CA2965137A1 - Compositions and methods for detecting an rna virus - Google Patents
Compositions and methods for detecting an rna virus Download PDFInfo
- Publication number
- CA2965137A1 CA2965137A1 CA2965137A CA2965137A CA2965137A1 CA 2965137 A1 CA2965137 A1 CA 2965137A1 CA 2965137 A CA2965137 A CA 2965137A CA 2965137 A CA2965137 A CA 2965137A CA 2965137 A1 CA2965137 A1 CA 2965137A1
- Authority
- CA
- Canada
- Prior art keywords
- primer
- virus
- kit
- sample
- primers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462066277P | 2014-10-20 | 2014-10-20 | |
| US62/066,277 | 2014-10-20 | ||
| US201562104008P | 2015-01-15 | 2015-01-15 | |
| US62/104,008 | 2015-01-15 | ||
| PCT/US2015/056491 WO2016064894A2 (en) | 2014-10-20 | 2015-10-20 | Compositions and methods for detecting an rna virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2965137A1 true CA2965137A1 (en) | 2016-04-28 |
Family
ID=55761744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2965137A Pending CA2965137A1 (en) | 2014-10-20 | 2015-10-20 | Compositions and methods for detecting an rna virus |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10793922B2 (enExample) |
| EP (2) | EP4141128A1 (enExample) |
| JP (2) | JP2017536813A (enExample) |
| CN (1) | CN107208137A (enExample) |
| AU (2) | AU2015336086C1 (enExample) |
| BR (1) | BR112017008082A2 (enExample) |
| CA (1) | CA2965137A1 (enExample) |
| MX (1) | MX2017005159A (enExample) |
| WO (1) | WO2016064894A2 (enExample) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112013004044A2 (pt) | 2010-08-13 | 2016-07-05 | Envirologix Inc | composições e métodos para quantificação de uma sequência de ácido nucleico em uma amostra. |
| US10323236B2 (en) | 2011-07-22 | 2019-06-18 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| KR102159818B1 (ko) | 2012-04-09 | 2020-09-25 | 엔바이로로직스 인크. | 시료 내 핵산 서열을 정량화하기 위한 조성물 및 방법 |
| US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9340799B2 (en) | 2013-09-06 | 2016-05-17 | President And Fellows Of Harvard College | MRNA-sensing switchable gRNAs |
| US9322037B2 (en) | 2013-09-06 | 2016-04-26 | President And Fellows Of Harvard College | Cas9-FokI fusion proteins and uses thereof |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US11053481B2 (en) | 2013-12-12 | 2021-07-06 | President And Fellows Of Harvard College | Fusions of Cas9 domains and nucleic acid-editing domains |
| US11505836B2 (en) | 2014-04-22 | 2022-11-22 | Envirologix Inc. | Compositions and methods for enhancing and/or predicting DNA amplification |
| EP4079847A1 (en) | 2014-07-30 | 2022-10-26 | President And Fellows Of Harvard College | Cas9 proteins including ligand-dependent inteins |
| AU2015336086C1 (en) | 2014-10-20 | 2021-07-29 | Envirologix Inc. | Compositions and methods for detecting an RNA virus |
| IL294014B2 (en) | 2015-10-23 | 2024-07-01 | Harvard College | Nucleobase editors and uses thereof |
| WO2018013579A1 (en) * | 2016-07-11 | 2018-01-18 | cARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | Sweat as a biofluid for analysis and disease identification |
| WO2018027078A1 (en) | 2016-08-03 | 2018-02-08 | President And Fellows Of Harard College | Adenosine nucleobase editors and uses thereof |
| US11661590B2 (en) | 2016-08-09 | 2023-05-30 | President And Fellows Of Harvard College | Programmable CAS9-recombinase fusion proteins and uses thereof |
| US11542509B2 (en) | 2016-08-24 | 2023-01-03 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| SG11201903089RA (en) | 2016-10-14 | 2019-05-30 | Harvard College | Aav delivery of nucleobase editors |
| US10745677B2 (en) | 2016-12-23 | 2020-08-18 | President And Fellows Of Harvard College | Editing of CCR5 receptor gene to protect against HIV infection |
| EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
| EP3592381A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Cancer vaccine |
| CN110914310A (zh) | 2017-03-10 | 2020-03-24 | 哈佛大学的校长及成员们 | 胞嘧啶至鸟嘌呤碱基编辑器 |
| CN111108220B (zh) * | 2017-03-15 | 2024-11-19 | 博德研究所 | 用于病毒检测的基于crispr效应系统的诊断 |
| GB2575930A (en) | 2017-03-23 | 2020-01-29 | Harvard College | Nucleobase editors comprising nucleic acid programmable DNA binding proteins |
| WO2018209320A1 (en) | 2017-05-12 | 2018-11-15 | President And Fellows Of Harvard College | Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation |
