002-09-20 2009-04-02 New England Biolabs, Inc. Helicase dependent amplification of nucleic acids
JP4380305B2 (ja) 2003-11-21 2009-12-09 味の素株式会社 発酵法によるｌ−アミノ酸の製造法
WO2005087952A1 (en) 2004-03-05 2005-09-22 The Regents Of The University Of California Methods and compositions relating to the pharmacogenetics of abcc2, ugt1a1, and/or slc01b1 gene variants
US20060115838A1 (en) 2004-10-19 2006-06-01 Trevigen Inc. Real-time detection of amplicons using nucleic acid repair enzymes
WO2006074162A2 (en) 2005-01-04 2006-07-13 Hitachi Chemical Company, Ltd. Primer generation rolling circle amplification
EP2829615B1 (en) 2005-07-25 2018-05-09 Alere San Diego, Inc. Kit for multiplexing recombinase polymerase amplification
DK1924704T3 (da) 2005-08-02 2011-09-05 Rubicon Genomics Inc Sammensætninger og fremgangsmåder til bearbejdning og mangfoldiggørelse af DNA, herunder ved anvendelse af flere enzymer i en enkelt reaktion
CA2621932A1 (en) * 2005-09-14 2007-03-22 Human Genetic Signatures Pty Ltd Assay for hpv and methylated genomic dna targets to screen for cervical cancer
US7947286B2 (en) 2005-10-07 2011-05-24 Panthera Biopharma Llc Drosophila cell lines producing recombinant secretable filovirus surface glycoproteins lacking the membrane spanning domain
EP1951888B1 (en) * 2005-11-09 2012-09-05 PrimeraDx, Inc. Multiplexed quantitative detection of pathogens
US8673567B2 (en) * 2006-03-08 2014-03-18 Atila Biosystems, Inc. Method and kit for nucleic acid sequence detection
CN100489112C (zh) * 2006-03-10 2009-05-20 杭州优思达生物技术有限公司 切口酶扩增靶核酸序列的方法及用于扩增靶核酸序列的试剂盒及其应用
US20090092967A1 (en) 2006-06-26 2009-04-09 Epoch Biosciences, Inc. Method for generating target nucleic acid sequences
EP2071927A2 (en) 2006-09-28 2009-06-24 Illumina, Inc. Compositions and methods for nucleotide sequencing
JP2008136451A (ja) * 2006-12-05 2008-06-19 Hitachi Ltd 核酸増幅法
US20080254458A1 (en) 2007-04-10 2008-10-16 Asiagen Corporation Method of pre-treating in pleural effusion for detection of Mycobacterium tuberculosis
US20080274458A1 (en) 2007-05-01 2008-11-06 Latham Gary J Nucleic acid quantitation methods
WO2009020609A2 (en) * 2007-08-06 2009-02-12 Nanogen, Inc. Isolation of nucleic acids molecules using modified solid supports
US20090197254A1 (en) 2007-12-14 2009-08-06 Ming-Chou Lee Variant scorpion primers for nucleic acid amplification and detection
EP3150727B1 (en) 2008-04-30 2019-07-10 Integrated DNA Technologies Inc. Rnase-h-based assays utilizing modified rna monomers
US10760074B2 (en) * 2008-09-03 2020-09-01 Takara Bio Inc. Composition for detection of RNA
EP2379719A4 (en) * 2009-01-21 2012-10-03 Human Genetic Signatures Pty IMPROVED ISOTHERMAL STRANDSHIFT REINFORCEMENT
CN102428191A (zh) 2009-03-18 2012-04-25 塞昆纳姆股份有限公司 热稳定性内切核酸酶在产生报道分子中的应用
WO2010126913A1 (en) 2009-04-27 2010-11-04 Gen-Probe Incorporated Methods and kits for use in the selective amplification of target sequences
EP2420579A1 (en) 2010-08-17 2012-02-22 QIAGEN GmbH Helicase dependent isothermal amplification using nicking enzymes
DK2756101T3 (en) 2011-09-15 2018-08-27 David A Shafer PROBLEMS: ANTISON DETAIL COMPOSITIONS FOR DETECTING HIGH OR SPECIFIC DNA OR RNA
EP2867366B1 (en) * 2012-06-29 2018-05-16 General Electric Company Method for isothermal dna amplification starting from an rna template in a single reaction mixture
CN106460071B (zh) 2014-04-22 2021-09-10 一龙公司 增强和/或预测dna扩增的组合物和方法
CN106574299A (zh) 2014-04-30 2017-04-19 龙公司 用来检测黄龙病的组合物和方法
BR112017008082A2 (pt) 2014-10-20 2017-12-26 Envirologix Inc composições e métodos para detectar um vírus de rna
CA2965657A1 (en) 2014-10-28 2016-05-06 Envirologix Inc. Sample preparation vessels, microfluidic circuits, and systems and methods for sample preparation, extraction, and analysis
WO2016122698A1 (en) 2015-01-30 2016-08-04 Envirologix, Inc. Compositions and methods for rapid detection of salmonella

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010505396A (ja) * 2006-10-06 2010-02-25 ディーエヌエー ジェノテック インク リボ核酸を抽出するための安定化組成物および方法
JP2010533494A (ja) * 2007-07-14 2010-10-28 イオニアン テクノロジーズ， インコーポレイテッド 核酸の指数関数的増幅のためのニック形成および伸長増殖
US20130280706A1 (en) * 2010-08-13 2013-10-24 Envirologix Inc. Compositions and Methods for Quantifying a Nucleic Acid Sequence in a Sample
US20130217071A1 (en) * 2011-12-30 2013-08-22 Luz Montesclaros Methods and compositions for performing nucleic acid amplification reactions
WO2013155056A1 (en) * 2012-04-09 2013-10-17 Envirologix Inc. Compositions and methods for quantifying a nucleic acid sequence in a sample
JP2014082936A (ja) * 2012-10-19 2014-05-12 Kyoto Univ 変異型逆転写酵素

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7602238B2 (ja) 2019-03-07 2024-12-18 国立大学法人 長崎大学 Ｔｅｒｔプロモーター変異を検出するプローブセット

Also Published As

Publication number Publication date
AU2015336086C1 (en) 2021-07-29
WO2016064894A2 (en) 2016-04-28
EP3209802A2 (en) 2017-08-30
WO2016064894A3 (en) 2016-06-09
US20210025016A1 (en) 2021-01-28
EP4141128A1 (en) 2023-03-01
AU2021201378A1 (en) 2021-03-18
EP3209802A4 (en) 2018-04-25
JP7114676B2 (ja) 2022-08-08
CN107208137A (zh) 2017-09-26
EP3209802B1 (en) 2022-09-07
AU2015336086B2 (en) 2020-12-03
HK1243463A1 (en) 2018-07-13
JP2021045140A (ja) 2021-03-25
CA2965137A1 (en) 2016-04-28
AU2015336086A1 (en) 2017-05-11
AU2021201378B2 (en) 2023-05-25
MX2017005159A (es) 2017-08-18
BR112017008082A2 (pt) 2017-12-26
US20170327911A1 (en) 2017-11-16
US20260092337A1 (en) 2026-04-02
US12392001B2 (en) 2025-08-19
US10793922B2 (en) 2020-10-06

Similar Documents

Publication Publication Date Title
JP7114676B2 (ja) Ｒｎａウイルスを検出するための組成物及び方法
US12258637B2 (en) Compositions and methods for enhancing and/or predicting DNA amplification
JP6821531B2 (ja) プロセシングしていない試料において、関心対象の核酸の量を決定するための方法
US7595163B2 (en) Method for detecting SARS coronavirus
US11926877B2 (en) Saliva-based molecular testing for SARS-CoV-2
Maiti et al. Isothermal amplification‐based assays for rapid and sensitive detection of severe acute respiratory syndrome coronavirus 2: Opportunities and recent developments
JP7004570B2 (ja) 基質分子
JP2023519919A (ja) 病原体を検出するためのアッセイ
JP7385471B2 (ja) Ｐｈｉ６内部対照組成物、装置、および方法
HK1243463B (en) Compositions and methods for detecting an rna virus
CA2946737C (en) Compositions and methods for enhancing and/or predicting dna amplification
Mahali et al. Duplex SYBR RT-qPCR for SARS-CoV-2 Detection in Malaysia: Duplex SYBR RT-qPCR for SARS-CoV-2 Detection in Malaysia
JP2023530751A (ja) サンプル中のウイルスを特徴付けるためのキット及び方法
Qu An Overview of RT-PCR in SARS-CoV-2 Detection and Comparison to Other Methods

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20181022

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20181022

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20191105

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20200205

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20200714