| US11732274B2 (en) | 2017-07-28 | 2023-08-22 | President And Fellows Of Harvard College | Methods and compositions for evolving base editors using phage-assisted continuous evolution (PACE) |
| EP3676376B1 (en) | 2017-08-30 | 2025-01-15 | President and Fellows of Harvard College | High efficiency base editors comprising gam |
| WO2019079347A1 (en) | 2017-10-16 | 2019-04-25 | The Broad Institute, Inc. | USES OF BASIC EDITORS ADENOSINE |
| WO2019118949A1 (en) | 2017-12-15 | 2019-06-20 | The Broad Institute, Inc. | Systems and methods for predicting repair outcomes in genetic engineering |
| CN108588050B (zh) * | 2018-05-14 | 2021-06-25 | 北京艾克伦医疗科技有限公司 | Dna聚合酶以及核酸检测方法和试剂盒 |
| WO2019226953A1 (en) | 2018-05-23 | 2019-11-28 | The Broad Institute, Inc. | Base editors and uses thereof |
| WO2020092453A1 (en) | 2018-10-29 | 2020-05-07 | The Broad Institute, Inc. | Nucleobase editors comprising geocas9 and uses thereof |
| CN109593863A (zh) * | 2018-11-28 | 2019-04-09 | 江南大学 | 一种链置换型dna聚合酶诱导等温循环扩增反应检测肉类来源的方法 |
| US12351837B2 (en) | 2019-01-23 | 2025-07-08 | The Broad Institute, Inc. | Supernegatively charged proteins and uses thereof |
| JP7602238B2 (ja) | 2019-03-07 | 2024-12-18 | 国立大学法人 長崎大学 | Tertプロモーター変異を検出するプローブセット |
| DE112020001342T5 (de) | 2019-03-19 | 2022-01-13 | President and Fellows of Harvard College | Verfahren und Zusammensetzungen zum Editing von Nukleotidsequenzen |
| WO2020214842A1 (en) | 2019-04-17 | 2020-10-22 | The Broad Institute, Inc. | Adenine base editors with reduced off-target effects |
| WO2021072328A1 (en) | 2019-10-10 | 2021-04-15 | The Broad Institute, Inc. | Methods and compositions for prime editing rna |
| CN111424116B (zh) * | 2020-03-19 | 2023-06-23 | 首都儿科研究所 | 用于检测黄热病毒疫苗株的rt-lamp试剂盒及其专用引物和应用 |
| CN111334610B (zh) * | 2020-03-20 | 2023-11-14 | 广东省妇幼保健院 | 一种登革病毒通用型rt-raa-lfd扩增引物及检测方法 |
| CN111471797B (zh) * | 2020-04-16 | 2023-05-12 | 广东省实验动物监测所 | 用于检测猫冠状病毒的rt-rpa引物对、探针、试剂盒及检测方法 |
| GB2614813B (en) | 2020-05-08 | 2025-05-07 | Harvard College | Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence |
| US20230279511A1 (en) * | 2020-07-10 | 2023-09-07 | The Rockefeller University | Method and system for saliva testing for virus including covid-19 |
| JP2022060807A (ja) * | 2020-10-05 | 2022-04-15 | キヤノンメディカルシステムズ株式会社 | 乾燥試薬、試薬キット、乾燥試薬の製造方法、分析方法及び核酸増幅方法 |
| WO2024171191A1 (en) * | 2023-02-14 | 2024-08-22 | Ador Diagnostics Ltd | Amplicon based rolling circle amplification |
| CN116574844B (zh) * | 2023-03-01 | 2024-02-27 | 宁夏大学 | 一组检测牛病毒性腹泻病毒的rpa引物对、试剂盒和检测方法 |
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| AU2015336086C1 (en) | 2014-10-20 | 2021-07-29 | Envirologix Inc. | Compositions and methods for detecting an RNA virus |
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-
2015
- 2015-10-20 AU AU2015336086A patent/AU2015336086C1/en active Active
- 2015-10-20 EP EP22187762.4A patent/EP4141128A1/en active Pending
- 2015-10-20 US US15/520,328 patent/US10793922B2/en active Active
- 2015-10-20 BR BR112017008082A patent/BR112017008082A2/pt unknown
- 2015-10-20 JP JP2017521095A patent/JP2017536813A/ja active Pending
- 2015-10-20 WO PCT/US2015/056491 patent/WO2016064894A2/en not_active Ceased
- 2015-10-20 EP EP15852795.2A patent/EP3209802B1/en not_active Revoked
- 2015-10-20 CA CA2965137A patent/CA2965137A1/en active Pending
- 2015-10-20 MX MX2017005159A patent/MX2017005159A/es unknown
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| AU2021201378A1 (en) | 2021-03-18 |
| WO2016064894A2 (en) | 2016-04-28 |
| EP4141128A1 (en) | 2023-03-01 |
| AU2015336086C1 (en) | 2021-07-29 |
| EP3209802A4 (en) | 2018-04-25 |
| AU2015336086A1 (en) | 2017-05-11 |
| JP7114676B2 (ja) | 2022-08-08 |
| CN107208137A (zh) | 2017-09-26 |
| EP3209802B1 (en) | 2022-09-07 |
| US12392001B2 (en) | 2025-08-19 |
| HK1243463A1 (en) | 2018-07-13 |
| US20210025016A1 (en) | 2021-01-28 |
| JP2017536813A (ja) | 2017-12-14 |
| AU2015336086B2 (en) | 2020-12-03 |
| US20170327911A1 (en) | 2017-11-16 |
| MX2017005159A (es) | 2017-08-18 |
| AU2021201378B2 (en) | 2023-05-25 |
| US10793922B2 (en) | 2020-10-06 |
| EP3209802A2 (en) | 2017-08-30 |
| JP2021045140A (ja) | 2021-03-25 |
| BR112017008082A2 (pt) | 2017-12-26 |
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